Christian Betzel Institute for Biochemistry and Molecular Biology, Laboratory for Structural Biology of Infection and Inflammation c/o DESY University of Hamburg Biography Publications Institution JoVE Articles Christian Betzel has not added a biography. If you are Christian Betzel and would like to personalize this page please email our Author Liaison for assistance. Publications Crystal Structure of Mistletoe Lectin I (ML-I) from Viscum Album in Complex with 4-N-Furfurylcytosine at 2.85 Å Resolution Medicinal Chemistry (Shariqah (United Arab Emirates)). May, 2018 | Pubmed ID: 29792147 Thrombin-like Enzymes from Snake Venom: Structural Characterization and Mechanism of Action International Journal of Biological Macromolecules. Mar, 2018 | Pubmed ID: 29604354 Highly Affine and Selective Aptamers Against Cholera Toxin As Capture Elements in Magnetic Bead-based Sandwich ELAA Journal of Biotechnology. Mar, 2018 | Pubmed ID: 29408200 Spider's Venom Phospholipases D: A Structural Review International Journal of Biological Macromolecules. Feb, 2018 | Pubmed ID: 28951301 Protein Profile Analysis of Two Australian Snake Venoms by One- Dimensional Gel Electrophoresis and MS/MS Experiments Current Medicinal Chemistry. 2017 | Pubmed ID: 28571558 Analysis of Self-assembly of S-layer Protein Slp-B53 from Lysinibacillus Sphaericus European Biophysics Journal : EBJ. Jan, 2017 | Pubmed ID: 27270294 A Multicrystal Diffraction Data-collection Approach for Studying Structural Dynamics with Millisecond Temporal Resolution IUCrJ. Nov, 2016 | Pubmed ID: 27840678 Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells PLoS Pathogens. Jun, 2016 | Pubmed ID: 27300509 Atomic Structure and Biochemical Characterization of an RNA Endonuclease in the N Terminus of Andes Virus L Protein PLoS Pathogens. Jun, 2016 | Pubmed ID: 27300328 Two Variants of the Major Serine Protease Inhibitor from the Sea Anemone Stichodactyla Helianthus, Expressed in Pichia Pastoris Protein Expression and Purification. 07, 2016 | Pubmed ID: 26993255 Structural Investigation of the Thymidine Phosphorylase from Salmonella Typhimurium in the Unliganded State and Its Complexes with Thymidine and Uridine Acta Crystallographica. Section F, Structural Biology Communications. Mar, 2016 | Pubmed ID: 26919527 Isolation and Characterization of Bradykinin Potentiating Peptides from Agkistrodon Bilineatus Venom Proteome Science. 2016 | Pubmed ID: 26770072 Exosomal Cellular Prion Protein Drives Fibrillization of Amyloid Beta and Counteracts Amyloid Beta-mediated Neurotoxicity Journal of Neurochemistry. Apr, 2016 | Pubmed ID: 26710111 In Vivo Protein Crystallization in Combination with Highly Brilliant Radiation Sources Offers Novel Opportunities for the Structural Analysis of Post-translationally Modified Eukaryotic Proteins Acta Crystallographica. Section F, Structural Biology Communications. Aug, 2015 | Pubmed ID: 26249677 Introduction to Selected Articles from the 15th ICCBM Acta Crystallographica. Section F, Structural Biology Communications. Jul, 2015 | Pubmed ID: 26144223 High Resolution Structures of Plasmodium Falciparum GST Complexes Provide Novel Insights into the Dimer-tetramer Transition and a Novel Ligand-binding Site Journal of Structural Biology. Sep, 2015 | Pubmed ID: 26072058 Crystal Structure of a Mirror-image L-RNA Aptamer (Spiegelmer) in Complex with the Natural L-protein Target CCL2 Nature Communications. Apr, 2015 | Pubmed ID: 25901662 Three-dimensional Structure of a Kunitz-type Inhibitor in Complex with an Elastase-like Enzyme The Journal of Biological Chemistry. May, 2015 | Pubmed ID: 25878249 Latest Methods of Fluorescence-based Protein Crystal Identification Acta Crystallographica. Section F, Structural Biology Communications. Feb, 2015 | Pubmed ID: 25664782 Systematic Analysis of Protein-detergent Complexes Applying Dynamic Light Scattering to Optimize Solutions for Crystallization Trials Acta Crystallographica. Section F, Structural Biology Communications. Jan, 2015 | Pubmed ID: 25615974 Isolation, Identification and Functional Profile of Excretory-secretory Peptides from Onchocerca Ochengi Acta Tropica. Feb, 2015 | Pubmed ID: 25479441 Utilisation of Adsorption and Desorption for Simultaneously Improving Protein Crystallisation Success Rate and Crystal Quality Scientific Reports. Dec, 2014 | Pubmed ID: 25471817 Structure-based Identification of Inositol Polyphosphate 1-phosphatase from Entamoeba Histolytica Acta Crystallographica. Section D, Biological Crystallography. Nov, 2014 | Pubmed ID: 25372691 Room-temperature Macromolecular Serial Crystallography Using Synchrotron Radiation IUCrJ. Jul, 2014 | Pubmed ID: 25075341 Serial Crystallography on in Vivo Grown Microcrystals Using Synchrotron Radiation IUCrJ. Mar, 2014 | Pubmed ID: 25075324 Preliminary Crystallographic Analysis of a Cruciferin Protein from Seeds of Moringa Oleifera The Protein Journal. Jun, 2014 | Pubmed ID: 24705831 Elapid Snake Venom Analyses Show the Specificity of the Peptide Composition at the Level of Genera Naja and Notechis Toxins. Feb, 2014 | Pubmed ID: 24590383 Crystallization and Preliminary X-ray Study of Vibrio Cholerae Uridine Phosphorylase in Complex with 6-methyluracil Acta Crystallographica. Section F, Structural Biology Communications. Jan, 2014 | Pubmed ID: 24419619 Staphylococcus Aureus Thiaminase II: Oligomerization Warrants Proteolytic Protection Against Serine Proteases Acta Crystallographica. Section D, Biological Crystallography. Dec, 2013 | Pubmed ID: 24311574 Production, Purification and Characterization of Recombinant, Full-length Human Claudin-1 PloS One. 2013 | Pubmed ID: 23704991 Natively Inhibited Trypanosoma Brucei Cathepsin B Structure Determined by Using an X-ray Laser Science (New York, N.Y.). Jan, 2013 | Pubmed ID: 23196907 Structure of the Recombinant BPTI/Kunitz-type Inhibitor RShPI-1A from the Marine Invertebrate Stichodactyla Helianthus Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Nov, 2012 | Pubmed ID: 23143234 Purification, Crystallization and Preliminary X-ray Diffraction Analysis of Crotamine, a Myotoxic Polypeptide from the Brazilian Snake Crotalus Durissus Terrificus Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Sep, 2012 | Pubmed ID: 22949192 Single-drop Optimization of Protein Crystallization Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Aug, 2012 | Pubmed ID: 22869140 Monitoring and Scoring Counter-diffusion Protein Crystallization Experiments in Capillaries by in Situ Dynamic Light Scattering PloS One. 2012 | Pubmed ID: 22675464 Features of "All LNA" Duplexes Showing a New Type of Nucleic Acid Geometry Journal of Nucleic Acids. 2012 | Pubmed ID: 22666550 Crystal Structure of a Dimeric Ser49- PLA₂-like Myotoxic Component of the Vipera Ammodytes Meridionalis Venomics Reveals Determinants of Myotoxicity and Membrane Damaging Activity Molecular BioSystems. Apr, 2012 | Pubmed ID: 22362132 Crystallization and Preliminary X-ray Diffraction Analysis of an L-amino-acid Oxidase from Bothrops Jararacussu Venom Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Feb, 2012 | Pubmed ID: 22298002 In Vivo Protein Crystallization Opens New Routes in Structural Biology Nature Methods. Mar, 2012 | Pubmed ID: 22286384 Heating Affects Structure, Enterocyte Adsorption and Signalling, As Well As Immunogenicity of the Peanut Allergen Ara H 2 The Open Allergy Journal. Dec, 2011 | Pubmed ID: 22318448 Venom Peptide Analysis of Vipera Ammodytes Meridionalis (Viperinae) and Bothrops Jararacussu (Crotalinae) Demonstrates Subfamily-specificity of the Peptidome in the Family Viperidae Molecular BioSystems. Dec, 2011 | Pubmed ID: 21959992 Structure of the Lassa Virus Nucleoprotein Revealed by X-ray Crystallography, Small-angle X-ray Scattering, and Electron Microscopy The Journal of Biological Chemistry. Nov, 2011 | Pubmed ID: 21917929 Three-dimensional Modelling of Honeybee Venom Allergenic Proteases: Relation to Allergenicity Zeitschrift Fur Naturforschung. C, Journal of Biosciences. May-Jun, 2011 | Pubmed ID: 21812349 Purification, Crystallization and Preliminary X-ray Diffraction Analysis of ThiM from Staphylococcus Aureus Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Apr, 2011 | Pubmed ID: 21505246 Pseudechis Australis Venomics: Adaptation for a Defense Against Microbial Pathogens and Recruitment of Body Transferrin Journal of Proteome Research. May, 2011 | Pubmed ID: 21417486 Isolation, Purification, Crystallization and Preliminary Crystallographic Studies of a Chitinase from Crocus Vernus Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Mar, 2011 | Pubmed ID: 21393839 Purification, Crystallization and Preliminary X-ray Diffraction Analysis of the Thiaminase Type II from Staphylococcus Aureus Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Jan, 2011 | Pubmed ID: 21206023 The Structure of a Native L-amino Acid Oxidase, the Major Component of the Vipera Ammodytes Ammodytes Venomic, Reveals Dynamic Active Site and Quaternary Structure Stabilization by Divalent Ions Molecular BioSystems. Feb, 2011 | Pubmed ID: 20938508 CHL1 is a Selective Organizer of the Presynaptic Machinery Chaperoning the SNARE Complex PloS One. Aug, 2010 | Pubmed ID: 20711454 The Crystal Structure of an 'All Locked' Nucleic Acid Duplex Nucleic Acids Research. Oct, 2010 | Pubmed ID: 20530536 Three-dimensional Model of the Honeybee Venom Allergen Api M 7: Structural and Functional Insights Molecular BioSystems. Jun, 2010 | Pubmed ID: 20485747 Efficient UV Detection of Protein Crystals Enabled by Fluorescence Excitation at Wavelengths Longer Than 300 Nm Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Apr, 2010 | Pubmed ID: 20383027 Snake Venomic of Crotalus Durissus Terrificus--correlation with Pharmacological Activities Journal of Proteome Research. May, 2010 | Pubmed ID: 20205475 Crystallization and Preliminary X-ray Diffraction Data of an LNA 7-mer Duplex Derived from a Ricin Aptamer Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Sep, 2009 | Pubmed ID: 19724123 Crystallization and X-ray Diffraction Analysis of an 'all-locked' Nucleic Acid Duplex Derived from a TRNA(Ser) Microhelix Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Aug, 2009 | Pubmed ID: 19652346 Peptide NMHRYPNQ of the Cellular Prion Protein (PrP(C)) Inhibits Aggregation and is a Potential Key for Understanding Prion-prion Interactions Journal of Molecular Biology. Sep, 2009 | Pubmed ID: 19607841 UV-light-induced Conversion and Aggregation of Prion Proteins Free Radical Biology & Medicine. May, 2009 | Pubmed ID: 19249347 Escherichia Coli TRNA(Arg) Acceptor-stem Isoacceptors: Comparative Crystallization and Preliminary X-ray Diffraction Analysis Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Feb, 2009 | Pubmed ID: 19193994 X-ray Diffraction Analysis of a Human TRNA(Gly) Acceptor-stem Microhelix Isoacceptor at 1.18 A Resolution Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Jan, 2009 | Pubmed ID: 19153458 Proteome Analysis of Snake Venom Toxins: Pharmacological Insights Expert Review of Proteomics. Dec, 2008 | Pubmed ID: 19086859 Isolation, Crystallization and Preliminary X-ray Diffraction Analysis of L-amino-acid Oxidase from Vipera Ammodytes Ammodytes Venom Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Oct, 2008 | Pubmed ID: 18931435 Structure of Mistletoe Lectin I from Viscum Album in Complex with the Phytohormone Zeatin Biochimica Et Biophysica Acta. Nov, 2008 | Pubmed ID: 18718563 Autoproteolytic Stability of a Trypsin from the Marine Crab Cancer Pagurus Biochemical and Biophysical Research Communications. Jun, 2008 | Pubmed ID: 18395521 Comparative Analysis of the Venom Proteomes of Vipera Ammodytes Ammodytes and Vipera Ammodytes Meridionalis Journal of Proteome Research. Mar, 2008 | Pubmed ID: 18257516 Human TRNA(Gly) Acceptor-stem Microhelix: Crystallization and Preliminary X-ray Diffraction Analysis at 1.2 A Resolution Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Oct, 2007 | Pubmed ID: 17909289 Isolation, Crystallization and Preliminary Crystallographic Analysis of Salmonella Typhimurium Uridine Phosphorylase Crystallized with 2,2'-anhydrouridine Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Oct, 2007 | Pubmed ID: 17909287 Cocrystallizing Natural RNA with Its Unnatural Mirror Image: Biochemical and Preliminary X-ray Diffraction Analysis of a 5S RRNA A-helix Racemate Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Oct, 2007 | Pubmed ID: 17909284 First Experimental Evidence for the Preferential Stabilization of the Natural D- over the Nonnatural L-configuration in Nucleic Acids RNA (New York, N.Y.). Nov, 2007 | Pubmed ID: 17804644 Crystallization and Preliminary X-ray Diffraction Studies of Trypsin-like Proteases from the Gastric Fluid of the Marine Crab Cancer Pagurus Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Mar, 2007 | Pubmed ID: 17329824 Crystallization and Preliminary X-ray Diffraction Analysis of an Escherichia Coli TRNA(Gly) Acceptor-stem Microhelix Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Jan, 2007 | Pubmed ID: 17183173 Purification, Crystallization and Preliminary X-ray Study of the Fungal Laccase from Cerrena Maxima Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Oct, 2006 | Pubmed ID: 17012782 Catalytic Efficiencies of Alkaline Proteinases from Microorganisms Zeitschrift Fur Naturforschung. C, Journal of Biosciences. May-Jun, 2006 | Pubmed ID: 16869506 Comparative Crystallization and Preliminary X-ray Diffraction Studies of Locked Nucleic Acid and RNA Stems of a Tenascin C-binding Aptamer Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Jul, 2006 | Pubmed ID: 16820689 Crystallization and Preliminary X-ray Diffraction Analysis of a TRNASer Acceptor-stem Microhelix Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Jun, 2006 | Pubmed ID: 16754981 Interactions of Recombinant Prions with Compounds of Therapeutical Significance Biochemical and Biophysical Research Communications. Jun, 2006 | Pubmed ID: 16630566 Mistletoe Lectin I in Complex with Galactose and Lactose Reveals Distinct Sugar-binding Properties Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Jan, 2005 | Pubmed ID: 16508080 Structure of the Major Cytosolic Glutathione S-transferase from the Parasitic Nematode Onchocerca Volvulus The Journal of Biological Chemistry. Apr, 2005 | Pubmed ID: 15640152 Native and Inhibited Structure of a Mu Class-related Glutathione S-transferase from Plasmodium Falciparum The Journal of Biological Chemistry. Jan, 2004 | Pubmed ID: 12972411 Groeiende eiwit kristallen met verschillende afmetingen, met behulp van geautomatiseerde kristallisatie in combinatie met In Situ Dynamische lichtverstrooiing Daniela Baitan1,2, Robin Schubert2,3, Arne Meyer1, Karsten Dierks1, Markus Perbandt2,3, Christian Betzel2,3 1Xtal Concepts GmbH, 2Institute for Biochemistry and Molecular Biology, Laboratory for Structural Biology of Infection and Inflammation c/o DESY, University of Hamburg, 3The Hamburg Center for Ultrafast Imaging, University of Hamburg JoVE 57070 Biochemistry Microfluidic Chips voor In Situ Crystal röntgendiffractie en In Situ Dynamische lichtverstrooiing voor seriële kristallografie Yannig Gicquel*1,2, Robin Schubert*3,4,5, Svetlana Kapis3, Gleb Bourenkov6, Thomas Schneider6, Markus Perbandt3,4, Christian Betzel3,4,5, Henry N. Chapman1,2,4, Michael Heymann1,7 1Center for Free Electron Laser Science, DESY, 2Department of Physics, University of Hamburg, 3Institute for Biochemistry and Molecular Biology, Laboratory for Structural Biology of Infection and Inflammation, University of Hamburg, 4The Hamburg Center for Ultrafast Imaging, University of Hamburg, 5Integrated Biology Infrastructure Life-Science Facility at the European XFEL (XBI), 6European Molecular Biology Laboratory, EMBL c/o DESY, 7Department of Cellular and Molecular Biophysics, Max Planck Institute of Biochemistry JoVE 57133 Chemistry
Groeiende eiwit kristallen met verschillende afmetingen, met behulp van geautomatiseerde kristallisatie in combinatie met In Situ Dynamische lichtverstrooiing Daniela Baitan1,2, Robin Schubert2,3, Arne Meyer1, Karsten Dierks1, Markus Perbandt2,3, Christian Betzel2,3 1Xtal Concepts GmbH, 2Institute for Biochemistry and Molecular Biology, Laboratory for Structural Biology of Infection and Inflammation c/o DESY, University of Hamburg, 3The Hamburg Center for Ultrafast Imaging, University of Hamburg JoVE 57070 Biochemistry
Microfluidic Chips voor In Situ Crystal röntgendiffractie en In Situ Dynamische lichtverstrooiing voor seriële kristallografie Yannig Gicquel*1,2, Robin Schubert*3,4,5, Svetlana Kapis3, Gleb Bourenkov6, Thomas Schneider6, Markus Perbandt3,4, Christian Betzel3,4,5, Henry N. Chapman1,2,4, Michael Heymann1,7 1Center for Free Electron Laser Science, DESY, 2Department of Physics, University of Hamburg, 3Institute for Biochemistry and Molecular Biology, Laboratory for Structural Biology of Infection and Inflammation, University of Hamburg, 4The Hamburg Center for Ultrafast Imaging, University of Hamburg, 5Integrated Biology Infrastructure Life-Science Facility at the European XFEL (XBI), 6European Molecular Biology Laboratory, EMBL c/o DESY, 7Department of Cellular and Molecular Biophysics, Max Planck Institute of Biochemistry JoVE 57133 Chemistry
