Christine Beeton

Publications

• KCa1.1 Potassium Channels Regulate Key Proinflammatory and Invasive Properties of Fibroblast-like Synoviocytes in Rheumatoid Arthritis
  The Journal of Biological Chemistry. Feb, 2012  |   Pubmed ID: 22074915
• Development of a Sea Anemone Toxin As an Immunomodulator for Therapy of Autoimmune Diseases
  Toxicon : Official Journal of the International Society on Toxinology. Aug, 2011  |   Pubmed ID: 21867724
• Analogs of the Sea Anemone Potassium Channel Blocker ShK for the Treatment of Autoimmune Diseases
  Inflammation & Allergy Drug Targets. Oct, 2011  |   Pubmed ID: 21824083
• Genetics and the Environment Converge to Dysregulate N-glycosylation in Multiple Sclerosis
  Nature Communications. 2011  |   Pubmed ID: 21629267
• Imaging of Effector Memory T Cells During a Delayed-type Hypersensitivity Reaction and Suppression by Kv1.3 Channel Block
  Immunity. Oct, 2008  |   Pubmed ID: 18835197
• The D-diastereomer of ShK Toxin Selectively Blocks Voltage-gated K+ Channels and Inhibits T Lymphocyte Proliferation
  The Journal of Biological Chemistry. Jan, 2008  |   Pubmed ID: 17984097
• Discovery on Target 2007--CHI's Fifth Annual Conference. Ion Channels
  IDrugs : the Investigational Drugs Journal. Dec, 2007  |   Pubmed ID: 18041678
• Kv1.3 Channels Are a Therapeutic Target for T Cell-mediated Autoimmune Diseases
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006  |   Pubmed ID: 17088564
• Potassium Channels, Memory T Cells, and Multiple Sclerosis
  The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. Dec, 2005  |   Pubmed ID: 16282596
• The Impact of the Fourth Disulfide Bridge in Scorpion Toxins of the Alpha-KTx6 Subfamily
  Proteins. Dec, 2005  |   Pubmed ID: 16247791
• The Voltage-gated Potassium Channel Kv1.3 is Highly Expressed on Inflammatory Infiltrates in Multiple Sclerosis Brain
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2005  |   Pubmed ID: 16043714
• Targeting Effector Memory T Cells with a Selective Peptide Inhibitor of Kv1.3 Channels for Therapy of Autoimmune Diseases
  Molecular Pharmacology. Apr, 2005  |   Pubmed ID: 15665253
• Evidence for Domain-specific Recognition of SK and Kv Channels by MTX and HsTx1 Scorpion Toxins
  The Journal of Biological Chemistry. Dec, 2004  |   Pubmed ID: 15498765
• Kv1.3-blocking 5-phenylalkoxypsoralens: a New Class of Immunomodulators
  Molecular Pharmacology. Jun, 2004  |   Pubmed ID: 15155830
• K+ Channels As Targets for Specific Immunomodulation
  Trends in Pharmacological Sciences. May, 2004  |   Pubmed ID: 15120495
• Potassium Channels As Therapeutic Targets for Autoimmune Disorders
  Current Opinion in Drug Discovery & Development. Sep, 2003  |   Pubmed ID: 14579513
• The Voltage-gated Kv1.3 K(+) Channel in Effector Memory T Cells As New Target for MS
  The Journal of Clinical Investigation. Jun, 2003  |   Pubmed ID: 12782673
• Myelin Basic Protein-reactive T Cells Induce Conduction Failure in Vivo but Not in Vitro
  Neuroreport. Mar, 2003  |   Pubmed ID: 12634475
• A Novel Fluorescent Toxin to Detect and Investigate Kv1.3 Channel Up-regulation in Chronically Activated T Lymphocytes
  The Journal of Biological Chemistry. Mar, 2003  |   Pubmed ID: 12511563