Christoph E. Hagemeyer

Publications

• Boronate-Phenolic Network Capsules with Dual Response to Acidic PH and Cis-Diols
  Advanced Healthcare Materials. Jun, 2015  |   Pubmed ID: 26088356
• A Versatile Approach for the Site-Specific Modification of Recombinant Antibodies Using a Combination of Enzyme-Mediated Bioconjugation and Click Chemistry
  Angewandte Chemie (International Ed. in English). Jun, 2015  |   Pubmed ID: 25962581
• Engineering Poly(ethylene Glycol) Particles for Improved Biodistribution
  ACS Nano. Feb, 2015  |   Pubmed ID: 25712853
• Targeted Antithrombotic Protein Micelles
  Angewandte Chemie (International Ed. in English). Jan, 2015  |   Pubmed ID: 25504546
• Particle Generation, Functionalization and Sortase A-mediated Modification with Targeting of Single-chain Antibodies for Diagnostic and Therapeutic Use
  Nature Protocols. Jan, 2015  |   Pubmed ID: 25502886
• Single-chain Antibody Conjugated to a Cage Amine Chelator and Labeled with Positron-emitting Copper-64 for Diagnostic Imaging of Activated Platelets
  Molecular Pharmaceutics. Aug, 2014  |   Pubmed ID: 24999533
• Enzyme-mediated Site-specific Bioconjugation of Metal Complexes to Proteins: Sortase-mediated Coupling of Copper-64 to a Single-chain Antibody
  Angewandte Chemie (International Ed. in English). Jun, 2014  |   Pubmed ID: 24777818
• Engineering Multifunctional Capsules Through the Assembly of Metal-phenolic Networks
  Angewandte Chemie (International Ed. in English). May, 2014  |   Pubmed ID: 24700671
• Towards Effective and Safe Thrombolysis and Thromboprophylaxis: Preclinical Testing of a Novel Antibody-targeted Recombinant Plasminogen Activator Directed Against Activated Platelets
  Circulation Research. Mar, 2014  |   Pubmed ID: 24508759
• Detection of Activated Platelets in a Mouse Model of Carotid Artery Thrombosis with 18 F-labeled Single-chain Antibodies
  Nuclear Medicine and Biology. Mar, 2014  |   Pubmed ID: 24440583
• Delayed Targeting of CD39 to Activated Platelet GPIIb/IIIa Via a Single-chain Antibody: Breaking the Link Between Antithrombotic Potency and Bleeding?
  Blood. Apr, 2013  |   Pubmed ID: 23380744
• Enzymatic Antibody Tagging: Toward a Universal Biocompatible Targeting Tool
  Trends in Cardiovascular Medicine. May, 2012  |   Pubmed ID: 22889584
• Bio-Click Chemistry: Enzymatic Functionalization of PEGylated Capsules for Targeting Applications
  Angewandte Chemie (International Ed. in English). Jul, 2012  |   Pubmed ID: 22744941
• Novel Single-chain Antibody-targeted Microbubbles for Molecular Ultrasound Imaging of Thrombosis: Validation of a Unique Noninvasive Method for Rapid and Sensitive Detection of Thrombi and Monitoring of Success or Failure of Thrombolysis in Mice
  Circulation. Jun, 2012  |   Pubmed ID: 22647975
• An Activation-specific Platelet Inhibitor That Can Be Turned On/off by Medically Used Hypothermia
  Arteriosclerosis, Thrombosis, and Vascular Biology. Sep, 2011  |   Pubmed ID: 21659646
• GPVI and GPIbα Mediate Staphylococcal Superantigen-like Protein 5 (SSL5) Induced Platelet Activation and Direct Toward Glycans As Potential Inhibitors
  PloS One. 2011  |   Pubmed ID: 21552524
• Activated Platelets in Carotid Artery Thrombosis in Mice Can Be Selectively Targeted with a Radiolabeled Single-chain Antibody
  PloS One. 2011  |   Pubmed ID: 21479193
• MRI of Inducible P-selectin Expression in Human Activated Platelets Involved in the Early Stages of Atherosclerosis
  NMR in Biomedicine. May, 2011  |   Pubmed ID: 21192086
• Targeting the Platelet Integrin GPIIb/IIIa
  Current Pharmaceutical Design. 2010  |   Pubmed ID: 21247395
• Genetic Transfer of Fusion Proteins Effectively Inhibits VCAM-1-mediated Cell Adhesion and Transmigration Via Inhibition of Cytoskeletal Anchorage
  Journal of Cellular and Molecular Medicine. Jan, 2010  |   Pubmed ID: 20414973
• 7-Benzyloxyresorufin-O-dealkylase Activity As a Marker for Measuring Cytochrome P450 CYP3A Induction in Mouse Liver
  Analytical Biochemistry. Mar, 2010  |   Pubmed ID: 19903449
• Ex-vivo Thrombolytic Gene Therapy for Vein Graft Patency: the Frontier for Development of Selective, Localised Therapeutic Approaches
  Thrombosis and Haemostasis. Jul, 2009  |   Pubmed ID: 19572059
• Dissociation of Pentameric to Monomeric C-reactive Protein on Activated Platelets Localizes Inflammation to Atherosclerotic Plaques
  Circulation Research. Jul, 2009  |   Pubmed ID: 19520972
• Single-chain Antibodies As Diagnostic Tools and Therapeutic Agents
  Thrombosis and Haemostasis. Jun, 2009  |   Pubmed ID: 19492141
• Single-chain Antibodies As New Antithrombotic Drugs
  Seminars in Thrombosis and Hemostasis. Mar, 2007  |   Pubmed ID: 17340468
• Targeting Ligand-induced Binding Sites on GPIIb/IIIa Via Single-chain Antibody Allows Effective Anticoagulation Without Bleeding Time Prolongation
  Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2007  |   Pubmed ID: 17322097
• A Mechanistic Model for Paradoxical Platelet Activation by Ligand-mimetic AlphaIIb Beta3 (GPIIb/IIIa) Antagonists
  Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2007  |   Pubmed ID: 17170374
• Conformation-specific Blockade of the Integrin GPIIb/IIIa: a Novel Antiplatelet Strategy That Selectively Targets Activated Platelets
  Circulation Research. Jul, 2006  |   Pubmed ID: 16778135
• Fibrin-targeted Direct Factor Xa Inhibition: Construction and Characterization of a Recombinant Factor Xa Inhibitor Composed of an Anti-fibrin Single-chain Antibody and Tick Anticoagulant Peptide
  Thrombosis and Haemostasis. Jul, 2004  |   Pubmed ID: 15213844
• Synaptic Vesicle Protein Synaptoporin is Differently Expressed by Subpopulations of Mouse Hippocampal Neurons
  The Journal of Comparative Neurology. Oct, 2002  |   Pubmed ID: 12271488