Christoph Dehio Focal Area Infection Biology, Biozentrum University of Basel Biography Publications Institution JoVE Articles Christoph Dehio has not added a biography. If you are Christoph Dehio and would like to personalize this page please email our Author Liaison for assistance. Publications Biological Diversity and Molecular Plasticity of FIC Domain Proteins Annual Review of Microbiology. Jul, 2016 | Pubmed ID: 27482742 Intrinsic Regulation of FIC-domain AMP-transferases by Oligomerization and Automodification Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26787847 Autophagy Proteins Promote Repair of Endosomal Membranes Damaged by the Salmonella Type Three Secretion System 1 Cell Host & Microbe. Nov, 2015 | Pubmed ID: 26567507 Erratum To: GespeR: a Statistical Model for Deconvoluting Off-target-confounded RNA Interference Screens Genome Biology. 2015 | Pubmed ID: 26490954 GespeR: a Statistical Model for Deconvoluting Off-target-confounded RNA Interference Screens Genome Biology. 2015 | Pubmed ID: 26445817 Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology Cell Reports. Sep, 2015 | Pubmed ID: 26299961 Genome-Wide SiRNA Screen Identifies Complementary Signaling Pathways Involved in Listeria Infection and Reveals Different Actin Nucleation Mechanisms During Listeria Cell Invasion and Actin Comet Tail Formation MBio. 2015 | Pubmed ID: 25991686 NEMix: Single-cell Nested Effects Models for Probabilistic Pathway Stimulation PLoS Computational Biology. Apr, 2015 | Pubmed ID: 25879530 New Insights into the Role of Bartonella Effector Proteins in Pathogenesis Current Opinion in Microbiology. Feb, 2015 | Pubmed ID: 25461577 Simultaneous Analysis of Large-scale RNAi Screens for Pathogen Entry BMC Genomics. 2014 | Pubmed ID: 25534632 Structure of the N-terminal Gyrase B Fragment in Complex with ADP⋅Pi Reveals Rigid-body Motion Induced by ATP Hydrolysis PloS One. 2014 | Pubmed ID: 25202966 A Translocated Effector Required for Bartonella Dissemination from Derma to Blood Safeguards Migratory Host Cells from Damage by Co-translocated Effectors PLoS Pathogens. Jun, 2014 | Pubmed ID: 24945914 An Experimental Strategy for the Identification of AMPylation Targets from Complex Protein Samples Proteomics. May, 2014 | Pubmed ID: 24677795 Specific Inhibition of Diverse Pathogens in Human Cells by Synthetic MicroRNA-like Oligonucleotides Inferred from RNAi Screens Proceedings of the National Academy of Sciences of the United States of America. Mar, 2014 | Pubmed ID: 24616511 Proteome-wide Identification of Predominant Subcellular Protein Localizations in a Bacterial Model Organism Journal of Proteomics. Mar, 2014 | Pubmed ID: 24486812 Multi-scale Gaussian Representation and Outline-learning Based Cell Image Segmentation BMC Bioinformatics. 2013 | Pubmed ID: 24267488 Dual Input Control: Activation of the Bartonella Henselae VirB/D4 Type IV Secretion System by the Stringent Sigma Factor RpoH1 and the BatR/BatS Two-component System Molecular Microbiology. Nov, 2013 | Pubmed ID: 24033511 A Translocation Motif in Relaxase TrwC Specifically Affects Recruitment by Its Conjugative Type IV Secretion System Journal of Bacteriology. Nov, 2013 | Pubmed ID: 23995644 Bartonella and Brucella--weapons and Strategies for Stealth Attack Cold Spring Harbor Perspectives in Medicine. Aug, 2013 | Pubmed ID: 23906880 Directed Shotgun Proteomics Guided by Saturated RNA-seq Identifies a Complete Expressed Prokaryotic Proteome Genome Research. Nov, 2013 | Pubmed ID: 23878158 Conserved Inhibitory Mechanism and Competent ATP Binding Mode for Adenylyltransferases with Fic Fold PloS One. 2013 | Pubmed ID: 23738009 Partial Disruption of Translational and Posttranslational Machinery Reshapes Growth Rates of Bartonella Birtlesii MBio. 2013 | Pubmed ID: 23611908 Systems-level Analysis of Host-pathogen Interaction Using RNA Interference New Biotechnology. Mar, 2013 | Pubmed ID: 23395778 Bartonella Henselae Trimeric Autotransporter Adhesin BadA Expression Interferes with Effector Translocation by the VirB/D4 Type IV Secretion System Cellular Microbiology. May, 2013 | Pubmed ID: 23163798 New Perspectives into Bacterial DNA Transfer to Human Cells Trends in Microbiology. Aug, 2012 | Pubmed ID: 22748513 Bacterial Effector Binds Host Cell Adenylyl Cyclase to Potentiate Gαs-dependent CAMP Production Proceedings of the National Academy of Sciences of the United States of America. Jun, 2012 | Pubmed ID: 22635269 Bartonella Entry Mechanisms into Mammalian Host Cells Cellular Microbiology. Aug, 2012 | Pubmed ID: 22519749 Persistent Intracellular Pathogens FEMS Microbiology Reviews. May, 2012 | Pubmed ID: 22404271 Adenylylation Control by Intra- or Intermolecular Active-site Obstruction in Fic Proteins Nature. Feb, 2012 | Pubmed ID: 22266942 Intruders Below the Radar: Molecular Pathogenesis of Bartonella Spp Clinical Microbiology Reviews. Jan, 2012 | Pubmed ID: 22232371 Persistence of Bartonella Spp. Stealth Pathogens: from Subclinical Infections to Vasoproliferative Tumor Formation FEMS Microbiology Reviews. May, 2012 | Pubmed ID: 22229763 Bartonella Henselae Engages Inside-out and Outside-in Signaling by Integrin β1 and Talin1 During Invasome-mediated Bacterial Uptake Journal of Cell Science. Nov, 2011 | Pubmed ID: 22045736 BID-F1 and BID-F2 Domains of Bartonella Henselae Effector Protein BepF Trigger Together with BepC the Formation of Invasome Structures PloS One. 2011 | Pubmed ID: 22043280 Transfer of R388 Derivatives by a Pathogenesis-associated Type IV Secretion System into Both Bacteria and Human Cells Journal of Bacteriology. Nov, 2011 | Pubmed ID: 21908662 Conjugative DNA Transfer into Human Cells by the VirB/VirD4 Type IV Secretion System of the Bacterial Pathogen Bartonella Henselae Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011 | Pubmed ID: 21844337 Parallel Evolution of a Type IV Secretion System in Radiating Lineages of the Host-restricted Bacterial Pathogen Bartonella PLoS Genetics. 2011 | Pubmed ID: 21347280 Fic Domain-catalyzed Adenylylation: Insight Provided by the Structural Analysis of the Type IV Secretion System Effector BepA Protein Science : a Publication of the Protein Society. Mar, 2011 | Pubmed ID: 21213248 The Bartonella Henselae VirB/Bep System Interferes with Vascular Endothelial Growth Factor (VEGF) Signalling in Human Vascular Endothelial Cells Cellular Microbiology. Mar, 2011 | Pubmed ID: 21044238 Combined Action of the Type IV Secretion Effector Proteins BepC and BepF Promotes Invasome Formation of Bartonella Henselae on Endothelial and Epithelial Cells Cellular Microbiology. Feb, 2011 | Pubmed ID: 20964799 The Trw Type IV Secretion System of Bartonella Mediates Host-specific Adhesion to Erythrocytes PLoS Pathogens. 2010 | Pubmed ID: 20548954 The BatR/BatS Two-component Regulatory System Controls the Adaptive Response of Bartonella Henselae During Human Endothelial Cell Infection Journal of Bacteriology. Jul, 2010 | Pubmed ID: 20418395 Functional Dissection of the Conjugative Coupling Protein TrwB Journal of Bacteriology. Jun, 2010 | Pubmed ID: 20363945 Bacterial Type IV Secretion Systems in Human Disease Molecular Microbiology. Jul, 2009 | Pubmed ID: 19508287 Host Cell Interactome of Tyrosine-phosphorylated Bacterial Proteins Cell Host & Microbe. Apr, 2009 | Pubmed ID: 19380118 A Translocated Protein of Bartonella Henselae Interferes with Endocytic Uptake of Individual Bacteria and Triggers Uptake of Large Bacterial Aggregates Via the Invasome Cellular Microbiology. Jun, 2009 | Pubmed ID: 19302579 Ecological Fitness and Strategies of Adaptation of Bartonella Species to Their Hosts and Vectors Veterinary Research. Mar-Apr, 2009 | Pubmed ID: 19284965 Bartonella Henselae: Subversion of Vascular Endothelial Cell Functions by Translocated Bacterial Effector Proteins The International Journal of Biochemistry & Cell Biology. Mar, 2009 | Pubmed ID: 19010441 Infection-associated Type IV Secretion Systems of Bartonella and Their Diverse Roles in Host Cell Interaction Cellular Microbiology. Aug, 2008 | Pubmed ID: 18489724 Genomic Analysis of Bartonella Identifies Type IV Secretion Systems As Host Adaptability Factors Nature Genetics. Dec, 2007 | Pubmed ID: 18037886 A Translocated Bacterial Protein Protects Vascular Endothelial Cells from Apoptosis PLoS Pathogens. Nov, 2006 | Pubmed ID: 17121462 Characterization of Genes Involved in Long-term Bacteremia in Mice by Bartonella Birtlesii Annals of the New York Academy of Sciences. Dec, 2005 | Pubmed ID: 16481533 Functional Interactions Between Type IV Secretion Systems Involved in DNA Transfer and Virulence Microbiology (Reading, England). Nov, 2005 | Pubmed ID: 16272374 Signature-tagged Mutagenesis: Technical Advances in a Negative Selection Method for Virulence Gene Identification Current Opinion in Microbiology. Oct, 2005 | Pubmed ID: 16126452 Characterization of the Genome Composition of Bartonella Koehlerae by Microarray Comparative Genomic Hybridization Profiling Journal of Bacteriology. Sep, 2005 | Pubmed ID: 16109957 Bartonella-host-cell Interactions and Vascular Tumour Formation Nature Reviews. Microbiology. Aug, 2005 | Pubmed ID: 16064054 VEGF-A and PlGF-1 Stimulate Chemotactic Migration of Human Mesenchymal Progenitor Cells Biochemical and Biophysical Research Communications. Aug, 2005 | Pubmed ID: 16005848 Virulence-associated Type IV Secretion Systems of Bartonella Trends in Microbiology. Jul, 2005 | Pubmed ID: 15935675 A Bipartite Signal Mediates the Transfer of Type IV Secretion Substrates of Bartonella Henselae into Human Cells Proceedings of the National Academy of Sciences of the United States of America. Jan, 2005 | Pubmed ID: 15642951 Isolation of Bartonella Schoenbuchensis from Lipoptena Cervi, a Blood-sucking Arthropod Causing Deer Ked Dermatitis Journal of Clinical Microbiology. Nov, 2004 | Pubmed ID: 15528732 Molecular and Cellular Basis of Bartonella Pathogenesis Annual Review of Microbiology. 2004 | Pubmed ID: 15487942 Proteomic Analysis of the Sarcosine-insoluble Outer Membrane Fraction of the Bacterial Pathogen Bartonella Henselae Proteomics. Oct, 2004 | Pubmed ID: 15378747 Genome-wide Analysis of Transcriptional Hierarchy and Feedback Regulation in the Flagellar System of Helicobacter Pylori Molecular Microbiology. May, 2004 | Pubmed ID: 15130117 The VirB Type IV Secretion System of Bartonella Henselae Mediates Invasion, Proinflammatory Activation and Antiapoptotic Protection of Endothelial Cells Molecular Microbiology. Apr, 2004 | Pubmed ID: 15049812 Coordinated Activation of VEGFR-1 and VEGFR-2 is a Potent Arteriogenic Stimulus Leading to Enhancement of Regional Perfusion Cardiovascular Research. Mar, 2004 | Pubmed ID: 14985076 Structure and Biological Activity of the Short-chain Lipopolysaccharide from Bartonella Henselae ATCC 49882T The Journal of Biological Chemistry. May, 2004 | Pubmed ID: 14766898 An Engineered Heparin-binding Form of VEGF-E (hbVEGF-E). Biological Effects in Vitro and Mobilizatiion of Precursor Cells Angiogenesis. 2003 | Pubmed ID: 15041796 A Bacterial Conjugation Machinery Recruited for Pathogenesis Molecular Microbiology. Sep, 2003 | Pubmed ID: 12940985 Role of PlGF in the Intra- and Intermolecular Cross Talk Between the VEGF Receptors Flt1 and Flk1 Nature Medicine. Jul, 2003 | Pubmed ID: 12796773 Recent Progress in Understanding Bartonella-induced Vascular Proliferation Current Opinion in Microbiology. Feb, 2003 | Pubmed ID: 12615221 Characterization of the Cryptic Plasmid PBGR1 from Bartonella Grahamii and Construction of a Versatile Escherichia Coli-Bartonella Spp. Shuttle Cloning Vector Plasmid. Jan, 2003 | Pubmed ID: 12584000 The VirB/VirD4 Type IV Secretion System of Bartonella is Essential for Establishing Intraerythrocytic Infection Molecular Microbiology. Nov, 2002 | Pubmed ID: 12421311 Bartonella Bovis Bermond Et Al. Sp. Nov. and Bartonella Capreoli Sp. Nov., Isolated from European Ruminants International Journal of Systematic and Evolutionary Microbiology. Mar, 2002 | Pubmed ID: 11931146 Bacterial Persistence Within Erythrocytes: a Unique Pathogenic Strategy of Bartonella Spp International Journal of Medical Microbiology : IJMM. Feb, 2002 | Pubmed ID: 11890558 Os ensaios baseados em microscopia para high-throughput screening de Fatores Hospedeiros Envolvidos na Alain Casanova*1, Shyan H. Low*1, Mario Emmenlauer*1,4, Raquel Conde-Alvarez*1,3, Suzana P. Salcedo2, Jean-Pierre Gorvel2, Christoph Dehio1 1Focal Area Infection Biology, Biozentrum, University of Basel, 2Centre d’Immunologie de Marseille-Luminy, Université de la Méditérannée UM2, INSERM U1104 CNRS UM7280, 3Departmento de Microbiologìa and Instituto de Salud Tropical, Universidad de Navarra, 4BioDataAnalysis GmbH Immunology and Infection Imagiologia inLC Secreção para investigar infecção celular pelo patógeno bacteriano Andreas Kühbacher1,2,3, Edith Gouin1,2,3, Jason Mercer4, Mario Emmenlauer5, Christoph Dehio5, Pascale Cossart1,2,3, Javier Pizarro-Cerdá1,2,3 1Unité des Interactions Bactéries Cellules, Pasteur Institute, 2INSERM U604, 3Institut National de la Recherche Agronomique (INRA), USC2020, 4Institute of Biochemistry, ETH Zürich, 5Focal Area Infection Biology, Biozentrum, University of Basel JoVE 51043 Immunology and Infection
Os ensaios baseados em microscopia para high-throughput screening de Fatores Hospedeiros Envolvidos na Alain Casanova*1, Shyan H. Low*1, Mario Emmenlauer*1,4, Raquel Conde-Alvarez*1,3, Suzana P. Salcedo2, Jean-Pierre Gorvel2, Christoph Dehio1 1Focal Area Infection Biology, Biozentrum, University of Basel, 2Centre d’Immunologie de Marseille-Luminy, Université de la Méditérannée UM2, INSERM U1104 CNRS UM7280, 3Departmento de Microbiologìa and Instituto de Salud Tropical, Universidad de Navarra, 4BioDataAnalysis GmbH Immunology and Infection
Imagiologia inLC Secreção para investigar infecção celular pelo patógeno bacteriano Andreas Kühbacher1,2,3, Edith Gouin1,2,3, Jason Mercer4, Mario Emmenlauer5, Christoph Dehio5, Pascale Cossart1,2,3, Javier Pizarro-Cerdá1,2,3 1Unité des Interactions Bactéries Cellules, Pasteur Institute, 2INSERM U604, 3Institut National de la Recherche Agronomique (INRA), USC2020, 4Institute of Biochemistry, ETH Zürich, 5Focal Area Infection Biology, Biozentrum, University of Basel JoVE 51043 Immunology and Infection
