Christoph Winkler

Publications

• A Vertebrate Specific and Essential Role for Sp7/osterix in Osteogenesis Revealed by Gene Knock-out in the Teleost Medaka
  Development (Cambridge, England). Dec, 2016  |   Pubmed ID: 27993982
• Transcriptional Enhancement of Smn Levels in Motoneurons is Crucial for Proper Axon Morphology in Zebrafish
  Scientific Reports. Jun, 2016  |   Pubmed ID: 27273160
• Trametes Versicolor Carboxylate Reductase Uncovered
  Monatshefte Fur Chemie. 2016  |   Pubmed ID: 27069283
• Live Imaging of Osteoclast Inhibition by Bisphosphonates in a Medaka Osteoporosis Model
  Disease Models & Mechanisms. Feb, 2016  |   Pubmed ID: 26704995
• An Adult Osteopetrosis Model in Medaka Reveals the Importance of Osteoclast Function for Bone Remodeling in Teleost Fish
  Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP. Dec, 2015  |   Pubmed ID: 26334373
• The Wnt Co-Receptor Lrp5 Is Required for Cranial Neural Crest Cell Migration in Zebrafish
  PloS One. 2015  |   Pubmed ID: 26121341
• The Flatness of Lamellipodia Explained by the Interaction Between Actin Dynamics and Membrane Deformation
  Journal of Theoretical Biology. Sep, 2015  |   Pubmed ID: 26002996
• A Multifunctional Mutagenesis System for Analysis of Gene Function in Zebrafish
  G3 (Bethesda, Md.). Apr, 2015  |   Pubmed ID: 25840430
• Effect of Rubber Flooring on Dairy Cattle Stepping Behavior and Muscle Activity
  Journal of Dairy Science. Apr, 2015  |   Pubmed ID: 25648801
• Dmrt5 Controls Corticotrope and Gonadotrope Differentiation in the Zebrafish Pituitary
  Molecular Endocrinology (Baltimore, Md.). Feb, 2015  |   Pubmed ID: 25489906
• Nitrile As Activating Group in the Asymmetric Bioreduction of β-Cyanoacrylic Acids Catalyzed by Ene-Reductases
  Advanced Synthesis & Catalysis. May, 2014  |   Pubmed ID: 26190962
• Identification of a PRPF4 Loss-of-function Variant That Abrogates U4/U6.U5 Tri-snRNP Integration and is Associated with Retinitis Pigmentosa
  PloS One. 2014  |   Pubmed ID: 25383878
• Identification of Promiscuous Ene-reductase Activity by Mining Structural Databases Using Active Site Constellations
  Nature Communications. Jun, 2014  |   Pubmed ID: 24954722
• Bioreduction and Disproportionation of Cyclohex-2-enone Catalyzed by Ene-reductase OYE-1 in 'micro-aqueous' Organic Solvents
  Biotechnology Letters. Jun, 2014  |   Pubmed ID: 24563324
• Electron Tomography and Simulation of Baculovirus Actin Comet Tails Support a Tethered Filament Model of Pathogen Propulsion
  PLoS Biology. Jan, 2014  |   Pubmed ID: 24453943
• Osterix/Sp7 Regulates Biomineralization of Otoliths and Bone in Medaka (Oryzias Latipes)
  Matrix Biology : Journal of the International Society for Matrix Biology. Feb, 2014  |   Pubmed ID: 24407212
• NAD(P)H-independent Asymmetric C=C Bond Reduction Catalyzed by Ene Reductases by Using Artificial Co-substrates As the Hydrogen Donor
  Chemistry (Weinheim an Der Bergstrasse, Germany). Jan, 2014  |   Pubmed ID: 24382795
• SMN Deficiency Alters Nrxn2 Expression and Splicing in Zebrafish and Mouse Models of Spinal Muscular Atrophy
  Human Molecular Genetics. Apr, 2014  |   Pubmed ID: 24218366
• Arp2/3 Complex is Essential for Actin Network Treadmilling As Well As for Targeting of Capping Protein and Cofilin
  Molecular Biology of the Cell. Sep, 2013  |   Pubmed ID: 23885122
• Overcoming Co-product Inhibition in the Nicotinamide Independent Asymmetric Bioreduction of Activated C=C-bonds Using Flavin-dependent Ene-reductases
  Biotechnology and Bioengineering. Dec, 2013  |   Pubmed ID: 23794404
• A Col10a1:nlGFP Transgenic Line Displays Putative Osteoblast Precursors at the Medaka Notochordal Sheath Prior to Mineralization
  Developmental Biology. Sep, 2013  |   Pubmed ID: 23769979
• Two Isoforms of Sister-Of-Mammalian Grainyhead Have Opposing Functions in Endothelial Cells and in Vivo
  Arteriosclerosis, Thrombosis, and Vascular Biology. Jul, 2013  |   Pubmed ID: 23685552
• Anaplastic Lymphoma Kinase is Required for Neurogenesis in the Developing Central Nervous System of Zebrafish
  PloS One. 2013  |   Pubmed ID: 23667670
• Zebrafish Hoxd4a Acts Upstream of Meis1.1 to Direct Vasculogenesis, Angiogenesis and Hematopoiesis
  PloS One. 2013  |   Pubmed ID: 23554940
• Structure-function Analysis of Full-length Midkine Reveals Novel Residues Important for Heparin-binding and Zebrafish Embryogenesis
  The Biochemical Journal. Feb, 2013  |   Pubmed ID: 23418741
• Chemoenzymatic Asymmetric Synthesis of Pregabalin Precursors Via Asymmetric Bioreduction of β-cyanoacrylate Esters Using Ene-reductases
  The Journal of Organic Chemistry. Feb, 2013  |   Pubmed ID: 23316696
• Dynamic Microtubules at the Vegetal Cortex Predict the Embryonic Axis in Zebrafish
  Development (Cambridge, England). Oct, 2012  |   Pubmed ID: 22949618
• The 1D4 Antibody Labels Outer Segments of Long Double Cone but Not Rod Photoreceptors in Zebrafish
  Investigative Ophthalmology & Visual Science. Jul, 2012  |   Pubmed ID: 22743318
• A Substrate-driven Approach to Determine Reactivities of α,β-unsaturated Carboxylic Esters Towards Asymmetric Bioreduction
  Chemistry (Weinheim an Der Bergstrasse, Germany). Aug, 2012  |   Pubmed ID: 22736443
• Asymmetric Bioreduction of Activated Alkenes to Industrially Relevant Optically Active Compounds
  Journal of Biotechnology. Dec, 2012  |   Pubmed ID: 22498437
• Actin Branching in the Initiation and Maintenance of Lamellipodia
  Journal of Cell Science. Jun, 2012  |   Pubmed ID: 22431015
• Actin Filament Tracking in Electron Tomograms of Negatively Stained Lamellipodia Using the Localized Radon Transform
  Journal of Structural Biology. Apr, 2012  |   Pubmed ID: 22387240
• Conditional Ablation of Osteoblasts in Medaka
  Developmental Biology. Apr, 2012  |   Pubmed ID: 22326228
• The Popeye Domain Containing 2 (popdc2) Gene in Zebrafish is Required for Heart and Skeletal Muscle Development
  Developmental Biology. Mar, 2012  |   Pubmed ID: 22290329
• Rankl-induced Osteoclastogenesis Leads to Loss of Mineralization in a Medaka Osteoporosis Model
  Development (Cambridge, England). Jan, 2012  |   Pubmed ID: 22096076
• Mutant Prpf31 Causes Pre-mRNA Splicing Defects and Rod Photoreceptor Cell Degeneration in a Zebrafish Model for Retinitis Pigmentosa
  Molecular Neurodegeneration. Jul, 2011  |   Pubmed ID: 21801444
• Asymmetric Bioreduction of Alkenes Using Ene-reductases YersER and KYE1 and Effects of Organic Solvents
  Organic Letters. May, 2011  |   Pubmed ID: 21510626
• Combined in Vivo Imaging and Omics Approaches Reveal Metabolism of Icaritin and Its Glycosides in Zebrafish Larvae
  Molecular BioSystems. Jul, 2011  |   Pubmed ID: 21445457
• Systemic Splicing Factor Deficiency Causes Tissue-specific Defects: a Zebrafish Model for Retinitis Pigmentosa
  Human Molecular Genetics. Jan, 2011  |   Pubmed ID: 21051334
• Bioreduction of Alpha-methylcinnamaldehyde Derivatives: Chemo-enzymatic Asymmetric Synthesis of Lilial and Helional
  Dalton Transactions (Cambridge, England : 2003). Sep, 2010  |   Pubmed ID: 20461254
• Tgfbeta3 Regulation of Chondrogenesis and Osteogenesis in Zebrafish is Mediated Through Formation and Survival of a Subpopulation of the Cranial Neural Crest
  Mechanisms of Development. Jul-Aug, 2010  |   Pubmed ID: 20406684
• Accessibility of Host Cell Lineages to Medaka Stem Cells Depends on Genetic Background and Irradiation of Recipient Embryos
  Cellular and Molecular Life Sciences : CMLS. Apr, 2010  |   Pubmed ID: 20238480
• The Heterogeneous Nuclear Ribonucleoprotein-R is Necessary for Axonal Beta-actin MRNA Translocation in Spinal Motor Neurons
  Human Molecular Genetics. May, 2010  |   Pubmed ID: 20167579
• Phylogenetic and Evolutionary Relationships and Developmental Expression Patterns of the Zebrafish Twist Gene Family
  Development Genes and Evolution. Jun, 2009  |   Pubmed ID: 19565261
• Osterix-mCherry Transgenic Medaka for in Vivo Imaging of Bone Formation
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Jan, 2009  |   Pubmed ID: 19097055
• Genetic Analysis of Somite Formation in Laboratory Fish Models
  Advances in Experimental Medicine and Biology. 2008  |   Pubmed ID: 21038770
• Retinoic Acid and Cyp26b1 Are Critical Regulators of Osteogenesis in the Axial Skeleton
  Development (Cambridge, England). Nov, 2008  |   Pubmed ID: 18927155
• An Asymmetric Distribution of Positrons in the Galactic Disk Revealed by Gamma-rays
  Nature. Jan, 2008  |   Pubmed ID: 18185581
• Midkine-b Regulates Cell Specification at the Neural Plate Border in Zebrafish
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Jan, 2008  |   Pubmed ID: 18058915
• Influence of Verapamil on Tachycardia-induced Alterations of PP1 and PP2A in Rabbit Atrium
  Experimental and Clinical Cardiology. 2007  |   Pubmed ID: 18651001
• Effect of Verapamil on Tachycardia-induced Early Cellular Electrical Remodeling in Rabbit Atrium
  Naunyn-Schmiedeberg's Archives of Pharmacology. Dec, 2007  |   Pubmed ID: 17874072
• Inhibition of Primordial Germ Cell Proliferation by the Medaka Male Determining Gene Dmrt I BY
  BMC Developmental Biology. Aug, 2007  |   Pubmed ID: 17760954
• Pituitary-interrenal Interaction in Zebrafish Interrenal Organ Development
  Molecular Endocrinology (Baltimore, Md.). Feb, 2007  |   Pubmed ID: 17082325
• Discontinuous Organization and Specification of the Lateral Floor Plate in Zebrafish
  Developmental Biology. Jan, 2007  |   Pubmed ID: 17045256
• Tissue-specific Expression of Dmrt Genes in Embryos and Adults of the Platyfish Xiphophorus Maculatus
  Zebrafish. 2006  |   Pubmed ID: 18377213
• Structural and Functional Characterization of the Zebrafish Lamin B Receptor
  European Journal of Cell Biology. Aug, 2006  |   Pubmed ID: 16759737
• Dynamic Expression of Sparc Precedes Formation of Skeletal Elements in the Medaka (Oryzias Latipes)
  Gene. May, 2006  |   Pubmed ID: 16545530
• Her1 and Her13.2 Are Jointly Required for Somitic Border Specification Along the Entire Axis of the Fish Embryo
  Developmental Biology. May, 2006  |   Pubmed ID: 16545363
• Comparative Analysis of Her Genes During Fish Somitogenesis Suggests a Mouse/chick-like Mode of Oscillation in Medaka
  Development Genes and Evolution. Jun, 2006  |   Pubmed ID: 16544152
• Radioactive 26Al from Massive Stars in the Galaxy
  Nature. Jan, 2006  |   Pubmed ID: 16397491
• Identification and Comparative Expression Analysis of a Second Wt1 Gene in Zebrafish
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Feb, 2006  |   Pubmed ID: 16292775
• Reduced U SnRNP Assembly Causes Motor Axon Degeneration in an Animal Model for Spinal Muscular Atrophy
  Genes & Development. Oct, 2005  |   Pubmed ID: 16204184
• Medial Floor Plate Formation in Zebrafish Consists of Two Phases and Requires Trunk-derived Midkine-a
  Genes & Development. Apr, 2005  |   Pubmed ID: 15833916
• Hedgehog and Retinoid Signalling Confines Nkx2.2b Expression to the Lateral Floor Plate of the Zebrafish Trunk
  Mechanisms of Development. Jan, 2005  |   Pubmed ID: 15582776
• The Lamina-associated Polypeptide 2 (LAP2) Genes of Zebrafish and Chicken: No LAP2alpha Isoform is Synthesised by Non-mammalian Vertebrates
  European Journal of Cell Biology. Aug, 2004  |   Pubmed ID: 15506564
• Her7 and Hey1, but Not Lunatic Fringe Show Dynamic Expression During Somitogenesis in Medaka (Oryzias Latipes)
  Gene Expression Patterns : GEP. Sep, 2004  |   Pubmed ID: 15261833
• Developmentally Regulated and Non-sex-specific Expression of Autosomal Dmrt Genes in Embryos of the Medaka Fish (Oryzias Latipes)
  Mechanisms of Development. Jul, 2004  |   Pubmed ID: 15210205
• Activation of the Mouse Oct4 Promoter in Medaka Embryonic Stem Cells and Its Use for Ablation of Spontaneous Differentiation
  Mechanisms of Development. Jul, 2004  |   Pubmed ID: 15210197
• Mutations Affecting Retina Development in Medaka
  Mechanisms of Development. Jul, 2004  |   Pubmed ID: 15210178
• Mutations Affecting Somite Formation in the Medaka (Oryzias Latipes)
  Mechanisms of Development. Jul, 2004  |   Pubmed ID: 15210175
• A Systematic Genome-wide Screen for Mutations Affecting Organogenesis in Medaka, Oryzias Latipes
  Mechanisms of Development. Jul, 2004  |   Pubmed ID: 15210174
• Characterization of Hey BHLH Genes in Teleost Fish
  Development Genes and Evolution. Nov, 2003  |   Pubmed ID: 14593478
• Functional Divergence of Two Zebrafish Midkine Growth Factors Following Fish-specific Gene Duplication
  Genome Research. Jun, 2003  |   Pubmed ID: 12743018
• The Lamina-associated Polypeptide 2 (LAP2) Isoforms Beta, Gamma and Omega of Zebrafish: Developmental Expression and Behavior During the Cell Cycle
  Journal of Cell Science. Jun, 2003  |   Pubmed ID: 12734396
• The Pro-opiomelanocortin Gene of the Zebrafish (Danio Rerio)
  Biochemical and Biophysical Research Communications. Apr, 2003  |   Pubmed ID: 12684052
• A Duplicated Copy of DMRT1 in the Sex-determining Region of the Y Chromosome of the Medaka, Oryzias Latipes
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2002  |   Pubmed ID: 12193652