Christophe Combadière Centre d'Immunologie et des Maladies Infectieuses (CIMI), INSERM, U1135, CNRS, ERL 8255 Sorbonne Universités, UPMC Univ Paris 06, CR7 Biography Publications Institution JoVE Articles Christophe Combadière has not added a biography. If you are Christophe Combadière and would like to personalize this page please email our Author Liaison for assistance. Publications Apolipoprotein E Promotes Subretinal Mononuclear Phagocyte Survival and Chronic Inflammation in Age-related Macular Degeneration EMBO Molecular Medicine. 2015 | Pubmed ID: 25604058 Pachymodulin, a New Functional Formyl Peptide Receptor 2 Peptidic Ligand Isolated from Frog Skin Has Janus-like Immunomodulatory Capacities Journal of Medicinal Chemistry. Feb, 2015 | Pubmed ID: 25587631 Stromal Cell-derived CCL2 Drives Neuropathic Pain States Through Myeloid Cell Infiltration in Injured Nerve Brain, Behavior, and Immunity. Mar, 2015 | Pubmed ID: 25449579 CX3CL1, a Chemokine Finely Tuned to Adhesion: Critical Roles of the Stalk Glycosylation and the Membrane Domain Biology Open. 2014 | Pubmed ID: 25395671 In Vivo Imaging Reveals a Pioneer Wave of Monocyte Recruitment into Mouse Skin Wounds PloS One. 2014 | Pubmed ID: 25272047 CCR5 As a Treatment Target in Pulmonary Arterial Hypertension Circulation. Sep, 2014 | Pubmed ID: 24993099 International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the Extended Family of Chemokine Receptors and Introducing a New Nomenclature for Atypical Chemokine Receptors Pharmacological Reviews. 2014 | Pubmed ID: 24218476 CCR2(+) Monocytes Infiltrate Atrophic Lesions in Age-related Macular Disease and Mediate Photoreceptor Degeneration in Experimental Subretinal Inflammation in Cx3cr1 Deficient Mice EMBO Molecular Medicine. Nov, 2013 | Pubmed ID: 24142887 Pharmacological Inhibition of the Chemokine Receptor, CX3CR1, Reduces Atherosclerosis in Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2013 | Pubmed ID: 23887641 CX3CR1 Reduces Ly6Chigh-monocyte Motility Within and Release from the Bone Marrow After Chemotherapy in Mice Blood. Aug, 2013 | Pubmed ID: 23775714 Control of Both Myeloid Cell Infiltration and Angiogenesis by CCR1 Promotes Liver Cancer Metastasis Development in Mice Neoplasia (New York, N.Y.). Jun, 2013 | Pubmed ID: 23730212 Slow CCL2-dependent Translocation of Biopersistent Particles from Muscle to Brain BMC Medicine. 2013 | Pubmed ID: 23557144 Comment on "Ccl2, Cx3cr1 and Ccl2/Cx3cr1 Chemokine Deficiencies Are Not Sufficient to Cause Age-related Retinal Degeneration" by Luhmann Et al. (Exp. Eye Res. 2013; 107: 80.doi: 10.1016) Experimental Eye Research. Jun, 2013 | Pubmed ID: 23402809 CD8+ Tumor-infiltrating T Cells Are Trapped in the Tumor-dendritic Cell Network Neoplasia (New York, N.Y.). Jan, 2013 | Pubmed ID: 23359264 Reduced Il17a Expression Distinguishes a Ly6c(lo)MHCII(hi) Macrophage Population Promoting Wound Healing The Journal of Investigative Dermatology. Mar, 2013 | Pubmed ID: 23235530 Role of Chemokines and Chemokine Receptors in Shaping the Effector Phase of the Antitumor Immune Response Cancer Research. Dec, 2012 | Pubmed ID: 23222302 Neutrophils Transport Antigen from the Dermis to the Bone Marrow, Initiating a Source of Memory CD8+ T Cells Immunity. Nov, 2012 | Pubmed ID: 23142782 The Chemokine Decoy Receptor D6 Prevents Excessive Inflammation and Adverse Ventricular Remodeling After Myocardial Infarction Arteriosclerosis, Thrombosis, and Vascular Biology. Sep, 2012 | Pubmed ID: 22796582 Interleukin-15-dependent NKp46+ Innate Lymphoid Cells Control Intestinal Inflammation by Recruiting Inflammatory Monocytes Immunity. Jul, 2012 | Pubmed ID: 22705105 MFGE8 Does Not Influence Chorio-retinal Homeostasis or Choroidal Neovascularization in Vivo PloS One. 2012 | Pubmed ID: 22438901 Cutting Edge: Protective Effect of CX3CR1+ Dendritic Cells in a Vaccinia Virus Pulmonary Infection Model Journal of Immunology (Baltimore, Md. : 1950). Feb, 2012 | Pubmed ID: 22219332 Chemokine Receptor CCR1 Disruption Limits Renal Damage in a Murine Model of Hemolytic Uremic Syndrome The American Journal of Pathology. Mar, 2012 | Pubmed ID: 22203055 The Chemokine CCL2 Protects Against Methylmercury Neurotoxicity Toxicological Sciences : an Official Journal of the Society of Toxicology. Jan, 2012 | Pubmed ID: 21976372 Identification of the Chemokine CX3CL1 As a New Regulator of Malignant Cell Proliferation in Epithelial Ovarian Cancer PloS One. 2011 | Pubmed ID: 21750716 Interleukin-1β Inhibition Prevents Choroidal Neovascularization and Does Not Exacerbate Photoreceptor Degeneration The American Journal of Pathology. May, 2011 | Pubmed ID: 21514452 [Role of Chemokines in the Development of Age-related Macular Degeneration] Biologie Aujourd'hui. 2010 | Pubmed ID: 21215248 [Atherosclerosis : on the Trail of Chemokines] Biologie Aujourd'hui. 2010 | Pubmed ID: 21215245 CCL2/CCR2 and CX3CL1/CX3CR1 Chemokine Axes and Their Possible Involvement in Age-related Macular Degeneration Journal of Neuroinflammation. 2010 | Pubmed ID: 21126357 Subtle Conformational Changes Between CX3CR1 Genetic Variants As Revealed by Resonance Energy Transfer Assays FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2010 | Pubmed ID: 20667981 Regulation of Monocyte Subset Systemic Levels by Distinct Chemokine Receptors Controls Post-ischaemic Neovascularization Cardiovascular Research. Oct, 2010 | Pubmed ID: 20501509 TGF-beta Activity Protects Against Inflammatory Aortic Aneurysm Progression and Complications in Angiotensin II-infused Mice The Journal of Clinical Investigation. Feb, 2010 | Pubmed ID: 20101093 Mycobacterium Bovis Bacillus Calmette-Guérin Vaccination Mobilizes Innate Myeloid-derived Suppressor Cells Restraining in Vivo T Cell Priming Via IL-1R-dependent Nitric Oxide Production Journal of Immunology (Baltimore, Md. : 1950). Feb, 2010 | Pubmed ID: 20083674 Opposing Effects of Toll-like Receptor (TLR3) Signaling in Tumors Can Be Therapeutically Uncoupled to Optimize the Anticancer Efficacy of TLR3 Ligands Cancer Research. Jan, 2010 | Pubmed ID: 20068181 Intratumoral Induction of CD103 Triggers Tumor-specific CTL Function and CCR5-dependent T-cell Retention Cancer Research. Aug, 2009 | Pubmed ID: 19638592 An Engineered CX3CR1 Antagonist Endowed with Anti-inflammatory Activity Journal of Leukocyte Biology. Oct, 2009 | Pubmed ID: 19571253 Polymorphism in the Microglial Cell-mobilizing CX3CR1 Gene is Associated with Survival in Patients with Glioblastoma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2008 | Pubmed ID: 19001328 CX3CL1/fractalkine is Released from Apoptotic Lymphocytes to Stimulate Macrophage Chemotaxis Blood. Dec, 2008 | Pubmed ID: 18799722 Functional Adhesiveness of the CX3CL1 Chemokine Requires Its Aggregation. Role of the Transmembrane Domain The Journal of Biological Chemistry. Oct, 2008 | Pubmed ID: 18725411 Role of the Chemokine Receptor CX3CR1 in the Mobilization of Phagocytic Retinal Microglial Cells Journal of Neuroimmunology. Jul, 2008 | Pubmed ID: 18508131 Intra-neural Administration of Fractalkine Attenuates Neuropathic Pain-related Behaviour Journal of Neurochemistry. Jul, 2008 | Pubmed ID: 18410510 [Macular Degeneration: Retinal Microglial Cells Are Guilty] Médecine Sciences : M/S. Apr, 2008 | Pubmed ID: 18405632 Combined Inhibition of CCL2, CX3CR1, and CCR5 Abrogates Ly6C(hi) and Ly6C(lo) Monocytosis and Almost Abolishes Atherosclerosis in Hypercholesterolemic Mice Circulation. Apr, 2008 | Pubmed ID: 18347211 Influence of MDM2 SNP309 Alone or in Combination with the TP53 R72P Polymorphism in Oligodendroglial Tumors Brain Research. Mar, 2008 | Pubmed ID: 18262501 Common CX3CR1 Alleles Are Associated with a Reduced Risk of Headaches Headache. Jul, 2008 | Pubmed ID: 18194290 CX3CR1-dependent Subretinal Microglia Cell Accumulation is Associated with Cardinal Features of Age-related Macular Degeneration The Journal of Clinical Investigation. Oct, 2007 | Pubmed ID: 17909628 Dynamic Imaging of Chemokine-dependent CD8+ T Cell Help for CD8+ T Cell Responses Nature Immunology. Sep, 2007 | Pubmed ID: 17660821 Polymorphisms in 33 Inflammatory Genes and Risk of Myocardial Infarction--a System Genetics Approach Journal of Molecular Medicine (Berlin, Germany). Nov, 2007 | Pubmed ID: 17634906 CX3CR1 Polymorphisms Are Associated with Atopy but Not Asthma in German Children International Archives of Allergy and Immunology. 2007 | Pubmed ID: 17505143 Single CX3CL1-Ig DNA Administration Enhances T Cell Priming in Vivo Vaccine. Jun, 2007 | Pubmed ID: 17493713 Defective Antitumor Responses in CX3CR1-deficient Mice International Journal of Cancer. Journal International Du Cancer. Jul, 2007 | Pubmed ID: 17372897 [Chemokines: a Sophisticated Cell-guidance Network] Médecine Sciences : M/S. Feb, 2007 | Pubmed ID: 17291427 Trapping and Apoptosis of Novel Subsets of Memory T Lymphocytes Expressing CCR6 in the Spleen of HIV-infected Patients Blood. May, 2007 | Pubmed ID: 17197436 Melanoma Susceptibility and Progression: Association Study Between Polymorphisms of the Chemokine (CCL2) and Chemokine Receptors (CX3CR1, CCR5) Journal of Dermatological Science. Apr, 2007 | Pubmed ID: 17169533 Involvement of the Fractalkine Pathway in the Pathogenesis of Childhood Hemolytic Uremic Syndrome Blood. Mar, 2007 | Pubmed ID: 17132725 High Cytotoxic and Specific Migratory Potencies of Senescent CD8+ CD57+ Cells in HIV-infected and Uninfected Individuals Journal of Immunology (Baltimore, Md. : 1950). Oct, 2006 | Pubmed ID: 17015699 In Vivo Cellular Imaging of Lymphocyte Trafficking by MRI: a Tumor Model Approach to Cell-based Anticancer Therapy Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Sep, 2006 | Pubmed ID: 16897768 Role of Bone Marrow-derived CC-chemokine Receptor 5 in the Development of Atherosclerosis of Low-density Lipoprotein Receptor Knockout Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2006 | Pubmed ID: 16763157 Cytokine Polymorphisms Associated with Carotid Intima-media Thickness in Stroke Patients Stroke; a Journal of Cerebral Circulation. Jul, 2006 | Pubmed ID: 16741188 Polymorphisms in Chemokine and Chemokine Receptor Genes and the Development of Coal Workers' Pneumoconiosis Cytokine. Feb, 2006 | Pubmed ID: 16524739 Chemokine Receptor CCR1 Disruption in Bone Marrow Cells Enhances Atherosclerotic Lesion Development and Inflammation in Mice Molecular Medicine (Cambridge, Mass.). Jan-Dec, 2005 | Pubmed ID: 16491201 Impairment in Postischemic Neovascularization in Mice Lacking the CXC Chemokine Receptor 3 Circulation Research. Mar, 2005 | Pubmed ID: 15718500 Adverse Associations Between CX3CR1 Polymorphisms and Risk of Cardiovascular or Cerebrovascular Disease Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2005 | Pubmed ID: 15681302 Intratumoral CC Chemokine Ligand 5 Overexpression Delays Tumor Growth and Increases Tumor Cell Infiltration Journal of Immunology (Baltimore, Md. : 1950). Sep, 2004 | Pubmed ID: 15356122 Antigen Distribution Drives Programmed Antitumor CD8 Cell Migration and Determines Its Efficiency Journal of Immunology (Baltimore, Md. : 1950). Jul, 2004 | Pubmed ID: 15210778 Enhanced Adhesive Capacities of the Naturally Occurring Ile249-Met280 Variant of the Chemokine Receptor CX3CR1 The Journal of Biological Chemistry. May, 2004 | Pubmed ID: 14990582 Roles of CCR2 and CXCR3 in the T Cell-mediated Response Occurring During Lupus Flares Arthritis and Rheumatism. Dec, 2003 | Pubmed ID: 14673999 Fractalkine Mediates Natural Killer-dependent Antitumor Responses in Vivo Cancer Research. Nov, 2003 | Pubmed ID: 14612547 Two Novel Fully Functional Isoforms of CX3CR1 Are Potent HIV Coreceptors Journal of Immunology (Baltimore, Md. : 1950). Nov, 2003 | Pubmed ID: 14607932 Genetic Control of HIV Disease Trends in Microbiology. Aug, 2003 | Pubmed ID: 12915097 Fractalkine/CX3CL1 Production by Human Aortic Smooth Muscle Cells Impairs Monocyte Procoagulant and Inflammatory Responses Cytokine. Mar, 2003 | Pubmed ID: 12824004 The Chemokine Receptor CX3CR1 Controls Homing and Anti-viral Potencies of CD8 Effector-memory T Lymphocytes in HIV-infected Patients AIDS (London, England). Jun, 2003 | Pubmed ID: 12799549 Deleterious Genetic Influence of CX3CR1 Genotypes on HIV-1 Disease Progression Journal of Acquired Immune Deficiency Syndromes (1999). Mar, 2003 | Pubmed ID: 12626895 Decreased Atherosclerotic Lesion Formation in CX3CR1/apolipoprotein E Double Knockout Mice Circulation. Feb, 2003 | Pubmed ID: 12600915 Perforin-dependent Brain-infiltrating Cytotoxic CD8+ T Lymphocytes Mediate Experimental Cerebral Malaria Pathogenesis Journal of Immunology (Baltimore, Md. : 1950). Feb, 2003 | Pubmed ID: 12574396 Cloning and Functional Characterization of the Human Fractalkine Receptor Promoter Regions The Biochemical Journal. Dec, 2002 | Pubmed ID: 12234253 Suivi moelle osseuse de souris monocytes Pauline Hamon1, Mathieu Paul Rodero1, Christophe Combadière1, Alexandre Boissonnas1 1Centre d'Immunologie et des Maladies Infectieuses (CIMI), INSERM, U1135, CNRS, ERL 8255, Sorbonne Universités, UPMC Univ Paris 06, CR7 Immunology and Infection
Suivi moelle osseuse de souris monocytes Pauline Hamon1, Mathieu Paul Rodero1, Christophe Combadière1, Alexandre Boissonnas1 1Centre d'Immunologie et des Maladies Infectieuses (CIMI), INSERM, U1135, CNRS, ERL 8255, Sorbonne Universités, UPMC Univ Paris 06, CR7 Immunology and Infection
