In JoVE (1)
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Articles by Christopher J. Handwerk in JoVE
Inducing Cre-lox Recombination in Mouse Cerebral Cortex Through In Utero Electroporation Katherine M. Bland*1, Zachary O. Casey*1, Christopher J. Handwerk*1, Z. Logan Holley1, George S. Vidal1 1Department of Biology, James Madison University Cell-autonomous functions of genes in the brain can be studied by inducing loss or gain of function in sparse populations of cells. Here, we describe in utero electroporation to deliver Cre recombinase into sparse populations of developing cortical neurons with floxed genes to cause loss of function in vivo.