Christopher K. Breuer Center for Regenerative Medicine Nationwide Children’s Hospital Biography Publications Institution JoVE Articles Christopher K. Breuer has not added a biography. If you are Christopher K. Breuer and would like to personalize this page please email our Author Liaison for assistance. Publications Hemodynamic Performance of Tissue-engineered Vascular Grafts in Fontan Patients NPJ Regenerative Medicine. Jul, 2021 | Pubmed ID: 34294733 On the Shape and Structure of the Murine Pulmonary Heart Valve Scientific Reports. Jul, 2021 | Pubmed ID: 34234231 Regeneration of Partially Decellularized Tracheal Scaffolds in a Mouse Model of Orthotopic Tracheal Replacement Journal of Tissue Engineering. Jan-Dec, 2021 | Pubmed ID: 34164107 Tracheal Macrophages During Regeneration and Repair of Long-Segment Airway Defects The Laryngoscope. Jun, 2021 | Pubmed ID: 34153127 Sex and Tamoxifen Confound Murine Experimental Studies in Cardiovascular Tissue Engineering Scientific Reports. Apr, 2021 | Pubmed ID: 33850181 Current Challenges and Solutions to Tissue Engineering of Large-scale Cardiac Constructs Current Cardiology Reports. 03, 2021 | Pubmed ID: 33733317 Tissue Engineering: Relevance to Neonatal Congenital Heart Disease Seminars in Fetal & Neonatal Medicine. Feb, 2021 | Pubmed ID: 33674254 Improvement of a Novel Small-diameter Tissue-engineered Arterial Graft With Heparin Conjugation The Annals of Thoracic Surgery. 04, 2021 | Pubmed ID: 32946845 Electrospun Tissue-Engineered Arterial Graft Thickness Affects Long-Term Composition and Mechanics Tissue Engineering. Part A. 05, 2021 | Pubmed ID: 32854586 Spatial and Temporal Analysis of Host Cells in Tracheal Graft Implantation The Laryngoscope. 02, 2021 | Pubmed ID: 32521060 Imatinib Attenuates Neotissue Formation During Vascular Remodeling in an Arterial Bioresorbable Vascular Graft JVS-vascular Science. 2020 | Pubmed ID: 34223286 Biology and Biomechanics of the Heart Valve Extracellular Matrix Journal of Cardiovascular Development and Disease. Dec, 2020 | Pubmed ID: 33339213 Evaluating the Longevity of the Fontan Pathway Pediatric Cardiology. Dec, 2020 | Pubmed ID: 33161457 Tissue Engineered Vascular Graft Recipient Interleukin 10 Status Is Critical for Preventing Thrombosis Advanced Healthcare Materials. 12, 2020 | Pubmed ID: 33073543 Effects of Braiding Parameters on Tissue Engineered Vascular Graft Development Advanced Healthcare Materials. 12, 2020 | Pubmed ID: 33063452 The Effect of Pore Diameter on Neo-tissue Formation in Electrospun Biodegradable Tissue-engineered Arterial Grafts in a Large Animal Model Acta Biomaterialia. 10, 2020 | Pubmed ID: 32822820 The Evaluation of a Tissue-engineered Cardiac Patch Seeded with Hips Derived Cardiac Progenitor Cells in a Rat Left Ventricular Model PloS One. 2020 | Pubmed ID: 32511282 Spontaneous Reversal of Stenosis in Tissue-engineered Vascular Grafts Science Translational Medicine. 04, 2020 | Pubmed ID: 32238576 A Computational Bio-chemo-mechanical Model of in Vivo Tissue-engineered Vascular Graft Development Integrative Biology : Quantitative Biosciences from Nano to Macro. 04, 2020 | Pubmed ID: 32222759 Fetal Transcatheter Trileaflet Heart Valve Hemodynamics: Implications of Scaling on Valve Mechanics and Turbulence Annals of Biomedical Engineering. Jun, 2020 | Pubmed ID: 32052320 Different Degradation Rates of Nanofiber Vascular Grafts in Small and Large Animal Models Journal of Tissue Engineering and Regenerative Medicine. 02, 2020 | Pubmed ID: 31756767 Deconstructing Tissue Engineered Trachea: Assessing the Role of Synthetic Scaffolds, Segmental Replacement and Cell Seeding on Graft Performance Acta Biomaterialia. 01, 2020 | Pubmed ID: 31707085 Degradation and Evaluation of Polycaprolactone, Poly(ε-caprolactone-co-L-lactide), and Poly-L-lactic Acid As Scaffold Sealant Polymers for Murine Tissue-engineered Vascular Grafts Regenerative Medicine. 07, 2019 | Pubmed ID: 31342857 Optimization of Tissue-Engineered Vascular Graft Design Using Computational Modeling Tissue Engineering. Part C, Methods. 10, 2019 | Pubmed ID: 31218941 Differential Outcomes of Venous and Arterial Tissue Engineered Vascular Grafts Highlight the Importance of Coupling Long-term Implantation Studies with Computational Modeling Acta Biomaterialia. 08, 2019 | Pubmed ID: 31200116 Early Natural History of Neotissue Formation in Tissue-engineered Vascular Grafts in a Murine Model Regenerative Medicine. 05, 2019 | Pubmed ID: 31180275 Factors Influencing Poor Outcomes in Synthetic Tissue-Engineered Tracheal Replacement Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 09, 2019 | Pubmed ID: 31035858 Mouse Model of Tracheal Replacement With Electrospun Nanofiber Scaffolds The Annals of Otology, Rhinology, and Laryngology. Jan, 2019 | Pubmed ID: 30700095 Implantation of VEGF-functionalized Cell-free Vascular Grafts: Regenerative and Immunological Response FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 04, 2019 | Pubmed ID: 30629890 Clinical Validation and Reproducibility of Endoscopic Airway Measurement in Pediatric Aerodigestive Evaluation International Journal of Pediatric Otorhinolaryngology. Jan, 2019 | Pubmed ID: 30554710 Magnetic Resonance Imaging of Shear Stress and Wall Thickness in Tissue-Engineered Vascular Grafts Tissue Engineering. Part C, Methods. 08, 2018 | Pubmed ID: 29978768 Angiotensin II Receptor I Blockade Prevents Stenosis of Tissue Engineered Vascular Grafts FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2018 | Pubmed ID: 29906242 Bone Marrow-derived Mononuclear Cell Seeded Bioresorbable Vascular Graft Improves Acute Graft Patency by Inhibiting Thrombus Formation Via Platelet Adhesion International Journal of Cardiology. Sep, 2018 | Pubmed ID: 29887474 Oversized Biodegradable Arterial Grafts Promote Enhanced Neointimal Tissue Formation Tissue Engineering. Part A. Aug, 2018 | Pubmed ID: 29431029 Tissue-engineered Vascular Grafts in Children With Congenital Heart Disease: Intermediate Term Follow-up Seminars in Thoracic and Cardiovascular Surgery. 2018 | Pubmed ID: 29427773 Tissue-Engineered Heart Valves: A Call for Mechanistic Studies Tissue Engineering. Part B, Reviews. 06, 2018 | Pubmed ID: 29327671 Designing a Tissue-engineered Tracheal Scaffold for Preclinical Evaluation International Journal of Pediatric Otorhinolaryngology. Jan, 2018 | Pubmed ID: 29287858 Stress Analysis-Driven Design of Bilayered Scaffolds for Tissue-Engineered Vascular Grafts Journal of Biomechanical Engineering. Dec, 2017 | Pubmed ID: 28886204 Role of Bone Marrow Mononuclear Cell Seeding for Nanofiber Vascular Grafts Tissue Engineering. Part A. Jun, 2017 | Pubmed ID: 28486019 Endoscopic Management of Tissue-engineered Tracheal Graft Stenosis in an Ovine Model The Laryngoscope. 10, 2017 | Pubmed ID: 28349659 Intravascular Ultrasound Characterization of a Tissue-Engineered Vascular Graft in an Ovine Model Journal of Cardiovascular Translational Research. Apr, 2017 | Pubmed ID: 28097523 Tropoelastin Inhibits Intimal Hyperplasia of Mouse Bioresorbable Arterial Vascular Grafts Acta Biomaterialia. 04, 2017 | Pubmed ID: 28025048 Preclinical Study of Patient-specific Cell-free Nanofiber Tissue-engineered Vascular Grafts Using 3-dimensional Printing in a Sheep Model The Journal of Thoracic and Cardiovascular Surgery. Apr, 2017 | Pubmed ID: 27938900 Fast-degrading Bioresorbable Arterial Vascular Graft with High Cellular Infiltration Inhibits Calcification of the Graft Journal of Vascular Surgery. 07, 2017 | Pubmed ID: 27687327 Tissue-engineered Cardiac Patch Seeded with Human Induced Pluripotent Stem Cell Derived Cardiomyocytes Promoted the Regeneration of Host Cardiomyocytes in a Rat Model Journal of Cardiothoracic Surgery. Dec, 2016 | Pubmed ID: 27906085 Objective Characterization of Airway Dimensions Using Image Processing International Journal of Pediatric Otorhinolaryngology. Dec, 2016 | Pubmed ID: 27863622 Impaired Von Willebrand Factor Adhesion and Platelet Response in Thrombospondin-2 Knockout Mice Blood. 09, 2016 | Pubmed ID: 27471233 Tissue-Engineered Small Diameter Arterial Vascular Grafts from Cell-Free Nanofiber PCL/Chitosan Scaffolds in a Sheep Model PloS One. 2016 | Pubmed ID: 27467821 Clinical Translation of Tissue Engineered Trachea Grafts The Annals of Otology, Rhinology, and Laryngology. Nov, 2016 | Pubmed ID: 27411362 Pilot Mouse Study of 1 Mm Inner Diameter (ID) Vascular Graft Using Electrospun Poly(ester Urea) Nanofibers Advanced Healthcare Materials. 09, 2016 | Pubmed ID: 27390286 Setting Global Standards for Stem Cell Research and Clinical Translation: The 2016 ISSCR Guidelines Stem Cell Reports. 06, 2016 | Pubmed ID: 27185282 Novel Bioresorbable Vascular Graft With Sponge-Type Scaffold As a Small-Diameter Arterial Graft The Annals of Thoracic Surgery. Sep, 2016 | Pubmed ID: 27154152 TGF-β Receptor 1 Inhibition Prevents Stenosis of Tissue-engineered Vascular Grafts by Reducing Host Mononuclear Phagocyte Activation FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2016 | Pubmed ID: 27059717 Long-Term Functional Efficacy of a Novel Electrospun Poly(Glycerol Sebacate)-Based Arterial Graft in Mice Annals of Biomedical Engineering. 08, 2016 | Pubmed ID: 26795977 Cardiovascular Tissue Engineering: Preclinical Validation to Bedside Application Physiology (Bethesda, Md.). Jan, 2016 | Pubmed ID: 26661524 Effect of Cell Seeding on Neotissue Formation in a Tissue Engineered Trachea Journal of Pediatric Surgery. Jan, 2016 | Pubmed ID: 26552897 A Mouse Model of Endocardial Fibroelastosis Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Nov-Dec, 2015 | Pubmed ID: 26363814 Influence of Posttransplant Lymphoproliferative Disorder on Survival in Children After Heart Transplantation Pediatric Cardiology. Dec, 2015 | Pubmed ID: 26187515 Cilostazol, Not Aspirin, Prevents Stenosis of Bioresorbable Vascular Grafts in a Venous Model Arteriosclerosis, Thrombosis, and Vascular Biology. Sep, 2015 | Pubmed ID: 26183618 C-Cell Neoplasia in Asymptomatic Carriers of RET Mutation in Extracellular Cysteine-Rich and Intracellular Tyrosine Kinase Domain Human Pathology. Aug, 2015 | Pubmed ID: 26033033 Hemodynamic Characterization of a Mouse Model for Investigating the Cellular and Molecular Mechanisms of Neotissue Formation in Tissue-Engineered Heart Valves Tissue Engineering. Part C, Methods. Sep, 2015 | Pubmed ID: 25915105 Development of Small Diameter Nanofiber Tissue Engineered Arterial Grafts PloS One. 2015 | Pubmed ID: 25830942 The Innate Immune System Contributes to Tissue-engineered Vascular Graft Performance FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2015 | Pubmed ID: 25713026 Biomechanical Diversity Despite Mechanobiological Stability in Tissue Engineered Vascular Grafts Two Years Post-implantation Tissue Engineering. Part A. May, 2015 | Pubmed ID: 25710791 Comparison of the Biological Equivalence of Two Methods for Isolating Bone Marrow Mononuclear Cells for Fabricating Tissue-engineered Vascular Grafts Tissue Engineering. Part C, Methods. Jun, 2015 | Pubmed ID: 25397868 A Hypothesis-driven Parametric Study of Effects of Polymeric Scaffold Properties on Tissue Engineered Neovessel Formation Acta Biomaterialia. Jan, 2015 | Pubmed ID: 25288519 Well-organized Neointima of Large-pore Poly(L-lactic Acid) Vascular Graft Coated with Poly(L-lactic-co-ε-caprolactone) Prevents Calcific Deposition Compared to Small-pore Electrospun Poly(L-lactic Acid) Graft in a Mouse Aortic Implantation Model Atherosclerosis. Dec, 2014 | Pubmed ID: 25463106 Targeted Imaging of Matrix Metalloproteinase Activity in the Evaluation of Remodeling Tissue-engineered Vascular Grafts Implanted in a Growing Lamb Model The Journal of Thoracic and Cardiovascular Surgery. Nov, 2014 | Pubmed ID: 24952823 Comparison of a Closed System to a Standard Open Technique for Preparing Tissue Engineered Vascular Grafts Tissue Engineering. Part C, Methods. May, 2014 | Pubmed ID: 24866863 Evaluation of Remodeling Process in Small-diameter Cell-free Tissue-engineered Arterial Graft Journal of Vascular Surgery. Apr, 2014 | Pubmed ID: 24745941 Characterization of Evolving Biomechanical Properties of Tissue Engineered Vascular Grafts in the Arterial Circulation Journal of Biomechanics. Jun, 2014 | Pubmed ID: 24702863 Regenerative Implants for Cardiovascular Tissue Engineering Translational Research : the Journal of Laboratory and Clinical Medicine. Apr, 2014 | Pubmed ID: 24589506 Vessel Bioengineering Circulation Journal : Official Journal of the Japanese Circulation Society. Dec, 2013 | Pubmed ID: 24334558 Surgery and Sample Processing for Correlative Imaging of the Murine Pulmonary Valve Yifei Liu1, Yong-Ung Lee2, Tai Yi2, Ken Wu3, Cedric Bouchet-Marquis3, Han Chan3, Christopher K. Breuer2, David W. McComb1 1Center for Electron Microscopy and Analysis, The Department of Materials Science and Engineering, Ohio State University, 2Center for Regenerative Medicine, Nationwide Children’s Hospital, 3Thermo Fisher Scientific JoVE 62581 Engineering Transplantation of Pulmonary Valve Using a Mouse Model of Heterotopic Heart Transplantation Yong-Ung Lee1, Tai Yi1, Iyore James1, Shuhei Tara1, Alexander J. Stuber1, Kejal V. Shah1, Avione Y. Lee1, Tadahisa Sugiura1, Narutoshi Hibino2, Toshiharu Shinoka1, Christopher K. Breuer1,3 1Tissue Engineering Program and Surgical Research, Nationwide Children's Hospital, 2Cardiothoracic Surgery, Nationwide Children's Hospital, 3Pediatric Surgery, Nationwide Children's Hospital JoVE 51695 Medicine Implantation of Inferior Vena Cava Interposition Graft in Mouse Model Yong-Ung Lee1, Tai Yi1, Shuhei Tara1, Avione Y. Lee1, Narutoshi Hibino1, Toshiharu Shinoka2, Christopher K. Breuer1,3 1Tissue Engineering Program and Surgical Research, Nationwide Children's Hospital, 2Department of Cardiothoracic Surgery, Nationwide Children's Hospital, 3Pediatric Surgery, Nationwide Children's Hospital JoVE 51632 Medicine
Surgery and Sample Processing for Correlative Imaging of the Murine Pulmonary Valve Yifei Liu1, Yong-Ung Lee2, Tai Yi2, Ken Wu3, Cedric Bouchet-Marquis3, Han Chan3, Christopher K. Breuer2, David W. McComb1 1Center for Electron Microscopy and Analysis, The Department of Materials Science and Engineering, Ohio State University, 2Center for Regenerative Medicine, Nationwide Children’s Hospital, 3Thermo Fisher Scientific JoVE 62581 Engineering
Transplantation of Pulmonary Valve Using a Mouse Model of Heterotopic Heart Transplantation Yong-Ung Lee1, Tai Yi1, Iyore James1, Shuhei Tara1, Alexander J. Stuber1, Kejal V. Shah1, Avione Y. Lee1, Tadahisa Sugiura1, Narutoshi Hibino2, Toshiharu Shinoka1, Christopher K. Breuer1,3 1Tissue Engineering Program and Surgical Research, Nationwide Children's Hospital, 2Cardiothoracic Surgery, Nationwide Children's Hospital, 3Pediatric Surgery, Nationwide Children's Hospital JoVE 51695 Medicine
Implantation of Inferior Vena Cava Interposition Graft in Mouse Model Yong-Ung Lee1, Tai Yi1, Shuhei Tara1, Avione Y. Lee1, Narutoshi Hibino1, Toshiharu Shinoka2, Christopher K. Breuer1,3 1Tissue Engineering Program and Surgical Research, Nationwide Children's Hospital, 2Department of Cardiothoracic Surgery, Nationwide Children's Hospital, 3Pediatric Surgery, Nationwide Children's Hospital JoVE 51632 Medicine