Christopher M. Dobson

Publications

• Mapping Surface Hydrophobicity of α-Synuclein Oligomers at the Nanoscale
  Nano Letters. Nov, 2018   |   Pubmed ID: 30380895
• Quantifying Co-Oligomer Formation by α-Synuclein
  ACS Nano. Nov, 2018   |   Pubmed ID: 30371053
• Statistical Mechanics of Globular Oligomer Formation by Protein Molecules
  The Journal of Physical Chemistry. B. Oct, 2018   |   Pubmed ID: 30336667
• SAR by Kinetics for Drug Discovery in Protein Misfolding Diseases
  Proceedings of the National Academy of Sciences of the United States of America. 10, 2018   |   Pubmed ID: 30257937
• Microfluidic Deposition for Resolving Single-molecule Protein Architecture and Heterogeneity
  Nature Communications. Sep, 2018   |   Pubmed ID: 30250131
• Proteasome-targeted Nanobodies Alleviate Pathology and Functional Decline in an α-synuclein-based Parkinson's Disease Model
  NPJ Parkinson's Disease. Month, 2018   |   Pubmed ID: 30155513
• Obituary: Nico Van Nuland 1961-2017
  European Biophysics Journal : EBJ. Sep, 2018   |   Pubmed ID: 30116857
• C-terminal Truncation of α-synuclein Promotes Amyloid Fibril Amplification at Physiological PH
  Chemical Science. Jul, 2018   |   Pubmed ID: 30061982
• Nanoscopic Characterisation of Individual Endogenous Protein Aggregates in Human Neuronal Cells
  Chembiochem : a European Journal of Chemical Biology. Oct, 2018   |   Pubmed ID: 30051958
• Conserved S/T Residues of the Human Chaperone DNAJB6 Are Required for Effective Inhibition of Aβ42 Amyloid Fibril Formation
  Biochemistry. Aug, 2018   |   Pubmed ID: 30024736
• Structural Differences Between Toxic and Nontoxic HypF-N Oligomers
  Chemical Communications (Cambridge, England). Aug, 2018   |   Pubmed ID: 30020284
• Stabilization and Characterization of Cytotoxic Aβ Oligomers Isolated from an Aggregation Reaction in the Presence of Zinc Ions
  ACS Chemical Neuroscience. Aug, 2018   |   Pubmed ID: 29986583
• Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine
  ACS Chemical Biology. Aug, 2018   |   Pubmed ID: 29953201
• Kinetic Barriers to α-synuclein Protofilament Formation and Conversion into Mature Fibrils
  Chemical Communications (Cambridge, England). Jul, 2018   |   Pubmed ID: 29951679
• Single-Molecule Characterization of the Interactions Between Extracellular Chaperones and Toxic α-Synuclein Oligomers
  Cell Reports. Jun, 2018   |   Pubmed ID: 29924993
• On-chip Measurements of Protein Unfolding from Direct Observations of Micron-scale Diffusion
  Chemical Science. Apr, 2018   |   Pubmed ID: 29780480
• Cooperative Assembly of Hsp70 Subdomain Clusters
  Biochemistry. Jul, 2018   |   Pubmed ID: 29763298
• Cholesterol Catalyses Aβ42 Aggregation Through a Heterogeneous Nucleation Pathway in the Presence of Lipid Membranes
  Nature Chemistry. Jun, 2018   |   Pubmed ID: 29736006
• Exploring the Role of Post-translational Modifications in Regulating α-synuclein Interactions by Studying the Effects of Phosphorylation on Nanobody Binding
  Protein Science : a Publication of the Protein Society. Jul, 2018   |   Pubmed ID: 29603451
• Molecular Determinants of the Interaction of EGCG with Ordered and Disordered Proteins
  Biopolymers. Aug, 2018   |   Pubmed ID: 29603125
• Distinct Thermodynamic Signatures of Oligomer Generation in the Aggregation of the Amyloid-β Peptide
  Nature Chemistry. May, 2018   |   Pubmed ID: 29581486
• Microfluidic Approaches for Probing Amyloid Assembly and Behaviour
  Lab on a Chip. 03, 2018   |   Pubmed ID: 29527600
• Bifunctional Fluorescent Probes for Detection of Amyloid Aggregates and Reactive Oxygen Species
  Royal Society Open Science. Feb, 2018   |   Pubmed ID: 29515860
• Chemical Kinetics for Bridging Molecular Mechanisms and Macroscopic Measurements of Amyloid Fibril Formation
  Annual Review of Physical Chemistry. 04, 2018   |   Pubmed ID: 29490200
• Massively Parallel C. Elegans Tracking Provides Multi-dimensional Fingerprints for Phenotypic Discovery
  Journal of Neuroscience Methods. Aug, 2018   |   Pubmed ID: 29452179
• The Small Heat Shock Protein Hsp27 Binds α-synuclein Fibrils, Preventing Elongation and Cytotoxicity
  The Journal of Biological Chemistry. Mar, 2018   |   Pubmed ID: 29382725
• Biophotonics of Native Silk Fibrils
  Macromolecular Bioscience. Apr, 2018   |   Pubmed ID: 29377575
• Direct Observation of Oligomerization by Single Molecule Fluorescence Reveals a Multistep Aggregation Mechanism for the Yeast Prion Protein Ure2
  Journal of the American Chemical Society. 02, 2018   |   Pubmed ID: 29357227
• Optical Structural Analysis of Individual α-Synuclein Oligomers
  Angewandte Chemie (International Ed. in English). Apr, 2018   |   Pubmed ID: 29342318
• Microfluidic Diffusion Platform for Characterizing the Sizes of Lipid Vesicles and the Thermodynamics of Protein-Lipid Interactions
  Analytical Chemistry. Mar, 2018   |   Pubmed ID: 29313342
• Hsp70 Inhibits the Nucleation and Elongation of Tau and Sequesters Tau Aggregates with High Affinity
  ACS Chemical Biology. Mar, 2018   |   Pubmed ID: 29300447
• Immunization with α-synuclein/Grp94 Reshapes Peripheral Immunity and Suppresses Microgliosis in a Chronic Parkinsonism Model
  Glia. 01, 2018   |   Pubmed ID: 29024008
• The Contribution of Biophysical and Structural Studies of Protein Self-assembly to the Design of Therapeutic Strategies for Amyloid Diseases
  Neurobiology of Disease. Jan, 2018   |   Pubmed ID: 28709995
• Structural Basis of Membrane Disruption and Cellular Toxicity by α-synuclein Oligomers
  Science (New York, N.Y.). 12, 2017   |   Pubmed ID: 29242346
• Inhibiting the Ca Influx Induced by Human CSF
  Cell Reports. Dec, 2017   |   Pubmed ID: 29241555
• Scaling Behaviour and Rate-determining Steps in Filamentous Self-assembly
  Chemical Science. Oct, 2017   |   Pubmed ID: 29147538
• Delivery of Native Proteins into C. Elegans Using a Transduction Protocol Based on Lipid Vesicles
  Scientific Reports. Nov, 2017   |   Pubmed ID: 29118344
• Clusterin Protects Neurons Against Intracellular Proteotoxicity
  Acta Neuropathologica Communications. Nov, 2017   |   Pubmed ID: 29115989
• Application of Lysine-specific Labeling to Detect Transient Interactions Present During Human Lysozyme Amyloid Fibril Formation
  Scientific Reports. Nov, 2017   |   Pubmed ID: 29101328
• Thermodynamics of Polypeptide Supramolecular Assembly in the Short-Chain Limit
  Journal of the American Chemical Society. 11, 2017   |   Pubmed ID: 28994295
• Modulation of Electrostatic Interactions to Reveal a Reaction Network Unifying the Aggregation Behaviour of the Aβ42 Peptide and Its Variants
  Chemical Science. Jun, 2017   |   Pubmed ID: 28979758
• Absolute Quantification of Amyloid Propagons by Digital Microfluidics
  Analytical Chemistry. Nov, 2017   |   Pubmed ID: 28972786
• Gradient-free Determination of Isoelectric Points of Proteins on Chip
  Physical Chemistry Chemical Physics : PCCP. Aug, 2017   |   Pubmed ID: 28817152
• Sequential Release of Proteins from Structured Multishell Microcapsules
  Biomacromolecules. Oct, 2017   |   Pubmed ID: 28792742
• Silk Micrococoons for Protein Stabilisation and Molecular Encapsulation
  Nature Communications. 07, 2017   |   Pubmed ID: 28722016
• The Relevance of Contact-independent Cell-to-cell Transfer of TDP-43 and SOD1 in Amyotrophic Lateral Sclerosis
  Biochimica Et Biophysica Acta. Molecular Basis of Disease. 11, 2017   |   Pubmed ID: 28711596
• Monomeric and Fibrillar α-synuclein Exert Opposite Effects on the Catalytic Cycle That Promotes the Proliferation of Aβ42 Aggregates
  Proceedings of the National Academy of Sciences of the United States of America. 07, 2017   |   Pubmed ID: 28698377
• Selective Targeting of Primary and Secondary Nucleation Pathways in Aβ42 Aggregation Using a Rational Antibody Scanning Method
  Science Advances. Jun, 2017   |   Pubmed ID: 28691099
• Nanobodies Raised Against Monomeric ɑ-synuclein Inhibit Fibril Formation and Destabilize Toxic Oligomeric Species
  BMC Biology. 07, 2017   |   Pubmed ID: 28673288
• Protein Homeostasis of a Metastable Subproteome Associated with Alzheimer's Disease
  Proceedings of the National Academy of Sciences of the United States of America. 07, 2017   |   Pubmed ID: 28652376
• Phage Display and Kinetic Selection of Antibodies That Specifically Inhibit Amyloid Self-replication
  Proceedings of the National Academy of Sciences of the United States of America. 06, 2017   |   Pubmed ID: 28584111
• Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
  Annual Review of Biochemistry. 06, 2017   |   Pubmed ID: 28498720
• Amyloid-like Fibrils from an α-Helical Transmembrane Protein
  Biochemistry. 06, 2017   |   Pubmed ID: 28493669
• Ultrasensitive Measurement of Ca Influx into Lipid Vesicles Induced by Protein Aggregates
  Angewandte Chemie (International Ed. in English). Jun, 2017   |   Pubmed ID: 28474754
• Spinal Motor Neuron Protein Supersaturation Patterns Are Associated with Inclusion Body Formation in ALS
  Proceedings of the National Academy of Sciences of the United States of America. 05, 2017   |   Pubmed ID: 28396410
• Inhibition of α-Synuclein Fibril Elongation by Hsp70 Is Governed by a Kinetic Binding Competition Between α-Synuclein Species
  Biochemistry. 03, 2017   |   Pubmed ID: 28230968
• A Natural Product Inhibits the Initiation of α-synuclein Aggregation and Suppresses Its Toxicity
  Proceedings of the National Academy of Sciences of the United States of America. 02, 2017   |   Pubmed ID: 28096355
• The Amyloid Phenomenon and Its Links with Human Disease
  Cold Spring Harbor Perspectives in Biology. Jun, 2017   |   Pubmed ID: 28062560
• Systematic Development of Small Molecules to Inhibit Specific Microscopic Steps of Aβ42 Aggregation in Alzheimer's Disease
  Proceedings of the National Academy of Sciences of the United States of America. 01, 2017   |   Pubmed ID: 28011763
• Multi-dimensional Super-resolution Imaging Enables Surface Hydrophobicity Mapping
  Nature Communications. 12, 2016   |   Pubmed ID: 27929085
• The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme
  Biophysical Journal. Dec, 2016   |   Pubmed ID: 27926837
• Bifunctional Anti-Non-Amyloid Component α-Synuclein Nanobodies Are Protective In Situ
  PloS One. Month, 2016   |   Pubmed ID: 27824888
• β-Synuclein Suppresses Both the Initiation and Amplification Steps of α-synuclein Aggregation Via Competitive Binding to Surfaces
  Scientific Reports. 11, 2016   |   Pubmed ID: 27808107
• Structural Basis of Synaptic Vesicle Assembly Promoted by α-synuclein
  Nature Communications. 09, 2016   |   Pubmed ID: 27640673
• Binding Affinity of Amyloid Oligomers to Cellular Membranes is a Generic Indicator of Cellular Dysfunction in Protein Misfolding Diseases
  Scientific Reports. 09, 2016   |   Pubmed ID: 27619987
• Mutations Associated with Familial Parkinson's Disease Alter the Initiation and Amplification Steps of α-synuclein Aggregation
  Proceedings of the National Academy of Sciences of the United States of America. 09, 2016   |   Pubmed ID: 27573854
• A Protein Homeostasis Signature in Healthy Brains Recapitulates Tissue Vulnerability to Alzheimer's Disease
  Science Advances. 08, 2016   |   Pubmed ID: 27532054
• Protein Aggregate-Ligand Binding Assays Based on Microfluidic Diffusional Separation
  Chembiochem : a European Journal of Chemical Biology. 10, 2016   |   Pubmed ID: 27472818
• The Chaperone HSPB8 Reduces the Accumulation of Truncated TDP-43 Species in Cells and Protects Against TDP-43-mediated Toxicity
  Human Molecular Genetics. 09, 2016   |   Pubmed ID: 27466192
• Towards a Structural Biology of the Hydrophobic Effect in Protein Folding
  Scientific Reports. 07, 2016   |   Pubmed ID: 27461719
• Quantification of the Relative Contributions of Loss-of-function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies
  The Journal of Biological Chemistry. 09, 2016   |   Pubmed ID: 27445339
• Synthesis of Nonequilibrium Supramolecular Peptide Polymers on a Microfluidic Platform
  Journal of the American Chemical Society. 08, 2016   |   Pubmed ID: 27387359
• Quantitative Analysis of Co-oligomer Formation by Amyloid-beta Peptide Isoforms
  Scientific Reports. 06, 2016   |   Pubmed ID: 27346247
• Chemical Properties of Lipids Strongly Affect the Kinetics of the Membrane-induced Aggregation of α-synuclein
  Proceedings of the National Academy of Sciences of the United States of America. 06, 2016   |   Pubmed ID: 27298346
• Structural Ensembles of Membrane-bound α-Synuclein Reveal the Molecular Determinants of Synaptic Vesicle Affinity
  Scientific Reports. 06, 2016   |   Pubmed ID: 27273030
• The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model
  Molecular Cell. Apr, 2016   |   Pubmed ID: 27151442
• Structural Effects of Two Camelid Nanobodies Directed to Distinct C-Terminal Epitopes on α-Synuclein
  Biochemistry. 06, 2016   |   Pubmed ID: 27096466
• Structural Characterization of the Interaction of α-synuclein Nascent Chains with the Ribosomal Surface and Trigger Factor
  Proceedings of the National Academy of Sciences of the United States of America. May, 2016   |   Pubmed ID: 27092002
• A Transcriptional Signature of Alzheimer's Disease is Associated with a Metastable Subproteome at Risk for Aggregation
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2016   |   Pubmed ID: 27071083
• Kinetic Analysis Reveals the Diversity of Microscopic Mechanisms Through Which Molecular Chaperones Suppress Amyloid Formation
  Nature Communications. Mar, 2016   |   Pubmed ID: 27009901
• Nanoscopic Insights into Seeding Mechanisms and Toxicity of α-synuclein Species in Neurons
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2016   |   Pubmed ID: 26993805
• Ca2+ is a Key Factor in α-synuclein-induced Neurotoxicity
  Journal of Cell Science. 05, 2016   |   Pubmed ID: 26989132
• Quantitative Thermophoretic Study of Disease-related Protein Aggregates
  Scientific Reports. Mar, 2016   |   Pubmed ID: 26984748
• Amyloid-β and α-Synuclein Decrease the Level of Metal-Catalyzed Reactive Oxygen Species by Radical Scavenging and Redox Silencing
  Journal of the American Chemical Society. Mar, 2016   |   Pubmed ID: 26967463
• An Anticancer Drug Suppresses the Primary Nucleation Reaction That Initiates the Production of the Toxic Aβ42 Aggregates Linked with Alzheimer's Disease
  Science Advances. Feb, 2016   |   Pubmed ID: 26933687
• A Structural Ensemble of a Ribosome-nascent Chain Complex During Cotranslational Protein Folding
  Nature Structural & Molecular Biology. Apr, 2016   |   Pubmed ID: 26926436
• A Fragment-Based Method of Creating Small-Molecule Libraries to Target the Aggregation of Intrinsically Disordered Proteins
  ACS Combinatorial Science. Mar, 2016   |   Pubmed ID: 26923286
• Kinetic Model of the Aggregation of Alpha-synuclein Provides Insights into Prion-like Spreading
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2016   |   Pubmed ID: 26884195
• An Environmentally Sensitive Fluorescent Dye As a Multidimensional Probe of Amyloid Formation
  The Journal of Physical Chemistry. B. Mar, 2016   |   Pubmed ID: 26865546
• Hamiltonian Dynamics of Protein Filament Formation
  Physical Review Letters. Jan, 2016   |   Pubmed ID: 26849615
• Automated Ex Situ Assays of Amyloid Formation on a Microfluidic Platform
  Biophysical Journal. Feb, 2016   |   Pubmed ID: 26840721
• Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human Biofluids
  ACS Chemical Neuroscience. Mar, 2016   |   Pubmed ID: 26800462
• Molecular Mechanisms of Protein Aggregation from Global Fitting of Kinetic Models
  Nature Protocols. Feb, 2016   |   Pubmed ID: 26741409
• Microfluidic Diffusion Analysis of the Sizes and Interactions of Proteins Under Native Solution Conditions
  ACS Nano. Jan, 2016   |   Pubmed ID: 26678709
• Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease
  Antioxidants & Redox Signaling. Mar, 2016   |   Pubmed ID: 26564470
• Chaperome Screening Leads to Identification of Grp94/Gp96 and FKBP4/52 As Modulators of the α-synuclein-elicited Immune Response
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2016   |   Pubmed ID: 26443817
• Single-molecule FRET Studies on Alpha-synuclein Oligomerization of Parkinson's Disease Genetically Related Mutants
  Scientific Reports. Nov, 2015   |   Pubmed ID: 26582456
• Solvent Exposure of Tyr10 As a Probe of Structural Differences Between Monomeric and Aggregated Forms of the Amyloid-β Peptide
  Biochemical and Biophysical Research Communications. Dec, 2015   |   Pubmed ID: 26551456
• The Length Distribution of Frangible Biofilaments
  The Journal of Chemical Physics. Oct, 2015   |   Pubmed ID: 26520548
• SOD1 Protein Aggregates Stimulate Macropinocytosis in Neurons to Facilitate Their Propagation
  Molecular Neurodegeneration. Oct, 2015   |   Pubmed ID: 26520394
• Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies
  Current Alzheimer Research. Month, 2015   |   Pubmed ID: 26510979
• Structure-Free Validation of Residual Dipolar Coupling and Paramagnetic Relaxation Enhancement Measurements of Disordered Proteins
  Biochemistry. Nov, 2015   |   Pubmed ID: 26479087
• Conformational Effects of the A21G Flemish Mutation on the Aggregation of Amyloid β Peptide
  Biological & Pharmaceutical Bulletin. Month, 2015   |   Pubmed ID: 26424029
• Latent Analysis of Unmodified Biomolecules and Their Complexes in Solution with Attomole Detection Sensitivity
  Nature Chemistry. Oct, 2015   |   Pubmed ID: 26391079
• Biophysical Approaches for the Study of Interactions Between Molecular Chaperones and Protein Aggregates
  Chemical Communications (Cambridge, England). Oct, 2015   |   Pubmed ID: 26328629
• Fast Flow Microfluidics and Single-molecule Fluorescence for the Rapid Characterization of α-synuclein Oligomers
  Analytical Chemistry. Sep, 2015   |   Pubmed ID: 26258431
• Force Generation by the Growth of Amyloid Aggregates
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2015   |   Pubmed ID: 26195762
• Alpha-2-Macroglobulin Is Acutely Sensitive to Freezing and Lyophilization: Implications for Structural and Functional Studies
  PloS One. Month, 2015   |   Pubmed ID: 26103636
• Neuronal Cx3cr1 Deficiency Protects Against Amyloid β-Induced Neurotoxicity
  PloS One. Month, 2015   |   Pubmed ID: 26038823
• Enzymatically Active Microgels from Self-Assembling Protein Nanofibrils for Microflow Chemistry
  ACS Nano. Jun, 2015   |   Pubmed ID: 26030507
• The Influence of Novel Gemini Surfactants Containing Cycloalkyl Side-chains on the Structural Phases of DNA in Solution
  Colloids and Surfaces. B, Biointerfaces. Jul, 2015   |   Pubmed ID: 25969417
• Widespread Proteome Remodeling and Aggregation in Aging C. Elegans
  Cell. May, 2015   |   Pubmed ID: 25957690
• Structure of a Single-chain Fv Bound to the 17 N-terminal Residues of Huntingtin Provides Insights into Pathogenic Amyloid Formation and Suppression
  Journal of Molecular Biology. Jun, 2015   |   Pubmed ID: 25861763
• Structural Characterization of Toxic Oligomers That Are Kinetically Trapped During α-synuclein Fibril Formation
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2015   |   Pubmed ID: 25855634
• Investigating the Mechanisms of Amylolysis of Starch Granules by Solution-state NMR
  Biomacromolecules. May, 2015   |   Pubmed ID: 25815624
• A Molecular Chaperone Breaks the Catalytic Cycle That Generates Toxic Aβ Oligomers
  Nature Structural & Molecular Biology. Mar, 2015   |   Pubmed ID: 25686087
• Lipid Vesicles Trigger α-synuclein Aggregation by Stimulating Primary Nucleation
  Nature Chemical Biology. Mar, 2015   |   Pubmed ID: 25643172
• Supersaturation is a Major Driving Force for Protein Aggregation in Neurodegenerative Diseases
  Trends in Pharmacological Sciences. Feb, 2015   |   Pubmed ID: 25636813
• Structure of a Low-population Intermediate State in the Release of an Enzyme Product
  ELife. Jan, 2015   |   Pubmed ID: 25575179
• Protein Microgels from Amyloid Fibril Networks
  ACS Nano. Jan, 2015   |   Pubmed ID: 25469621
• Chaperoned Amyloid Proteins for Immune Manipulation: α-Synuclein/Hsp70 Shifts Immunity Toward a Modulatory Phenotype
  Immunity, Inflammation and Disease. Dec, 2014   |   Pubmed ID: 25866630
• Ostwald's Rule of Stages Governs Structural Transitions and Morphology of Dipeptide Supramolecular Polymers
  Nature Communications. Nov, 2014   |   Pubmed ID: 25391268
• A Relationship Between the Transient Structure in the Monomeric State and the Aggregation Propensities of α-synuclein and β-synuclein
  Biochemistry. Nov, 2014   |   Pubmed ID: 25389903
• Single-molecule Imaging Reveals That Small Amyloid-β1-42 Oligomers Interact with the Cellular Prion Protein (PrP(C))
  Chembiochem : a European Journal of Chemical Biology. Nov, 2014   |   Pubmed ID: 25294384
• Interaction of the Molecular Chaperone DNAJB6 with Growing Amyloid-beta 42 (Aβ42) Aggregates Leads to Sub-stoichiometric Inhibition of Amyloid Formation
  The Journal of Biological Chemistry. Nov, 2014   |   Pubmed ID: 25217638
• Antibodies and Protein Misfolding: From Structural Research Tools to Therapeutic Strategies
  Biochimica Et Biophysica Acta. Nov, 2014   |   Pubmed ID: 25194824
• The Physical Chemistry of the Amyloid Phenomenon: Thermodynamics and Kinetics of Filamentous Protein Aggregation
  Essays in Biochemistry. Month, 2014   |   Pubmed ID: 25131584
• Differences in Nucleation Behavior Underlie the Contrasting Aggregation Kinetics of the Aβ40 and Aβ42 Peptides
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2014   |   Pubmed ID: 24938782
• Direct Observation of the Three Regions in α-synuclein That Determine Its Membrane-bound Behaviour
  Nature Communications. May, 2014   |   Pubmed ID: 24871041
• Direct Observations of Amyloid β Self-assembly in Live Cells Provide Insights into Differences in the Kinetics of Aβ(1-40) and Aβ(1-42) Aggregation
  Chemistry & Biology. Jun, 2014   |   Pubmed ID: 24856820
• The Amyloid State and Its Association with Protein Misfolding Diseases
  Nature Reviews. Molecular Cell Biology. Jun, 2014   |   Pubmed ID: 24854788
• Solution Conditions Determine the Relative Importance of Nucleation and Growth Processes in α-synuclein Aggregation
  Proceedings of the National Academy of Sciences of the United States of America. May, 2014   |   Pubmed ID: 24817693
• Hypochlorite-induced Structural Modifications Enhance the Chaperone Activity of Human α2-macroglobulin
  Proceedings of the National Academy of Sciences of the United States of America. May, 2014   |   Pubmed ID: 24799681
• Understanding the Influence of Codon Translation Rates on Cotranslational Protein Folding
  Accounts of Chemical Research. May, 2014   |   Pubmed ID: 24784899
• Nucleation-conversion-polymerization Reactions of Biological Macromolecules with Prenucleation Clusters
  Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. Mar, 2014   |   Pubmed ID: 24730879
• Oligomer-targeting with a Conformational Antibody Fragment Promotes Toxicity in Aβ-expressing Flies
  Acta Neuropathologica Communications. Apr, 2014   |   Pubmed ID: 24725347
• Rare Individual Amyloid-β Oligomers Act on Astrocytes to Initiate Neuronal Damage
  Biochemistry. Apr, 2014   |   Pubmed ID: 24717093
• Dynamics and Timekeeping in Biological Systems
  Annual Review of Biochemistry. Month, 2014   |   Pubmed ID: 24606145
• Chemical Kinetics for Drug Discovery to Combat Protein Aggregation Diseases
  Trends in Pharmacological Sciences. Mar, 2014   |   Pubmed ID: 24560688
• Targeting the Intrinsically Disordered Structural Ensemble of α-synuclein by Small Molecules As a Potential Therapeutic Strategy for Parkinson's Disease
  PloS One. Month, 2014   |   Pubmed ID: 24551051
• A Simple Lattice Model That Captures Protein Folding, Aggregation and Amyloid Formation
  PloS One. Month, 2014   |   Pubmed ID: 24454816
• Kinetic Modelling Indicates That Fast-translating Codons Can Coordinate Cotranslational Protein Folding by Avoiding Misfolded Intermediates
  Nature Communications. Month, 2014   |   Pubmed ID: 24394622
• Direct Observation of Heterogeneous Amyloid Fibril Growth Kinetics Via Two-color Super-resolution Microscopy
  Nano Letters. Jan, 2014   |   Pubmed ID: 24303845
• Single Point Mutations Induce a Switch in the Molecular Mechanism of the Aggregation of the Alzheimer's Disease Associated Aβ42 Peptide
  ACS Chemical Biology. Feb, 2014   |   Pubmed ID: 24199868
• A Clear View of Polymorphism, Twist, and Chirality in Amyloid Fibril Formation
  ACS Nano. Dec, 2013   |   Pubmed ID: 24359171
• Higher Order Amyloid Fibril Structure by MAS NMR and DNP Spectroscopy
  Journal of the American Chemical Society. Dec, 2013   |   Pubmed ID: 24304221
• Preconditioning of Microglia by α-synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation
  PloS One. Month, 2013   |   Pubmed ID: 24236103
• Widespread Aggregation and Neurodegenerative Diseases Are Associated with Supersaturated Proteins
  Cell Reports. Nov, 2013   |   Pubmed ID: 24183671
• In-cell NMR Characterization of the Secondary Structure Populations of a Disordered Conformation of α-synuclein Within E. Coli Cells
  PloS One. Month, 2013   |   Pubmed ID: 23991082
• Characterization of the Interdomain Motions in Hen Lysozyme Using Residual Dipolar Couplings As Replica-averaged Structural Restraints in Molecular Dynamics Simulations
  Biochemistry. Sep, 2013   |   Pubmed ID: 23941501
• A Nanobody Binding to Non-amyloidogenic Regions of the Protein Human Lysozyme Enhances Partial Unfolding but Inhibits Amyloid Fibril Formation
  The Journal of Physical Chemistry. B. Oct, 2013   |   Pubmed ID: 23919586
• Identification of Small-molecule Binding Pockets in the Soluble Monomeric Form of the Aβ42 Peptide
  The Journal of Chemical Physics. Jul, 2013   |   Pubmed ID: 23883055
• Hsp70 Oligomerization is Mediated by an Interaction Between the Interdomain Linker and the Substrate-binding Domain
  PloS One. Month, 2013   |   Pubmed ID: 23840795
• α-Synuclein Senses Lipid Packing Defects and Induces Lateral Expansion of Lipids Leading to Membrane Remodeling
  The Journal of Biological Chemistry. Jul, 2013   |   Pubmed ID: 23740253
• Proliferation of Amyloid-β42 Aggregates Occurs Through a Secondary Nucleation Mechanism
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2013   |   Pubmed ID: 23703910
• A Label-free, Quantitative Assay of Amyloid Fibril Growth Based on Intrinsic Fluorescence
  Chembiochem : a European Journal of Chemical Biology. May, 2013   |   Pubmed ID: 23592254
• Nanobodies Raised Against Monomeric α-synuclein Distinguish Between Fibrils at Different Maturation Stages
  Journal of Molecular Biology. Jul, 2013   |   Pubmed ID: 23557833
• Influence of Specific HSP70 Domains on Fibril Formation of the Yeast Prion Protein Ure2
  Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. May, 2013   |   Pubmed ID: 23530260
• Atomic Structure and Hierarchical Assembly of a Cross-β Amyloid Fibril
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2013   |   Pubmed ID: 23513222
• Electrostatic Effects in Filamentous Protein Aggregation
  Biophysical Journal. Mar, 2013   |   Pubmed ID: 23473495
• Protein Amyloids Develop an Intrinsic Fluorescence Signature During Aggregation
  The Analyst. Apr, 2013   |   Pubmed ID: 23420088
• Protease-activated Alpha-2-macroglobulin Can Inhibit Amyloid Formation Via Two Distinct Mechanisms
  FEBS Letters. Mar, 2013   |   Pubmed ID: 23353684
• Single Molecule Characterization of the Interactions Between Amyloid-β Peptides and the Membranes of Hippocampal Cells
  Journal of the American Chemical Society. Jan, 2013   |   Pubmed ID: 23339742
• In Vivo Translation Rates Can Substantially Delay the Cotranslational Folding of the Escherichia Coli Cytosolic Proteome
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2013   |   Pubmed ID: 23256155
• Analysis of the Native Structure, Stability and Aggregation of Biotinylated Human Lysozyme
  PloS One. Month, 2012   |   Pubmed ID: 23166837
• Amyloid-β Oligomers Are Sequestered by Both Intracellular and Extracellular Chaperones
  Biochemistry. Nov, 2012   |   Pubmed ID: 23106396
• Twisting Transition Between Crystalline and Fibrillar Phases of Aggregated Peptides
  Physical Review Letters. Oct, 2012   |   Pubmed ID: 23102370
• Nanobodies As Structural Probes of Protein Misfolding and Fibril Formation
  Methods in Molecular Biology (Clifton, N.J.). Month, 2012   |   Pubmed ID: 22886275
• Role of Elongation and Secondary Pathways in S6 Amyloid Fibril Growth
  Biophysical Journal. May, 2012   |   Pubmed ID: 22824281
• Molecular Mechanisms Used by Chaperones to Reduce the Toxicity of Aberrant Protein Oligomers
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2012   |   Pubmed ID: 22802614
• Characterizing Intermolecular Interactions That Initiate Native-like Protein Aggregation
  Biophysical Journal. Jun, 2012   |   Pubmed ID: 22713575
• Trigger Factor Slows Co-translational Folding Through Kinetic Trapping While Sterically Protecting the Nascent Chain from Aberrant Cytosolic Interactions
  Journal of the American Chemical Society. Jul, 2012   |   Pubmed ID: 22680285
• Prediction of Variable Translation Rate Effects on Cotranslational Protein Folding
  Nature Communications. May, 2012   |   Pubmed ID: 22643895
• Direct Observation of the Interconversion of Normal and Toxic Forms of α-synuclein
  Cell. May, 2012   |   Pubmed ID: 22632969
• Measuring the Kinetics of Amyloid Fibril Elongation Using Quartz Crystal Microbalances
  Methods in Molecular Biology (Clifton, N.J.). Month, 2012   |   Pubmed ID: 22528086
• Intrinsic Disorder Modulates Protein Self-assembly and Aggregation
  Proceedings of the National Academy of Sciences of the United States of America. May, 2012   |   Pubmed ID: 22509003
• Detailed Analysis of the Energy Barriers for Amyloid Fibril Growth
  Angewandte Chemie (International Ed. in English). May, 2012   |   Pubmed ID: 22489083
• Expression in Drosophila of Tandem Amyloid β Peptides Provides Insights into Links Between Aggregation and Neurotoxicity
  The Journal of Biological Chemistry. Jun, 2012   |   Pubmed ID: 22461632
• From Macroscopic Measurements to Microscopic Mechanisms of Protein Aggregation
  Journal of Molecular Biology. Aug, 2012   |   Pubmed ID: 22406275
• The Aggregation and Neurotoxicity of TDP-43 and Its ALS-associated 25 KDa Fragment Are Differentially Affected by Molecular Chaperones in Drosophila
  PloS One. Month, 2012   |   Pubmed ID: 22384095
• Disease-related Amyloidogenic Variants of Human Lysozyme Trigger the Unfolded Protein Response and Disturb Eye Development in Drosophila Melanogaster
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jan, 2012   |   Pubmed ID: 21965601
• ¹H, ¹³C and ¹⁵N Resonance Assignments of Human Muscle Acylphosphatase
  Biomolecular NMR Assignments. Apr, 2012   |   Pubmed ID: 21643968
• The Extracellular Chaperone Clusterin Sequesters Oligomeric Forms of the Amyloid-β(1-40) Peptide
  Nature Structural & Molecular Biology. Dec, 2011   |   Pubmed ID: 22179788
• Experimental Free Energy Surfaces Reveal the Mechanisms of Maintenance of Protein Solubility
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011   |   Pubmed ID: 22160682
• Inversion of the Balance Between Hydrophobic and Hydrogen Bonding Interactions in Protein Folding and Aggregation
  PLoS Computational Biology. Oct, 2011   |   Pubmed ID: 22022239
• Nucleated Polymerisation in the Presence of Pre-formed Seed Filaments
  International Journal of Molecular Sciences. Month, 2011   |   Pubmed ID: 22016630
• Probing Small Molecule Binding to Amyloid Fibrils
  Physical Chemistry Chemical Physics : PCCP. Dec, 2011   |   Pubmed ID: 22006124
• Binding of the Molecular Chaperone αB-crystallin to Aβ Amyloid Fibrils Inhibits Fibril Elongation
  Biophysical Journal. Oct, 2011   |   Pubmed ID: 21961594
• Observation of Spatial Propagation of Amyloid Assembly from Single Nuclei
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2011   |   Pubmed ID: 21876182
• Nucleated Polymerization with Secondary Pathways. III. Equilibrium Behavior and Oligomer Populations
  The Journal of Chemical Physics. Aug, 2011   |   Pubmed ID: 21842956
• Nucleated Polymerization with Secondary Pathways. II. Determination of Self-consistent Solutions to Growth Processes Described by Non-linear Master Equations
  The Journal of Chemical Physics. Aug, 2011   |   Pubmed ID: 21842955
• Nucleated Polymerization with Secondary Pathways. I. Time Evolution of the Principal Moments
  The Journal of Chemical Physics. Aug, 2011   |   Pubmed ID: 21842954
• Protein Solubility and Protein Homeostasis: a Generic View of Protein Misfolding Disorders
  Cold Spring Harbor Perspectives in Biology. Dec, 2011   |   Pubmed ID: 21825020
• Native-state Stability Determines the Extent of Degradation Relative to Secretion of Protein Variants from Pichia Pastoris
  PloS One. Month, 2011   |   Pubmed ID: 21818368
• In Situ Measurements of the Formation and Morphology of Intracellular β-amyloid Fibrils by Super-resolution Fluorescence Imaging
  Journal of the American Chemical Society. Aug, 2011   |   Pubmed ID: 21793568
• Intermolecular Structure Determination of Amyloid Fibrils with Magic-angle Spinning and Dynamic Nuclear Polarization NMR
  Journal of the American Chemical Society. Sep, 2011   |   Pubmed ID: 21774549
• Probing Protein Aggregation with Quartz Crystal Microbalances
  Methods in Molecular Biology (Clifton, N.J.). Month, 2011   |   Pubmed ID: 21713635
• The IFly Tracking System for an Automated Locomotor and Behavioural Analysis of Drosophila Melanogaster
  Integrative Biology : Quantitative Biosciences from Nano to Macro. Jul, 2011   |   Pubmed ID: 21698336
• Conserved C-terminal Charge Exerts a Profound Influence on the Aggregation Rate of α-synuclein
  Journal of Molecular Biology. Aug, 2011   |   Pubmed ID: 21689664
• Disulfide Bonds Reduce the Toxicity of the Amyloid Fibrils Formed by an Extracellular Protein
  Angewandte Chemie (International Ed. in English). Jul, 2011   |   Pubmed ID: 21671315
• Metastability of Native Proteins and the Phenomenon of Amyloid Formation
  Journal of the American Chemical Society. Sep, 2011   |   Pubmed ID: 21650202
• Perturbation of the Stability of Amyloid Fibrils Through Alteration of Electrostatic Interactions
  Biophysical Journal. Jun, 2011   |   Pubmed ID: 21641324
• Population of Nonnative States of Lysozyme Variants Drives Amyloid Fibril Formation
  Journal of the American Chemical Society. May, 2011   |   Pubmed ID: 21528861
• Detection of Early Locomotor Abnormalities in a Drosophila Model of Alzheimer's Disease
  Journal of Neuroscience Methods. Apr, 2011   |   Pubmed ID: 21315762
• A FRET Sensor for Non-invasive Imaging of Amyloid Formation in Vivo
  Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. Feb, 2011   |   Pubmed ID: 21308945
• Protein Dynamics: Moore's Law in Molecular Biology
  Current Biology : CB. Jan, 2011   |   Pubmed ID: 21256436
• Relationship Between Prion Propensity and the Rates of Individual Molecular Steps of Fibril Assembly
  The Journal of Biological Chemistry. Apr, 2011   |   Pubmed ID: 21233211
• New Scenarios of Protein Folding Can Occur on the Ribosome
  Journal of the American Chemical Society. Jan, 2011   |   Pubmed ID: 21204555
• Interactions Between Amyloidophilic Dyes and Their Relevance to Studies of Amyloid Inhibitors
  Biophysical Journal. Nov, 2010   |   Pubmed ID: 21081099
• Transient Tertiary Structure Formation Within the Ribosome Exit Port
  Journal of the American Chemical Society. Dec, 2010   |   Pubmed ID: 21062068
• Glial Innate Immunity Generated by Non-aggregated Alpha-synuclein in Mouse: Differences Between Wild-type and Parkinson's Disease-linked Mutants
  PloS One. Oct, 2010   |   Pubmed ID: 21048992
• Local Cooperativity in an Amyloidogenic State of Human Lysozyme Observed at Atomic Resolution
  Journal of the American Chemical Society. Nov, 2010   |   Pubmed ID: 20958028
• Frequency Factors in a Landscape Model of Filamentous Protein Aggregation
  Physical Review Letters. Jun, 2010   |   Pubmed ID: 20873942
• Stabilization of Neurotoxic Alzheimer Amyloid-beta Oligomers by Protein Engineering
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2010   |   Pubmed ID: 20713699
• High-resolution MAS NMR Analysis of PI3-SH3 Amyloid Fibrils: Backbone Conformation and Implications for Protofilament Assembly and Structure
  Biochemistry. Sep, 2010   |   Pubmed ID: 20707313
• Surface Attachment of Protein Fibrils Via Covalent Modification Strategies
  The Journal of Physical Chemistry. B. Sep, 2010   |   Pubmed ID: 20695458
• The Non-core Regions of Human Lysozyme Amyloid Fibrils Influence Cytotoxicity
  Journal of Molecular Biology. Oct, 2010   |   Pubmed ID: 20624399
• Structure and Properties of a Complex of α-synuclein and a Single-domain Camelid Antibody
  Journal of Molecular Biology. Sep, 2010   |   Pubmed ID: 20620148
• Physicochemical Determinants of Chaperone Requirements
  Journal of Molecular Biology. Jul, 2010   |   Pubmed ID: 20416322
• Intrinsic Determinants of Neurotoxic Aggregate Formation by the Amyloid Beta Peptide
  Biophysical Journal. Apr, 2010   |   Pubmed ID: 20409489
• A Non-natural Variant of Human Lysozyme (I59T) Mimics the in Vitro Behaviour of the I56T Variant That is Responsible for a Form of Familial Amyloidosis
  Protein Engineering, Design & Selection : PEDS. Jul, 2010   |   Pubmed ID: 20382744
• Sequestration of the Abeta Peptide Prevents Toxicity and Promotes Degradation in Vivo
  PLoS Biology. Mar, 2010   |   Pubmed ID: 20305716
• The Interaction of AlphaB-crystallin with Mature Alpha-synuclein Amyloid Fibrils Inhibits Their Elongation
  Biophysical Journal. Mar, 2010   |   Pubmed ID: 20197038
• Differential Phospholipid Binding of Alpha-synuclein Variants Implicated in Parkinson's Disease Revealed by Solution NMR Spectroscopy
  Biochemistry. Feb, 2010   |   Pubmed ID: 20041693
• Folding Study of Venus Reveals a Strong Ion Dependence of Its Yellow Fluorescence Under Mildly Acidic Conditions
  The Journal of Biological Chemistry. Feb, 2010   |   Pubmed ID: 19901033
• Probing Ribosome-nascent Chain Complexes Produced in Vivo by NMR Spectroscopy
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2009   |   Pubmed ID: 20018739
• Analysis of Sub-tauc and Supra-tauc Motions in Protein Gbeta1 Using Molecular Dynamics Simulations
  Biophysical Journal. Nov, 2009   |   Pubmed ID: 19883594
• Chaperone Proteostasis in Parkinson's Disease: Stabilization of the Hsp70/alpha-synuclein Complex by Hip
  The EMBO Journal. Dec, 2009   |   Pubmed ID: 19875982
• Long-range Correlations Between Aliphatic 13C Nuclei in Protein MAS NMR Spectroscopy
  Angewandte Chemie (International Ed. in English). Month, 2009   |   Pubmed ID: 19562810
• Multiple Tight Phospholipid-binding Modes of Alpha-synuclein Revealed by Solution NMR Spectroscopy
  Journal of Molecular Biology. Jul, 2009   |   Pubmed ID: 19481095
• Amyloid Formation by the Pro-inflammatory S100A8/A9 Proteins in the Ageing Prostate
  PloS One. Month, 2009   |   Pubmed ID: 19440546
• Experimental Characterization of Disordered and Ordered Aggregates Populated During the Process of Amyloid Fibril Formation
  Proceedings of the National Academy of Sciences of the United States of America. May, 2009   |   Pubmed ID: 19416886
• A Generic Mechanism of Emergence of Amyloid Protofilaments from Disordered Oligomeric Aggregates
  PLoS Computational Biology. Nov, 2008   |   Pubmed ID: 19008938
• Recombinant Amyloid Beta-peptide Production by Coexpression with an Affibody Ligand
  BMC Biotechnology. Oct, 2008   |   Pubmed ID: 18973685
• Direct Characterization of Amyloidogenic Oligomers by Single-molecule Fluorescence
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2008   |   Pubmed ID: 18796612
• Immunological Features of Alpha-synuclein in Parkinson's Disease
  Journal of Cellular and Molecular Medicine. Oct, 2008   |   Pubmed ID: 18671754
• A Coupled Equilibrium Shift Mechanism in Calmodulin-mediated Signal Transduction
  Structure (London, England : 1993). May, 2008   |   Pubmed ID: 18462678
• Molecular Determinants of the Aggregation Behavior of Alpha- and Beta-synuclein
  Protein Science : a Publication of the Protein Society. May, 2008   |   Pubmed ID: 18436957
• Systematic in Vivo Analysis of the Intrinsic Determinants of Amyloid Beta Pathogenicity
  PLoS Biology. Oct, 2007   |   Pubmed ID: 17973577
• Structural Reorganisation and Potential Toxicity of Oligomeric Species Formed During the Assembly of Amyloid Fibrils
  PLoS Computational Biology. Sep, 2007   |   Pubmed ID: 17941703
• Structure and Dynamics of a Ribosome-bound Nascent Chain by NMR Spectroscopy
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2007   |   Pubmed ID: 17940046
• Kinetics and Thermodynamics of Amyloid Formation from Direct Measurements of Fluctuations in Fibril Mass
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2007   |   Pubmed ID: 17540728
• Similarities in the Thermodynamics and Kinetics of Aggregation of Disease-related Abeta(1-40) Peptides
  Protein Science : a Publication of the Protein Society. Jun, 2007   |   Pubmed ID: 17525469
• Characterization of the Nanoscale Properties of Individual Amyloid Fibrils
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2006   |   Pubmed ID: 17038504
• Amyloid Fibril Formation Can Proceed from Different Conformations of a Partially Unfolded Protein
  Biophysical Journal. Dec, 2005   |   Pubmed ID: 16169975
• Determination of the Folding Transition States of Barnase by Using PhiI-value-restrained Simulations Validated by Double Mutant PhiIJ-values
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2005   |   Pubmed ID: 16116084
• Rational Design of Aggregation-resistant Bioactive Peptides: Reengineering Human Calcitonin
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2005   |   Pubmed ID: 16006528
• Multiple Subsets of Side-chain Packing in Partially Folded States of Alpha-lactalbumins
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2005   |   Pubmed ID: 15956205
• A Glimpse at the Organization of the Protein Universe
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2005   |   Pubmed ID: 15827120
• The Formation of Spherulites by Amyloid Fibrils of Bovine Insulin
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2004   |   Pubmed ID: 15381766
• Heteronuclear NMR Investigations of Dynamic Regions of Intact Escherichia Coli Ribosomes
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2004   |   Pubmed ID: 15263071
• Short Amino Acid Stretches Can Mediate Amyloid Formation in Globular Proteins: the Src Homology 3 (SH3) Case
  Proceedings of the National Academy of Sciences of the United States of America. May, 2004   |   Pubmed ID: 15123800
• Exploring Amyloid Formation by a De Novo Design
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004   |   Pubmed ID: 15070736
• High-resolution Molecular Structure of a Peptide in an Amyloid Fibril Determined by Magic Angle Spinning NMR Spectroscopy
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2004   |   Pubmed ID: 14715898
• Structures and Relative Free Energies of Partially Folded States of Proteins
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2003   |   Pubmed ID: 14657374
• The Circularization of Amyloid Fibrils Formed by Apolipoprotein C-II
  Biophysical Journal. Dec, 2003   |   Pubmed ID: 14645087
• Chemical Modification of Insulin in Amyloid Fibrils
  Protein Science : a Publication of the Protein Society. Nov, 2003   |   Pubmed ID: 14573875
• Calculation of Mutational Free Energy Changes in Transition States for Protein Folding
  Biophysical Journal. Aug, 2003   |   Pubmed ID: 12885664
• Molecular Conformation of a Peptide Fragment of Transthyretin in an Amyloid Fibril
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2002   |   Pubmed ID: 12481032
• De Novo Designed Peptide-based Amyloid Fibrils
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2002   |   Pubmed ID: 12456886
• Altered Aggregation Properties of Mutant Gamma-crystallins Cause Inherited Cataract
  The EMBO Journal. Nov, 2002   |   Pubmed ID: 12426373
• The Behaviour of Polyamino Acids Reveals an Inverse Side Chain Effect in Amyloid Structure Formation
  The EMBO Journal. Nov, 2002   |   Pubmed ID: 12411486
• Studies of the Aggregation of Mutant Proteins in Vitro Provide Insights into the Genetics of Amyloid Diseases
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2002   |   Pubmed ID: 12374855
• Solution Conditions Can Promote Formation of Either Amyloid Protofilaments or Mature Fibrils from the HypF N-terminal Domain
  Protein Science : a Publication of the Protein Society. Dec, 2001   |   Pubmed ID: 11714922