Christopher N. Boddy

Publications

• Sampling Terrestrial Environments for Bacterial Polyketides
  Molecules (Basel, Switzerland). Apr, 2017  |   Pubmed ID: 28468277
• Natural Products: Mapping an Amazing Thicket
  Nature Chemical Biology. Dec, 2016  |   Pubmed ID: 27984578
• Portable, On-Demand Biomolecular Manufacturing
  Cell. Sep, 2016  |   Pubmed ID: 27662092
• Total Biosynthesis of Legionaminic Acid, a Bacterial Sialic Acid Analogue
  Angewandte Chemie (International Ed. in English). Sep, 2016  |   Pubmed ID: 27538580
• First-in-class Small Molecule Potentiators of Cancer Virotherapy
  Scientific Reports. May, 2016  |   Pubmed ID: 27226390
• The Use of ClusterMine360 for the Analysis of Polyketide and Nonribosomal Peptide Biosynthetic Pathways
  Methods in Molecular Biology (Clifton, N.J.). 2016  |   Pubmed ID: 26831712
• Diastereoseletive Transannular Oxa-Conjugate Addition Generates the 2,6-cis-Disubstituted Tetrahydropyran of Neopeltolide
  The Journal of Organic Chemistry. Jan, 2016  |   Pubmed ID: 26675500
• Towards a Characterization of the Structural Determinants of Specificity in the Macrocyclizing Thioesterase for Deoxyerythronolide B Biosynthesis
  Biochimica Et Biophysica Acta. Mar, 2016  |   Pubmed ID: 26592346
• Polyketide Synthase and Non-ribosomal Peptide Synthetase Thioesterase Selectivity: Logic Gate or a Victim of Fate?
  Natural Product Reports. Feb, 2016  |   Pubmed ID: 25642666
• Thermoplasmonic SsDNA Dynamic Release from Gold Nanoparticles Examined with Advanced Fluorescence Microscopy
  The Journal of Physical Chemistry Letters. Apr, 2015  |   Pubmed ID: 26263158
• Draft Genome Sequence of Streptomyces Sp. Strain PBH53, Isolated from an Urban Environment
  Genome Announcements. Jul, 2015  |   Pubmed ID: 26227608
• Modulation of Antifreeze Activity and the Effect Upon Post-thaw HepG2 Cell Viability After Cryopreservation
  Cryobiology. Apr, 2015  |   Pubmed ID: 25595636
• Resorcylic Acid Lactone Biosynthesis Relies on a Stereotolerant Macrocyclizing Thioesterase
  Organic Letters. Nov, 2014  |   Pubmed ID: 25372311
• An Evolutionary Model Encompassing Substrate Specificity and Reactivity of Type I Polyketide Synthase Thioesterases
  Chembiochem : a European Journal of Chemical Biology. Dec, 2014  |   Pubmed ID: 25354333
• Salvadenosine, a 5'-deoxy-5'-(methylthio) Nucleoside from the Bahamian Tunicate Didemnum Sp
  The Journal of Organic Chemistry. Nov, 2014  |   Pubmed ID: 25284474
• Genetic Analysis of the Assimilation of C5-dicarboxylic Acids in Pseudomonas Aeruginosa PAO1
  Journal of Bacteriology. Jul, 2014  |   Pubmed ID: 24794562
• Habitat-specific Type I Polyketide Synthases in Soils and Street Sediments
  Journal of Industrial Microbiology & Biotechnology. Jan, 2014  |   Pubmed ID: 24241933
• Bioinformatics Tools for Genome Mining of Polyketide and Non-ribosomal Peptides
  Journal of Industrial Microbiology & Biotechnology. Feb, 2014  |   Pubmed ID: 24174214
• Elucidation of Gephyronic Acid Biosynthetic Pathway Revealed Unexpected SAM-dependent Methylations
  Journal of Natural Products. Dec, 2013  |   Pubmed ID: 24298873
• The Role of Transcription in Heterologous Expression of Polyketides in Bacterial Hosts
  Natural Product Reports. Oct, 2013  |   Pubmed ID: 24061690
• Biosynthesis of Ebelactone A: Isotopic Tracer, Advanced Precursor and Genetic Studies Reveal a Thioesterase-independent Cyclization to Give a Polyketide β-lactone
  The Journal of Antibiotics. Jul, 2013  |   Pubmed ID: 23801186
• Alternative Sigma Factor Over-Expression Enables Heterologous Expression of a Type II Polyketide Biosynthetic Pathway in Escherichia Coli
  PloS One. 2013  |   Pubmed ID: 23724102
• Gene PA2449 is Essential for Glycine Metabolism and Pyocyanin Biosynthesis in Pseudomonas Aeruginosa PAO1
  Journal of Bacteriology. May, 2013  |   Pubmed ID: 23457254
• ClusterMine360: a Database of Microbial PKS/NRPS Biosynthesis
  Nucleic Acids Research. Jan, 2013  |   Pubmed ID: 23104377
• Non-canonical Regioisomerizations and a 'Diels-Alderase' Are Likely Essential in the Biosynthesis of Spiculoic Acid A
  Bioorganic & Medicinal Chemistry Letters. Aug, 2012  |   Pubmed ID: 22801647
• 6-Deoxyerythronolide B Synthase Thioesterase-catalyzed Macrocyclization is Highly Stereoselective
  Organic Letters. May, 2012  |   Pubmed ID: 22519860
• Reinvestigation of Coenzyme Q10 Isolation from Sporidiobolus Johnsonii
  Chemistry & Biodiversity. Jun, 2011  |   Pubmed ID: 21674778
• Heterologous Expression of the Oxytetracycline Biosynthetic Pathway in Myxococcus Xanthus
  Applied and Environmental Microbiology. Apr, 2010  |   Pubmed ID: 20208031
• A Thioesterase from an Iterative Fungal Polyketide Synthase Shows Macrocyclization and Cross Coupling Activity and May Play a Role in Controlling Iterative Cycling Through Product Offloading
  Biochemistry. Jul, 2009  |   Pubmed ID: 19530704
• Polyketide Synthase Thioesterases Catalyze Rapid Hydrolysis of Peptidyl Thioesters
  Bioorganic & Medicinal Chemistry Letters. Mar, 2009  |   Pubmed ID: 19188064
• Biomimetic Transannular Oxa-conjugate Addition Approach to the 2,6-disubstituted Dihydropyran of Laulimalide Yields an Unprecedented Transannular Oxetane
  The Journal of Organic Chemistry. Feb, 2009  |   Pubmed ID: 19159194
• Examining the Role of Hydrogen Bonding Interactions in the Substrate Specificity for the Loading Step of Polyketide Synthase Thioesterase Domains
  Biochemistry. Nov, 2008  |   Pubmed ID: 18850723
• Orthogonal Ligation: a Three Piece Assembly of a PNA-peptide-PNA Conjugate
  Chemical Communications (Cambridge, England). Jun, 2008  |   Pubmed ID: 18688310
• A New Mechanism for Benzopyrone Formation in Aromatic Polyketide Biosynthesis
  Journal of the American Chemical Society. Aug, 2007  |   Pubmed ID: 17625867
• Sialic Acid and N-acyl Sialic Acid Analog Production by Fermentation of Metabolically and Genetically Engineered Escherichia Coli
  Organic & Biomolecular Chemistry. Jun, 2007  |   Pubmed ID: 17551639
• The Thioesterase Domain from the Pimaricin and Erythromycin Biosynthetic Pathways Can Catalyze Hydrolysis of Simple Thioester Substrates
  Bioorganic & Medicinal Chemistry Letters. Jun, 2007  |   Pubmed ID: 17428661
• Total Biosynthesis of Antitumor Nonribosomal Peptides in Escherichia Coli
  Nature Chemical Biology. Aug, 2006  |   Pubmed ID: 16799553
• Sweetening Cyclic Peptide Libraries
  Chemistry & Biology. Dec, 2004  |   Pubmed ID: 15610840
• Precursor-directed Biosynthesis of Epothilone in Escherichia Coli
  Journal of the American Chemical Society. Jun, 2004  |   Pubmed ID: 15198579
• Understanding Substrate Specificity of Polyketide Synthase Modules by Generating Hybrid Multimodular Synthases
  The Journal of Biological Chemistry. Oct, 2003  |   Pubmed ID: 12923197
• Epothilone C Macrolactonization and Hydrolysis Are Catalyzed by the Isolated Thioesterase Domain of Epothilone Polyketide Synthase
  Journal of the American Chemical Society. Mar, 2003  |   Pubmed ID: 12643694
• Atropselective Macrocyclization of Diaryl Ether Ring Systems: Application to the Synthesis of Vancomycin Model Systems
  Journal of the American Chemical Society. Sep, 2002  |   Pubmed ID: 12197747
• Does CIP Nomenclature Adequately Handle Molecules with Multiple Stereoelements? A Case Study of Vancomycin and Cognates We Would Like to Thank Professor Dieter Hellwinkel for Pointing out to Us the Stereochemical Discrepancies in Our Review6 and Elsewhere in the Literature, and Kurt Mislow for Stimulating and Useful Discussions
  Angewandte Chemie (International Ed. in English). Feb, 2001  |   Pubmed ID: 11241596