Christopher Fang-Yen Department of Bioengineering, School of Engineering and Applied Sciences University of Pennsylvania Biography Publications Institution JoVE Articles Christopher Fang-Yen has not added a biography. If you are Christopher Fang-Yen and would like to personalize this page please email our Author Liaison for assistance. Publications Pharyngeal Timing and Particle Transport Defects in Feeding Mutants Journal of Neurophysiology. Aug, 2022 | Pubmed ID: 35730757 An Imaging System for Monitoring C. Elegans Behavior and Aging Methods in Molecular Biology (Clifton, N.J.). 2022 | Pubmed ID: 35320574 Optogenetic Perturbation of Individual C. Elegans Pharyngeal Neurons While Monitoring Feeding Behavior Methods in Molecular Biology (Clifton, N.J.). 2022 | Pubmed ID: 35320563 Cryopreservation of Dehydrated with Multiple Recoveries Using a Granular Medium MicroPublication Biology. 2021 | Pubmed ID: 34712912 Phase Response Analyses Support a Relaxation Oscillator Model of Locomotor Rhythm Generation in ELife. Sep, 2021 | Pubmed ID: 34569934 DAF-16/FoxO and DAF-12/VDR Control Cellular Plasticity Both Cell-autonomously and Via Interorgan Signaling PLoS Biology. Apr, 2021 | Pubmed ID: 33891586 Thermal Laser Ablation with Tunable Lesion Size Reveals Multiple Origins of Seizure-like Convulsions in Caenorhabditis Elegans Scientific Reports. Mar, 2021 | Pubmed ID: 33658607 Preconditioning of Caenorhabditis Elegans to Anoxic Insult by Inactivation of Cholinergic, GABAergic and Muscle Activity Genes, Brain, and Behavior. Apr, 2021 | Pubmed ID: 33155386 Sleep Induction by Mechanosensory Stimulation in Drosophila Cell Reports. Dec, 2020 | Pubmed ID: 33264620 Dehydrated Stocks Are Resistant to Multiple Freeze-Thaw Cycles G3 (Bethesda, Md.). Dec, 2020 | Pubmed ID: 33033066 A Quiescent State Following Mild Sensory Arousal in Caenorhabditis Elegans is Potentiated by Stress Scientific Reports. Mar, 2020 | Pubmed ID: 32139752 Optimized Criteria for Locomotion-based Healthspan Evaluation in C. elegans Using the WorMotel System PloS One. 2020 | Pubmed ID: 32126105 Quantitative Imaging of Sleep Behavior in Caenorhabditis Elegans and Larval Drosophila Melanogaster Nature Protocols. May, 2019 | Pubmed ID: 30953041 A Sleep State in Larvae Required for Neural Stem Cell Proliferation ELife. Feb, 2018 | Pubmed ID: 29424688 Distributed Rhythm Generators Underlie Forward Locomotion ELife. Jan, 2018 | Pubmed ID: 29360037 Excitatory Motor Neurons Are Local Oscillators for Backward Locomotion ELife. Jan, 2018 | Pubmed ID: 29360035 Comparing Caenorhabditis Elegans Gentle and Harsh Touch Response Behavior Using a Multiplexed Hydraulic Microfluidic Device Integrative Biology : Quantitative Biosciences from Nano to Macro. Oct, 2017 | Pubmed ID: 28914311 Antagonistic Serotonergic and Octopaminergic Neural Circuits Mediate Food-Dependent Locomotory Behavior in The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2017 | Pubmed ID: 28698386 Longitudinal Imaging of in a Microfabricated Device Reveals Variation in Behavioral Decline During Aging ELife. May, 2017 | Pubmed ID: 28537553 Quantitative Assessment of Fat Levels in Using Dark Field Microscopy G3 (Bethesda, Md.). Jun, 2017 | Pubmed ID: 28404661 Food Responsiveness Regulates Episodic Behavioral States in Journal of Neurophysiology. May, 2017 | Pubmed ID: 28228583 The RFamide Receptor DMSR-1 Regulates Stress-induced Sleep in ELife. Jan, 2017 | Pubmed ID: 28094002 Ageing with Elegans: a Research Proposal to Map Healthspan Pathways Biogerontology. Aug, 2016 | Pubmed ID: 27040825 Pharyngeal Pumping in Caenorhabditis Elegans Depends on Tonic and Phasic Signaling from the Nervous System Scientific Reports. Mar, 2016 | Pubmed ID: 26976078 Evidence for Novel Pharmacological Sensitivities of Transient Receptor Potential (TRP) Channels in Schistosoma Mansoni PLoS Neglected Tropical Diseases. Dec, 2015 | Pubmed ID: 26655809 Distinct Mechanisms Underlie Quiescence During Two Caenorhabditis Elegans Sleep-Like States The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2015 | Pubmed ID: 26511247 An Imaging System for C. Elegans Behavior Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 26423976 Simultaneous Optogenetic Stimulation of Individual Pharyngeal Neurons and Monitoring of Feeding Behavior in Intact C. Elegans Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 26423971 Altered Right Ventricular Kinetic Energy Work Density and Viscous Energy Dissipation in Patients with Pulmonary Arterial Hypertension: A Pilot Study Using 4D Flow MRI PloS One. 2015 | Pubmed ID: 26418553 Illuminating Neural Circuits and Behaviour in Caenorhabditis Elegans with Optogenetics Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Sep, 2015 | Pubmed ID: 26240427 Preferential Coupling of an Incident Wave to Reflection Eigenchannels of Disordered Media Scientific Reports. Jun, 2015 | Pubmed ID: 26078088 FMRFamide-like FLP-13 Neuropeptides Promote Quiescence Following Heat Stress in Caenorhabditis Elegans Current Biology : CB. Oct, 2014 | Pubmed ID: 25264253 Neural and Genetic Degeneracy Underlies Caenorhabditis Elegans Feeding Behavior Journal of Neurophysiology. Aug, 2014 | Pubmed ID: 24872529 Construction of a System for Single-cell Transgene Induction in Caenorhabditis Elegans Using a Pulsed Infrared Laser Methods (San Diego, Calif.). Aug, 2014 | Pubmed ID: 24835576 Multi-well Imaging of Development and Behavior in Caenorhabditis Elegans Journal of Neuroscience Methods. Feb, 2014 | Pubmed ID: 24321627 Efficient Single-cell Transgene Induction in Caenorhabditis Elegans Using a Pulsed Infrared Laser G3 (Bethesda, Md.). Oct, 2013 | Pubmed ID: 23979939 Long-term Imaging of Caenorhabditis Elegans Using Nanoparticle-mediated Immobilization PloS One. 2013 | Pubmed ID: 23301069 Scanner-free and Wide-field Endoscopic Imaging by Using a Single Multimode Optical Fiber Physical Review Letters. Nov, 2012 | Pubmed ID: 23215488 Proprioceptive Coupling Within Motor Neurons Drives C. Elegans Forward Locomotion Neuron. Nov, 2012 | Pubmed ID: 23177960 IRK-1 Potassium Channels Mediate Peptidergic Inhibition of Caenorhabditis Elegans Serotonin Neurons Via a G(o) Signaling Pathway The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2012 | Pubmed ID: 23152612 Laser Microsurgery in Caenorhabditis Elegans Methods in Cell Biology. 2012 | Pubmed ID: 22226524 Overcoming the Diffraction Limit Using Multiple Light Scattering in a Highly Disordered Medium Physical Review Letters. Jul, 2011 | Pubmed ID: 21797607 High-speed Synthetic Aperture Microscopy for Live Cell Imaging Optics Letters. Jan, 2011 | Pubmed ID: 21263482 Optogenetic Manipulation of Neural Activity in Freely Moving Caenorhabditis Elegans Nature Methods. Feb, 2011 | Pubmed ID: 21240279 Biomechanical Analysis of Gait Adaptation in the Nematode Caenorhabditis Elegans Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010 | Pubmed ID: 21048086 Long-Term Culture and Monitoring of Isolated Caenorhabditis elegans on Solid Media in Multi-Well Devices Emily A. Gardea1, Destiny DeNicola1, Samuel Freitas1, Will Peterson1, Hope Dang1, Karissa Shuck1, Christopher Fang-Yen2, George L. Sutphin1 1Department of Molecular & Cellular Biology, University of Arizona, 2Department of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania JoVE 64681 Biology
Long-Term Culture and Monitoring of Isolated Caenorhabditis elegans on Solid Media in Multi-Well Devices Emily A. Gardea1, Destiny DeNicola1, Samuel Freitas1, Will Peterson1, Hope Dang1, Karissa Shuck1, Christopher Fang-Yen2, George L. Sutphin1 1Department of Molecular & Cellular Biology, University of Arizona, 2Department of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania JoVE 64681 Biology
