Cindy Shu Raymond Purves Bone and Joint Research Laboratory, Institute of Bone and Joint Research, Kolling Institute, Royal North Shore Hospital University of Sydney Biography Publications Institution JoVE Articles Cindy Shu has not added a biography. If you are Cindy Shu and would like to personalize this page please email our Author Liaison for assistance. Publications The Relationship Between Synovial Inflammation, Structural Pathology, and Pain in Post-traumatic Osteoarthritis: Differential Effect of Stem Cell and Hyaluronan Treatment Arthritis Research & Therapy. 02, 2020 | Pubmed ID: 32059749 Spatiotemporal Expression of 3-B-3(-) and 7-D-4 Chondroitin Sulfation, Tissue Remodeling, and Attempted Repair in an Ovine Model of Intervertebral Disc Degeneration Cartilage. Apr, 2020 | Pubmed ID: 31578084 Catabolism of Fibromodulin in Developmental Rudiment and Pathologic Articular Cartilage Demonstrates Novel Roles for MMP-13 and ADAMTS-4 in C-terminal Processing of SLRPs International Journal of Molecular Sciences. Jan, 2019 | Pubmed ID: 30700002 Elevated Hypertrophy, Growth Plate Maturation, Glycosaminoglycan Deposition, and Exostosis Formation in the Exon 3 Null Mouse Intervertebral Disc The Biochemical Journal. 01, 2019 | Pubmed ID: 30563944 Efficacy of Administered Mesenchymal Stem Cells in the Initiation and Co-ordination of Repair Processes by Resident Disc Cells in an Ovine (Ovis Aries) Large Destabilizing Lesion Model of Experimental Disc Degeneration JOR Spine. Dec, 2018 | Pubmed ID: 31463452 Achilles and Tail Tendons of Perlecan Exon 3 Null Heparan Sulphate Deficient Mice Display Surprising Improvement in Tendon Tensile Properties and Altered Collagen Fibril Organisation Compared to C57BL/6 Wild Type Mice PeerJ. 2018 | Pubmed ID: 30042881 Macrophage Polarization Contributes to Local Inflammation and Structural Change in the Multifidus Muscle After Intervertebral Disc Injury European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 08, 2018 | Pubmed ID: 29948327 The Adolescent Idiopathic Scoliotic IVD Displays Advanced Aggrecanolysis and a Glycosaminoglycan Composition Similar to That of Aged Human and Ovine IVDs European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 09, 2018 | Pubmed ID: 29441417 Hyaluronan Oligosaccharides Stimulate Matrix Metalloproteinase and Anabolic Gene Expression in Vitro by Intervertebral Disc Cells and Annular Repair in Vivo Journal of Tissue Engineering and Regenerative Medicine. 01, 2018 | Pubmed ID: 27689852 A Histopathological Scheme for the Quantitative Scoring of Intervertebral Disc Degeneration and the Therapeutic Utility of Adult Mesenchymal Stem Cells for Intervertebral Disc Regeneration International Journal of Molecular Sciences. May, 2017 | Pubmed ID: 28498326 Use of FGF-2 and FGF-18 to Direct Bone Marrow Stromal Stem Cells to Chondrogenic and Osteogenic Lineages Future Science OA. Dec, 2016 | Pubmed ID: 28116125 Mesenchymal Stem Cell Treatment of Intervertebral Disc Lesion Prevents Fatty Infiltration and Fibrosis of the Multifidus Muscle, but Not Cytokine and Muscle Fiber Changes Spine. Aug, 2016 | Pubmed ID: 27135642 The Heparan Sulphate Deficient Hspg2 Exon 3 Null Mouse Displays Reduced Deposition of TGF-β1 in Skin Compared to C57BL/6 Wild Type Mice Journal of Molecular Histology. Jun, 2016 | Pubmed ID: 27098652 Allogeneic Mesenchymal Precursor Cells Promote Healing in Postero-lateral Annular Lesions and Improve Indices of Lumbar Intervertebral Disc Degeneration in an Ovine Model Spine. Sep, 2016 | Pubmed ID: 26913464 The Cartilage Extracellular Matrix As a Transient Developmental Scaffold for Growth Plate Maturation Matrix Biology : Journal of the International Society for Matrix Biology. May-Jul, 2016 | Pubmed ID: 26807757 Ablation of Perlecan Domain 1 Heparan Sulfate Reduces Progressive Cartilage Degradation, Synovitis, and Osteophyte Size in a Preclinical Model of Posttraumatic Osteoarthritis Arthritis & Rheumatology (Hoboken, N.J.). Apr, 2016 | Pubmed ID: 26636652 Multifidus Muscle Changes After Back Injury Are Characterized by Structural Remodeling of Muscle, Adipose and Connective Tissue, but Not Muscle Atrophy: Molecular and Morphological Evidence Spine. Jul, 2015 | Pubmed ID: 25943090 Confocal Microscopy Demonstrates Association of LTBP-2 in Fibrillin-1 Microfibrils and Colocalisation with Perlecan in the Disc Cell Pericellular Matrix Tissue & Cell. Jun, 2014 | Pubmed ID: 24867584 The Ovine Newborn and Human Foetal Intervertebral Disc Contain Perlecan and Aggrecan Variably Substituted with Native 7D4 CS Sulphation Motif: Spatiotemporal Immunolocalisation and Co-distribution with Notch-1 in the Human Foetal Disc Glycoconjugate Journal. Oct, 2013 | Pubmed ID: 23756834 Comparative Immunolocalisation of Perlecan, Heparan Sulphate, Fibroblast Growth Factor-18, and Fibroblast Growth Factor Receptor-3 and Their Prospective Roles in Chondrogenic and Osteogenic Development of the Human Foetal Spine European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. Aug, 2013 | Pubmed ID: 23397188 Mechanical Destabilization Induced by Controlled Annular Incision of the Intervertebral Disc Dysregulates Metalloproteinase Expression and Induces Disc Degeneration Spine. Jan, 2012 | Pubmed ID: 22179320 Flow Cytometry Analysis of Immune Cell Subsets within the Murine Spleen, Bone Marrow, Lymph Nodes and Synovial Tissue in an Osteoarthritis Model Patrick Haubruck1,2, Aimee C. Colbath1,3, Yolanda Liu1, Shihani Stoner1, Cindy Shu1, Christopher B. Little1 1Raymond Purves Bone and Joint Research Laboratory, Institute of Bone and Joint Research, Kolling Institute, Royal North Shore Hospital, University of Sydney, 2HTRG - Heidelberg Trauma Research Group, Center for Orthopedics, Trauma Surgery and Spinal Cord Injury, Trauma and Reconstructive Surgery, Heidelberg University Hospital, 3Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University JoVE 61008 Medicine
Flow Cytometry Analysis of Immune Cell Subsets within the Murine Spleen, Bone Marrow, Lymph Nodes and Synovial Tissue in an Osteoarthritis Model Patrick Haubruck1,2, Aimee C. Colbath1,3, Yolanda Liu1, Shihani Stoner1, Cindy Shu1, Christopher B. Little1 1Raymond Purves Bone and Joint Research Laboratory, Institute of Bone and Joint Research, Kolling Institute, Royal North Shore Hospital, University of Sydney, 2HTRG - Heidelberg Trauma Research Group, Center for Orthopedics, Trauma Surgery and Spinal Cord Injury, Trauma and Reconstructive Surgery, Heidelberg University Hospital, 3Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University JoVE 61008 Medicine
