Publications

• Muscle Dysfunction in Hypertrophic Cardiomyopathy: What is Needed to Move to Translation?
  Journal of Muscle Research and Cell Motility. Feb, 2014  |   Pubmed ID: 24493262
• Regulation of Intracellular Na(+) in Health and Disease: Pathophysiological Mechanisms and Implications for Treatment
  Global Cardiology Science & Practice. 2013  |   Pubmed ID: 24689024
• Clusters of Bound Ca(2+) Initiate Contraction in Fast Skeletal Muscle
  Archives of Biochemistry and Biophysics. Dec, 2013  |   Pubmed ID: 24374032
• Response to Letter Regarding Article, "Late Sodium Current Inhibition Reverses Electromechanical Dysfunction in Human Hypertrophic Cardiomyopathy"
  Circulation. Sep, 2013  |   Pubmed ID: 24002721
• Chronic Atrial Fibrillation Alters the Functional Properties of If in the Human Atrium
  Journal of Cardiovascular Electrophysiology. Dec, 2013  |   Pubmed ID: 23869794
• Deleting Exon 55 from the Nebulin Gene Induces Severe Muscle Weakness in a Mouse Model for Nemaline Myopathy
  Brain : a Journal of Neurology. Jun, 2013  |   Pubmed ID: 23715096
• Mutations in MYH7 Reduce the Force Generating Capacity of Sarcomeres in Human Familial Hypertrophic Cardiomyopathy
  Cardiovascular Research. Aug, 2013  |   Pubmed ID: 23674513
• Perturbed Length-dependent Activation in Human Hypertrophic Cardiomyopathy with Missense Sarcomeric Gene Mutations
  Circulation Research. May, 2013  |   Pubmed ID: 23508784
• Late Sodium Current Inhibition Reverses Electromechanical Dysfunction in Human Hypertrophic Cardiomyopathy
  Circulation. Feb, 2013  |   Pubmed ID: 23271797
• Tropomyosin Ser-283 Pseudo-phosphorylation Slows Myofibril Relaxation
  Archives of Biochemistry and Biophysics. Jul, 2013  |   Pubmed ID: 23232082
• α-Tropomyosin with a D175N or E180G Mutation in Only One Chain Differs from Tropomyosin with Mutations in Both Chains
  Biochemistry. Dec, 2012  |   Pubmed ID: 23170982
• Patterns of Disease Progression in Hypertrophic Cardiomyopathy: an Individualized Approach to Clinical Staging
  Circulation. Heart Failure. Jul, 2012  |   Pubmed ID: 22811549
• Action Potential Propagation in Transverse-axial Tubular System is Impaired in Heart Failure
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2012  |   Pubmed ID: 22451916
• Calcium Binding Kinetics of Troponin C Strongly Modulate Cooperative Activation and Tension Kinetics in Cardiac Muscle
  Journal of Molecular and Cellular Cardiology. Jan, 2011  |   Pubmed ID: 21035455
• Extraction and Replacement of the Tropomyosin-troponin Complex in Isolated Myofibrils
  Advances in Experimental Medicine and Biology. 2010  |   Pubmed ID: 20824525
• Effects of Chronic Atrial Fibrillation on Active and Passive Force Generation in Human Atrial Myofibrils
  Circulation Research. Jul, 2010  |   Pubmed ID: 20466979
• Susceptibility of Isolated Myofibrils to in Vitro Glutathionylation: Potential Relevance to Muscle Functions
  Cytoskeleton (Hoboken, N.J.). Feb, 2010  |   Pubmed ID: 20169532
• Mechanical and Energetic Consequences of HCM-causing Mutations
  Journal of Cardiovascular Translational Research. Dec, 2009  |   Pubmed ID: 20560002
• Developmental Origins of Hypertrophic Cardiomyopathy Phenotypes: a Unifying Hypothesis
  Nature Reviews. Cardiology. Apr, 2009  |   Pubmed ID: 19352336
• Insights into the Kinetics of Ca2+-regulated Contraction and Relaxation from Myofibril Studies
  Pflügers Archiv : European Journal of Physiology. Jun, 2009  |   Pubmed ID: 19165498
• The Familial Hypertrophic Cardiomyopathy-associated Myosin Mutation R403Q Accelerates Tension Generation and Relaxation of Human Cardiac Myofibrils
  The Journal of Physiology. Aug, 2008  |   Pubmed ID: 18565996
• Thin Filament Ca2+ Binding Properties and Regulatory Unit Interactions Alter Kinetics of Tension Development and Relaxation in Rabbit Skeletal Muscle
  The Journal of Physiology. Aug, 2008  |   Pubmed ID: 18535094
• Myofilament Protein Gene Mutation Screening and Outcome of Patients with Hypertrophic Cardiomyopathy
  Mayo Clinic Proceedings. Jun, 2008  |   Pubmed ID: 18533079
• Spatially-compressed Cardiac Myofilament Models Generate Hysteresis That is Not Found in Real Muscle
  Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 2008  |   Pubmed ID: 18229700
• Tension Generation and Relaxation in Single Myofibrils from Human Atrial and Ventricular Myocardium
  Pflügers Archiv : European Journal of Physiology. Apr, 2007  |   Pubmed ID: 17123098
• Myofilament Calcium Sensitivity Does Not Affect Cross-bridge Activation-relaxation Kinetics
  American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Mar, 2007  |   Pubmed ID: 17082350
• Impaired Diastolic Function After Exchange of Endogenous Troponin I with C-terminal Truncated Troponin I in Human Cardiac Muscle
  Circulation Research. Oct, 2006  |   Pubmed ID: 17023673
• Sarcomeric Determinants of Striated Muscle Relaxation Kinetics
  Pflügers Archiv : European Journal of Physiology. Mar, 2005  |   Pubmed ID: 15750836
• Relaxation Kinetics Following Sudden Ca(2+) Reduction in Single Myofibrils from Skeletal Muscle
  Biophysical Journal. Oct, 2002  |   Pubmed ID: 12324431