Cynthia C Bartholomae Department of Translational Oncology National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ) Biography Publications Institution JoVE Articles Cynthia C Bartholomae has not added a biography. If you are Cynthia C Bartholomae and would like to personalize this page please email our Author Liaison for assistance. Publications Decoding the Regulatory Landscape of Medulloblastoma Using DNA Methylation Sequencing Nature. May, 2014 | Pubmed ID: 24847876 Genome Sequencing of SHH Medulloblastoma Predicts Genotype-related Response to Smoothened Inhibition Cancer Cell. Mar, 2014 | Pubmed ID: 24651015 Transgenic Expression of Human Glial Cell Line-Derived Neurotrophic Factor from Integration-Deficient Lentiviral Vectors is Neuroprotective in a Rodent Model of Parkinson's Disease Human Gene Therapy. Apr, 2014 | Pubmed ID: 24635742 Integration-deficient Lentiviral Vectors Expressing Codon-optimized R338L Human FIX Restore Normal Hemostasis in Hemophilia B Mice Molecular Therapy : the Journal of the American Society of Gene Therapy. Mar, 2014 | Pubmed ID: 23941813 Recurrent Somatic Alterations of FGFR1 and NTRK2 in Pilocytic Astrocytoma Nature Genetics. Aug, 2013 | Pubmed ID: 23817572 Integrative Genomic Analyses Reveal an Androgen-driven Somatic Alteration Landscape in Early-onset Prostate Cancer Cancer Cell. Feb, 2013 | Pubmed ID: 23410972 Lentiviral Vector-based Insertional Mutagenesis Identifies Genes Associated with Liver Cancer Nature Methods. Feb, 2013 | Pubmed ID: 23314173 Comparative Clonal Analysis of Reconstitution Kinetics After Transplantation of Hematopoietic Stem Cells Gene Marked with a Lentiviral SIN or a γ-retroviral LTR Vector Experimental Hematology. Jan, 2013 | Pubmed ID: 22989760 Preclinical Safety and Efficacy of Human CD34(+) Cells Transduced with Lentiviral Vector for the Treatment of Wiskott-Aldrich Syndrome Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2013 | Pubmed ID: 22371846 Dissecting the Genomic Complexity Underlying Medulloblastoma Nature. Aug, 2012 | Pubmed ID: 22832583 Bioinformatic Clonality Analysis of Next-generation Sequencing-derived Viral Vector Integration Sites Human Gene Therapy Methods. Apr, 2012 | Pubmed ID: 22559057 Insertion Site Pattern: Global Approach by Linear Amplification-mediated PCR and Mass Sequencing Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22367877 Lentiviral Hematopoietic Cell Gene Therapy for X-linked Adrenoleukodystrophy Methods in Enzymology. 2012 | Pubmed ID: 22365775 Analyzing the Number of Common Integration Sites of Viral Vectors--new Methods and Computer Programs PloS One. 2011 | Pubmed ID: 22022353 Retroviral Gene Therapy for X-linked Chronic Granulomatous Disease: Results from Phase I/II Trial Molecular Therapy : the Journal of the American Society of Gene Therapy. Nov, 2011 | Pubmed ID: 21878903 Insertion Sites in Engrafted Cells Cluster Within a Limited Repertoire of Genomic Areas After Gammaretroviral Vector Gene Therapy Molecular Therapy : the Journal of the American Society of Gene Therapy. Nov, 2011 | Pubmed ID: 21862999 An Unbiased Genome-wide Analysis of Zinc-finger Nuclease Specificity Nature Biotechnology. Sep, 2011 | Pubmed ID: 21822255 Stem Cell Gene Therapy for Fanconi Anemia: Report from the 1st International Fanconi Anemia Gene Therapy Working Group Meeting Molecular Therapy : the Journal of the American Society of Gene Therapy. Jul, 2011 | Pubmed ID: 21540837 Hepatocyte-targeted Expression by Integrase-defective Lentiviral Vectors Induces Antigen-specific Tolerance in Mice with Low Genotoxic Risk Hepatology (Baltimore, Md.). May, 2011 | Pubmed ID: 21520180 Lentiviral Vector Integration Profiles Differ in Rodent Postmitotic Tissues Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2011 | Pubmed ID: 21364536 Genome-wide High-throughput Integrome Analyses by NrLAM-PCR and Next-generation Sequencing Nature Protocols. Aug, 2010 | Pubmed ID: 20671722 Comprehensive Genomic Access to Vector Integration in Clinical Gene Therapy Nature Medicine. Dec, 2009 | Pubmed ID: 19966782 Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-linked Adrenoleukodystrophy Science (New York, N.Y.). Nov, 2009 | Pubmed ID: 19892975 The Genotoxic Potential of Retroviral Vectors is Strongly Modulated by Vector Design and Integration Site Selection in a Mouse Model of HSC Gene Therapy The Journal of Clinical Investigation. Apr, 2009 | Pubmed ID: 19307726 Detection of Retroviral Integration Sites by Linear Amplification-mediated PCR and Tracking of Individual Integration Clones in Different Samples Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19110638 Linear Amplification Mediated PCR - Lokalisering av genetiske elementer og karakterisering av Unknown flankerer DNA Richard Gabriel1, Ina Kutschera1, Cynthia C Bartholomae1, Christof von Kalle1, Manfred Schmidt1 1Department of Translational Oncology, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ) JoVE 51543 Biology
Linear Amplification Mediated PCR - Lokalisering av genetiske elementer og karakterisering av Unknown flankerer DNA Richard Gabriel1, Ina Kutschera1, Cynthia C Bartholomae1, Christof von Kalle1, Manfred Schmidt1 1Department of Translational Oncology, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ) JoVE 51543 Biology
