Dagmar Wirth Helmholtz Center for Infection Research Biography Publications Institution JoVE Articles Dagmar Wirth has not added a biography. If you are Dagmar Wirth and would like to personalize this page please email our Author Liaison for assistance. Publications Diet Induced Obesity Has an Influence on Intrahepatic T Cell Responses Metabolism: Clinical and Experimental. Apr, 2017 | Pubmed ID: 28285647 Proliferation Status Defines Functional Properties of Endothelial Cells Cellular and Molecular Life Sciences : CMLS. Apr, 2017 | Pubmed ID: 27853834 Epigenetic Modulations Rendering Cell-to-cell Variability and Phenotypic Metastability Journal of Genetics and Genomics = Yi Chuan Xue Bao. Aug, 2016 | Pubmed ID: 27569397 P120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification PLoS Genetics. Aug, 2016 | Pubmed ID: 27556156 Evaluation of the Inflammatory Potential of Implant Materials in a Mouse Model by Bioluminescent Imaging of Intravenously Injected Bone Marrow Cells Journal of Biomedical Materials Research. Part A. Sep, 2016 | Pubmed ID: 27102724 Human Alveolar Epithelial Cells Expressing Tight Junctions to Model the Air-blood Barrier ALTEX. 2016 | Pubmed ID: 26985677 Extracellular-signal Regulated Kinase (Erk1/2), Mitogen-activated Protein Kinase-activated Protein Kinase 2 (MK2) and Tristetraprolin (TTP) Comprehensively Regulate Injury-induced Immediate Early Gene (IEG) Response in in Vitro Liver Organ Culture Cellular Signalling. May, 2016 | Pubmed ID: 26876787 Impaired Antiviral Response of Adenovirus-transformed Cell Lines Supports Virus Replication The Journal of General Virology. Feb, 2016 | Pubmed ID: 26647282 Evidence That Hepatitis B Virus Replication in Mouse Cells is Limited by the Lack of a Host Cell Dependency Factor Journal of Hepatology. Mar, 2016 | Pubmed ID: 26576481 Effective Intrahepatic CD8+ T-cell Immune Responses Are Induced by Low but Not High Numbers of Antigen-expressing Hepatocytes Cellular & Molecular Immunology. Nov, 2016 | Pubmed ID: 26412123 A Permanently Growing Human Endothelial Cell Line Supports Productive Infection with Human Cytomegalovirus Under Conditional Cell Growth Arrest BioTechniques. Sep, 2015 | Pubmed ID: 26345505 Single-cell Analysis Reveals Heterogeneity in Onset of Transgene Expression from Synthetic Tetracycline-dependent Promoters Biotechnology Journal. Feb, 2015 | Pubmed ID: 25582352 Stability of Single Copy Transgene Expression in CHOK1 Cells is Affected by Histone Modifications but Not by DNA Methylation Journal of Biotechnology. Feb, 2015 | Pubmed ID: 25533398 Uncoupling of the Dynamics of Host-pathogen Interaction Uncovers New Mechanisms of Viral Interferon Antagonism at the Single-cell Level Nucleic Acids Research. Jul, 2014 | Pubmed ID: 24895433 Reversible Silencing of Cytomegalovirus Genomes by Type I Interferon Governs Virus Latency PLoS Pathogens. Feb, 2014 | Pubmed ID: 24586165 Efficient ROSA26-based Conditional And/or Inducible Transgenesis Using RMCE-compatible F1 Hybrid Mouse Embryonic Stem Cells Stem Cell Reviews. Dec, 2013 | Pubmed ID: 23877658 An Inducible Transgenic Mouse Model for Immune Mediated Hepatitis Showing Clearance of Antigen Expressing Hepatocytes by CD8+ T Cells PloS One. 2013 | Pubmed ID: 23869228 Eternity and Functionality - Rational Access to Physiologically Relevant Cell Lines Biological Chemistry. Dec, 2013 | Pubmed ID: 23863696 A New Reporter Mouse Cytomegalovirus Reveals Maintained Immediate-early Gene Expression but Poor Virus Replication in Cycling Liver Sinusoidal Endothelial Cells Virology Journal. Jun, 2013 | Pubmed ID: 23773211 The ROSA26-iPSC Mouse: a Conditional, Inducible, and Exchangeable Resource for Studying Cellular (De)differentiation Cell Reports. Feb, 2013 | Pubmed ID: 23395636 Towards Rational Engineering of Cells: Recombinant Gene Expression in Defined Chromosomal Loci BMC Proceedings. 2011 | Pubmed ID: 22373348 Streamlining Homogeneous Glycoprotein Production for Biophysical and Structural Applications by Targeted Cell Line Development PloS One. 2011 | Pubmed ID: 22174749 Deletion of Kaposi's Sarcoma-associated Herpesvirus FLICE Inhibitory Protein, VFLIP, from the Viral Genome Compromises the Activation of STAT1-responsive Cellular Genes and Spindle Cell Formation in Endothelial Cells Journal of Virology. Oct, 2011 | Pubmed ID: 21795355 Manufacturing of Retroviruses Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21590397 Lentivirus Production is Influenced by SV40 Large T-antigen and Chromosomal Integration of the Vector in HEK293 Cells Human Gene Therapy. Oct, 2011 | Pubmed ID: 21554103 Rapid Establishment of G-protein-coupled Receptor-expressing Cell Lines by Site-specific Integration Journal of Biomolecular Screening. Mar, 2011 | Pubmed ID: 21335600 Integrated Strategy for the Production of Therapeutic Retroviral Vectors Human Gene Therapy. Mar, 2011 | Pubmed ID: 21043806 Precise Regulation of Transgene Expression Level and Control of Cell Physiology Cell Biology and Toxicology. Feb, 2010 | Pubmed ID: 19763851 Synthetic Gene Regulation Circuits for Control of Cell Expansion Tissue Engineering. Part A. Feb, 2010 | Pubmed ID: 19705962 Recombinant Protein Expression by Targeting Pre-selected Chromosomal Loci BMC Biotechnology. Dec, 2009 | Pubmed ID: 20003421 Bimodal and Hysteretic Expression in Mammalian Cells from a Synthetic Gene Circuit PloS One. Jun, 2008 | Pubmed ID: 18523635 In Vitro Expansion of Tissue Cells by Conditional Proliferation Methods in Molecular Medicine. 2007 | Pubmed ID: 18085200 Road to Precision: Recombinase-based Targeting Technologies for Genome Engineering Current Opinion in Biotechnology. Oct, 2007 | Pubmed ID: 17904350 Current Status of Transcriptional Regulation Systems Cytotechnology. Mar, 2006 | Pubmed ID: 19003074 Health Status of Transgenic Pigs Expressing the Human Complement Regulatory Protein CD59 Xenotransplantation. Jul, 2006 | Pubmed ID: 16768728 A New Generation of Retroviral Producer Cells: Predictable and Stable Virus Production by Flp-mediated Site-specific Integration of Retroviral Vectors Molecular Therapy : the Journal of the American Society of Gene Therapy. Aug, 2006 | Pubmed ID: 16697259 Epigenetic Silencing and Tissue Independent Expression of a Novel Tetracycline Inducible System in Double-transgenic Pigs FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2006 | Pubmed ID: 16684801 Establishment of Murine Cell Lines by Constitutive and Conditional Immortalization Journal of Biotechnology. Oct, 2005 | Pubmed ID: 16026879 Simultaneous Blockade of NFkappaB, JNK, and P38 MAPK by a Kinase-inactive Mutant of the Protein Kinase TAK1 Sensitizes Cells to Apoptosis and Affects a Distinct Spectrum of Tumor Necrosis Factor [corrected] Target Genes The Journal of Biological Chemistry. Jul, 2005 | Pubmed ID: 15837794 Transcriptionally Regulated Immortalization Overcomes Side Effects of Temperature-sensitive SV40 Large T Antigen Biochemical and Biophysical Research Communications. Feb, 2005 | Pubmed ID: 15649408 Application of a Reversible Immortalization System for the Generation of Proliferation-controlled Cell Lines Cytotechnology. Oct, 2004 | Pubmed ID: 19003263 Transcriptional Control of SV40 T-antigen Expression Allows a Complete Reversion of Immortalization Nucleic Acids Research. 2004 | Pubmed ID: 15486202 Interleukin-6 is a Direct Mediator of T Cell Migration European Journal of Immunology. Oct, 2004 | Pubmed ID: 15368306 Flp-mediated Integration of Expression Cassettes into FRT-tagged Chromosomal Loci in Mammalian Cells Methods in Molecular Biology (Clifton, N.J.). 2004 | Pubmed ID: 15269443 Stable and Strictly Controlled Expression of LTR-flanked Autoregulated Expression Cassettes Upon Adenoviral Transfer Biochemical and Biophysical Research Communications. Jul, 2004 | Pubmed ID: 15184065 Green Fluorescent Protein-tagged Retroviral Envelope Protein for Analysis of Virus-cell Interactions Journal of Virology. May, 2003 | Pubmed ID: 12719600 リコンビナーゼ媒介カセット交換を用いて、マウス胚性幹細胞における構造と機能の研究 Tim Pieters1,2,3,4, Lieven Haenebalcke1,2, Kenneth Bruneel1,2,4, Niels Vandamme1,2,4, Tino Hochepied1,2, Jolanda van Hengel5, Dagmar Wirth6, Geert Berx1,2,4, Jody J. Haigh7, Frans van Roy1,2,4, Steven Goossens1,2,3,4 1Department of Biomedical Molecular Biology, Ghent University, 2Inflammation Research Center, VIB, 3Center for Medical Genetics, Ghent University Hospital, 4Cancer Research Institute Ghent (CRIG), 5Department of Basic Medical Sciences, Faculty of Medicine and Health Sciences, Ghent University, 6Helmholtz Center for Infection Research, 7Mammalian Functional Genetics Laboratory, Division of Blood Cancers, Australian Centre for Blood Diseases, Department of Clinical Haematology, Monash University and Alfred Health Alfred Centre JoVE 55575 Developmental Biology
リコンビナーゼ媒介カセット交換を用いて、マウス胚性幹細胞における構造と機能の研究 Tim Pieters1,2,3,4, Lieven Haenebalcke1,2, Kenneth Bruneel1,2,4, Niels Vandamme1,2,4, Tino Hochepied1,2, Jolanda van Hengel5, Dagmar Wirth6, Geert Berx1,2,4, Jody J. Haigh7, Frans van Roy1,2,4, Steven Goossens1,2,3,4 1Department of Biomedical Molecular Biology, Ghent University, 2Inflammation Research Center, VIB, 3Center for Medical Genetics, Ghent University Hospital, 4Cancer Research Institute Ghent (CRIG), 5Department of Basic Medical Sciences, Faculty of Medicine and Health Sciences, Ghent University, 6Helmholtz Center for Infection Research, 7Mammalian Functional Genetics Laboratory, Division of Blood Cancers, Australian Centre for Blood Diseases, Department of Clinical Haematology, Monash University and Alfred Health Alfred Centre JoVE 55575 Developmental Biology