Dale F. Mierke Department of Chemistry Dartmouth College Biography Publications Institution JoVE Articles Dale F. Mierke has not added a biography. If you are Dale F. Mierke and would like to personalize this page please email our Author Liaison for assistance. Publications The IKK-binding Domain of NEMO is an Irregular Coiled Coil with a Dynamic Binding Interface Scientific Reports. Feb, 2019 | Pubmed ID: 30814588 The Peach RGF/GLV Signaling Peptide PCTG134 Is Involved in a Regulatory Circuit That Sustains Auxin and Ethylene Actions Frontiers in Plant Science. 2017 | Pubmed ID: 29075273 Modulating the Dysregulated Migration of Pulmonary Arterial Hypertensive Smooth Muscle Cells with Motif Mimicking Cell Permeable Peptides Current Topics in Peptide & Protein Research. 2015 | Pubmed ID: 27274622 Identification and Characterization of the Interaction Site Between CFLIPL and Calmodulin PloS One. 2015 | Pubmed ID: 26529318 Assembly and Turnover of Short Actin Filaments by the Formin INF2 and Profilin The Journal of Biological Chemistry. Sep, 2015 | Pubmed ID: 26124273 New Monocyclic, Bicyclic, and Tricyclic Ethynylcyanodienones As Activators of the Keap1/Nrf2/ARE Pathway and Inhibitors of Inducible Nitric Oxide Synthase Journal of Medicinal Chemistry. Jun, 2015 | Pubmed ID: 25965897 A Novel Caspase 8 Selective Small Molecule Potentiates TRAIL-induced Cell Death Scientific Reports. May, 2015 | Pubmed ID: 25962125 Small-molecule Inhibitors of JC Polyomavirus Infection Journal of Peptide Science : an Official Publication of the European Peptide Society. Mar, 2015 | Pubmed ID: 25522925 Phosphorylation of Ezrin-radixin-moesin-binding Phosphoprotein 50 (EBP50) by Akt Promotes Stability and Mitogenic Function of S-phase Kinase-associated Protein-2 (Skp2) The Journal of Biological Chemistry. Jan, 2015 | Pubmed ID: 25492869 Computational Design of Selective Peptides to Discriminate Between Similar PDZ Domains in an Oncogenic Pathway Journal of Molecular Biology. Jan, 2015 | Pubmed ID: 25451599 Protein Engineering of the N-terminus of NEMO: Structure Stabilization and Rescue of IKKβ Binding Biochemistry. Nov, 2014 | Pubmed ID: 25286246 Small Molecule Inhibition of the Na(+)/H(+) Exchange Regulatory Factor 1 and Parathyroid Hormone 1 Receptor Interaction Biochemistry. Sep, 2014 | Pubmed ID: 25171053 Monitoring ATP Hydrolysis and ATPase Inhibitor Screening Using (1)H NMR Chemical Communications (Cambridge, England). Oct, 2014 | Pubmed ID: 25170530 Gallic Acid-based Small-molecule Inhibitors of JC and BK Polyomaviral Infection Virus Research. Aug, 2014 | Pubmed ID: 24960120 Engineering a Soluble Parathyroid Hormone GPCR Mimetic Proteins. Jul, 2014 | Pubmed ID: 24375686 Recombinant Production of TEV Cleaved Human Parathyroid Hormone Journal of Peptide Science : an Official Publication of the European Peptide Society. Aug, 2013 | Pubmed ID: 23794508 C-terminus of ETA/ETB Receptors Regulate Endothelin-1 Signal Transmission Journal of Peptide Science : an Official Publication of the European Peptide Society. Apr, 2013 | Pubmed ID: 23436727 Ligand Binding Site Identification by Higher Dimension Molecular Dynamics Journal of Chemical Information and Modeling. Mar, 2013 | Pubmed ID: 23394112 Reining in Polyoma Virus Associated Nephropathy: Design and Characterization of a Template Mimicking BK Viral Coat Protein Cellular Binding Biochemistry. Oct, 2012 | Pubmed ID: 23002929 An Exceptionally Potent Inducer of Cytoprotective Enzymes: Elucidation of the Structural Features That Determine Inducer Potency and Reactivity with Keap1 The Journal of Biological Chemistry. Oct, 2010 | Pubmed ID: 20801881 Hydrophobic Residues in Helix 8 of Cannabinoid Receptor 1 Are Critical for Structural and Functional Properties Biochemistry. Jan, 2010 | Pubmed ID: 20025243 Dual Role of the Second Extracellular Loop of the Cannabinoid Receptor 1: Ligand Binding and Receptor Localization Molecular Pharmacology. Oct, 2009 | Pubmed ID: 19643997 Structural Analysis of the Human Cannabinoid Receptor One Carboxyl-terminus Identifies Two Amphipathic Helices Biopolymers. Jul, 2009 | Pubmed ID: 19274719 PTH and PTH Antagonist Induce Different Conformational Changes in the PTHR1 Receptor Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. May, 2009 | Pubmed ID: 19063682 Residue 17 of Sauvagine Cross-links to the First Transmembrane Domain of Corticotropin-releasing Factor Receptor 1 (CRFR1) The Journal of Biological Chemistry. Dec, 2008 | Pubmed ID: 18955489 Phosphorylation-dependent Trafficking of GluR2-containing AMPA Receptors in the Nucleus Accumbens Plays a Critical Role in the Reinstatement of Cocaine Seeking The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2008 | Pubmed ID: 18945913 Mapping Peptide Hormone-receptor Interactions Using a Disulfide-trapping Approach Biochemistry. Jun, 2008 | Pubmed ID: 18459800 Mapping Ligand-receptor Interfaces: Approaching the Resolution Limit of Benzophenone-based Photoaffinity Scanning Chemical Biology & Drug Design. Apr, 2008 | Pubmed ID: 18312550 Conformational Changes in the Parathyroid Hormone Receptor Associated with Activation by Agonist Molecular Endocrinology (Baltimore, Md.). May, 2008 | Pubmed ID: 18258686 NEMO'nun IKK bağlayıcı alanının üretimi, kristalizasyonu ve Yapı Tayini Adam H. Barczewski1, Michael J. Ragusa1, Dale F. Mierke1, Maria Pellegrini1 1Department of Chemistry, Dartmouth College JoVE 60339 Biochemistry
NEMO'nun IKK bağlayıcı alanının üretimi, kristalizasyonu ve Yapı Tayini Adam H. Barczewski1, Michael J. Ragusa1, Dale F. Mierke1, Maria Pellegrini1 1Department of Chemistry, Dartmouth College JoVE 60339 Biochemistry