Dan S. Kaufman Department of Medicine (Hematology, Oncology, and Transplant) University of Minnesota, Minneapolis Biography Publications Institution JoVE Articles Dan S. Kaufman has not added a biography. If you are Dan S. Kaufman and would like to personalize this page please email our Author Liaison for assistance. Publications Clinical-scale Derivation of Natural Killer Cells from Human Pluripotent Stem Cells for Cancer Therapy Stem Cells Translational Medicine. Apr, 2013 | Pubmed ID: 23515118 Tu-mor(e) Blood Cells from Human Pluripotent Stem Cells Blood. Feb, 2013 | Pubmed ID: 23429981 Engineered Human Embryonic Stem Cell-Derived Lymphocytes to Study In Vivo Trafficking and Immunotherapy Stem Cells and Development. Mar, 2013 | Pubmed ID: 23421330 RUNX1a Enhances Hematopoietic Lineage Commitment from Human Embryonic Stem Cells and Inducible Pluripotent Stem Cells Blood. Apr, 2013 | Pubmed ID: 23372166 Functional Consequences of Human Induced Pluripotent Stem Cell Therapy: Myocardial ATP Turnover Rate in the in Vivo Swine Heart with Postinfarction Remodeling Circulation. Mar, 2013 | Pubmed ID: 23371930 Pluripotent Stem Cells and Gene Therapy Translational Research : the Journal of Laboratory and Clinical Medicine. Apr, 2013 | Pubmed ID: 23353080 Bioenergetic and Functional Consequences of Cellular Therapy: Activation of Endogenous Cardiovascular Progenitor Cells Circulation Research. Aug, 2012 | Pubmed ID: 22723295 Concise Review: Cord Blood Banking, Transplantation and Induced Pluripotent Stem Cell: Success and Opportunities Stem Cells (Dayton, Ohio). Jan, 2012 | Pubmed ID: 22069231 Extramedullary Relapse of Acute Myelogenous Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation: Better Prognosis Than Systemic Relapse Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Jan, 2012 | Pubmed ID: 21703975 Erythroid-specific Expression of β-globin from Sleeping Beauty-transduced Human Hematopoietic Progenitor Cells PloS One. 2011 | Pubmed ID: 22216176 Targeting Tumor-initiating Cancer Cells with DCD133KDEL Shows Impressive Tumor Reductions in a Xenotransplant Model of Human Head and Neck Cancer Molecular Cancer Therapeutics. Oct, 2011 | Pubmed ID: 21862685 In Vivo Evaluation of Putative Hematopoietic Stem Cells Derived from Human Pluripotent Stem Cells Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21822894 A Synthetic Substrate to Support Early Mesodermal Differentiation of Human Embryonic Stem Cells Biomaterials. Nov, 2011 | Pubmed ID: 21821284 A Fibrin Patch-based Enhanced Delivery of Human Embryonic Stem Cell-derived Vascular Cell Transplantation in a Porcine Model of Postinfarction Left Ventricular Remodeling Stem Cells (Dayton, Ohio). Feb, 2011 | Pubmed ID: 21732493 Induction of Fracture Repair by Mesenchymal Cells Derived from Human Embryonic Stem Cells or Bone Marrow Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Dec, 2011 | Pubmed ID: 21674605 Human Pluripotent Stem Cells Produce Natural Killer Cells That Mediate Anti-HIV-1 Activity by Utilizing Diverse Cellular Mechanisms Journal of Virology. Jan, 2011 | Pubmed ID: 20962093 Methotrexate Supports in Vivo Selection of Human Embryonic Stem Cell Derived-hematopoietic Cells Expressing Dihydrofolate Reductase Bioengineered Bugs. Nov-Dec, 2010 | Pubmed ID: 21468213 HIF Hits Wnt in the Stem Cell Niche Nature Cell Biology. Oct, 2010 | Pubmed ID: 20885419 Pluripotent Stem Cell-derived Natural Killer Cells for Cancer Therapy Translational Research : the Journal of Laboratory and Clinical Medicine. Sep, 2010 | Pubmed ID: 20801411 Human Embryonic Stem Cell-derived CD34+ Cells Function As MSC Progenitor Cells Bone. Oct, 2010 | Pubmed ID: 20601304 Use of Human Embryonic Stem Cells to Understand Hematopoiesis and Hematopoietic Stem Cell Niche Current Stem Cell Research & Therapy. Sep, 2010 | Pubmed ID: 20214557 Human Embryonic Stem Cell-derived Vascular Progenitor Cells Capable of Endothelial and Smooth Muscle Cell Function Experimental Hematology. Mar, 2010 | Pubmed ID: 20067819 Bioluminescent Imaging Demonstrates That Transplanted Human Embryonic Stem Cell-derived CD34(+) Cells Preferentially Develop into Endothelial Cells Stem Cells (Dayton, Ohio). Nov, 2009 | Pubmed ID: 19711457 Toward Clinical Therapies Using Hematopoietic Cells Derived from Human Pluripotent Stem Cells Blood. Oct, 2009 | Pubmed ID: 19652198 Myeloablative Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia: Analysis of Graft Sources and Long-term Outcome Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Aug, 2009 | Pubmed ID: 19581540 Human Embryonic Stem Cells Differentiate into a Homogeneous Population of Natural Killer Cells with Potent in Vivo Antitumor Activity Blood. Jun, 2009 | Pubmed ID: 19365083 Hematopoietic Differentiation of Human Embryonic Stem Cells by Cocultivation with Stromal Layers Current Protocols in Stem Cell Biology. Sep, 2008 | Pubmed ID: 18819084 Differences in Lymphocyte Developmental Potential Between Human Embryonic Stem Cell and Umbilical Cord Blood-derived Hematopoietic Progenitor Cells Blood. Oct, 2008 | Pubmed ID: 18621931 Differentiation of Embryonic Stem Cells Towards Hematopoietic Cells: Progress and Pitfalls Current Opinion in Hematology. Jul, 2008 | Pubmed ID: 18536568 Activation of Hypoxic Response in Human Embryonic Stem Cell-derived Embryoid Bodies Experimental Biology and Medicine (Maywood, N.J.). Aug, 2008 | Pubmed ID: 18535160 Selective POTE Paralogs on Chromosome 2 Are Expressed in Human Embryonic Stem Cells Stem Cells and Development. Apr, 2008 | Pubmed ID: 18447647 Hematopoietic Development of Human Embryonic Stem Cells in Culture Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18370295 Reduced-intensity Allogeneic Transplant in Patients Older Than 55 Years: Unrelated Umbilical Cord Blood is Safe and Effective for Patients Without a Matched Related Donor Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Mar, 2008 | Pubmed ID: 18275894 Wnt Signaling Promotes Hematoendothelial Cell Development from Human Embryonic Stem Cells Blood. Jan, 2008 | Pubmed ID: 17875805 Efficient and Stable Transgene Expression in Human Embryonic Stem Cells Using Transposon-mediated Gene Transfer Stem Cells (Dayton, Ohio). Nov, 2007 | Pubmed ID: 17673526 Donor Cell Leukemia: Insight into Cancer Stem Cells and the Stem Cell Niche Blood. Apr, 2007 | Pubmed ID: 17132724 Derivation of Normal Macrophages from Human Embryonic Stem (hES) Cells for Applications in HIV Gene Therapy Retrovirology. 2006 | Pubmed ID: 16623949 Improved Development of Human Embryonic Stem Cell-derived Embryoid Bodies by Stirred Vessel Cultivation Biotechnology and Bioengineering. Aug, 2006 | Pubmed ID: 16547998 Hematopoietic Engraftment of Human Embryonic Stem Cell-derived Cells is Regulated by Recipient Innate Immunity Stem Cells (Dayton, Ohio). May, 2006 | Pubmed ID: 16456127 Human Embryonic Stem Cell-derived Hematopoietic Cells Are Capable of Engrafting Primary As Well As Secondary Fetal Sheep Recipients Blood. Mar, 2006 | Pubmed ID: 16278307 Defined Conditions for Development of Functional Hepatic Cells from Human Embryonic Stem Cells Stem Cells and Development. Dec, 2005 | Pubmed ID: 16433619 Differentiation of Human Embryonic Stem Cells into Hematopoietic Cells by Coculture with Human Fetal Liver Cells Recapitulates the Globin Switch That Occurs Early in Development Experimental Hematology. Dec, 2005 | Pubmed ID: 16338487 Human Embryonic Stem Cell-derived NK Cells Acquire Functional Receptors and Cytolytic Activity Journal of Immunology (Baltimore, Md. : 1950). Oct, 2005 | Pubmed ID: 16210613 Nonhuman Primate Embryonic Stem Cells As a Preclinical Model for Hematopoietic and Vascular Repair Experimental Hematology. Sep, 2005 | Pubmed ID: 16140145 Synergistic Use of Adult and Embryonic Stem Cells to Study Human Hematopoiesis Current Opinion in Biotechnology. Oct, 2005 | Pubmed ID: 16095900 Hematopoietic Development of Human Embryonic Stem Cells in Culture Methods in Molecular Medicine. 2005 | Pubmed ID: 15492412 Hematopoietic Development of Human Embryonic Stem Cells in Culture Methods in Molecular Biology (Clifton, N.J.). 2005 | Pubmed ID: 15361661 Cytokine Requirements Differ for Stroma and Embryoid Body-mediated Hematopoiesis from Human Embryonic Stem Cells Experimental Hematology. Oct, 2004 | Pubmed ID: 15504555 Efficient Transfection of Embryonic and Adult Stem Cells Stem Cells (Dayton, Ohio). 2004 | Pubmed ID: 15277699 Functional Endothelial Cells Derived from Rhesus Monkey Embryonic Stem Cells Blood. Feb, 2004 | Pubmed ID: 14563647 Mouse and Human Embryonic Stem Cell Models of Hematopoiesis: Past, Present, and Future BioTechniques. Dec, 2003 | Pubmed ID: 14682061 Development, Expansion, and In vivo Monitoring of Human NK Cells from Human Embryonic Stem Cells (hESCs) and Induced Pluripotent Stem Cells (iPSCs) Allison M. Bock*1,2, David Knorr*1,2, Dan S. Kaufman1,2 1Department of Medicine (Hematology, Oncology, and Transplant), University of Minnesota, Minneapolis, 2Stem Cell Institute, University of Minnesota, Minneapolis JoVE 50337 Bioengineering
Development, Expansion, and In vivo Monitoring of Human NK Cells from Human Embryonic Stem Cells (hESCs) and Induced Pluripotent Stem Cells (iPSCs) Allison M. Bock*1,2, David Knorr*1,2, Dan S. Kaufman1,2 1Department of Medicine (Hematology, Oncology, and Transplant), University of Minnesota, Minneapolis, 2Stem Cell Institute, University of Minnesota, Minneapolis JoVE 50337 Bioengineering