Daniel E. Kaufmann The Ragon Institute of MGH, MIT and Harvard Biography Publications Institution JoVE Articles Daniel E. Kaufmann has not added a biography. If you are Daniel E. Kaufmann and would like to personalize this page please email our Author Liaison for assistance. Publications Simultaneous TCR and CD244 Signals Induce Dynamic Downmodulation of CD244 on Human Antiviral T Cells Journal of Immunology (Baltimore, Md. : 1950). Sep, 2013 | Pubmed ID: 23913963 Cutting Edge: Prolonged Exposure to HIV Reinforces a Poised Epigenetic Program for PD-1 Expression in Virus-specific CD8 T Cells Journal of Immunology (Baltimore, Md. : 1950). Jul, 2013 | Pubmed ID: 23772031 High-dimensional Immunomonitoring Models of HIV-1-specific CD8 T-cell Responses Accurately Identify Subjects Achieving Spontaneous Viral Control Blood. Jan, 2013 | Pubmed ID: 23233659 A Blueprint for HIV Vaccine Discovery Cell Host & Microbe. Oct, 2012 | Pubmed ID: 23084910 TCR Clonotypes Modulate the Protective Effect of HLA Class I Molecules in HIV-1 Infection Nature Immunology. Jul, 2012 | Pubmed ID: 22683743 CD4 + CD25 + Cellule T Regolatorie Compromettere Le Risposte Delle Cellule T CD4 HIV-1-specifiche Di Produzione Di Interleuchina-10 Upregulating Nei Monociti Journal of Virology. Jun, 2012 | Pubmed ID: 22496237 Conservata La Funzione Delle Cellule T Regolatorie Nell'infezione Cronica Da HIV-1, Nonostante I Numeri Diminuiti Nel Sangue E Nel Tessuto The Journal of Infectious Diseases. May, 2012 | Pubmed ID: 22427677 Role of PD-1 in HIV Pathogenesis and As Target for Therapy Current HIV/AIDS Reports. Mar, 2012 | Pubmed ID: 22198819 Association of IL-10-promoter Genetic Variants with the Rate of CD4 T-cell Loss, IL-10 Plasma Levels, and Breadth of Cytotoxic T-cell Lymphocyte Response During Chronic HIV-1 Infection Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Jan, 2012 | Pubmed ID: 22100578 Rilevamento Di Intranasale Consegnate Derivate Da Midollo Osseo Mesenchymal Cellule Stromali Del Cervello Del Mouse Elettivamente: Un Rapporto Cauzionale Stem Cells International. 2011 | Pubmed ID: 22190964 HIV Controllers: a Multifactorial Phenotype of Spontaneous Viral Suppression Clinical Immunology (Orlando, Fla.). Oct, 2011 | Pubmed ID: 21865089 High-functional-avidity Cytotoxic T Lymphocyte Responses to HLA-B-restricted Gag-derived Epitopes Associated with Relative HIV Control Journal of Virology. Sep, 2011 | Pubmed ID: 21752903 Responsiveness of HIV-specific CD4 T Cells to PD-1 Blockade Blood. Jul, 2011 | Pubmed ID: 21652684 HIV-specific CD4 T Cells and Immune Control of Viral Replication Current Opinion in HIV and AIDS. May, 2011 | Pubmed ID: 21502921 Epithelial Adhesion Molecules Can Inhibit HIV-1-specific CD8⺠T-cell Functions Blood. May, 2011 | Pubmed ID: 21403126 Ets-1 Maintains IL-7 Receptor Expression in Peripheral T Cells Journal of Immunology (Baltimore, Md. : 1950). Jan, 2011 | Pubmed ID: 21148801 Expression of PD-L1 and PD-L2 on Human Macrophages is Up-regulated by HIV-1 and Differentially Modulated by IL-10 Journal of Leukocyte Biology. Apr, 2011 | Pubmed ID: 21097698 Transcriptional Analysis of HIV-specific CD8+ T Cells Shows That PD-1 Inhibits T Cell Function by Upregulating BATF Nature Medicine. Oct, 2010 | Pubmed ID: 20890291 Protective And detrimental Roles Of IL-10 In HIV Pathogenesis European Cytokine Network. Sep, 2010 | Pubmed ID: 20732847 Impaired Replication Capacity of Acute/early Viruses in Persons Who Become HIV Controllers Journal of Virology. Aug, 2010 | Pubmed ID: 20504921 Adattamento Virale Alla Pressione Di Selezione Immuni Da HLA Classe I-limitato CTL Risposte Targeting Epitopi in HIV Frameshift Sequenze The Journal of Experimental Medicine. Jan, 2010 | Pubmed ID: 20065065 Inhibitory TCR Coreceptor PD-1 is a Sensitive Indicator of Low-level Replication of SIV and HIV-1 Journal of Immunology (Baltimore, Md. : 1950). Jan, 2010 | Pubmed ID: 19949078 PD-1 and CTLA-4 Inhibitory Cosignaling Pathways in HIV Infection and the Potential for Therapeutic Intervention Journal of Immunology (Baltimore, Md. : 1950). May, 2009 | Pubmed ID: 19414738 IL-10 is Up-regulated in Multiple Cell Types During Viremic HIV Infection and Reversibly Inhibits Virus-specific T Cells Blood. Jul, 2009 | Pubmed ID: 19365081 Immunodominant HIV-1 Cd4+ T Cell Epitopes in Chronic Untreated Clade C HIV-1 Infection PloS One. 2009 | Pubmed ID: 19352428 Adescamento in Vitro Ricapitola in Vivo Dell'HIV-1 Specifica Delle Cellule T Risposte, Rivelando La Rapida Perdita Di Virus Reattive Cellule T CD4 in Infezione Acuta Da HIV-1 PloS One. 2009 | Pubmed ID: 19165342 Programmed Death-1 As a Factor in Immune Exhaustion and Activation in HIV Infection Current Opinion in HIV and AIDS. May, 2008 | Pubmed ID: 19372991 Genetic and Immunologic Heterogeneity Among Persons Who Control HIV Infection in the Absence of Therapy The Journal of Infectious Diseases. Feb, 2008 | Pubmed ID: 18275276 Treatment Interruption to Boost Specific HIV Immunity in Acute Infection Current Opinion in HIV and AIDS. Jan, 2007 | Pubmed ID: 19372861 Increased Sequence Diversity Coverage Improves Detection of HIV-specific T Cell Responses Journal of Immunology (Baltimore, Md. : 1950). Nov, 2007 | Pubmed ID: 17982054 Upregulation Di CTLA-4 Da Parte Delle Cellule T CD4 + Specifiche Per L'HIV Correla Con La Progressione Della Malattia E Definisce Una Reversibile Disfunzione Immunitaria Nature Immunology. Nov, 2007 | Pubmed ID: 17906628 Litici E Latenti Antigeni Del Virus Epstein - Barr E Gammaherpesviruses Umano Associato Al Sarcoma Di Kaposi Herpesvirus Inducono Risposte Delle Cellule T Con Simili Proprietà Funzionali E Fenotipi Di Memoria Journal of Virology. May, 2007 | Pubmed ID: 17329344 Impaired Hepatitis C Virus-specific T Cell Responses and Recurrent Hepatitis C Virus in HIV Coinfection PLoS Medicine. Dec, 2006 | Pubmed ID: 17194190 Infection of CD127+ (interleukin-7 Receptor+) CD4+ Cells and Overexpression of CTLA-4 Are Linked to Loss of Antigen-specific CD4 T Cells During Primary Human Immunodeficiency Virus Type 1 Infection Journal of Virology. Oct, 2006 | Pubmed ID: 17005693 PD-1 Expression on HIV-specific T Cells is Associated with T-cell Exhaustion and Disease Progression Nature. Sep, 2006 | Pubmed ID: 16921384 Espansione Di Cellule Specifiche Per L'HIV CD4 + E CD8 + T Dalle Cellule Dendritiche Transfected Con MRNA Codifica Citoplasma O Lisosoma-targeting Nef Blood. Mar, 2006 | Pubmed ID: 16249391 Selective Escape from CD8+ T-cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution Journal of Virology. Nov, 2005 | Pubmed ID: 16227247 Early Proliferation of CCR5(+) CD38(+++) Antigen-specific CD4(+) Th1 Effector Cells During Primary HIV-1 Infection Blood. Sep, 2005 | Pubmed ID: 15905189 Limited Durability of Viral Control Following Treated Acute HIV Infection PLoS Medicine. Nov, 2004 | Pubmed ID: 15526059 Perdita Di Proliferazione Delle Cellule T CD8 + HIV-1-specifiche Dopo Infezione Acuta Da HIV-1 E Restauro Da Vaccino-indotta Delle Cellule T CD4 + Specifiche Dell'HIV-1 The Journal of Experimental Medicine. Sep, 2004 | Pubmed ID: 15381726 Beyond Help: Direct Effector Functions of Human Immunodeficiency Virus Type 1-specific CD4(+) T Cells Journal of Virology. Aug, 2004 | Pubmed ID: 15280492 Fine Specificity and Cross-clade Reactivity of HIV Type 1 Gag-specific CD4+ T Cells AIDS Research and Human Retroviruses. Mar, 2004 | Pubmed ID: 15117455 Comprehensive Analysis of Human Immunodeficiency Virus Type 1-specific CD4 Responses Reveals Marked Immunodominance of Gag and Nef and the Presence of Broadly Recognized Peptides Journal of Virology. May, 2004 | Pubmed ID: 15078927 The Value of Preserving HIV-specific Immune Responses Journal of HIV Therapy. Feb, 2003 | Pubmed ID: 12840711 In vitro per valutare l'impatto di immunoregolatorio Pathways su HIV-specifica CD4 T effettrici delle cellule di funzione Filippos Porichis*1, Meghan G. Hart*1, Jennifer Zupkosky1, Lucie Barblu1,2, Daniel E. Kaufmann1,2 1The Ragon Institute of MGH, MIT and Harvard, 2Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM) JoVE 50821 Immunology and Infection
In vitro per valutare l'impatto di immunoregolatorio Pathways su HIV-specifica CD4 T effettrici delle cellule di funzione Filippos Porichis*1, Meghan G. Hart*1, Jennifer Zupkosky1, Lucie Barblu1,2, Daniel E. Kaufmann1,2 1The Ragon Institute of MGH, MIT and Harvard, 2Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM) JoVE 50821 Immunology and Infection
