Daniel Khananshvili Department of Physiology and Pharmacology, Sackler Faculty of Medicine Tel Aviv University Biography Publications Institution JoVE Articles Daniel Khananshvili has not added a biography. If you are Daniel Khananshvili and would like to personalize this page please email our Author Liaison for assistance. Publications How a Helix Imposes Palmitoylation of a Membrane Protein: What One Can Learn from NCX The Journal of Biological Chemistry. Jun, 2017 | Pubmed ID: 28646126 Dynamic Distinctions in the Na(+)/Ca(2+) Exchanger Adopting the Inward- and Outward-facing Conformational States The Journal of Biological Chemistry. Jul, 2017 | Pubmed ID: 28572509 Structure-based Dynamic Arrays in Regulatory Domains of Sodium-calcium Exchanger (NCX) Isoforms Scientific Reports. Apr, 2017 | Pubmed ID: 28428550 Purification and Characterization of Human Dehydrodolychil Diphosphate Synthase (DHDDS) Overexpressed in E. coli Protein Expression and Purification. Apr, 2017 | Pubmed ID: 28167250 Structure-Functional Basis of Ion Transport in Sodium-Calcium Exchanger (NCX) Proteins International Journal of Molecular Sciences. Nov, 2016 | Pubmed ID: 27879668 Structure-Based Engineering of Lithium-Transport Capacity in an Archaeal Sodium-Calcium Exchanger Biochemistry. Mar, 2016 | Pubmed ID: 26958982 Kinetic and Equilibrium Properties of Regulatory Ca(2+)-binding Domains in Sodium-calcium Exchangers 2 and 3 Cell Calcium. 04, 2016 | Pubmed ID: 26924806 Structural Features of Ion Transport and Allosteric Regulation in Sodium-Calcium Exchanger (NCX) Proteins Frontiers in Physiology. 2016 | Pubmed ID: 26903880 Asymmetric Preorganization of Inverted Pair Residues in the Sodium-Calcium Exchanger Scientific Reports. Feb, 2016 | Pubmed ID: 26876271 Structure-dynamic Basis of Splicing-dependent Regulation in Tissue-specific Variants of the Sodium-calcium Exchanger FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2016 | Pubmed ID: 26644350 Structure-dynamic Determinants Governing a Mode of Regulatory Response and Propagation of Allosteric Signal in Splice Variants of Na+/Ca2+ Exchange (NCX) Proteins The Biochemical Journal. Feb, 2015 | Pubmed ID: 25387769 Sodium Recognition by the Na+/Ca2+ Exchanger in the Outward-facing Conformation Proceedings of the National Academy of Sciences of the United States of America. Dec, 2014 | Pubmed ID: 25468964 Functional Asymmetry of Bidirectional Ca2+-movements in an Archaeal Sodium-calcium Exchanger (NCX_Mj) Cell Calcium. Oct, 2014 | Pubmed ID: 25218934 Sodium-calcium Exchangers (NCX): Molecular Hallmarks Underlying the Tissue-specific and Systemic Functions Pflugers Archiv : European Journal of Physiology. Jan, 2014 | Pubmed ID: 24281864 The C2B Domain is the Primary Ca2+ Sensor in DOC2B: a Structural and Functional Analysis Journal of Molecular Biology. Nov, 2013 | Pubmed ID: 23994332 Population Shift Underlies Ca2+-induced Regulatory Transitions in the Sodium-calcium Exchanger (NCX) The Journal of Biological Chemistry. Aug, 2013 | Pubmed ID: 23798674 SK4 Ca2+ Activated K+ Channel is a Critical Player in Cardiac Pacemaker Derived from Human Embryonic Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Apr, 2013 | Pubmed ID: 23589888 NCLX: the Mitochondrial Sodium Calcium Exchanger Journal of Molecular and Cellular Cardiology. Jun, 2013 | Pubmed ID: 23538132 The SLC8 Gene Family of Sodium-calcium Exchangers (NCX) - Structure, Function, and Regulation in Health and Disease Molecular Aspects of Medicine. Apr-Jun, 2013 | Pubmed ID: 23506867 Molecular Determinants of Allosteric Regulation in NCX Proteins Advances in Experimental Medicine and Biology. 2013 | Pubmed ID: 23224868 The Mitochondrial Na+/Ca2+ Exchanger Upregulates Glucose Dependent Ca2+ Signalling Linked to Insulin Secretion PloS One. 2012 | Pubmed ID: 23056385 G503 is Obligatory for Coupling of Regulatory Domains in NCX Proteins Biochemistry. Sep, 2012 | Pubmed ID: 22924554 A Common Ca2+-driven Interdomain Module Governs Eukaryotic NCX Regulation PloS One. 2012 | Pubmed ID: 22768191 Dynamic Features of Allosteric Ca2+ Sensor in Tissue-specific NCX Variants Cell Calcium. Jun, 2012 | Pubmed ID: 22571864 Proton-sensing Ca2+ Binding Domains Regulate the Cardiac Na+/Ca2+ Exchanger The Journal of Biological Chemistry. Aug, 2011 | Pubmed ID: 21680748 Essential Role of the CBD1-CBD2 Linker in Slow Dissociation of Ca2+ from the Regulatory Two-domain Tandem of NCX1 The Journal of Biological Chemistry. Sep, 2010 | Pubmed ID: 20587421 NCLX is an Essential Component of Mitochondrial Na+/Ca2+ Exchange Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010 | Pubmed ID: 20018762 Kinetic and Equilibrium Properties of Regulatory Calcium Sensors of NCX1 Protein The Journal of Biological Chemistry. Mar, 2009 | Pubmed ID: 19141619 Direct Loading of the Purified Endogenous Inhibitor into the Cytoplasm of Patched Cardiomyocytes Blocks the Ion Currents and Calcium Transport Through the NCX1 Protein Biochemistry. Jun, 2008 | Pubmed ID: 18507397 Effects of Purified Endogenous Inhibitor of the Na+/Ca2+ Exchanger on Ouabain-induced Arrhythmias in the Atria and Ventricle Strips of Guinea Pig European Journal of Pharmacology. Dec, 2006 | Pubmed ID: 17078946 Single Alpha-domain Constructs of the Na+/Ca2+ Exchanger, NCLX, Oligomerize to Form a Functional Exchanger Biochemistry. Oct, 2006 | Pubmed ID: 17002286 Purified Endogenous Inhibitor of the Na/Ca Exchanger Can Enhance the Cardiomyocytes Contractility and Calcium Transients Biochemical and Biophysical Research Communications. Aug, 2006 | Pubmed ID: 16782052 Advanced Procedures for Separation and Analysis of Low Molecular Weight Inhibitor (NCXIF) of the Cardiac Sodium-calcium Exchanger Biochemical and Biophysical Research Communications. Nov, 2005 | Pubmed ID: 16226722 The Low Molecular Weight Inhibitor of NCX1 Interacts with a Cytosolic Domain That Differs from the Ion-transport Site of the Na/Ca Exchanger Biochemical and Biophysical Research Communications. Nov, 2004 | Pubmed ID: 15504362 Inotropic and Lusitropic Effects Induced by the Inhibitory Factor of the Na/Ca Exchanger Are Not Mediated by the Beta-adrenergic Activation Journal of Cardiovascular Pharmacology. Oct, 2004 | Pubmed ID: 15454855 The Endogenous Inhibitor of NCX1 Does Not Resemble the Properties of Digitalis Compound Biochemical and Biophysical Research Communications. Aug, 2003 | Pubmed ID: 12890488 Sovrapressione e purificazione dell'uomo Ilan Edri*1, Michal Goldenberg*1, Michal Lisnyansky2, Roi Strulovich2, Hadas Newman1,3, Anat Loewenstein1,3, Daniel Khananshvili2, Moshe Giladi2,4, Yoni Haitin2 1Sackler Faculty of Medicine, Tel Aviv University, 2Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, 3Department of Ophthalmology, Tel Aviv Sourasky Medical Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, 4Tel Aviv Sourasky Medical Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University JoVE 56430 Immunology and Infection
Sovrapressione e purificazione dell'uomo Ilan Edri*1, Michal Goldenberg*1, Michal Lisnyansky2, Roi Strulovich2, Hadas Newman1,3, Anat Loewenstein1,3, Daniel Khananshvili2, Moshe Giladi2,4, Yoni Haitin2 1Sackler Faculty of Medicine, Tel Aviv University, 2Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, 3Department of Ophthalmology, Tel Aviv Sourasky Medical Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, 4Tel Aviv Sourasky Medical Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University JoVE 56430 Immunology and Infection