Publications

• Bile Acid Recognition by NAPE-PLD
  ACS Chemical Biology. Oct, 2016  |   Pubmed ID: 27571266
• A Primary Cortical Input to Hippocampus Expresses a Pathway-Specific and Endocannabinoid-Dependent Form of Long-Term Potentiation
  ENeuro. Jul-Aug, 2016  |   Pubmed ID: 27517090
• Free-energy Studies Reveal a Possible Mechanism for Oxidation-dependent Inhibition of MGL
  Scientific Reports. Aug, 2016  |   Pubmed ID: 27499063
• Endogenous N-acyl Taurines Regulate Skin Wound Healing
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2016  |   Pubmed ID: 27412859
• Second-Generation Non-Covalent NAAA Inhibitors Are Protective in a Model of Multiple Sclerosis
  Angewandte Chemie (International Ed. in English). Sep, 2016  |   Pubmed ID: 27404798
• Absolute Nutrient Concentration Measurements in Cell Culture Media: (1)H Q-NMR Spectra and Data to Compare the Efficiency of PH-controlled Protein Precipitation Versus CPMG or Post-processing Filtering Approaches
  Data in Brief. Sep, 2016  |   Pubmed ID: 27331118
• Obesity Development in Neuron-specific Lipoprotein Lipase Deficient Mice is Not Responsive to Increased Dietary Fat Content or Change in Fat Composition
  Metabolism: Clinical and Experimental. Jul, 2016  |   Pubmed ID: 27282869
• Assay of Monoacylglycerol Lipase Activity
  Methods in Molecular Biology (Clifton, N.J.). 2016  |   Pubmed ID: 27245902
• Ion Mobility Mass Spectrometry Enhances Low-abundance Species Detection in Untargeted Lipidomics
  Metabolomics : Official Journal of the Metabolomic Society. 2016  |   Pubmed ID: 26900387
• A Simple and Accurate Protocol for Absolute Polar Metabolite Quantification in Cell Cultures Using Quantitative Nuclear Magnetic Resonance
  Analytical Biochemistry. May, 2016  |   Pubmed ID: 26898303
• Vaccenic Acid Suppresses Intestinal Inflammation by Increasing the Endocannabinoid Anandamide and Non-cannabinoid Signaling Molecules in a Rat Model of the Metabolic Syndrome
  Journal of Lipid Research. Feb, 2016  |   Pubmed ID: 26891736
• Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain
  Journal of Medicinal Chemistry. Mar, 2016  |   Pubmed ID: 26888301
• A Role for the Endocannabinoid 2-arachidonoyl-sn-glycerol for Social and High-fat Food Reward in Male Mice
  Psychopharmacology. May, 2016  |   Pubmed ID: 26873082
• Potent α-amino-β-lactam Carbamic Acid Ester As NAAA Inhibitors. Synthesis and Structure-activity Relationship (SAR) Studies
  European Journal of Medicinal Chemistry. Mar, 2016  |   Pubmed ID: 26866968
• Potent Multitarget FAAH-COX Inhibitors: Design and Structure-activity Relationship Studies
  European Journal of Medicinal Chemistry. Feb, 2016  |   Pubmed ID: 26774927
• Fluorine Nuclear Magnetic Resonance-based Assay in Living Mammalian Cells
  Analytical Biochemistry. Feb, 2016  |   Pubmed ID: 26686030
• Macrophage-derived Lipid Agonists of PPAR-α As Intrinsic Controllers of Inflammation
  Critical Reviews in Biochemistry and Molecular Biology. 2016  |   Pubmed ID: 26585314
• Effects of Fatty Acid Amide Hydrolase (FAAH) Inhibitors on Working Memory in Rats
  Psychopharmacology. May, 2016  |   Pubmed ID: 26558620
• Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION
  The Journal of Biological Chemistry. Jan, 2016  |   Pubmed ID: 26553872
• A Double Whammy: Targeting Both Fatty Acid Amide Hydrolase (FAAH) and Cyclooxygenase (COX) To Treat Pain and Inflammation
  ChemMedChem. Jun, 2016  |   Pubmed ID: 26486424
• Endocannabinoid Modulation of Predator Stress-Induced Long-Term Anxiety in Rats
  Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Apr, 2016  |   Pubmed ID: 26361059
• Monoglyceride Lipase: Structure and Inhibitors
  Chemistry and Physics of Lipids. May, 2016  |   Pubmed ID: 26216043
• Role of the Satiety Factor Oleoylethanolamide in Alcoholism
  Addiction Biology. Jul, 2016  |   Pubmed ID: 26037332
• Benzoxazolone Carboxamides As Potent Acid Ceramidase Inhibitors: Synthesis and Structure-Activity Relationship (SAR) Studies
  Journal of Medicinal Chemistry. Dec, 2015  |   Pubmed ID: 26560855
• Endocannabinoid Signaling Mediates Oxytocin-driven Social Reward
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2015  |   Pubmed ID: 26504214
• Fasting Stimulates 2-AG Biosynthesis in the Small Intestine: Role of Cholinergic Pathways
  American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Oct, 2015  |   Pubmed ID: 26290104
• Deficiency of Lipoprotein Lipase in Neurons Decreases AMPA Receptor Phosphorylation and Leads to Neurobehavioral Abnormalities in Mice
  PloS One. 2015  |   Pubmed ID: 26263173
• Activity-Based Probe for N-Acylethanolamine Acid Amidase
  ACS Chemical Biology. Sep, 2015  |   Pubmed ID: 26102511
• Feeding-induced Oleoylethanolamide Mobilization is Disrupted in the Gut of Diet-induced Obese Rodents
  Biochimica Et Biophysica Acta. Sep, 2015  |   Pubmed ID: 26024927
• Peroxide-Dependent MGL Sulfenylation Regulates 2-AG-Mediated Endocannabinoid Signaling in Brain Neurons
  Chemistry & Biology. May, 2015  |   Pubmed ID: 26000748
• Peripheral FAAH and Soluble Epoxide Hydrolase Inhibitors Are Synergistically Antinociceptive
  Pharmacological Research. Jul, 2015  |   Pubmed ID: 25882247
• A Potent Systemically Active N-Acylethanolamine Acid Amidase Inhibitor That Suppresses Inflammation and Human Macrophage Activation
  ACS Chemical Biology. Aug, 2015  |   Pubmed ID: 25874594
• Multitarget Fatty Acid Amide Hydrolase/cyclooxygenase Blockade Suppresses Intestinal Inflammation and Protects Against Nonsteroidal Anti-inflammatory Drug-dependent Gastrointestinal Damage
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2015  |   Pubmed ID: 25757568
• Effects of Fatty Acid Amide Hydrolase (FAAH) Inhibitors in Non-Human Primate Models of Nicotine Reward and Relapse
  Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Aug, 2015  |   Pubmed ID: 25754762
• Rapid Evaluation of 25 Key Sphingolipids and Phosphosphingolipids in Human Plasma by LC-MS/MS
  Analytical and Bioanalytical Chemistry. Jul, 2015  |   Pubmed ID: 25749796
• Modulation of Sweet Taste Sensitivities by Endogenous Leptin and Endocannabinoids in Mice
  The Journal of Physiology. Jun, 2015  |   Pubmed ID: 25728242
• Structure of Human N-acylphosphatidylethanolamine-hydrolyzing Phospholipase D: Regulation of Fatty Acid Ethanolamide Biosynthesis by Bile Acids
  Structure (London, England : 1993). Mar, 2015  |   Pubmed ID: 25684574
• Methamphetamine Accelerates Cellular Senescence Through Stimulation of De Novo Ceramide Biosynthesis
  PloS One. 2015  |   Pubmed ID: 25671639
• Intestinal Lipid-derived Signals That Sense Dietary Fat
  The Journal of Clinical Investigation. Mar, 2015  |   Pubmed ID: 25642767
• Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase
  Angewandte Chemie (International Ed. in English). Jan, 2015  |   Pubmed ID: 25395373
• O-(triazolyl)methyl Carbamates As a Novel and Potent Class of Fatty Acid Amide Hydrolase (FAAH) Inhibitors
  ChemMedChem. Feb, 2015  |   Pubmed ID: 25338703
• A Lipid Gate for the Peripheral Control of Pain
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2014  |   Pubmed ID: 25392487
• Synthesis, Biological Evaluation, and 3D QSAR Study of 2-methyl-4-oxo-3-oxetanylcarbamic Acid Esters As N-acylethanolamine Acid Amidase (NAAA) Inhibitors
  Journal of Medicinal Chemistry. Dec, 2014  |   Pubmed ID: 25380517
• Structural Determinants of Peripheral O-arylcarbamate FAAH Inhibitors Render Them Dual Substrates for Abcb1 and Abcg2 and Restrict Their Access to the Brain
  Pharmacological Research. Sep, 2014  |   Pubmed ID: 24993496
• A Mighty (ochondrial) Fight?
  Molecular Metabolism. Jul, 2014  |   Pubmed ID: 24944892
• Role of Oleoylethanolamide As a Feeding Regulator in Goldfish
  The Journal of Experimental Biology. Aug, 2014  |   Pubmed ID: 24855680
• 3-Aminoazetidin-2-one Derivatives As N-acylethanolamine Acid Amidase (NAAA) Inhibitors Suitable for Systemic Administration
  ChemMedChem. Jul, 2014  |   Pubmed ID: 24828120
• Cannabinoid Type 1 Receptor Availability in the Amygdala Mediates Threat Processing in Trauma Survivors
  Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Oct, 2014  |   Pubmed ID: 24820537
• Advances in the Discovery of N-acylethanolamine Acid Amidase Inhibitors
  Pharmacological Research. Aug, 2014  |   Pubmed ID: 24798679
• Sample Preparation and Orthogonal Chromatography for Broad Polarity Range Plasma Metabolomics: Application to Human Subjects with Neurodegenerative Dementia
  Analytical Biochemistry. Jun, 2014  |   Pubmed ID: 24708938
• Applying a Multitarget Rational Drug Design Strategy: the First Set of Modulators with Potent and Balanced Activity Toward Dopamine D3 Receptor and Fatty Acid Amide Hydrolase
  Chemical Communications (Cambridge, England). May, 2014  |   Pubmed ID: 24691497
• A Discount on Cannabinoids
  Biological Psychiatry. Mar, 2014  |   Pubmed ID: 24560432
• Peripheral Gating of Pain Signals by Endogenous Lipid Mediators
  Nature Neuroscience. Feb, 2014  |   Pubmed ID: 24473264
• Circadian Control of Fatty Acid Elongation by SIRT1 Protein-mediated Deacetylation of Acetyl-coenzyme A Synthetase 1
  The Journal of Biological Chemistry. Feb, 2014  |   Pubmed ID: 24425865
• Synthesis, Structure-activity, and Structure-stability Relationships of 2-substituted-N-(4-oxo-3-oxetanyl) N-acylethanolamine Acid Amidase (NAAA) Inhibitors
  ChemMedChem. Feb, 2014  |   Pubmed ID: 24403170
• Effects of Acute Stress on Cardiac Endocannabinoids, Lipogenesis, and Inflammation in Rats
  Psychosomatic Medicine. Jan, 2014  |   Pubmed ID: 24367128
• Fluorine NMR-based Screening on Cell Membrane Extracts
  ChemMedChem. Feb, 2014  |   Pubmed ID: 24339446
• A Glycosylated, Labionin-containing Lanthipeptide with Marked Antinociceptive Activity
  ACS Chemical Biology. Feb, 2014  |   Pubmed ID: 24191663
• Lipid-enriched Diet Rescues Lethality and Slows Down Progression in a Murine Model of VCP-associated Disease
  Human Molecular Genetics. Mar, 2014  |   Pubmed ID: 24158850
• More Surprises Lying Ahead. The Endocannabinoids Keep Us Guessing
  Neuropharmacology. Jan, 2014  |   Pubmed ID: 23954677
• Wagging the Tail: Essential Role of Substrate Flexibility in FAAH Catalysis
  Journal of Chemical Theory and Computation. Feb, 2013  |   Pubmed ID: 26588763
• Brown Adipose Tissue Quantification in Human Neonates Using Water-fat Separated MRI
  PloS One. 2013  |   Pubmed ID: 24205024
• Synthesis and Structure-activity Relationship (SAR) of 2-methyl-4-oxo-3-oxetanylcarbamic Acid Esters, a Class of Potent N-acylethanolamine Acid Amidase (NAAA) Inhibitors
  Journal of Medicinal Chemistry. Sep, 2013  |   Pubmed ID: 23991897
• Development of Fragment-based N-FABS NMR Screening Applied to the Membrane Enzyme FAAH
  Chembiochem : a European Journal of Chemical Biology. Sep, 2013  |   Pubmed ID: 23918626
• Synthesis and Structure-activity Relationship Studies of O-biphenyl-3-yl Carbamates As Peripherally Restricted Fatty Acid Amide Hydrolase Inhibitors
  Journal of Medicinal Chemistry. Jul, 2013  |   Pubmed ID: 23822179
• Discovery of a New Class of Highly Potent Inhibitors of Acid Ceramidase: Synthesis and Structure-activity Relationship (SAR)
  Journal of Medicinal Chemistry. May, 2013  |   Pubmed ID: 23614460
• A Fatty Gut Feeling
  Trends in Endocrinology and Metabolism: TEM. Jul, 2013  |   Pubmed ID: 23567058
• Galantamine Potentiates the Neuroprotective Effect of Memantine Against NMDA-induced Excitotoxicity
  Brain and Behavior. Mar, 2013  |   Pubmed ID: 23532860
• Endocannabinoid Signaling in the Gut Mediates Preference for Dietary Unsaturated Fats
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2013  |   Pubmed ID: 23463697
• Pharmacological Characterization of Memoquin, a Multi-target Compound for the Treatment of Alzheimer's Disease
  PloS One. 2013  |   Pubmed ID: 23441223
• Quantum Mechanics/molecular Mechanics Modeling of Fatty Acid Amide Hydrolase Reactivation Distinguishes Substrate from Irreversible Covalent Inhibitors
  Journal of Medicinal Chemistry. Mar, 2013  |   Pubmed ID: 23425199
• Discovery of Highly Potent Acid Ceramidase Inhibitors with in Vitro Tumor Chemosensitizing Activity
  Scientific Reports. 2013  |   Pubmed ID: 23301156
• A Binding Site for Nonsteroidal Anti-inflammatory Drugs in Fatty Acid Amide Hydrolase
  Journal of the American Chemical Society. Jan, 2013  |   Pubmed ID: 23240907
• Antinociceptive Effects of the N-acylethanolamine Acid Amidase Inhibitor ARN077 in Rodent Pain Models
  Pain. Mar, 2013  |   Pubmed ID: 23218523
• β-Lactones Inhibit N-acylethanolamine Acid Amidase by S-Acylation of the Catalytic N-Terminal Cysteine
  ACS Medicinal Chemistry Letters. May, 2012  |   Pubmed ID: 24900487
• Synergistic Effects of Galantamine and Memantine in Attenuating Scopolamine-induced Amnesia in Mice
  Journal of Pharmacological Sciences. 2012  |   Pubmed ID: 23149577
• Identification and Characterization of Carprofen As a Multitarget Fatty Acid Amide Hydrolase/cyclooxygenase Inhibitor
  Journal of Medicinal Chemistry. Oct, 2012  |   Pubmed ID: 23043222
• Combining Galantamine and Memantine in Multitargeted, New Chemical Entities Potentially Useful in Alzheimer's Disease
  Journal of Medicinal Chemistry. Nov, 2012  |   Pubmed ID: 23033965
• Uncoupling of the Endocannabinoid Signalling Complex in a Mouse Model of Fragile X Syndrome
  Nature Communications. 2012  |   Pubmed ID: 23011134
• Peroxisome Proliferator-activated Receptor α Mediates Acute Effects of Palmitoylethanolamide on Sensory Neurons
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2012  |   Pubmed ID: 22972997
• Associations of Fatty Acids in Cerebrospinal Fluid with Peripheral Glucose Concentrations and Energy Metabolism
  PloS One. 2012  |   Pubmed ID: 22911803
• Pretreatment with the Monoacylglycerol Lipase Inhibitor URB602 Protects from the Long-term Consequences of Neonatal Hypoxic-ischemic Brain Injury in Rats
  Pediatric Research. Oct, 2012  |   Pubmed ID: 22821058
• Activation of Type 5 Metabotropic Glutamate Receptors and Diacylglycerol Lipase-α Initiates 2-arachidonoylglycerol Formation and Endocannabinoid-mediated Analgesia
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2012  |   Pubmed ID: 22787031
• Selective Cannabinoid-1 Receptor Blockade Benefits Fatty Acid and Triglyceride Metabolism Significantly in Weight-stable Nonhuman Primates
  American Journal of Physiology. Endocrinology and Metabolism. Sep, 2012  |   Pubmed ID: 22761159
• The Thrifty Lipids: Endocannabinoids and the Neural Control of Energy Conservation
  Trends in Neurosciences. Jul, 2012  |   Pubmed ID: 22622030
• N-(2-oxo-3-oxetanyl)carbamic Acid Esters As N-acylethanolamine Acid Amidase Inhibitors: Synthesis and Structure-activity and Structure-property Relationships
  Journal of Medicinal Chemistry. May, 2012  |   Pubmed ID: 22515328
• Peripheral FAAH Inhibition Causes Profound Antinociception and Protects Against Indomethacin-induced Gastric Lesions
  Pharmacological Research. May, 2012  |   Pubmed ID: 22420940
• 2-arachidonoylglycerol Signaling in Forebrain Regulates Systemic Energy Metabolism
  Cell Metabolism. Mar, 2012  |   Pubmed ID: 22405068
• A Catalytic Mechanism for Cysteine N-terminal Nucleophile Hydrolases, As Revealed by Free Energy Simulations
  PloS One. 2012  |   Pubmed ID: 22389698
• Moving Beyond "good Fat, Bad Fat": the Complex Roles of Dietary Lipids in Cellular Function and Health: Session Abstracts
  Advances in Nutrition (Bethesda, Md.). Jan, 2012  |   Pubmed ID: 22332103
• Decreased Body Weight and Hepatic Steatosis with Altered Fatty Acid Ethanolamide Metabolism in Aged L-Fabp -/- Mice
  Journal of Lipid Research. Apr, 2012  |   Pubmed ID: 22327204
• A Thickening Network of Lipids
  Pain. Jan, 2012  |   Pubmed ID: 22019134
• Endocannabinoid Regulation of Acute and Protracted Nicotine Withdrawal: Effect of FAAH Inhibition
  PloS One. 2011  |   Pubmed ID: 22140525
• A Catalytically Silent FAAH-1 Variant Drives Anandamide Transport in Neurons
  Nature Neuroscience. Nov, 2011  |   Pubmed ID: 22101642
• Elevated Stearoyl-CoA Desaturase in Brains of Patients with Alzheimer's Disease
  PloS One. 2011  |   Pubmed ID: 22046234
• Dietary and Behavioral Interventions Protect Against Age Related Activation of Caspase Cascades in the Canine Brain
  PloS One. 2011  |   Pubmed ID: 21931796
• Covalent Inhibitors of Fatty Acid Amide Hydrolase: a Rationale for the Activity of Piperidine and Piperazine Aryl Ureas
  Journal of Medicinal Chemistry. Oct, 2011  |   Pubmed ID: 21830831
• Biphenyl-3-yl Alkylcarbamates As Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Steric Effects of N-alkyl Chain on Rat Plasma and Liver Stability
  European Journal of Medicinal Chemistry. Sep, 2011  |   Pubmed ID: 21820769
• The ABC Membrane Transporter ABCG2 Prevents Access of FAAH Inhibitor URB937 to the Central Nervous System
  Pharmacological Research. Oct, 2011  |   Pubmed ID: 21767647
• Decoding Functional Metabolomics with Docosahexaenoyl Ethanolamide (DHEA) Identifies Novel Bioactive Signals
  The Journal of Biological Chemistry. Sep, 2011  |   Pubmed ID: 21757729
• Endocannabinoid Signal in the Gut Controls Dietary Fat Intake
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011  |   Pubmed ID: 21730161
• New Lipidomic Approaches in Cystic Fibrosis
  Methods in Molecular Biology (Clifton, N.J.). 2011  |   Pubmed ID: 21547738
• An Amyloid β(42)-dependent Deficit in Anandamide Mobilization is Associated with Cognitive Dysfunction in Alzheimer's Disease
  Neurobiology of Aging. May, 2011  |   Pubmed ID: 21546126
• Towards a Whole-body Systems [multi-organ] Lipidomics in Alzheimer's Disease
  Prostaglandins, Leukotrienes, and Essential Fatty Acids. Nov, 2011  |   Pubmed ID: 21543199
• Diacylglycerol Lipase-alpha and -beta Control Neurite Outgrowth in Neuro-2a Cells Through Distinct Molecular Mechanisms
  Molecular Pharmacology. Jul, 2011  |   Pubmed ID: 21493725
• Sympathetic Activity Controls Fat-induced Oleoylethanolamide Signaling in Small Intestine
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2011  |   Pubmed ID: 21490214
• Plasma Lipidomics Reveals Potential Prognostic Signatures Within a Cohort of Cystic Fibrosis Patients
  Journal of Lipid Research. May, 2011  |   Pubmed ID: 21335323
• Understanding the Role of Carbamate Reactivity in Fatty Acid Amide Hydrolase Inhibition by QM/MM Mechanistic Modelling
  Chemical Communications (Cambridge, England). Mar, 2011  |   Pubmed ID: 21240393
• Proinflammatory Stimuli Control N-acylphosphatidylethanolamine-specific Phospholipase D Expression in Macrophages
  Molecular Pharmacology. Apr, 2011  |   Pubmed ID: 21233218
• Peripheral Antinociceptive Effects of Inhibitors of Monoacylglycerol Lipase in a Rat Model of Inflammatory Pain
  British Journal of Pharmacology. Aug, 2011  |   Pubmed ID: 21198549
• Deficiency of Lipoprotein Lipase in Neurons Modifies the Regulation of Energy Balance and Leads to Obesity
  Cell Metabolism. Jan, 2011  |   Pubmed ID: 21195353
• Central and Peripheral Endocannabinoids and Cognate Acylethanolamides in Humans: Association with Race, Adiposity, and Energy Expenditure
  The Journal of Clinical Endocrinology and Metabolism. Mar, 2011  |   Pubmed ID: 21177788
• Evaluation of the Emotional Phenotype and Serotonergic Neurotransmission of Fatty Acid Amide Hydrolase-deficient Mice
  Psychopharmacology. Mar, 2011  |   Pubmed ID: 21042794
• Blockade of Nicotine Reward and Reinstatement by Activation of Alpha-type Peroxisome Proliferator-activated Receptors
  Biological Psychiatry. Apr, 2011  |   Pubmed ID: 20801430
• PER2 Controls Lipid Metabolism by Direct Regulation of PPARγ
  Cell Metabolism. Nov, 2010  |   Pubmed ID: 21035761
• Ten Years of Nature Reviews Neuroscience: Insights from the Highly Cited
  Nature Reviews. Neuroscience. Oct, 2010  |   Pubmed ID: 20852655
• Anandamide Suppresses Pain Initiation Through a Peripheral Endocannabinoid Mechanism
  Nature Neuroscience. Oct, 2010  |   Pubmed ID: 20852626
• Changes in Cognition and Amyloid-β Processing with Long Term Cholesterol Reduction Using Atorvastatin in Aged Dogs
  Journal of Alzheimer's Disease : JAD. 2010  |   Pubmed ID: 20847439
• Deficient Liver Biosynthesis of Docosahexaenoic Acid Correlates with Cognitive Impairment in Alzheimer's Disease
  PloS One. 2010  |   Pubmed ID: 20838618
• Synthesis and Structure-activity Relationships of N-(2-oxo-3-oxetanyl)amides As N-acylethanolamine-hydrolyzing Acid Amidase Inhibitors
  Journal of Medicinal Chemistry. Aug, 2010  |   Pubmed ID: 20604568
• Genetic Deletion of Fatty Acid Amide Hydrolase Alters Emotional Behavior and Serotonergic Transmission in the Dorsal Raphe, Prefrontal Cortex, and Hippocampus
  Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Sep, 2010  |   Pubmed ID: 20571484
• The Fat-induced Satiety Factor Oleoylethanolamide Suppresses Feeding Through Central Release of Oxytocin
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2010  |   Pubmed ID: 20554860
• Evidence for a Role of Endocannabinoids, Astrocytes and P38 Phosphorylation in the Resolution of Postoperative Pain
  PloS One. 2010  |   Pubmed ID: 20531936
• Pitfalls and Solutions in Assaying Anandamide Transport in Cells
  Journal of Lipid Research. Aug, 2010  |   Pubmed ID: 20447929
• A Role for 2-arachidonoylglycerol and Endocannabinoid Signaling in the Locomotor Response to Novelty Induced by Olfactory Bulbectomy
  Pharmacological Research. May, 2010  |   Pubmed ID: 20044005
• CD36 Gene Deletion Decreases Oleoylethanolamide Levels in Small Intestine of Free-feeding Mice
  Pharmacological Research. Jan, 2010  |   Pubmed ID: 19778614
• Selective N-acylethanolamine-hydrolyzing Acid Amidase Inhibition Reveals a Key Role for Endogenous Palmitoylethanolamide in Inflammation
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2009  |   Pubmed ID: 19926854
• A Novel Lipidomic Strategy Reveals Plasma Phospholipid Signatures Associated with Respiratory Disease Severity in Cystic Fibrosis Patients
  PloS One. Nov, 2009  |   Pubmed ID: 19893743
• Discovery of Potent and Reversible Monoacylglycerol Lipase Inhibitors
  Chemistry & Biology. Oct, 2009  |   Pubmed ID: 19875078
• Lipidomic Analysis of Biological Samples by Liquid Chromatography Coupled to Mass Spectrometry
  Methods in Molecular Biology (Clifton, N.J.). 2009  |   Pubmed ID: 19763477
• A Second Generation of Carbamate-based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in Vivo
  ChemMedChem. Sep, 2009  |   Pubmed ID: 19637155
• The Endocannabinoid System As a Target for Novel Anxiolytic and Antidepressant Drugs
  International Review of Neurobiology. 2009  |   Pubmed ID: 19607961
• Targeted Lipidomics As a Tool to Investigate Endocannabinoid Function
  International Review of Neurobiology. 2009  |   Pubmed ID: 19607960
• Structure-property Relationships of a Class of Carbamate-based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability
  ChemMedChem. Sep, 2009  |   Pubmed ID: 19554599
• Fat-induced Satiety Factor Oleoylethanolamide Enhances Memory Consolidation
  Proceedings of the National Academy of Sciences of the United States of America. May, 2009  |   Pubmed ID: 19416833
• Central Administration of Palmitoylethanolamide Reduces Hyperalgesia in Mice Via Inhibition of NF-kappaB Nuclear Signalling in Dorsal Root Ganglia
  European Journal of Pharmacology. Jun, 2009  |   Pubmed ID: 19386271
• An Endocannabinoid Signal Associated with Desire for Alcohol is Suppressed in Recently Abstinent Alcoholics
  Psychopharmacology. Jul, 2009  |   Pubmed ID: 19343330
• Anandamide Elevation in Cerebrospinal Fluid in Initial Prodromal States of Psychosis
  The British Journal of Psychiatry : the Journal of Mental Science. Apr, 2009  |   Pubmed ID: 19336792
• Lipidomic Analysis of Endocannabinoid Metabolism in Biological Samples
  Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Sep, 2009  |   Pubmed ID: 19171504
• Responses to Stress: from the Periphery to the Brain
  Current Opinion in Pharmacology. Feb, 2009  |   Pubmed ID: 19162545
• Rapid Pain Modulation with Nuclear Receptor Ligands
  Brain Research Reviews. Apr, 2009  |   Pubmed ID: 19162071
• Sleep Deprivation Increases Oleoylethanolamide in Human Cerebrospinal Fluid
  Journal of Neural Transmission (Vienna, Austria : 1996). Mar, 2009  |   Pubmed ID: 19137236
• Synthesis and Characterization of a Peripherally Restricted CB1 Cannabinoid Antagonist, URB447, That Reduces Feeding and Body-weight Gain in Mice
  Bioorganic & Medicinal Chemistry Letters. Feb, 2009  |   Pubmed ID: 19128970
• The Collisional Behavior of ESI-generated Protonated Molecules of Some Carbamate FAAH Inhibitors Isosteres and Its Relationships with Biological Activity
  Journal of Mass Spectrometry : JMS. Apr, 2009  |   Pubmed ID: 19034887
• The Endocannabinoid System As a Target for the Treatment of Cannabis Dependence
  Neuropharmacology. 2009  |   Pubmed ID: 18691603
• Distribution and Function of Monoacylglycerol Lipase in the Gastrointestinal Tract
  American Journal of Physiology. Gastrointestinal and Liver Physiology. Dec, 2008  |   Pubmed ID: 18948437
• The Lipid Messenger OEA Links Dietary Fat Intake to Satiety
  Cell Metabolism. Oct, 2008  |   Pubmed ID: 18840358
• Fatty Acid Amide Hydrolase Inhibition Heightens Anandamide Signaling Without Producing Reinforcing Effects in Primates
  Biological Psychiatry. Dec, 2008  |   Pubmed ID: 18814866
• Inhibition of Anandamide Hydrolysis by Cyclohexyl Carbamic Acid 3'-carbamoyl-3-yl Ester (URB597) Reverses Abuse-related Behavioral and Neurochemical Effects of Nicotine in Rats
  The Journal of Pharmacology and Experimental Therapeutics. Nov, 2008  |   Pubmed ID: 18725543
• The Element of Surprise
  Nature Medicine. Jul, 2008  |   Pubmed ID: 18607371
• An Endocannabinoid Signaling System Modulates Anxiety-like Behavior in Male Syrian Hamsters
  Psychopharmacology. Oct, 2008  |   Pubmed ID: 18545985
• Synthesis and Quantitative Structure-activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-portion of Biphenyl-3-yl Alkylcarbamates
  Journal of Medicinal Chemistry. Jun, 2008  |   Pubmed ID: 18507372
• Increase of Brain Endocannabinoid Anandamide Levels by FAAH Inhibition and Alcohol Abuse Behaviours in the Rat
  Psychopharmacology. Jul, 2008  |   Pubmed ID: 18446329
• Targeted Enhancement of Oleoylethanolamide Production in Proximal Small Intestine Induces Across-meal Satiety in Rats
  American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jul, 2008  |   Pubmed ID: 18434444
• Effects of Palmitoylethanolamide on Signaling Pathways Implicated in the Development of Spinal Cord Injury
  The Journal of Pharmacology and Experimental Therapeutics. Jul, 2008  |   Pubmed ID: 18367664
• Endogenous Cannabinoids in Patients with Schizophrenia and Substance Use Disorder During Quetiapine Therapy
  Journal of Psychopharmacology (Oxford, England). May, 2008  |   Pubmed ID: 18308802
• Identification of Productive Inhibitor Binding Orientation in Fatty Acid Amide Hydrolase (FAAH) by QM/MM Mechanistic Modelling
  Chemical Communications (Cambridge, England). Jan, 2008  |   Pubmed ID: 18092091
• The Effect of Cannabidiol and URB597 on Conditioned Gaping (a Model of Nausea) Elicited by a Lithium-paired Context in the Rat
  Psychopharmacology. Feb, 2008  |   Pubmed ID: 17992520
• Identification of Biosynthetic Precursors for the Endocannabinoid Anandamide in the Rat Brain
  Journal of Lipid Research. Jan, 2008  |   Pubmed ID: 17957091
• The Endogenous Cannabinoid Anandamide Has Effects on Motivation and Anxiety That Are Revealed by Fatty Acid Amide Hydrolase (FAAH) Inhibition
  Neuropharmacology. Jan, 2008  |   Pubmed ID: 17904589
• URB602 Inhibits Monoacylglycerol Lipase and Selectively Blocks 2-arachidonoylglycerol Degradation in Intact Brain Slices
  Chemistry & Biology. Dec, 2007  |   Pubmed ID: 18096504
• Correlation Between Energetics of Collisionally Activated Decompositions, Interaction Energy and Biological Potency of Carbamate FAAH Inhibitors
  Journal of Mass Spectrometry : JMS. Dec, 2007  |   Pubmed ID: 18085570
• Identification of a Bioactive Impurity in a Commercial Sample of 6-methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754)
  Annali Di Chimica. Sep, 2007  |   Pubmed ID: 17970304
• Enhancement of Endocannabinoid Signaling and the Pharmacotherapy of Depression
  Pharmacological Research : the Official Journal of the Italian Pharmacological Society. Nov, 2007  |   Pubmed ID: 17945507
• A Neuroscientist's Guide to Lipidomics
  Nature Reviews. Neuroscience. Oct, 2007  |   Pubmed ID: 17882252
• The Anandamide Transport Inhibitor AM404 Reduces Ethanol Self-administration
  The European Journal of Neuroscience. Jul, 2007  |   Pubmed ID: 17650118
• Hydrolysis of Prostaglandin Glycerol Esters by the Endocannabinoid-hydrolyzing Enzymes, Monoacylglycerol Lipase and Fatty Acid Amide Hydrolase
  Biochemistry. Aug, 2007  |   Pubmed ID: 17649977
• A Key Role for Diacylglycerol Lipase-alpha in Metabotropic Glutamate Receptor-dependent Endocannabinoid Mobilization
  Molecular Pharmacology. Sep, 2007  |   Pubmed ID: 17584991
• Anandamide Levels in Cerebrospinal Fluid of First-episode Schizophrenic Patients: Impact of Cannabis Use
  Schizophrenia Research. Aug, 2007  |   Pubmed ID: 17566707
• Acute Intracerebroventricular Administration of Palmitoylethanolamide, an Endogenous Peroxisome Proliferator-activated Receptor-alpha Agonist, Modulates Carrageenan-induced Paw Edema in Mice
  The Journal of Pharmacology and Experimental Therapeutics. Sep, 2007  |   Pubmed ID: 17565008
• The Antinociceptive Effects of Local Injections of Propofol in Rats Are Mediated in Part by Cannabinoid CB1 and CB2 Receptors
  Anesthesia and Analgesia. Jun, 2007  |   Pubmed ID: 17513659
• Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress
  Biological Psychiatry. Nov, 2007  |   Pubmed ID: 17511970
• Synergistic Antinociception by the Cannabinoid Receptor Agonist Anandamide and the PPAR-alpha Receptor Agonist GW7647
  European Journal of Pharmacology. Jul, 2007  |   Pubmed ID: 17434479
• The Fatty Acid Amide Hydrolase Inhibitor URB597 (cyclohexylcarbamic Acid 3'-carbamoylbiphenyl-3-yl Ester) Reduces Neuropathic Pain After Oral Administration in Mice
  The Journal of Pharmacology and Experimental Therapeutics. Jul, 2007  |   Pubmed ID: 17412883
• Regulation of Brain Anandamide by Acute Administration of Ethanol
  The Biochemical Journal. May, 2007  |   Pubmed ID: 17302558
• The Endogenous Cannabinoid Anandamide Produces Delta-9-tetrahydrocannabinol-like Discriminative and Neurochemical Effects That Are Enhanced by Inhibition of Fatty Acid Amide Hydrolase but Not by Inhibition of Anandamide Transport
  The Journal of Pharmacology and Experimental Therapeutics. Apr, 2007  |   Pubmed ID: 17210800
• Determination of Anandamide and Other Fatty Acyl Ethanolamides in Human Serum by Electrospray Tandem Mass Spectrometry
  Analytical Biochemistry. Feb, 2007  |   Pubmed ID: 17196922
• Food Intake Regulates Oleoylethanolamide Formation and Degradation in the Proximal Small Intestine
  The Journal of Biological Chemistry. Jan, 2007  |   Pubmed ID: 17121838
• Effects of the FAAH Inhibitor, URB597, and Anandamide on Lithium-induced Taste Reactivity Responses: a Measure of Nausea in the Rat
  Psychopharmacology. Feb, 2007  |   Pubmed ID: 17111174
• Conformational Effects in Enzyme Catalysis: Reaction Via a High Energy Conformation in Fatty Acid Amide Hydrolase
  Biophysical Journal. Jan, 2007  |   Pubmed ID: 17098788
• Synergistic Antinociceptive Effects of Anandamide, an Endocannabinoid, and Nonsteroidal Anti-inflammatory Drugs in Peripheral Tissue: a Role for Endogenous Fatty-acid Ethanolamides?
  European Journal of Pharmacology. Nov, 2006  |   Pubmed ID: 17027744
• Rapid Broad-spectrum Analgesia Through Activation of Peroxisome Proliferator-activated Receptor-alpha
  The Journal of Pharmacology and Experimental Therapeutics. Dec, 2006  |   Pubmed ID: 16997973
• The Fatty-acid Amide Hydrolase Inhibitor URB597 Does Not Affect Triacylglycerol Hydrolysis in Rat Tissues
  Pharmacological Research. Nov, 2006  |   Pubmed ID: 16935521
• Synthesis and Structure-activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring
  ChemMedChem. Jan, 2006  |   Pubmed ID: 16892344
• Pharmacological Profile of the Selective FAAH Inhibitor KDS-4103 (URB597)
  CNS Drug Reviews. 2006  |   Pubmed ID: 16834756
• Cold Exposure Stimulates Synthesis of the Bioactive Lipid Oleoylethanolamide in Rat Adipose Tissue
  The Journal of Biological Chemistry. Aug, 2006  |   Pubmed ID: 16785227
• Molecular Composition of the Endocannabinoid System at Glutamatergic Synapses
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2006  |   Pubmed ID: 16723519
• Pharmacological Characterization of Hydrolysis-resistant Analogs of Oleoylethanolamide with Potent Anorexiant Properties
  The Journal of Pharmacology and Experimental Therapeutics. Aug, 2006  |   Pubmed ID: 16702440
• Anxiolytic-like Properties of the Anandamide Transport Inhibitor AM404
  Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Dec, 2006  |   Pubmed ID: 16541083
• Role of the Basolateral Nucleus of the Amygdala in Endocannabinoid-mediated Stress-induced Analgesia
  Neuroscience Letters. Apr, 2006  |   Pubmed ID: 16378681
• Postprandial Increase of Oleoylethanolamide Mobilization in Small Intestine of the Burmese Python (Python Molurus)
  American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. May, 2006  |   Pubmed ID: 16373434
• Actions of the FAAH Inhibitor URB597 in Neuropathic and Inflammatory Chronic Pain Models
  British Journal of Pharmacology. Feb, 2006  |   Pubmed ID: 16331291
• Endocannabinoids at the Spinal Level Regulate, but Do Not Mediate, Nonopioid Stress-induced Analgesia
  Neuropharmacology. Mar, 2006  |   Pubmed ID: 16316669
• Oleylethanolamide Activates Ras-Erk Pathway and Improves Myocardial Function in Doxorubicin-induced Heart Failure
  Endocrinology. Feb, 2006  |   Pubmed ID: 16269455
• Identification and Functional Characterization of Brainstem Cannabinoid CB2 Receptors
  Science (New York, N.Y.). Oct, 2005  |   Pubmed ID: 16224028
• QM/MM Modelling of Oleamide Hydrolysis in Fatty Acid Amide Hydrolase (FAAH) Reveals a New Mechanism of Nucleophile Activation
  Chemical Communications (Cambridge, England). Sep, 2005  |   Pubmed ID: 16136230
• Selective Inhibition of 2-AG Hydrolysis Enhances Endocannabinoid Signaling in Hippocampus
  Nature Neuroscience. Sep, 2005  |   Pubmed ID: 16116451
• Targeted Lipidomics: Signaling Lipids and Drugs of Abuse
  Prostaglandins & Other Lipid Mediators. Sep, 2005  |   Pubmed ID: 16099407
• The Challenge of Brain Lipidomics
  Prostaglandins & Other Lipid Mediators. Sep, 2005  |   Pubmed ID: 16099388
• Stimulation of Endocannabinoid Formation in Brain Slice Cultures Through Activation of Group I Metabotropic Glutamate Receptors
  Molecular Pharmacology. Nov, 2005  |   Pubmed ID: 16051747