Danielle R. Reed Monell Chemical Senses Center Biography Publications Institution JoVE Articles Danielle R. Reed has not added a biography. If you are Danielle R. Reed and would like to personalize this page please email our Author Liaison for assistance. Publications Activation of Airway Epithelial Bitter Taste Receptors by Quinolones Modulates Calcium, Cyclic-AMP, and Nitric Oxide Signaling The Journal of Biological Chemistry. Jun, 2018 | Pubmed ID: 29748385 Burly1 is a Mouse QTL for Lean Body Mass That Maps to a 0.8-Mb Region of Chromosome 2 Mammalian Genome : Official Journal of the International Mammalian Genome Society. Jun, 2018 | Pubmed ID: 29737391 The Role of Quinine-Responsive Taste Receptor Family 2 in Airway Immune Defense and Chronic Rhinosinusitis Frontiers in Immunology. 2018 | Pubmed ID: 29643854 Bitter and Sweet Taste Tests Are Reflective of Disease Status in Chronic Rhinosinusitis The Journal of Allergy and Clinical Immunology. In Practice. May - Jun, 2018 | Pubmed ID: 29054707 Adiposity QTL Adip20 Decomposes into at Least Four Loci when Dissected Using Congenic Strains PloS One. 2017 | Pubmed ID: 29194435 Flavones Modulate Respiratory Epithelial Innate Immunity: Anti-inflammatory Effects and Activation of the T2R14 Receptor The Journal of Biological Chemistry. 05, 2017 | Pubmed ID: 28373278 Genetic Analysis of Impaired Trimethylamine Metabolism Using Whole Exome Sequencing BMC Medical Genetics. Feb, 2017 | Pubmed ID: 28196478 Caffeine Bitterness is Related to Daily Caffeine Intake and Bitter Receptor MRNA Abundance in Human Taste Tissue Perception. Mar-Apr, 2017 | Pubmed ID: 28118781 Association Between the CDHR3 Rs6967330 Risk Allele and Chronic Rhinosinusitis The Journal of Allergy and Clinical Immunology. Jun, 2017 | Pubmed ID: 27923563 Variation in the TAS2R31 Bitter Taste Receptor Gene Relates to Liking for the Nonnutritive Sweetener Acesulfame-K Among Children and Adults Scientific Reports. 12, 2016 | Pubmed ID: 27966661 Is the Association Between Sweet and Bitter Perception Due to Genetic Variation? Chemical Senses. Aug, 2016 | Pubmed ID: 27506221 Sweet Taste Perception is Associated with Body Mass Index at the Phenotypic and Genotypic Level Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies. 10, 2016 | Pubmed ID: 27492574 Genetics of Amino Acid Taste and Appetite Advances in Nutrition (Bethesda, Md.). 07, 2016 | Pubmed ID: 27422518 The Development of Sweet Taste: From Biology to Hedonics Reviews in Endocrine & Metabolic Disorders. May, 2016 | Pubmed ID: 27193110 A Role for Airway Taste Receptor Modulation in the Treatment of Upper Respiratory Infections Expert Review of Respiratory Medicine. Feb, 2016 | Pubmed ID: 26731661 Individual Differences Among Children in Sucrose Detection Thresholds: Relationship With Age, Gender, and Bitter Taste Genotype Nursing Research. Jan-Feb, 2016 | Pubmed ID: 26633761 TAS2R38 Genotype Predicts Surgical Outcome in Nonpolypoid Chronic Rhinosinusitis International Forum of Allergy & Rhinology. Jan, 2016 | Pubmed ID: 26562612 Body Composition QTLs Identified in Intercross Populations Are Reproducible in Consomic Mouse Strains PloS One. 2015 | Pubmed ID: 26551037 Functional Analyses of Bitter Taste Receptors in Domestic Cats (Felis Catus) PloS One. 2015 | Pubmed ID: 26488302 Children's Perceptions About Medicines: Individual Differences and Taste BMC Pediatrics. 2015 | Pubmed ID: 26391354 Recent Advances in Fatty Acid Perception and Genetics Advances in Nutrition (Bethesda, Md.). May, 2015 | Pubmed ID: 25979508 "A Spoonful of Sugar Helps the Medicine Go Down": Bitter Masking by Sucrose Among Children and Adults Chemical Senses. Jan, 2015 | Pubmed ID: 25381313 Genome-wide Meta-analysis Identifies Six Novel Loci Associated with Habitual Coffee Consumption Molecular Psychiatry. May, 2015 | Pubmed ID: 25288136 Age-related Differences in Bitter Taste and Efficacy of Bitter Blockers PloS One. 2014 | Pubmed ID: 25050705 The Bamboo-eating Giant Panda (Ailuropoda Melanoleuca) Has a Sweet Tooth: Behavioral and Molecular Responses to Compounds That Taste Sweet to Humans PloS One. 2014 | Pubmed ID: 24671207 Preferences for Salty and Sweet Tastes Are Elevated and Related to Each Other During Childhood PloS One. 2014 | Pubmed ID: 24637844 The Bitter Taste Receptor T2R38 is an Independent Risk Factor for Chronic Rhinosinusitis Requiring Sinus Surgery International Forum of Allergy & Rhinology. Jan, 2014 | Pubmed ID: 24302675 Genetics of Taste Receptors Current Pharmaceutical Design. 2014 | Pubmed ID: 23886383 Human Bitter Perception Correlates with Bitter Receptor Messenger RNA Expression in Taste Cells The American Journal of Clinical Nutrition. Oct, 2013 | Pubmed ID: 24025627 QTL Analysis of Dietary Obesity in C57BL/6byj X 129P3/J F2 Mice: Diet- and Sex-dependent Effects PloS One. 2013 | Pubmed ID: 23922663 The Bad Taste of Medicines: Overview of Basic Research on Bitter Taste Clinical Therapeutics. Aug, 2013 | Pubmed ID: 23886820 T2R38 Taste Receptor Polymorphisms Underlie Susceptibility to Upper Respiratory Infection The Journal of Clinical Investigation. Nov, 2012 | Pubmed ID: 23041624 Genetic Analysis of Chemosensory Traits in Human Twins Chemical Senses. Sep, 2012 | Pubmed ID: 22977065 Relationship Between Bitter-taste Receptor Genotype and Solid Medication Formulation Usage Among Young Children: a Retrospective Analysis Clinical Therapeutics. Mar, 2012 | Pubmed ID: 22440514 Major Taste Loss in Carnivorous Mammals Proceedings of the National Academy of Sciences of the United States of America. Mar, 2012 | Pubmed ID: 22411809 A Genome-wide Study on the Perception of the Odorants Androstenone and Galaxolide Chemical Senses. Feb, 2012 | Pubmed ID: 22362865 The Gustatory and Olfactory Systems During Infancy: Implications for Development of Feeding Behaviors in the High-risk Neonate Clinics in Perinatology. Dec, 2011 | Pubmed ID: 22107894 Genetics of Sweet Taste Preferences Flavour and Fragrance Journal. Jul, 2011 | Pubmed ID: 21743773 Body Fat Distribution and Organ Weights of 14 Common Strains and a 22-strain Consomic Panel of Rats Physiology & Behavior. Jul, 2011 | Pubmed ID: 21504752 Sweet Taste Receptor Gene Variation and Aspartame Taste in Primates and Other Species Chemical Senses. Jun, 2011 | Pubmed ID: 21414996 Psychophysical Dissection of Genotype Effects on Human Bitter Perception Chemical Senses. Jan, 2011 | Pubmed ID: 20980355 Excretion and Perception of a Characteristic Odor in Urine After Asparagus Ingestion: a Psychophysical and Genetic Study Chemical Senses. Jan, 2011 | Pubmed ID: 20876394 The Perception of Quinine Taste Intensity is Associated with Common Genetic Variants in a Bitter Receptor Cluster on Chromosome 12 Human Molecular Genetics. Nov, 2010 | Pubmed ID: 20675712 Gustation Genetics: Sweet Gustducin! Chemical Senses. Sep, 2010 | Pubmed ID: 20660058 Age Modifies the Genotype-phenotype Relationship for the Bitter Receptor TAS2R38 BMC Genetics. 2010 | Pubmed ID: 20594349 A Marker of Growth Differs Between Adolescents with High Vs. Low Sugar Preference Physiology & Behavior. Mar, 2009 | Pubmed ID: 19150454 Animal Models of Gene-nutrient Interactions Obesity (Silver Spring, Md.). Dec, 2008 | Pubmed ID: 19037208 Involvement of T1R3 in Calcium-magnesium Taste Physiological Genomics. Aug, 2008 | Pubmed ID: 18593862 Birth of a New Breed of Supertaster Chemical Senses. Jul, 2008 | Pubmed ID: 18562444 Calcium Taste Preferences: Genetic Analysis and Genome Screen of C57BL/6J X PWK/PhJ Hybrid Mice Genes, Brain, and Behavior. Aug, 2008 | Pubmed ID: 18363849 QTL for Body Composition on Chromosome 7 Detected Using a Chromosome Substitution Mouse Strain Obesity (Silver Spring, Md.). Feb, 2008 | Pubmed ID: 18239664 Reduced Body Weight is a Common Effect of Gene Knockout in Mice BMC Genetics. Jan, 2008 | Pubmed ID: 18182103 Genetic Loci Affecting Body Weight and Fatness in a C57BL/6J X PWK/PhJ Mouse Intercross Mammalian Genome : Official Journal of the International Mammalian Genome Society. Dec, 2007 | Pubmed ID: 18008102 Twin Study of the Heritability of Recognition Thresholds for Sour and Salty Taste Chemical Senses. Oct, 2007 | Pubmed ID: 17623712 Forty Mouse Strain Survey of Body Composition Physiology & Behavior. Aug, 2007 | Pubmed ID: 17493645 Forty Mouse Strain Survey of Voluntary Calcium Intake, Blood Calcium, and Bone Mineral Content Physiology & Behavior. Aug, 2007 | Pubmed ID: 17493644 Forty Mouse Strain Survey of Water and Sodium Intake Physiology & Behavior. Aug, 2007 | Pubmed ID: 17490693 Quantitative Trait Loci for Individual Adipose Depot Weights in C57BL/6ByJ X 129P3/J F2 Mice Mammalian Genome : Official Journal of the International Mammalian Genome Society. Nov, 2006 | Pubmed ID: 17103053 A Locus on Mouse Chromosome 9 (Adip5) Affects the Relative Weight of the Gonadal but Not Retroperitoneal Adipose Depot Mammalian Genome : Official Journal of the International Mammalian Genome Society. Nov, 2006 | Pubmed ID: 17103052 The Human Sweet Tooth BMC Oral Health. Jun, 2006 | Pubmed ID: 16934118 Diverse Tastes: Genetics of Sweet and Bitter Perception Physiology & Behavior. Jun, 2006 | Pubmed ID: 16782140 Cats Lack a Sweet Taste Receptor The Journal of Nutrition. Jul, 2006 | Pubmed ID: 16772462 Heritability and Genetic Covariation of Sensitivity to PROP, SOA, Quinine HCl, and Caffeine Chemical Senses. Jun, 2006 | Pubmed ID: 16527870 Pseudogenization of a Sweet-receptor Gene Accounts for Cats' Indifference Toward Sugar PLoS Genetics. Jul, 2005 | Pubmed ID: 16103917 No Relationship Between Sequence Variation in Protein Coding Regions of the Tas1r3 Gene and Saccharin Preference in Rats Chemical Senses. Mar, 2005 | Pubmed ID: 15741599 The Molecular Basis of Individual Differences in Phenylthiocarbamide and Propylthiouracil Bitterness Perception Current Biology : CB. Feb, 2005 | Pubmed ID: 15723792 Genetic and Environmental Determinants of Bitter Perception and Sweet Preferences Pediatrics. Feb, 2005 | Pubmed ID: 15687429 Bitter Receptor Gene (TAS2R38), 6-n-propylthiouracil (PROP) Bitterness and Alcohol Intake Alcoholism, Clinical and Experimental Research. Nov, 2004 | Pubmed ID: 15547448 Research Issues in Genetic Testing of Adolescents for Obesity Nutrition Reviews. Aug, 2004 | Pubmed ID: 15478685 Allelic Variation of the Tas1r3 Taste Receptor Gene Selectively Affects Behavioral and Neural Taste Responses to Sweeteners in the F2 Hybrids Between C57BL/6ByJ and 129P3/J Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2004 | Pubmed ID: 14999080 Polymorphisms in the Taste Receptor Gene (Tas1r3) Region Are Associated with Saccharin Preference in 30 Mouse Strains The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2004 | Pubmed ID: 14749438 Loci on Chromosomes 2, 4, 9, and 16 for Body Weight, Body Length, and Adiposity Identified in a Genome Scan of an F2 Intercross Between the 129P3/J and C57BL/6ByJ Mouse Strains Mammalian Genome : Official Journal of the International Mammalian Genome Society. May, 2003 | Pubmed ID: 12856282 Genetics of Sweet Taste Preferences Pure and Applied Chemistry. Chimie Pure Et Appliquee. Jul, 2002 | Pubmed ID: 18270552 Food Intake, Water Intake, and Drinking Spout Side Preference of 28 Mouse Strains Behavior Genetics. Nov, 2002 | Pubmed ID: 12467341 Voluntary Ethanol Consumption by Mice: Genome-wide Analysis of Quantitative Trait Loci and Their Interactions in a C57BL/6ByJ X 129P3/J F2 Intercross Genome Research. Aug, 2002 | Pubmed ID: 12176933 Genetic, Physical, and Comparative Map of the Subtelomeric Region of Mouse Chromosome 4 Mammalian Genome : Official Journal of the International Mammalian Genome Society. Jan, 2002 | Pubmed ID: 11773963 Positional Cloning of the Mouse Saccharin Preference (Sac) Locus Chemical Senses. Sep, 2001 | Pubmed ID: 11555487 The Genetics of Phenylthiocarbamide Perception Annals of Human Biology. Mar-Apr, 2001 | Pubmed ID: 11293722 Nutrient Preference and Diet-induced Adiposity in C57BL/6ByJ and 129P3/J Mice Physiology & Behavior. Mar, 2001 | Pubmed ID: 11282146 High-resolution Genetic Mapping of the Saccharin Preference Locus (Sac) and the Putative Sweet Taste Receptor (T1R1) Gene (Gpr70) to Mouse Distal Chromosome 4 Mammalian Genome : Official Journal of the International Mammalian Genome Society. Jan, 2001 | Pubmed ID: 11178737 Heritable Variation in Food Preferences and Their Contribution to Obesity Behavior Genetics. Jul, 1997 | Pubmed ID: 9519563 Sucrose Consumption in Mice: Major Influence of Two Genetic Loci Affecting Peripheral Sensory Responses Mammalian Genome : Official Journal of the International Mammalian Genome Society. Aug, 1997 | Pubmed ID: 9250857 Taste Exam: A Brief and Validated Test Jennifer E. Douglas1,2, Corrine J. Mansfield2, Charles J. Arayata2, Beverly J. Cowart2, Lauren R. Colquitt2, Ivy W. Maina1,2, Mariel T. Blasetti3, Noam A. Cohen3, Danielle R. Reed2 1Perelman School of Medicine at the University of Pennsylvania, 2Monell Chemical Senses Center, 3Department of Otorhinolaryngology-Head and Neck Surgery, Division of Rhinology, Hospital of the University of Pennsylvania JoVE 56705 Medicine
Taste Exam: A Brief and Validated Test Jennifer E. Douglas1,2, Corrine J. Mansfield2, Charles J. Arayata2, Beverly J. Cowart2, Lauren R. Colquitt2, Ivy W. Maina1,2, Mariel T. Blasetti3, Noam A. Cohen3, Danielle R. Reed2 1Perelman School of Medicine at the University of Pennsylvania, 2Monell Chemical Senses Center, 3Department of Otorhinolaryngology-Head and Neck Surgery, Division of Rhinology, Hospital of the University of Pennsylvania JoVE 56705 Medicine