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Articles by Darren Bryan in JoVE
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Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones
Go Oshima*1,2, Melinda E. Stack*1, Sean C. Wightman1, Darren Bryan1, Elizabeth Poli1, Lai Xue1, Kinga B. Skowron1, Abhineet Uppal1, Sean P. Pitroda2, Xiaona Huang2, Mitchell C. Posner1, Samuel Hellman2, Ralph R. Weichselbaum2, Nikolai N. Khodarev2
1Department of Surgery, The University of Chicago, 2Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, The University of Chicago
The ability of metastatic clones to colonize distant sites depends on their proliferation capacity and/or their ability to survive in the host microenvironment without significant proliferation. Here, we present an animal model that allows quantitative visualization of both types of liver colonization by metastatic clones.
Other articles by Darren Bryan on PubMed
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