David V. Schaffer Department of Chemical & Biomolecular Engineering University of California Berkeley Biography Publications Institution JoVE Articles David V. Schaffer has not added a biography. If you are David V. Schaffer and would like to personalize this page please email our Author Liaison for assistance. Publications β-Catenin Signaling Dynamics Regulate Cell Fate in Differentiating Neural Stem Cells Proceedings of the National Academy of Sciences of the United States of America. 11, 2020 | Pubmed ID: 33139571 The Delivery Challenge: Fulfilling the Promise of Therapeutic Genome Editing Nature Biotechnology. 07, 2020 | Pubmed ID: 32601435 Engineered Illumination Devices for Optogenetic Control of Cellular Signaling Dynamics Cell Reports. 06, 2020 | Pubmed ID: 32521262 Targeted Diversification in the Genome with CRISPR-Guided DNA Polymerase I ACS Synthetic Biology. 07, 2020 | Pubmed ID: 32485105 One-pot Synthesis of Heterodimeric Agonists That Activate the Canonical Wnt Signaling Pathway Chemical Communications (Cambridge, England). Mar, 2020 | Pubmed ID: 32119023 AAVR-Displaying Interfaces: Serotype-Independent Adeno-Associated Virus Capture and Local Delivery Systems Molecular Therapy. Nucleic Acids. Dec, 2019 | Pubmed ID: 31670142 CRISPR-Cas9-Mediated Genome Editing Increases Lifespan and Improves Motor Deficits in a Huntington's Disease Mouse Model Molecular Therapy. Nucleic Acids. Sep, 2019 | Pubmed ID: 31465962 Mastering Their Own Fates Through the Matrix Nature Materials. 08, 2019 | Pubmed ID: 31332317 CRISPR-READI: Efficient Generation of Knockin Mice by CRISPR RNP Electroporation and AAV Donor Infection Cell Reports. 06, 2019 | Pubmed ID: 31242412 Engineering Biomaterials to Control the Neural Differentiation of Stem Cells Brain Research Bulletin. 08, 2019 | Pubmed ID: 31103526 Engineering the AAV Capsid to Evade Immune Responses Current Opinion in Biotechnology. 12, 2019 | Pubmed ID: 30807882 Cheaper and Less Variable Expansion Nature Biomedical Engineering. 03, 2018 | Pubmed ID: 31015716 Understanding How Wnt Influences Destruction Complex Activity and β-Catenin Dynamics IScience. Aug, 2018 | Pubmed ID: 30240607 Corrigendum to "Engineered Viral Vectors for Functional Interrogation, Deconvolution, and Manipulation of Neural Circuits" [Curr. Opin. Neurobiol. 50 (2018) 163-170] Current Opinion in Neurobiology. 12, 2018 | Pubmed ID: 30196036 Spatiomechanical Modulation of EphB4-Ephrin-B2 Signaling in Neural Stem Cell Differentiation Biophysical Journal. 09, 2018 | Pubmed ID: 30075851 CRISPR-guided DNA Polymerases Enable Diversification of All Nucleotides in a Tunable Window Nature. 08, 2018 | Pubmed ID: 30069054 Proliferation Versus Differentiation: Redefining Retinoic Acid's Role Stem Cell Reports. 06, 2018 | Pubmed ID: 29874625 HPSC-Derived Striatal Cells Generated Using a Scalable 3D Hydrogel Promote Recovery in a Huntington Disease Mouse Model Stem Cell Reports. 05, 2018 | Pubmed ID: 29628395 Engineered Viral Vectors for Functional Interrogation, Deconvolution, and Manipulation of Neural Circuits Current Opinion in Neurobiology. 06, 2018 | Pubmed ID: 29614429 Screening for Neutralizing Antibodies Against Natural and Engineered AAV Capsids in Nonhuman Primate Retinas Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29188518 In Vivo Selection of a Computationally Designed SCHEMA AAV Library Yields a Novel Variant for Infection of Adult Neural Stem Cells in the SVZ Molecular Therapy : the Journal of the American Society of Gene Therapy. 01, 2018 | Pubmed ID: 28988711 Combining Engineered Nucleases with Adeno-associated Viral Vectors for Therapeutic Gene Editing Advances in Experimental Medicine and Biology. 2017 | Pubmed ID: 29130152 Efficient Generation of HPSC-derived Midbrain Dopaminergic Neurons in a Fully Defined, Scalable, 3D Biomaterial Platform Scientific Reports. 01, 2017 | Pubmed ID: 28091566 Wnt Regulates Proliferation and Neurogenic Potential of Müller Glial Cells Via a Lin28/let-7 MiRNA-Dependent Pathway in Adult Mammalian Retinas Cell Reports. 09, 2016 | Pubmed ID: 27681429 Enhanced Survival and Engraftment of Transplanted Stem Cells Using Growth Factor Sequestering Hydrogels Biomaterials. Apr, 2015 | Pubmed ID: 25682155 The Expression Pattern of Systemically Injected AAV9 in the Developing Mouse Retina is Determined by Age Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2015 | Pubmed ID: 25224467 Advances in AAV Vector Development for Gene Therapy in the Retina Advances in Experimental Medicine and Biology. 2014 | Pubmed ID: 24664759 Biomaterial Microenvironments to Support the Generation of New Neurons in the Adult Brain Stem Cells (Dayton, Ohio). May, 2014 | Pubmed ID: 24449485 The Effect of Multivalent Sonic Hedgehog on Differentiation of Human Embryonic Stem Cells into Dopaminergic and GABAergic Neurons Biomaterials. Jan, 2014 | Pubmed ID: 24172856 Spatial Organization of Cell-adhesive Ligands for Advanced Cell Culture Biotechnology Journal. Dec, 2013 | Pubmed ID: 24318636 Multivalent Ligands Control Stem Cell Behaviour in Vitro and in Vivo Nature Nanotechnology. Nov, 2013 | Pubmed ID: 24141540 Biophysical Regulation of Stem Cell Behavior Within the Niche Stem Cell Research & Therapy. Dec, 2012 | Pubmed ID: 23241436 X-space MPI: Magnetic Nanoparticles for Safe Medical Imaging Advanced Materials (Deerfield Beach, Fla.). Jul, 2012 | Pubmed ID: 22988557 Astrocytes Regulate Adult Hippocampal Neurogenesis Through Ephrin-B Signaling Nature Neuroscience. Oct, 2012 | Pubmed ID: 22983209 Computational Models of HIV-1 Resistance to Gene Therapy Elucidate Therapy Design Principles PLoS Computational Biology. Aug, 2010 | Pubmed ID: 20711350 Umwandlung Von Wachstumsfaktor-Beta Und Kerbe Signalisierung Vermitteln Stammzell-Differenzierung in Glatten Muskelzellen Stem Cells (Dayton, Ohio). Apr, 2010 | Pubmed ID: 20146266 Characterization of Integrin Engagement During Defined Human Embryonic Stem Cell Culture FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2010 | Pubmed ID: 19933311 Relative Roles of TGF-beta1 and Wnt in the Systemic Regulation and Aging of Satellite Cell Responses Aging Cell. Dec, 2009 | Pubmed ID: 19732043 Molecular Evolution of Adeno-associated Virus for Enhanced Glial Gene Delivery Molecular Therapy : the Journal of the American Society of Gene Therapy. Dec, 2009 | Pubmed ID: 19672246 The Influence of Hydrogel Modulus on the Proliferation and Differentiation of Encapsulated Neural Stem Cells Biomaterials. Sep, 2009 | Pubmed ID: 19539367 Computational Models of the Notch Network Elucidate Mechanisms of Context-dependent Signaling PLoS Computational Biology. May, 2009 | Pubmed ID: 19468305 Control of Stochastic Gene Expression by Host Factors at the HIV Promoter PLoS Pathogens. Jan, 2009 | Pubmed ID: 19132086 Targeted Transgene Expression in Muller Glia of Normal and Diseased Retinas Using Lentiviral Vectors Investigative Ophthalmology & Visual Science. Apr, 2007 | Pubmed ID: 17389520 High-throughput, Library-based Selection of a Murine Leukemia Virus Variant to Infect Nondividing Cells Journal of Virology. Sep, 2006 | Pubmed ID: 16940510 Kinetic Analysis and Modeling of Firefly Luciferase As a Quantitative Reporter Gene in Live Mammalian Cells Biotechnology and Bioengineering. Jun, 2004 | Pubmed ID: 15162459 Theoretical Design of a Gene Therapy to Prevent AIDS but Not Human Immunodeficiency Virus Type 1 Infection Journal of Virology. Sep, 2003 | Pubmed ID: 12941913 Genetic Approaches to Tissue Repair Annals of the New York Academy of Sciences. Jun, 2002 | Pubmed ID: 12081868 Einfache, erschwingliche und modulare Musterung von Zellen mit DNA Katelyn A. Cabral1, David M. Patterson2, Olivia J. Scheideler1, Russell Cole3, Adam R. Abate4,5,6, David V. Schaffer7,8, Lydia L. Sohn9, Zev J. Gartner2,6,10 1Graduate Program in Bioengineering, University of California San Francisco and University of California Berkeley, 2Department of Pharmaceutical Chemistry, University of California San Francisco, 3Scribe Biosciences, 4Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, 5California Institute for Quantitative Biosciences, University of California San Francisco, 6Chan Zuckerberg Biohub, University of California San Francisco, 7Department of Chemical & Biomolecular Engineering, University of California Berkeley, 8Helen Wills Neuroscience Institute, University of California Berkeley, 9Department of Mechanical Engineering, University of California Berkeley, 10Center for Cellular Construction, University of California San Francisco JoVE 61937 Bioengineering
Einfache, erschwingliche und modulare Musterung von Zellen mit DNA Katelyn A. Cabral1, David M. Patterson2, Olivia J. Scheideler1, Russell Cole3, Adam R. Abate4,5,6, David V. Schaffer7,8, Lydia L. Sohn9, Zev J. Gartner2,6,10 1Graduate Program in Bioengineering, University of California San Francisco and University of California Berkeley, 2Department of Pharmaceutical Chemistry, University of California San Francisco, 3Scribe Biosciences, 4Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, 5California Institute for Quantitative Biosciences, University of California San Francisco, 6Chan Zuckerberg Biohub, University of California San Francisco, 7Department of Chemical & Biomolecular Engineering, University of California Berkeley, 8Helen Wills Neuroscience Institute, University of California Berkeley, 9Department of Mechanical Engineering, University of California Berkeley, 10Center for Cellular Construction, University of California San Francisco JoVE 61937 Bioengineering
