David A. Copland

Publications

• Unravelling the Therapeutic Potential of IL-33 for Atrophic AMD
  Eye (London, England). Sep, 2021  |   Pubmed ID: 34531552
• Quantitative Assessment of Experimental Ocular Inflammatory Disease
  Frontiers in Immunology. 2021  |   Pubmed ID: 34220797
• Engineering Adeno-associated Viral Vectors to Evade Innate Immune and Inflammatory Responses
  Science Translational Medicine. 02, 2021  |   Pubmed ID: 33568518
• Cellular Senescence in the Aging Retina and Developments of Senotherapies for Age-related Macular Degeneration
  Journal of Neuroinflammation. Jan, 2021  |   Pubmed ID: 33482879
• Treatment with Interleukin-33 is Non-toxic and Protects Retinal Pigment Epithelium in an Ageing Model of Outer Retinal Degeneration
  Journal of Cellular and Molecular Medicine. 11, 2020  |   Pubmed ID: 33079455
• Treatment of Diabetic Retinopathy Through Neuropeptide Y-mediated Enhancement of Neurovascular Microenvironment
  Journal of Cellular and Molecular Medicine. 04, 2020  |   Pubmed ID: 32141716
• Intravenous Indocyanine Green Dye is Insufficient for Robust Immune Cell Labelling in the Human Retina
  PloS One. 2020  |   Pubmed ID: 32053618
• Gene Therapy for Glaucoma by Ciliary Body Aquaporin 1 Disruption Using CRISPR-Cas9
  Molecular Therapy : the Journal of the American Society of Gene Therapy. 03, 2020  |   Pubmed ID: 31981492
• Single Eye MRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation
  Frontiers in Immunology. 2019  |   Pubmed ID: 31993055
• Modelling Macular Edema: The Effect of IL-6 and IL-6R Blockade on Human Blood-Retinal Barrier Integrity In Vitro
  Translational Vision Science & Technology. Sep, 2019  |   Pubmed ID: 31667008
• Corrigendum to "Restoring Retinal Neurovascular Health Via Substance P" [Exp. Cell Res. (2019)]
  Experimental Cell Research. Sep, 2019  |   Pubmed ID: 31284947
• Restoring Retinal Neurovascular Health Via Substance P
  Experimental Cell Research. 07, 2019  |   Pubmed ID: 30995434
• Müller Cells Stabilize Microvasculature Through Hypoxic Preconditioning
  Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2019  |   Pubmed ID: 30921506
• The Bromodomain and Extra-Terminal Protein Inhibitor OTX015 Suppresses T Helper Cell Proliferation and Differentiation
  Current Molecular Medicine. 2018  |   Pubmed ID: 30683020
• A Perspective of AMD Through the Eyes of Immunology
  Investigative Ophthalmology & Visual Science. 03, 2018  |   Pubmed ID: 30025105
• Re-programming Immunosurveillance in Persistent Non-infectious Ocular Inflammation
  Progress in Retinal and Eye Research. 07, 2018  |   Pubmed ID: 29530739
• Soluble CD200 Correlates With Interleukin-6 Levels in Sera of COPD Patients: Potential Implication of the CD200/CD200R Axis in the Disease Course
  Lung. 02, 2017  |   Pubmed ID: 27864635
• Interleukin-33 Regulates Tissue Remodelling and Inhibits Angiogenesis in the Eye
  The Journal of Pathology. Jan, 2017  |   Pubmed ID: 27701734
• An Anti-TNF-α Antibody Mimetic to Treat Ocular Inflammation
  Scientific Reports. 11, 2016  |   Pubmed ID: 27874029
• Pleiotropic Action of CpG-ODN on Endothelium and Macrophages Attenuates Angiogenesis Through Distinct Pathways
  Scientific Reports. 08, 2016  |   Pubmed ID: 27558877
• Impairing Autophagy in Retinal Pigment Epithelium Leads to Inflammasome Activation and Enhanced Macrophage-mediated Angiogenesis
  Scientific Reports. Feb, 2016  |   Pubmed ID: 26847702
• Multimodal Analysis of Ocular Inflammation Using the Endotoxin-induced Uveitis Mouse Model
  Disease Models & Mechanisms. Apr, 2016  |   Pubmed ID: 26794131
• A Simple Method for in Vivo Labelling of Infiltrating Leukocytes in the Mouse Retina Using Indocyanine Green Dye
  Disease Models & Mechanisms. Nov, 2015  |   Pubmed ID: 26398933
• Role of Interleukin 33/ST2 Axis in the Immune-mediated Pathogenesis of Age-related Macular Degeneration
  Lancet (London, England). Feb, 2015  |   Pubmed ID: 26312920
• A Novel Pathogenic RBP-3 Peptide Reveals Epitope Spreading in Persistent Experimental Autoimmune Uveoretinitis
  Immunology. Oct, 2015  |   Pubmed ID: 26152845
• IL-4 Regulates Specific Arg-1(+) Macrophage SFlt-1-mediated Inhibition of Angiogenesis
  The American Journal of Pathology. Aug, 2015  |   Pubmed ID: 26079814
• Homeostatic Regulation of T Cell Trafficking by a B Cell-derived Peptide is Impaired in Autoimmune and Chronic Inflammatory Disease
  Nature Medicine. May, 2015  |   Pubmed ID: 25894827
• Glucocorticoid-resistant Th17 Cells Are Selectively Attenuated by Cyclosporine A
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2015  |   Pubmed ID: 25775512
• TNFα Regulates SIRT1 Cleavage During Ocular Autoimmune Disease
  The American Journal of Pathology. May, 2015  |   Pubmed ID: 25770475
• Activated Adult Microglia Influence Retinal Progenitor Cell Proliferation and Differentiation Toward Recoverin-expressing Neuron-like Cells in a Co-culture Model
  Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. Jul, 2015  |   Pubmed ID: 25680876
• Local Targeting of the CD200-CD200R Axis Does Not Promote Corneal Graft Survival
  Experimental Eye Research. Jan, 2015  |   Pubmed ID: 25450061
• Tissue-Resident Exhausted Effector Memory CD8+ T Cells Accumulate in the Retina During Chronic Experimental Autoimmune Uveoretinitis
  Journal of Immunology (Baltimore, Md. : 1950). Apr, 2014  |   Pubmed ID: 24740509
• CD200R Signaling Inhibits Pro-angiogenic Gene Expression by Macrophages and Suppresses Choroidal Neovascularization
  Scientific Reports. 2013  |   Pubmed ID: 24170042
• Myeloid Cells Expressing VEGF and Arginase-1 Following Uptake of Damaged Retinal Pigment Epithelium Suggests Potential Mechanism That Drives the Onset of Choroidal Angiogenesis in Mice
  PloS One. 2013  |   Pubmed ID: 23977372
• Environmental Conditioning in the Control of Macrophage Thrombospondin-1 Production
  Scientific Reports. 2012  |   Pubmed ID: 22803005
• Therapeutic Dosing of Fingolimod (FTY720) Prevents Cell Infiltration, Rapidly Suppresses Ocular Inflammation, and Maintains the Blood-ocular Barrier
  The American Journal of Pathology. Feb, 2012  |   Pubmed ID: 22119714
• TNFR1 Signalling is a Critical Checkpoint for Developing Macrophages That Control of T-cell Proliferation
  Immunology. Nov, 2010  |   Pubmed ID: 20518824
• TNFR1-dependent Regulation of Myeloid Cell Function in Experimental Autoimmune Uveoretinitis
  Journal of Immunology (Baltimore, Md. : 1950). Aug, 2009  |   Pubmed ID: 19635911
• Analysis of Retinal Cellular Infiltrate in Experimental Autoimmune Uveoretinitis Reveals Multiple Regulatory Cell Populations
  Journal of Autoimmunity. Dec, 2008  |   Pubmed ID: 18838247
• The Dynamics of Leukocyte Infiltration in Experimental Autoimmune Uveoretinitis
  Progress in Retinal and Eye Research. Sep, 2008  |   Pubmed ID: 18723108
• The B Subunit of Escherichia Coli Heat-labile Enterotoxin Inhibits Th1 but Not Th17 Cell Responses in Established Experimental Autoimmune Uveoretinitis
  Investigative Ophthalmology & Visual Science. Sep, 2008  |   Pubmed ID: 18469197
• Monoclonal Antibody-mediated CD200 Receptor Signaling Suppresses Macrophage Activation and Tissue Damage in Experimental Autoimmune Uveoretinitis
  The American Journal of Pathology. Aug, 2007  |   Pubmed ID: 17600119
• Mapping Immune Responses to MRBP-3 1-16 Peptide with Altered Peptide Ligands
  Investigative Ophthalmology & Visual Science. May, 2006  |   Pubmed ID: 16639012