David J. Sherratt Microbiology Unit, Department of Biochemistry University of Oxford Biography Publications Institution JoVE Articles David J. Sherratt has not added a biography. If you are David J. Sherratt and would like to personalize this page please email our Author Liaison for assistance. Publications Toxin Kid Uncouples DNA Replication and Cell Division to Enforce Retention of Plasmid R1 in Escherichia Coli Cells Proceedings of the National Academy of Sciences of the United States of America. Feb, 2014 | Pubmed ID: 24449860 RecA Bundles Mediate Homology Pairing Between Distant Sisters During DNA Break Repair Nature. Feb, 2014 | Pubmed ID: 24362571 High-copy Bacterial Plasmids Diffuse in the Nucleoid-free Space, Replicate Stochastically and Are Randomly Partitioned at Cell Division Nucleic Acids Research. Jan, 2014 | Pubmed ID: 24137005 Replication-fork Dynamics Cold Spring Harbor Perspectives in Biology. Jan, 2014 | Pubmed ID: 23881939 FtsK-dependent XerCD-dif Recombination Unlinks Replication Catenanes in a Stepwise Manner Proceedings of the National Academy of Sciences of the United States of America. Dec, 2013 | Pubmed ID: 24218579 Conformational Transitions During FtsK Translocase Activation of Individual XerCD-dif Recombination Complexes Proceedings of the National Academy of Sciences of the United States of America. Oct, 2013 | Pubmed ID: 24101525 Single-molecule DNA Repair in Live Bacteria Proceedings of the National Academy of Sciences of the United States of America. May, 2013 | Pubmed ID: 23630273 Breaking Symmetry in SMCs Nature Structural & Molecular Biology. Mar, 2013 | Pubmed ID: 23463306 Hydroxy-terminated Conjugated Polymer Nanoparticles Have Near-unity Bright Fraction and Reveal Cholesterol-dependence of IGF1R Nanodomains ACS Nano. Feb, 2013 | Pubmed ID: 23330847 Capturing Reaction Paths and Intermediates in Cre-loxP Recombination Using Single-molecule Fluorescence Proceedings of the National Academy of Sciences of the United States of America. Dec, 2012 | Pubmed ID: 23184986 In Vivo Architecture and Action of Bacterial Structural Maintenance of Chromosome Proteins Science (New York, N.Y.). Oct, 2012 | Pubmed ID: 23112333 Chromosome Replication and Segregation in Bacteria Annual Review of Genetics. 2012 | Pubmed ID: 22934648 Robustness and Accuracy of Cell Division in Escherichia Coli in Diverse Cell Shapes Proceedings of the National Academy of Sciences of the United States of America. May, 2012 | Pubmed ID: 22509007 Single-molecule Imaging of DNA Curtains Reveals Mechanisms of KOPS Sequence Targeting by the DNA Translocase FtsK Proceedings of the National Academy of Sciences of the United States of America. Apr, 2012 | Pubmed ID: 22493241 Small Plasmids Harboring QnrB19: a Model for Plasmid Evolution Mediated by Site-specific Recombination at OriT and Xer Sites Antimicrobial Agents and Chemotherapy. Apr, 2012 | Pubmed ID: 22290975 Replication and Segregation of an Escherichia Coli Chromosome with Two Replication Origins Proceedings of the National Academy of Sciences of the United States of America. Jun, 2011 | Pubmed ID: 21670292 Activation of XerCD-dif Recombination by the FtsK DNA Translocase Nucleic Acids Research. Jul, 2011 | Pubmed ID: 21371996 Sequence-specific Assembly of FtsK Hexamers Establishes Directional Translocation on DNA Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010 | Pubmed ID: 21048089 Independent Segregation of the Two Arms of the Escherichia Coli Ori Region Requires Neither RNA Synthesis nor MreB Dynamics Journal of Bacteriology. Dec, 2010 | Pubmed ID: 20889756 Stoichiometry and Architecture of Active DNA Replication Machinery in Escherichia Coli Science (New York, N.Y.). Apr, 2010 | Pubmed ID: 20413500 A Streptavidin Variant with Slower Biotin Dissociation and Increased Mechanostability Nature Methods. May, 2010 | Pubmed ID: 20383133 Separating Speed and Ability to Displace Roadblocks During DNA Translocation by FtsK The EMBO Journal. Apr, 2010 | Pubmed ID: 20379135 The Escherichia Coli DNA Translocase FtsK Biochemical Society Transactions. Apr, 2010 | Pubmed ID: 20298190 Fpr, a Deficient Xer Recombination Site from a Salmonella Plasmid, Fails to Confer Stability by Dimer Resolution: Comparative Studies with the PJHCMW1 Mwr Site Journal of Bacteriology. Feb, 2010 | Pubmed ID: 19966005 FtsK Translocation on DNA Stops at XerCD-dif Nucleic Acids Research. Jan, 2010 | Pubmed ID: 19854947 Mwr Xer Site-specific Recombination is Hypersensitive to DNA Supercoiling Nucleic Acids Research. Jun, 2009 | Pubmed ID: 19359357 KOPS-guided DNA Translocation by FtsK Safeguards Escherichia Coli Chromosome Segregation Molecular Microbiology. Feb, 2009 | Pubmed ID: 19170870 Modulation of Escherichia Coli Sister Chromosome Cohesion by Topoisomerase IV Genes & Development. Sep, 2008 | Pubmed ID: 18765793 Molecular Mechanism of Sequence-directed DNA Loading and Translocation by FtsK Molecular Cell. Aug, 2008 | Pubmed ID: 18722176 Visualizing Genetic Loci and Molecular Machines in Living Bacteria Biochemical Society Transactions. Aug, 2008 | Pubmed ID: 18631152 Independent Positioning and Action of Escherichia Coli Replisomes in Live Cells Cell. Apr, 2008 | Pubmed ID: 18394992 Unlinking Chromosome Catenanes in Vivo by Site-specific Recombination The EMBO Journal. Oct, 2007 | Pubmed ID: 17805344 Sublethal Concentrations of the Aminoglycoside Amikacin Interfere with Cell Division Without Affecting Chromosome Dynamics Antimicrobial Agents and Chemotherapy. Jan, 2007 | Pubmed ID: 17043119 The FtsK Gamma Domain Directs Oriented DNA Translocation by Interacting with KOPS Nature Structural & Molecular Biology. Nov, 2006 | Pubmed ID: 17057717 Replication Fork Blockage by Transcription Factor-DNA Complexes in Escherichia Coli Nucleic Acids Research. 2006 | Pubmed ID: 17000639 Double-stranded DNA Translocation: Structure and Mechanism of Hexameric FtsK Molecular Cell. Aug, 2006 | Pubmed ID: 16916635 Regular Cellular Distribution of Plasmids by Oscillating and Filament-forming ParA ATPase of Plasmid PB171 Molecular Microbiology. Sep, 2006 | Pubmed ID: 16899080 The Two Escherichia Coli Chromosome Arms Locate to Separate Cell Halves Genes & Development. Jul, 2006 | Pubmed ID: 16818605 Tracking of Controlled Escherichia Coli Replication Fork Stalling and Restart at Repressor-bound DNA in Vivo The EMBO Journal. Jun, 2006 | Pubmed ID: 16724111 Differences in Resolution of Mwr-containing Plasmid Dimers Mediated by the Klebsiella Pneumoniae and Escherichia Coli XerC Recombinases: Potential Implications in Dissemination of Antibiotic Resistance Genes Journal of Bacteriology. Apr, 2006 | Pubmed ID: 16585742 Dissection of a Functional Interaction Between the DNA Translocase, FtsK, and the XerD Recombinase Molecular Microbiology. Mar, 2006 | Pubmed ID: 16553881 Dancing Around the Divisome: Asymmetric Chromosome Segregation in Escherichia Coli Genes & Development. Oct, 2005 | Pubmed ID: 16204186 Partition-associated Incompatibility Caused by Random Assortment of Pure Plasmid Clusters Molecular Microbiology. Jun, 2005 | Pubmed ID: 15916596 Engineering a 2D Protein-DNA Crystal Angewandte Chemie (International Ed. in English). May, 2005 | Pubmed ID: 15828044 Recombination and Chromosome Segregation Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Jan, 2004 | Pubmed ID: 15065657 Asymmetric Activation of Xer Site-specific Recombination by FtsK EMBO Reports. Apr, 2004 | Pubmed ID: 15031713 Decatenation of DNA Circles by FtsK-dependent Xer Site-specific Recombination The EMBO Journal. Dec, 2003 | Pubmed ID: 14633998 The Aminoglycoside 6'-N-acetyltransferase Type Ib Encoded by Tn1331 is Evenly Distributed Within the Cell's Cytoplasm Antimicrobial Agents and Chemotherapy. Sep, 2003 | Pubmed ID: 12936992 Bacterial Chromosome Dynamics Science (New York, N.Y.). Aug, 2003 | Pubmed ID: 12907786 Spatial and Temporal Organization of Replicating Escherichia Coli Chromosomes Molecular Microbiology. Aug, 2003 | Pubmed ID: 12864855 Species Specificity in the Activation of Xer Recombination at Dif by FtsK Molecular Microbiology. Jul, 2003 | Pubmed ID: 12823825 Functional Analysis of the C-terminal Domains of the Site-specific Recombinases XerC and XerD Journal of Molecular Biology. Jun, 2003 | Pubmed ID: 12818199 Complete Nucleotide Sequence of Klebsiella Pneumoniae Multiresistance Plasmid PJHCMW1 Antimicrobial Agents and Chemotherapy. Nov, 2002 | Pubmed ID: 12384346 Accessory Factors Determine the Order of Strand Exchange in Xer Recombination at Psi The EMBO Journal. Jul, 2002 | Pubmed ID: 12110600 Interactions of Protein Complexes on Supercoiled DNA: the Mechanism of Selective Synapsis by Tn3 Resolvase Journal of Molecular Biology. May, 2002 | Pubmed ID: 12051914 Osmoregulation of Dimer Resolution at the Plasmid PJHCMW1 Mwr Locus by Escherichia Coli XerCD Recombination Journal of Bacteriology. Mar, 2002 | Pubmed ID: 11872712 Визуализация взаимодействий белок-ДНК в живых бактериальных клеток с использованием отслеживания одиночных молекул фотоактивируемые Stephan Uphoff1,2, David J. Sherratt1, Achillefs N. Kapanidis2 1Microbiology Unit, Department of Biochemistry, University of Oxford, 2Biological Physics Research Group, Clarendon Laboratory, Department of Physics, University of Oxford JoVE 51177 Immunology and Infection
Визуализация взаимодействий белок-ДНК в живых бактериальных клеток с использованием отслеживания одиночных молекул фотоактивируемые Stephan Uphoff1,2, David J. Sherratt1, Achillefs N. Kapanidis2 1Microbiology Unit, Department of Biochemistry, University of Oxford, 2Biological Physics Research Group, Clarendon Laboratory, Department of Physics, University of Oxford JoVE 51177 Immunology and Infection
