David L. Bigam Department of Surgery University of Alberta Biography Publications Institution JoVE Articles David L. Bigam has not added a biography. If you are David L. Bigam and would like to personalize this page please email our Author Liaison for assistance. Publications Milrinone is Preferred to Levosimendan for Mesenteric Perfusion in Hypoxia-reoxygenated Newborn Piglets Treated with Dopamine Pediatric Research. Mar, 2012 | Pubmed ID: 22337258 Cyclosporine Treatment Improves Mesenteric Perfusion and Attenuates Necrotizing Enterocolitis (NEC)-like Intestinal Injury in Asphyxiated Newborn Piglets During Reoxygenation Intensive Care Medicine. Dec, 2011 | Pubmed ID: 22143394 Sirolimus Drug-eluting, Hydrogel-impregnated Polypropylene Mesh Reduces Intra-abdominal Adhesion Formation in a Mouse Model Surgery. Nov, 2011 | Pubmed ID: 21943642 Effects of Tanshinone IIA, a Major Component of Salvia Miltiorrhiza, on Platelet Aggregation in Healthy Newborn Piglets Journal of Ethnopharmacology. Sep, 2011 | Pubmed ID: 21453766 The Impact of Sirolimus on Hepatitis C Recurrence After Liver Transplantation Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie. Jan, 2011 | Pubmed ID: 21258665 Improved Renal Recovery with Postresuscitation N-acetylcysteine Treatment in Asphyxiated Newborn Pigs Shock (Augusta, Ga.). Apr, 2011 | Pubmed ID: 20938377 Effects of Post-resuscitation Treatment with N-acetylcysteine on Cardiac Recovery in Hypoxic Newborn Piglets PloS One. 2010 | Pubmed ID: 21203535 Angiostatins Decrease in the Kidney of Newborn Piglets After Hypoxia-reoxygenation European Journal of Pharmacology. Oct, 2010 | Pubmed ID: 20621087 Milrinone, Dobutamine or Epinephrine Use in Asphyxiated Newborn Pigs Resuscitated with 100% Oxygen Intensive Care Medicine. Jun, 2010 | Pubmed ID: 20221750 Sirolimus-based Immunosuppression is Associated with Increased Survival After Liver Transplantation for Hepatocellular Carcinoma Hepatology (Baltimore, Md.). Apr, 2010 | Pubmed ID: 20187107 The Impact of Sirolimus on Hepatocyte Proliferation After Living Donor Liver Transplantation Clinical Transplantation. Sep-Oct, 2010 | Pubmed ID: 20002466 Cerebral Amino Acid Profiles After Hypoxia-reoxygenation and N-acetylcysteine Treatment in the Newborn Piglet Neonatology. 2010 | Pubmed ID: 19864926 Sodium Tanshinone IIA Sulfonate Increased Intestinal Hemodynamics Without Systemic Circulatory Changes in Healthy Newborn Piglets American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2009 | Pubmed ID: 19617411 The Estimated Number of Patients with Hepatocellular Carcinoma Selected for Liver Transplantation Using Expanded Selection Criteria Transplant International : Official Journal of the European Society for Organ Transplantation. Sep, 2009 | Pubmed ID: 19386075 Effects of N-acetylcysteine on Intestinal Reoxygenation Injury in Hypoxic Newborn Piglets Resuscitated with 100% Oxygen Neonatology. 2009 | Pubmed ID: 19332996 Reassessing Selection Criteria Prior to Liver Transplantation for Hepatocellular Carcinoma Utilizing the Scientific Registry of Transplant Recipients Database Hepatology (Baltimore, Md.). Mar, 2009 | Pubmed ID: 19152426 Intestinal Hemodynamic Effects of Milrinone in Asphyxiated Newborn Pigs After Reoxygenation with 100% Oxygen: a Dose-response Study Shock (Augusta, Ga.). Mar, 2009 | Pubmed ID: 18650774 Total Tumor Volume Predicts Risk of Recurrence Following Liver Transplantation in Patients with Hepatocellular Carcinoma Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Aug, 2008 | Pubmed ID: 18668667 Effects of Postresuscitation N-acetylcysteine on Cerebral Free Radical Production and Perfusion During Reoxygenation of Hypoxic Newborn Piglets Pediatric Research. Sep, 2008 | Pubmed ID: 18437097 Epinephrine Versus Dopamine to Treat Shock in Hypoxic Newborn Pigs Resuscitated with 100% Oxygen Shock (Augusta, Ga.). Feb, 2008 | Pubmed ID: 18386393 Alleviating Intestinal Ischemia-reperfusion Injury in an in Vivo Large Animal Model: Developing an Organ-specific Preservation Solution Transplantation. Mar, 2008 | Pubmed ID: 18360271 Dose-response Effects of Milrinone on Hemodynamics of Newborn Pigs with Hypoxia-reoxygenation Intensive Care Medicine. Jul, 2008 | Pubmed ID: 18357438 The Effect of Dobutamine on Platelet Aggregatory Function in Newborn Piglets with Hypoxia and Reoxygenation Shock (Augusta, Ga.). Sep, 2008 | Pubmed ID: 18323735 Cardio-renal Recovery of Hypoxic Newborn Pigs After 18%, 21% and 100% Reoxygenation Intensive Care Medicine. Jun, 2008 | Pubmed ID: 18236027 Oxidative Stress and Matrix Metalloproteinase-9 Activity in the Liver After Hypoxia and Reoxygenation with 21% or 100% Oxygen in Newborn Piglets European Journal of Pharmacology. Feb, 2008 | Pubmed ID: 18154950 Persistent Neurochemical Changes in Neonatal Piglets After Hypoxia-ischemia and Resuscitation with 100%, 21% or 18% Oxygen Resuscitation. Apr, 2008 | Pubmed ID: 18083289 The Systemic, Pulmonary and Regional Hemodynamic Recovery of Asphyxiated Newborn Piglets Resuscitated with 18%, 21% and 100% Oxygen Resuscitation. Mar, 2008 | Pubmed ID: 18022751 N-acetylcysteine Administration Improves Platelet Aggregation in Hypoxia-reoxygenation Injury Proceedings of the Western Pharmacology Society. 2007 | Pubmed ID: 18605229 The Effect of Hypoxia on Plasma Angiostatin and Related Factors in Newborn Pigs Proceedings of the Western Pharmacology Society. 2007 | Pubmed ID: 18605228 Expression of Angiostatin and Its Related Factors in the Plasma of Newborn Pigs with Hypoxia and Reoxygenation Archives of Biochemistry and Biophysics. Oct, 2007 | Pubmed ID: 17718998 N-acetylcysteine Improves the Hemodynamics and Oxidative Stress in Hypoxic Newborn Pigs Reoxygenated with 100% Oxygen Shock (Augusta, Ga.). Oct, 2007 | Pubmed ID: 17577140 ABO-incompatible Liver Transplantation for Critically Ill Adult Patients Transplant International : Official Journal of the European Society for Organ Transplantation. Aug, 2007 | Pubmed ID: 17521384 Resuscitation with 21% or 100% Oxygen is Equally Effective in Restoring Perfusion and Oxygen Metabolism in the Liver of Hypoxic Newborn Piglets Shock (Augusta, Ga.). Jun, 2007 | Pubmed ID: 17505306 De Novo Sirolimus-based Immunosuppression After Liver Transplantation for Hepatocellular Carcinoma: Long-term Outcomes and Side Effects Transplantation. May, 2007 | Pubmed ID: 17496530 Temporal Platelet Aggregatory Function in Hypoxic Newborn Piglets Reoxygenated with 18%, 21%, and 100% Oxygen Shock (Augusta, Ga.). Apr, 2007 | Pubmed ID: 17414430 Dose Response of Intravenous Sildenafil on Systemic and Regional Hemodynamics in Hypoxic Neonatal Piglets Shock (Augusta, Ga.). Jul, 2006 | Pubmed ID: 16783205 Platelet Dysfunction in Asphyxiated Newborn Piglets Resuscitated with 21% and 100% Oxygen Pediatric Research. May, 2006 | Pubmed ID: 16627873 A Dose-response Study of Graded Reoxygenation on the Carotid Haemodynamics, Matrix Metalloproteinase-2 Activities and Amino Acid Concentrations in the Brain of Asphyxiated Newborn Piglets Resuscitation. May, 2006 | Pubmed ID: 16500017 Intratracheal Administration of Sildenafil and Surfactant Alleviates the Pulmonary Hypertension in Newborn Piglets Resuscitation. May, 2006 | Pubmed ID: 16500016 Sirolimus-induced Ulceration of the Small Bowel in Islet Transplant Recipients: Report of Two Cases American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Nov, 2005 | Pubmed ID: 16212644 Strategic Opportunities in Clinical Islet Transplantation Transplantation. May, 2005 | Pubmed ID: 15912095 Organ Donation and Transplantation: a Survey of Critical Care Health Professionals in Nontransplant Hospitals Progress in Transplantation (Aliso Viejo, Calif.). Mar, 2005 | Pubmed ID: 15839375 Liver Transplantation in Severe Hepatic Trauma After Hepatic Artery Embolization The Journal of Trauma. Apr, 2005 | Pubmed ID: 15824668 Cardiac Function, Myocardial Glutathione, and Matrix Metalloproteinase-2 Levels in Hypoxic Newborn Pigs Reoxygenated by 21%, 50%, or 100% Oxygen Shock (Augusta, Ga.). Apr, 2005 | Pubmed ID: 15803064 Gastric Adenocarcinoma: Review and Considerations for Future Directions Annals of Surgery. Jan, 2005 | Pubmed ID: 15621988 Liver Trauma: Management of Devascularization Injuries The Journal of Trauma. Nov, 2004 | Pubmed ID: 15580039 Sirolimus-based Immunosuppression for Liver Transplantation in the Presence of Extended Criteria for Hepatocellular Carcinoma Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Oct, 2004 | Pubmed ID: 15376305 Pancreatic Transplantation: Beta Cell Replacement Current Treatment Options in Gastroenterology. Oct, 2004 | Pubmed ID: 15345204 Resuscitation with 100% Oxygen Causes Intestinal Glutathione Oxidation and Reoxygenation Injury in Asphyxiated Newborn Piglets Annals of Surgery. Aug, 2004 | Pubmed ID: 15273563 Association Between Surgical Margins and Long-term Outcome in Advanced Hepatoblastoma Journal of Pediatric Surgery. May, 2004 | Pubmed ID: 15137006 Human Small Bowel Storage: the Role for Luminal Preservation Solutions Transplantation. Aug, 2003 | Pubmed ID: 12973115 Percutaneous Transhepatic Pancreatic Islet Cell Transplantation in Type 1 Diabetes Mellitus: Radiologic Aspects Radiology. Oct, 2003 | Pubmed ID: 12944593 Intestinal Decontamination Using Povidone-iodine Compromises Small Bowel Storage Quality Transplantation. May, 2003 | Pubmed ID: 12792497 Defining the Role of a Tailored Luminal Solution for Small Bowel Preservation American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Mar, 2002 | Pubmed ID: 12096785 Potentiating the Benefit of Vascular-supplied Glutamine During Small Bowel Storage: Importance of Buffering Agent Transplantation. Jan, 2002 | Pubmed ID: 11821727 A Swine Model of Neonatal Asphyxia Po-Yin Cheung1, Richdeep S. Gill2, David L. Bigam2 1Departments of Pediatrics, Pharmacology and Surgery, University of Alberta, 2Department of Surgery, University of Alberta JoVE 3166 Medicine
A Swine Model of Neonatal Asphyxia Po-Yin Cheung1, Richdeep S. Gill2, David L. Bigam2 1Departments of Pediatrics, Pharmacology and Surgery, University of Alberta, 2Department of Surgery, University of Alberta JoVE 3166 Medicine