David M. Langenau Molecular Pathology, Cancer Center and Center for Regenerative Medicine Massachusetts General Hospital Biography Publications Institution JoVE Articles David M. Langenau has not added a biography. If you are David M. Langenau and would like to personalize this page please email our Author Liaison for assistance. Publications Rhabdomyosarcoma: Current Challenges and Their Implications for Developing Therapies Cold Spring Harbor Perspectives in Medicine. 2014 | Pubmed ID: 25368019 Optimized Cell Transplantation Using Adult Rag2 Mutant Zebrafish Nature Methods. Aug, 2014 | Pubmed ID: 25042784 Lineage of Origin in Rhabdomyosarcoma Informs Pharmacological Response Genes & Development. Jul, 2014 | Pubmed ID: 25030697 Zebrafish As a Model to Assess Cancer Heterogeneity, Progression and Relapse Disease Models & Mechanisms. Jul, 2014 | Pubmed ID: 24973745 Glycogen Synthase Kinase 3 Inhibitors Induce the Canonical WNT/β-catenin Pathway to Suppress Growth and Self-renewal in Embryonal Rhabdomyosarcoma Proceedings of the National Academy of Sciences of the United States of America. Apr, 2014 | Pubmed ID: 24706870 Loss of Function Tp53 Mutations Do Not Accelerate the Onset of Myc-induced T-cell Acute Lymphoblastic Leukaemia in the Zebrafish British Journal of Haematology. Jul, 2014 | Pubmed ID: 24690081 Clonal Evolution Enhances Leukemia-propagating Cell Frequency in T Cell Acute Lymphoblastic Leukemia Through Akt/mTORC1 Pathway Activation Cancer Cell. Mar, 2014 | Pubmed ID: 24613413 Pten Regulates Zebrafish Hematopoiesis Blood. Jan, 2014 | Pubmed ID: 24408201 Cross-species Array Comparative Genomic Hybridization Identifies Novel Oncogenic Events in Zebrafish and Human Embryonal Rhabdomyosarcoma PLoS Genetics. Aug, 2013 | Pubmed ID: 24009521 Zebrafish Rhabdomyosarcoma Reflects the Developmental Stage of Oncogene Expression During Myogenesis Development (Cambridge, England). Jul, 2013 | Pubmed ID: 23821038 The Histone Methyltransferase SUV39H1 Suppresses Embryonal Rhabdomyosarcoma Formation in Zebrafish PloS One. 2013 | Pubmed ID: 23705022 A Novel Chemical Screening Strategy in Zebrafish Identifies Common Pathways in Embryogenesis and Rhabdomyosarcoma Development Development (Cambridge, England). Jun, 2013 | Pubmed ID: 23615277 Through the Looking Glass: Visualizing Leukemia Growth, Migration, and Engraftment Using Fluorescent Transgenic Zebrafish Advances in Hematology. 2012 | Pubmed ID: 22829834 Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-like Effector Nucleases (TALENs) PloS One. 2012 | Pubmed ID: 22655075 In Vivo Imaging of Tumor-propagating Cells, Regional Tumor Heterogeneity, and Dynamic Cell Movements in Embryonal Rhabdomyosarcoma Cancer Cell. May, 2012 | Pubmed ID: 22624717 离散亚群的前瞻性孤立的骨胳肌细胞诱导肉瘤。 Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22135462 荧光成像研究斑马鱼的癌症。 Methods in Cell Biology. 2011 | Pubmed ID: 21951542 斑马鱼模型的横纹肌肉瘤。 Methods in Cell Biology. 2011 | Pubmed ID: 21951539 高吞吐量的成人荧光斑马鱼与 LED 荧光显微镜成像的技术。 Nature Protocols. Feb, 2011 | Pubmed ID: 21293462 选择无锌指核酸由上下文依赖程序集 (CoDA) 工程。 Nature Methods. Jan, 2011 | Pubmed ID: 21151135 T 淋巴母细胞淋巴瘤细胞表达高水平的 BCL2、 S1P1 和 ICAM1,导致肿瘤细胞术前的封锁。 Cancer Cell. Oct, 2010 | Pubmed ID: 20951945 啊 Ing 镶嵌在斑马鱼中的分析工具。 Nature Methods. Mar, 2010 | Pubmed ID: 20195251 高吞吐量细胞移植建立启动肿瘤细胞具有丰富的斑马 T 细胞急性淋巴细胞性白血病。 Blood. Apr, 2010 | Pubmed ID: 20056790 斑马鱼作为癌症的自我更新的模式。 Zebrafish. Dec, 2009 | Pubmed ID: 19954344 施工平台及应用斑马鱼阵列比较基因组杂交。 Genes, Chromosomes & Cancer. Feb, 2009 | Pubmed ID: 18973135 生成和使用不同的无处不在启动子的转基因斑马鱼线的表征。 Transgenic Research. Apr, 2008 | Pubmed ID: 17968670 热休克诱导 T 细胞淋巴瘤/白血病条件 Cre/lox 管制转基因斑马鱼。 British Journal of Haematology. Jul, 2007 | Pubmed ID: 17593023 热休克诱导的 Cre Lox 办法诱使不同类型的肿瘤和转基因斑马鱼的增生。 Proceedings of the National Academy of Sciences of the United States of America. May, 2007 | Pubmed ID: 17517602 胚胎性横纹肌肉瘤的成因对 RAS 的影响。 Genes & Development. Jun, 2007 | Pubmed ID: 17510286 条件 Myc 诱导的 T 细胞急性淋巴细胞白血病的 Cre/lox 管制转基因斑马鱼模型。 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2005 | Pubmed ID: 15827121 斑马鱼: T 细胞和胸腺发展的新模式。 Nature Reviews. Immunology. Apr, 2005 | Pubmed ID: 15803150 转基因斑马鱼的 Bcl-2 表达在淋巴组织细胞凋亡的抑制。 Blood. Apr, 2005 | Pubmed ID: 15618471 在斑马鱼及造血细胞移植拯救致命的辐射的影响。 Blood. Sep, 2004 | Pubmed ID: 15142873 T 细胞发育、 消融,和植入转基因斑马鱼的体内跟踪。 Proceedings of the National Academy of Sciences of the United States of America. May, 2004 | Pubmed ID: 15123839 斑马鱼了解免疫功能的使用。 Immunity. Apr, 2004 | Pubmed ID: 15084267 斑马鱼 Fancd2 组合式导致发育异常通过 P53 依赖的细胞凋亡。 Developmental Cell. Dec, 2003 | Pubmed ID: 14667412 转基因斑马鱼的 Myc 诱导 T 细胞白血病。 Science (New York, N.Y.). Feb, 2003 | Pubmed ID: 12574629 正常和恶性肌细胞移植到免疫受损成年斑马鱼 Inês M. Tenente*1,2,3, Qin Tang*1,2, John C. Moore1,2, David M. Langenau1,2 1Molecular Pathology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, 2Harvard Stem Cell Institute, 3GABBA - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto Immunology and Infection 量化传播肿瘤细胞的频率使用斑马鱼的同源有限稀释细胞移植 Jessica S. Blackburn1, Sali Liu1, David M. Langenau2 1Department of Molecular Pathology, Massachusetts General Hospital, Harvard Medical School, 2Department of Molecular Pathology, Massachusetts General Hospital Cancer Center, Harvard Stem Cell Institute JoVE 2790 Biology
正常和恶性肌细胞移植到免疫受损成年斑马鱼 Inês M. Tenente*1,2,3, Qin Tang*1,2, John C. Moore1,2, David M. Langenau1,2 1Molecular Pathology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, 2Harvard Stem Cell Institute, 3GABBA - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto Immunology and Infection
量化传播肿瘤细胞的频率使用斑马鱼的同源有限稀释细胞移植 Jessica S. Blackburn1, Sali Liu1, David M. Langenau2 1Department of Molecular Pathology, Massachusetts General Hospital, Harvard Medical School, 2Department of Molecular Pathology, Massachusetts General Hospital Cancer Center, Harvard Stem Cell Institute JoVE 2790 Biology