David M. Langenau Molecular Pathology, Cancer Center and Center for Regenerative Medicine Massachusetts General Hospital Biography Publications Institution JoVE Articles David M. Langenau has not added a biography. If you are David M. Langenau and would like to personalize this page please email our Author Liaison for assistance. Publications Rhabdomyosarcoma: Current Challenges and Their Implications for Developing Therapies Cold Spring Harbor Perspectives in Medicine. 2014 | Pubmed ID: 25368019 Optimized Cell Transplantation Using Adult Rag2 Mutant Zebrafish Nature Methods. Aug, 2014 | Pubmed ID: 25042784 Lineage of Origin in Rhabdomyosarcoma Informs Pharmacological Response Genes & Development. Jul, 2014 | Pubmed ID: 25030697 Zebrafish As a Model to Assess Cancer Heterogeneity, Progression and Relapse Disease Models & Mechanisms. Jul, 2014 | Pubmed ID: 24973745 Glycogen Synthase Kinase 3 Inhibitors Induce the Canonical WNT/β-catenin Pathway to Suppress Growth and Self-renewal in Embryonal Rhabdomyosarcoma Proceedings of the National Academy of Sciences of the United States of America. Apr, 2014 | Pubmed ID: 24706870 Loss of Function Tp53 Mutations Do Not Accelerate the Onset of Myc-induced T-cell Acute Lymphoblastic Leukaemia in the Zebrafish British Journal of Haematology. Jul, 2014 | Pubmed ID: 24690081 Clonal Evolution Enhances Leukemia-propagating Cell Frequency in T Cell Acute Lymphoblastic Leukemia Through Akt/mTORC1 Pathway Activation Cancer Cell. Mar, 2014 | Pubmed ID: 24613413 Pten Regulates Zebrafish Hematopoiesis Blood. Jan, 2014 | Pubmed ID: 24408201 Cross-species Array Comparative Genomic Hybridization Identifies Novel Oncogenic Events in Zebrafish and Human Embryonal Rhabdomyosarcoma PLoS Genetics. Aug, 2013 | Pubmed ID: 24009521 Zebrafish Rhabdomyosarcoma Reflects the Developmental Stage of Oncogene Expression During Myogenesis Development (Cambridge, England). Jul, 2013 | Pubmed ID: 23821038 The Histone Methyltransferase SUV39H1 Suppresses Embryonal Rhabdomyosarcoma Formation in Zebrafish PloS One. 2013 | Pubmed ID: 23705022 A Novel Chemical Screening Strategy in Zebrafish Identifies Common Pathways in Embryogenesis and Rhabdomyosarcoma Development Development (Cambridge, England). Jun, 2013 | Pubmed ID: 23615277 Through the Looking Glass: Visualizing Leukemia Growth, Migration, and Engraftment Using Fluorescent Transgenic Zebrafish Advances in Hematology. 2012 | Pubmed ID: 22829834 Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-like Effector Nucleases (TALENs) PloS One. 2012 | Pubmed ID: 22655075 In Vivo Imaging of Tumor-propagating Cells, Regional Tumor Heterogeneity, and Dynamic Cell Movements in Embryonal Rhabdomyosarcoma Cancer Cell. May, 2012 | Pubmed ID: 22624717 Sarcomi Indussero in Discreti Sottoinsiemi Di Cellule Del Muscolo Scheletrico Prospetticamente Isolato Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22135462 Fluorescente Imaging Del Cancro in Zebrafish Methods in Cell Biology. 2011 | Pubmed ID: 21951542 Modelli Di Zebrafish Di Rabdomiosarcoma Methods in Cell Biology. 2011 | Pubmed ID: 21951539 Imaging High-throughput Di Zebrafish Adulto Fluorescente Con Un LED Fluorescenza Macroscopio Nature Protocols. Feb, 2011 | Pubmed ID: 21293462 Selezione Senza Zinco-dito-nucleasi Ingegneria Assembly Dipendente Dal Contesto (CoDA) Nature Methods. Jan, 2011 | Pubmed ID: 21151135 Linfoma Linfoblastico T Cellule Esprimono Alti Livelli Di BCL2, S1P1 E ICAM1, Portando Ad Un Blocco Di Intravasation Delle Cellule Tumorali Cancer Cell. Oct, 2010 | Pubmed ID: 20951945 AMAZe-ing Strumenti Per L'analisi Del Mosaico in Zebrafish Nature Methods. Mar, 2010 | Pubmed ID: 20195251 Trapianto Di Cellule High-throughput Stabilisce Che Le Cellule Tumorali Di Avvio Sono Abbondanti in Zebrafish Leucemia Linfoblastica Acuta a Cellule T Blood. Apr, 2010 | Pubmed ID: 20056790 Zebrafish Come Modello Per Cancro Auto-rinnovamento Zebrafish. Dec, 2009 | Pubmed ID: 19954344 Costruzione E Applicazione Di Una Piattaforma Di Ibridazione Genomic Comparativa Di Matrice Zebrafish Genes, Chromosomes & Cancer. Feb, 2009 | Pubmed ID: 18973135 Generazione E Caratterizzazione Di Linee Di Zebrafish Transgenici Utilizzando Diversi Promotori Onnipresente Transgenic Research. Apr, 2008 | Pubmed ID: 17968670 Induzione Di Scossa Di Calore Della T-cellula Linfoma/leucemia Nel Condizionale Zebrafish Transgenici Cre/lox-regolato British Journal of Haematology. Jul, 2007 | Pubmed ID: 17593023 Heat Shock-inducible Cre/Lox Approcci Per Indurre Diversi Tipi Di Tumori E Iperplasia in Zebrafish Transgenici Proceedings of the National Academy of Sciences of the United States of America. May, 2007 | Pubmed ID: 17517602 Effetti Di RAS Sulla Genesi Del Rabdomiosarcoma Embrionale Genes & Development. Jun, 2007 | Pubmed ID: 17510286 Modello Zebrafish Transgenici Cre/lox-regolato Con Una Leucemia Linfoblastica Acuta Condizionale Myc-indotta Delle Cellule T Proceedings of the National Academy of Sciences of the United States of America. Apr, 2005 | Pubmed ID: 15827121 Il Danio Rerio: Un Nuovo Modello Di T-cellule E Lo Sviluppo Del Timo Nature Reviews. Immunology. Apr, 2005 | Pubmed ID: 15803150 Soppressione Dell'apoptosi Di Sovraespressione Di Bcl-2 Nelle Cellule Linfoidi Di Zebrafish Transgenici Blood. Apr, 2005 | Pubmed ID: 15618471 Effetti Dell'irradiazione Letale Di Zebrafish E Soccorso Da Trapianto Di Cellule Ematopoietiche Blood. Sep, 2004 | Pubmed ID: 15142873 Monitoraggio in Vivo Lo Sviluppo Delle Cellule T, Ablazione E Attecchimento in Zebrafish Transgenici Proceedings of the National Academy of Sciences of the United States of America. May, 2004 | Pubmed ID: 15123839 L'uso Di Zebrafish Per Capire L'immunità Immunity. Apr, 2004 | Pubmed ID: 15084267 Atterramento Di Zebrafish Fancd2 Provoca Anomalie Dello Sviluppo Tramite Apoptosi P53-dipendente Developmental Cell. Dec, 2003 | Pubmed ID: 14667412 Leucemia a Cellule T Indotta Da Myc in Zebrafish Transgenici Science (New York, N.Y.). Feb, 2003 | Pubmed ID: 12574629 Normali e maligne trapianto muscolare cellulare in immunitario compromesso Zebrafish adulti Inês M. Tenente*1,2,3, Qin Tang*1,2, John C. Moore1,2, David M. Langenau1,2 1Molecular Pathology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, 2Harvard Stem Cell Institute, 3GABBA - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto Immunology and Infection Quantificare la frequenza di tumori di moltiplicazione celle usando Limitare trapianto di cellule Diluizione in Singenico Zebrafish Jessica S. Blackburn1, Sali Liu1, David M. Langenau2 1Department of Molecular Pathology, Massachusetts General Hospital, Harvard Medical School, 2Department of Molecular Pathology, Massachusetts General Hospital Cancer Center, Harvard Stem Cell Institute JoVE 2790 Biology
Normali e maligne trapianto muscolare cellulare in immunitario compromesso Zebrafish adulti Inês M. Tenente*1,2,3, Qin Tang*1,2, John C. Moore1,2, David M. Langenau1,2 1Molecular Pathology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, 2Harvard Stem Cell Institute, 3GABBA - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto Immunology and Infection
Quantificare la frequenza di tumori di moltiplicazione celle usando Limitare trapianto di cellule Diluizione in Singenico Zebrafish Jessica S. Blackburn1, Sali Liu1, David M. Langenau2 1Department of Molecular Pathology, Massachusetts General Hospital, Harvard Medical School, 2Department of Molecular Pathology, Massachusetts General Hospital Cancer Center, Harvard Stem Cell Institute JoVE 2790 Biology