David M. Langenau Molecular Pathology, Cancer Center and Center for Regenerative Medicine Massachusetts General Hospital Biography Publications Institution JoVE Articles David M. Langenau has not added a biography. If you are David M. Langenau and would like to personalize this page please email our Author Liaison for assistance. Publications Rhabdomyosarcoma: Current Challenges and Their Implications for Developing Therapies Cold Spring Harbor Perspectives in Medicine. 2014 | Pubmed ID: 25368019 Optimized Cell Transplantation Using Adult Rag2 Mutant Zebrafish Nature Methods. Aug, 2014 | Pubmed ID: 25042784 Lineage of Origin in Rhabdomyosarcoma Informs Pharmacological Response Genes & Development. Jul, 2014 | Pubmed ID: 25030697 Zebrafish As a Model to Assess Cancer Heterogeneity, Progression and Relapse Disease Models & Mechanisms. Jul, 2014 | Pubmed ID: 24973745 Glycogen Synthase Kinase 3 Inhibitors Induce the Canonical WNT/β-catenin Pathway to Suppress Growth and Self-renewal in Embryonal Rhabdomyosarcoma Proceedings of the National Academy of Sciences of the United States of America. Apr, 2014 | Pubmed ID: 24706870 Loss of Function Tp53 Mutations Do Not Accelerate the Onset of Myc-induced T-cell Acute Lymphoblastic Leukaemia in the Zebrafish British Journal of Haematology. Jul, 2014 | Pubmed ID: 24690081 Clonal Evolution Enhances Leukemia-propagating Cell Frequency in T Cell Acute Lymphoblastic Leukemia Through Akt/mTORC1 Pathway Activation Cancer Cell. Mar, 2014 | Pubmed ID: 24613413 Pten Regulates Zebrafish Hematopoiesis Blood. Jan, 2014 | Pubmed ID: 24408201 Cross-species Array Comparative Genomic Hybridization Identifies Novel Oncogenic Events in Zebrafish and Human Embryonal Rhabdomyosarcoma PLoS Genetics. Aug, 2013 | Pubmed ID: 24009521 Zebrafish Rhabdomyosarcoma Reflects the Developmental Stage of Oncogene Expression During Myogenesis Development (Cambridge, England). Jul, 2013 | Pubmed ID: 23821038 The Histone Methyltransferase SUV39H1 Suppresses Embryonal Rhabdomyosarcoma Formation in Zebrafish PloS One. 2013 | Pubmed ID: 23705022 A Novel Chemical Screening Strategy in Zebrafish Identifies Common Pathways in Embryogenesis and Rhabdomyosarcoma Development Development (Cambridge, England). Jun, 2013 | Pubmed ID: 23615277 Through the Looking Glass: Visualizing Leukemia Growth, Migration, and Engraftment Using Fluorescent Transgenic Zebrafish Advances in Hematology. 2012 | Pubmed ID: 22829834 Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-like Effector Nucleases (TALENs) PloS One. 2012 | Pubmed ID: 22655075 In Vivo Imaging of Tumor-propagating Cells, Regional Tumor Heterogeneity, and Dynamic Cell Movements in Embryonal Rhabdomyosarcoma Cancer Cell. May, 2012 | Pubmed ID: 22624717 Sarcomas Induced in Discrete Subsets of Prospectively Isolated Skeletal Muscle Cells Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22135462 Fluorescent Imaging of Cancer in Zebrafish Methods in Cell Biology. 2011 | Pubmed ID: 21951542 Zebrafish Models of Rhabdomyosarcoma Methods in Cell Biology. 2011 | Pubmed ID: 21951539 High-throughput Imaging of Adult Fluorescent Zebrafish with an LED Fluorescence Macroscope Nature Protocols. Feb, 2011 | Pubmed ID: 21293462 Selection-free Zinc-finger-nuclease Engineering by Context-dependent Assembly (CoDA) Nature Methods. Jan, 2011 | Pubmed ID: 21151135 T-lymphoblastic Lymphoma Cells Express High Levels of BCL2, S1P1, and ICAM1, Leading to a Blockade of Tumor Cell Intravasation Cancer Cell. Oct, 2010 | Pubmed ID: 20951945 AMAZe-ing Tools for Mosaic Analysis in Zebrafish Nature Methods. Mar, 2010 | Pubmed ID: 20195251 High-throughput Cell Transplantation Establishes That Tumor-initiating Cells Are Abundant in Zebrafish T-cell Acute Lymphoblastic Leukemia Blood. Apr, 2010 | Pubmed ID: 20056790 Zebrafish As a Model for Cancer Self-renewal Zebrafish. Dec, 2009 | Pubmed ID: 19954344 Construction and Application of a Zebrafish Array Comparative Genomic Hybridization Platform Genes, Chromosomes & Cancer. Feb, 2009 | Pubmed ID: 18973135 Generation and Characterization of Transgenic Zebrafish Lines Using Different Ubiquitous Promoters Transgenic Research. Apr, 2008 | Pubmed ID: 17968670 Heat-shock Induction of T-cell Lymphoma/leukaemia in Conditional Cre/lox-regulated Transgenic Zebrafish British Journal of Haematology. Jul, 2007 | Pubmed ID: 17593023 Heat Shock-inducible Cre/Lox Approaches to Induce Diverse Types of Tumors and Hyperplasia in Transgenic Zebrafish Proceedings of the National Academy of Sciences of the United States of America. May, 2007 | Pubmed ID: 17517602 Effects of RAS on the Genesis of Embryonal Rhabdomyosarcoma Genes & Development. Jun, 2007 | Pubmed ID: 17510286 Cre/lox-regulated Transgenic Zebrafish Model with Conditional Myc-induced T Cell Acute Lymphoblastic Leukemia Proceedings of the National Academy of Sciences of the United States of America. Apr, 2005 | Pubmed ID: 15827121 The Zebrafish: a New Model of T-cell and Thymic Development Nature Reviews. Immunology. Apr, 2005 | Pubmed ID: 15803150 Suppression of Apoptosis by Bcl-2 Overexpression in Lymphoid Cells of Transgenic Zebrafish Blood. Apr, 2005 | Pubmed ID: 15618471 Effects of Lethal Irradiation in Zebrafish and Rescue by Hematopoietic Cell Transplantation Blood. Sep, 2004 | Pubmed ID: 15142873 In Vivo Tracking of T Cell Development, Ablation, and Engraftment in Transgenic Zebrafish Proceedings of the National Academy of Sciences of the United States of America. May, 2004 | Pubmed ID: 15123839 The Use of Zebrafish to Understand Immunity Immunity. Apr, 2004 | Pubmed ID: 15084267 Knockdown of Zebrafish Fancd2 Causes Developmental Abnormalities Via P53-dependent Apoptosis Developmental Cell. Dec, 2003 | Pubmed ID: 14667412 Myc-induced T Cell Leukemia in Transgenic Zebrafish Science (New York, N.Y.). Feb, 2003 | Pubmed ID: 12574629 Нормальных и злокачественных клетках мышц трансплантации в иммунной скомпрометированных взрослых данио рерио Inês M. Tenente*1,2,3, Qin Tang*1,2, John C. Moore1,2, David M. Langenau1,2 1Molecular Pathology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, 2Harvard Stem Cell Institute, 3GABBA - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto Immunology and Infection Количественная Частота опухолей, распространяющихся ячеек с использованием Ограничение трансплантации Разбавление сотовый в сингенных данио рерио Jessica S. Blackburn1, Sali Liu1, David M. Langenau2 1Department of Molecular Pathology, Massachusetts General Hospital, Harvard Medical School, 2Department of Molecular Pathology, Massachusetts General Hospital Cancer Center, Harvard Stem Cell Institute JoVE 2790 Biology
Нормальных и злокачественных клетках мышц трансплантации в иммунной скомпрометированных взрослых данио рерио Inês M. Tenente*1,2,3, Qin Tang*1,2, John C. Moore1,2, David M. Langenau1,2 1Molecular Pathology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, 2Harvard Stem Cell Institute, 3GABBA - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto Immunology and Infection
Количественная Частота опухолей, распространяющихся ячеек с использованием Ограничение трансплантации Разбавление сотовый в сингенных данио рерио Jessica S. Blackburn1, Sali Liu1, David M. Langenau2 1Department of Molecular Pathology, Massachusetts General Hospital, Harvard Medical School, 2Department of Molecular Pathology, Massachusetts General Hospital Cancer Center, Harvard Stem Cell Institute JoVE 2790 Biology
