David M. Nanus

Publications

• Circulating Tumor Cells in Prostate Cancer Diagnosis and Monitoring: An Appraisal of Clinical Potential
  Molecular Diagnosis & Therapy. May, 2014  |   Pubmed ID: 24809501
• Immunologics and Chemotherapeutics for Renal Cell Carcinoma
  Seminars in Interventional Radiology. Mar, 2014  |   Pubmed ID: 24596445
• Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
  Cancer Research. Apr, 2014  |   Pubmed ID: 24556717
• Double-blind, Randomized, Phase 2 Trial of Maintenance Sunitinib Versus Placebo After Response to Chemotherapy in Patients with Advanced Urothelial Carcinoma
  Cancer. Mar, 2014  |   Pubmed ID: 24249435
• Circulating Tumor Cells from Prostate Cancer Patients Interact with E-selectin Under Physiologic Blood Flow
  PloS One. 2013  |   Pubmed ID: 24386459
• Bone Marrow Recovery and Subsequent Chemotherapy Following Radiolabeled Anti-prostate-specific Membrane Antigen Monoclonal Antibody J591 in Men with Metastatic Castration-resistant Prostate Cancer
  Frontiers in Oncology. 2013  |   Pubmed ID: 23986881
• Phase II Study of Lutetium-177-labeled Anti-prostate-specific Membrane Antigen Monoclonal Antibody J591 for Metastatic Castration-resistant Prostate Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2013  |   Pubmed ID: 23714732
• Activation of HIF2α in Kidney Proximal Tubule Cells Causes Abnormal Glycogen Deposition but Not Tumorigenesis
  Cancer Research. May, 2013  |   Pubmed ID: 23447580
• Concurrent AURKA and MYCN Gene Amplifications Are Harbingers of Lethal Treatment-related Neuroendocrine Prostate Cancer
  Neoplasia (New York, N.Y.). Jan, 2013  |   Pubmed ID: 23358695
• 2-weekly Versus 3-weekly Docetaxel for Prostate Cancer
  The Lancet Oncology. Feb, 2013  |   Pubmed ID: 23294852
• Negative Regulation of NEP Expression by Hypoxia
  The Prostate. May, 2013  |   Pubmed ID: 23138928
• Targeted Next-generation Sequencing of Advanced Prostate Cancer Identifies Potential Therapeutic Targets and Disease Heterogeneity
  European Urology. May, 2013  |   Pubmed ID: 22981675
• Challenges in Recognizing Treatment-related Neuroendocrine Prostate Cancer
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2012  |   Pubmed ID: 23169519
• Isolation and Characterization of Circulating Tumor Cells in Prostate Cancer
  Frontiers in Oncology. 2012  |   Pubmed ID: 23087897
• Androgen Receptor on the Move: Boarding the Microtubule Expressway to the Nucleus
  Cancer Research. Sep, 2012  |   Pubmed ID: 22987486
• Adenoviral Neutral Endopeptidase Gene Delivery in Combination with Paclitaxel for the Treatment of Prostate Cancer
  International Journal of Oncology. Oct, 2012  |   Pubmed ID: 22895534
• Functional Characterization of Circulating Tumor Cells with a Prostate-cancer-specific Microfluidic Device
  PloS One. 2012  |   Pubmed ID: 22558290
• Biomarkers in the Management and Treatment of Men with Metastatic Castration-resistant Prostate Cancer
  European Urology. Mar, 2012  |   Pubmed ID: 22099611
• Molecular Characterization of Neuroendocrine Prostate Cancer and Identification of New Drug Targets
  Cancer Discovery. Nov, 2011  |   Pubmed ID: 22389870
• Generation of a Mouse Model of Von Hippel-Lindau Kidney Disease Leading to Renal Cancers by Expression of a Constitutively Active Mutant of HIF1α
  Cancer Research. Nov, 2011  |   Pubmed ID: 21908555
• Taxane-induced Blockade to Nuclear Accumulation of the Androgen Receptor Predicts Clinical Responses in Metastatic Prostate Cancer
  Cancer Research. Sep, 2011  |   Pubmed ID: 21799031
• Transitional Cell Carcinoma of the Bladder: Racial and Gender Disparities in Survival (1993 to 2002), Stage and Grade (1993 to 2007)
  The Journal of Urology. May, 2011  |   Pubmed ID: 21419456
• A Phase I Trial of Sorafenib Plus Gemcitabine and Capecitabine for Patients with Advanced Renal Cell Carcinoma: New York Cancer Consortium Trial NCI 6981
  American Journal of Clinical Oncology. Oct, 2011  |   Pubmed ID: 20881475
• Carboplatin Plus Paclitaxel Therapy After Docetaxel in Men with Metastatic Castrate Resistant Prostate Cancer
  Urologic Oncology. Nov-Dec, 2011  |   Pubmed ID: 20451413
• Phase I Trial of ATRA-IV and Depakote in Patients with Advanced Solid Tumor Malignancies
  Cancer Biology & Therapy. May, 2010  |   Pubmed ID: 20200483
• Anti-prostate-specific Membrane Antigen-based Radioimmunotherapy for Prostate Cancer
  Cancer. Feb, 2010  |   Pubmed ID: 20127956
• Is Methylation the Key to CD10 Loss?
  Journal of Pediatric Hematology/oncology. Jan, 2010  |   Pubmed ID: 20051779
• Capture of Circulating Tumor Cells from Whole Blood of Prostate Cancer Patients Using Geometrically Enhanced Differential Immunocapture (GEDI) and a Prostate-specific Antibody
  Lab on a Chip. Jan, 2010  |   Pubmed ID: 20024046
• Neutral Endopeptidase is a Myristoylated Protein
  Molecular and Cellular Biochemistry. Feb, 2010  |   Pubmed ID: 19756956
• Recent Advances in Management of Renal Cancer
  F1000 Medicine Reports. 2009  |   Pubmed ID: 20948687
• Carcinomatous Meningitis in a Patient with Her2/neu Expressing Bladder Cancer Following Trastuzumab and Chemotherapy: a Case Report and Review of the Literature
  Journal of Medical Case Reports. 2009  |   Pubmed ID: 19918289
• Synaptic Activity Reduces Intraneuronal Abeta, Promotes APP Transport to Synapses, and Protects Against Abeta-related Synaptic Alterations
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2009  |   Pubmed ID: 19657023
• Final Results of Sequential Doxorubicin Plus Gemcitabine and Ifosfamide, Paclitaxel, and Cisplatin Chemotherapy in Patients with Metastatic or Locally Advanced Transitional Cell Carcinoma of the Urothelium
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Sep, 2009  |   Pubmed ID: 19636012
• Retinoid Metabolism and ALDH1A2 (RALDH2) Expression Are Altered in the Transgenic Adenocarcinoma Mouse Prostate Model
  Biochemical Pharmacology. Nov, 2009  |   Pubmed ID: 19549509
• Rational Redesign of Neutral Endopeptidase Binding to Merlin and Moesin Proteins
  Protein Science : a Publication of the Protein Society. May, 2009  |   Pubmed ID: 19388049
• Surveillance of Urothelial Carcinoma: Stage and Grade Migration, 1993-2005 and Survival Trends, 1993-2000
  Cancer. Apr, 2009  |   Pubmed ID: 19215030
• Endothelin-1 Enhances the Expression of the Androgen Receptor Via Activation of the C-myc Pathway in Prostate Cancer Cells
  Molecular Carcinogenesis. Feb, 2009  |   Pubmed ID: 18623111
• A Phase II Study of Estramustine, Docetaxel, and Exisulind in Patients with Hormone- Refractory Prostate Cancer: Results of Cancer and Leukemia Group B Trial 90004
  Clinical Genitourinary Cancer. Sep, 2008  |   Pubmed ID: 18824434
• Inactivation of the NF2 Tumor Suppressor Protein Merlin in DU145 Prostate Cancer Cells
  The Prostate. Jun, 2008  |   Pubmed ID: 18361411
• Interaction of Prostate Specific Membrane Antigen with Clathrin and the Adaptor Protein Complex-2
  International Journal of Oncology. Nov, 2007  |   Pubmed ID: 17912448
• Phase 1/2 Clinical Trial of Interferon Alpha2b and Weekly Liposome-encapsulated All-trans Retinoic Acid in Patients with Advanced Renal Cell Carcinoma
  Journal of Immunotherapy (Hagerstown, Md. : 1997). Sep, 2007  |   Pubmed ID: 17667529
• Low Incidence of Perioperative Chemotherapy for Stage III Bladder Cancer 1998 to 2003: a Report from the National Cancer Data Base
  The Journal of Urology. Aug, 2007  |   Pubmed ID: 17561135
• Bombesin Attenuates Pre-mRNA Splicing of Glucocorticoid Receptor by Regulating the Expression of Serine-arginine Protein P30c (SRp30c) in Prostate Cancer Cells
  Biochimica Et Biophysica Acta. Jul, 2007  |   Pubmed ID: 17540466
• Trastuzumab, Paclitaxel, Carboplatin, and Gemcitabine in Advanced Human Epidermal Growth Factor Receptor-2/neu-positive Urothelial Carcinoma: Results of a Multicenter Phase II National Cancer Institute Trial
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2007  |   Pubmed ID: 17538166
• Vascular Targeted Therapy with Anti-prostate-specific Membrane Antigen Monoclonal Antibody J591 in Advanced Solid Tumors
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Feb, 2007  |   Pubmed ID: 17290063
• Clinical Relevance of Neutral Endopeptidase (NEP/CD10) in Melanoma
  Journal of Translational Medicine. 2007  |   Pubmed ID: 17207277
• Loss of Neutral Endopeptidase and Activation of Protein Kinase B (Akt) is Associated with Prostate Cancer Progression
  Cancer. Dec, 2006  |   Pubmed ID: 17083125
• Leptin Promotes Invasiveness of Murine Renal Cancer Cells Via Extracellular Signal-regulated Kinases and Rho Dependent Pathway
  The Journal of Urology. Oct, 2006  |   Pubmed ID: 16952706
• Increased Serum Leptin Levels and over Expression of Leptin Receptors Are Associated with the Invasion and Progression of Renal Cell Carcinoma
  The Journal of Urology. Oct, 2006  |   Pubmed ID: 16952705
• Multiple Androgen Response Elements Cooperate in Androgen Regulated Activity of the Type 1 Neutral Endopeptidase Promoter
  Molecular and Cellular Endocrinology. Oct, 2006  |   Pubmed ID: 16949732
• Neprilysin Inhibits Angiogenesis Via Proteolysis of Fibroblast Growth Factor-2
  The Journal of Biological Chemistry. Nov, 2006  |   Pubmed ID: 16940054
• Chemotherapy for Non-clear-cell Renal Cell Carcinoma
  Clinical Genitourinary Cancer. Mar, 2006  |   Pubmed ID: 16729909
• Clinical Utility of Radiolabeled Monoclonal Antibodies in Prostate Cancer
  Clinical Genitourinary Cancer. Mar, 2006  |   Pubmed ID: 16729907
• Decreased Expression of the Human Stem Cell Marker, Rex-1 (zfp-42), in Renal Cell Carcinoma
  Carcinogenesis. Mar, 2006  |   Pubmed ID: 16344273
• Antibody-based Therapeutics: Focus on Prostate Cancer
  Cancer Metastasis Reviews. Dec, 2005  |   Pubmed ID: 16408160
• Radioimmunotherapy of Prostate Cancer Using 90Y- and 177Lu-labeled J591 Monoclonal Antibodies: Effect of Multiple Treatments on Myelotoxicity
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2005  |   Pubmed ID: 16203821
• Involvement of Neutral Endopeptidase in Neoplastic Progression
  Biochimica Et Biophysica Acta. Aug, 2005  |   Pubmed ID: 16054017
• Prediction of Myelotoxicity Based on Bone Marrow Radiation-absorbed Dose: Radioimmunotherapy Studies Using 90Y- and 177Lu-labeled J591 Antibodies Specific for Prostate-specific Membrane Antigen
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. May, 2005  |   Pubmed ID: 15872360
• Retinoic Acid and the Histone Deacetylase Inhibitor Trichostatin a Inhibit the Proliferation of Human Renal Cell Carcinoma in a Xenograft Tumor Model
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2005  |   Pubmed ID: 15867260
• Phase I Trial of 177lutetium-labeled J591, a Monoclonal Antibody to Prostate-specific Membrane Antigen, in Patients with Androgen-independent Prostate Cancer
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jul, 2005  |   Pubmed ID: 15837970
• Pharmacokinetics and Biodistribution of 111In- and 177Lu-labeled J591 Antibody Specific for Prostate-specific Membrane Antigen: Prediction of 90Y-J591 Radiation Dosimetry Based on 111In or 177Lu?
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Apr, 2005  |   Pubmed ID: 15809486
• Retinoid Receptor MRNA Expression Profiles in Human Bladder Cancer Specimens
  International Journal of Oncology. Apr, 2005  |   Pubmed ID: 15754000
• Active Chemotherapy for Sarcomatoid and Rapidly Progressing Renal Cell Carcinoma
  Cancer. Oct, 2004  |   Pubmed ID: 15378501
• Neutral Endopeptidase Protein Expression and Prognosis in Localized Prostate Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2004  |   Pubmed ID: 15217945
• Phase I Trial of Yttrium-90-labeled Anti-prostate-specific Membrane Antigen Monoclonal Antibody J591 for Androgen-independent Prostate Cancer
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jul, 2004  |   Pubmed ID: 15173215
• Reduced Lecithin: Retinol Acyltransferase Expression Correlates with Increased Pathologic Tumor Stage in Bladder Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2004  |   Pubmed ID: 15161698
• Aminopeptidase A is a Functional Target in Angiogenic Blood Vessels
  Cancer Cell. Feb, 2004  |   Pubmed ID: 14998491
• Synergy in Tumor Suppression by Direct Interaction of Neutral Endopeptidase with PTEN
  Cancer Cell. Jan, 2004  |   Pubmed ID: 14749127
• Chemosensitization of Androgen-independent Prostate Cancer with Neutral Endopeptidase
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2004  |   Pubmed ID: 14734478
• Direct Binding of Neutral Endopeptidase 24.11 to Ezrin/radixin/moesin (ERM) Proteins Competes with the Interaction of CD44 with ERM Proteins
  The Journal of Biological Chemistry. Mar, 2004  |   Pubmed ID: 14704146
• Of Peptides and Peptidases: the Role of Cell Surface Peptidases in Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2003  |   Pubmed ID: 14695128
• Clinical Use of Monoclonal Antibody HuJ591 Therapy: Targeting Prostate Specific Membrane Antigen
  The Journal of Urology. Dec, 2003  |   Pubmed ID: 14610416
• Third International Conference on Innovations and Challenges in Prostate Cancer: Prevention, Detection and Treatment
  The Journal of Urology. Dec, 2003  |   Pubmed ID: 14610403
• Differential Expression of the Enzyme That Esterifies Retinol, Lecithin:retinol Acyltransferase, in Subtypes of Human Renal Cancer and Normal Kidney
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2003  |   Pubmed ID: 14581364
• Targeted Systemic Therapy of Prostate Cancer with a Monoclonal Antibody to Prostate-specific Membrane Antigen
  Seminars in Oncology. Oct, 2003  |   Pubmed ID: 14571414
• Targeting Metastatic Prostate Cancer with Radiolabeled Monoclonal Antibody J591 to the Extracellular Domain of Prostate Specific Membrane Antigen
  The Journal of Urology. Nov, 2003  |   Pubmed ID: 14532761
• Chemotherapeutic Strategies for Renal Cell Carcinoma
  The Urologic Clinics of North America. Aug, 2003  |   Pubmed ID: 12953758
• Detection of the P110 Beta Subunit of Phosphatidylinositol 3-kinase Complexed with Neutral Endopeptidase
  Anticancer Research. Sep-Oct, 2002  |   Pubmed ID: 12529960
• High Expression of the Met Receptor in Prostate Cancer Metastasis to Bone
  Urology. Dec, 2002  |   Pubmed ID: 12475693
• Phase I Trial of Interferon Alpha2b and Liposome-encapsulated All-trans Retinoic Acid in the Treatment of Patients with Advanced Renal Cell Carcinoma
  Cancer. Sep, 2002  |   Pubmed ID: 12216088
• The Utility of Monoclonal Antibodies in the Imaging of Prostate Cancer
  Seminars in Urologic Oncology. Aug, 2002  |   Pubmed ID: 12215974
• Estramustine Plus a Taxane for Advanced Prostate Cancer: the New Standard Therapy?
  Cancer Investigation. 2002  |   Pubmed ID: 12197243
• Synergistic Activation of the Androgen Receptor by Bombesin and Low-dose Androgen
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2002  |   Pubmed ID: 12114445
• Retinol Metabolism and Lecithin:retinol Acyltransferase Levels Are Reduced in Cultured Human Prostate Cancer Cells and Tissue Specimens
  Cancer Research. Mar, 2002  |   Pubmed ID: 11912136
• Active Chemotherapy for Collecting Duct Carcinoma of the Kidney: a Case Report and Review of the Literature
  Cancer. Jan, 2002  |   Pubmed ID: 11815966