David T. Scadden Biography Publications JoVE Articles David T. Scadden has not added a biography. If you are David T. Scadden and would like to personalize this page please email our Author Liaison for assistance. Publications Health Consequences of Thymus Removal in Adults. Reply The New England Journal of Medicine. Nov, 2023 | Pubmed ID: 37913517 Clearing and Replacing Tissue-resident Myeloid Cells with an Anti-CD45 Antibody-drug Conjugate Blood Advances. Nov, 2023 | Pubmed ID: 37748049 Adult Prg4+ Progenitors Repair Long-term Articular Cartilage Wounds in Vivo JCI Insight. Sep, 2023 | Pubmed ID: 37681409 PPM1D Modulates Hematopoietic Cell Fitness and Response to DNA Damage and is a Therapeutic Target in Myeloid Malignancy Blood. Dec, 2023 | Pubmed ID: 37595362 Health Consequences of Thymus Removal in Adults The New England Journal of Medicine. Aug, 2023 | Pubmed ID: 37530823 The Bone Marrow Stroma in Human Myelodysplastic Syndrome Reveals Alterations That Regulate Disease Progression Blood Advances. Nov, 2023 | Pubmed ID: 37450380 Limited Plasticity of Monocyte Fate and Function Associated with Epigenetic Scripting at the Level of Progenitors Blood. Aug, 2023 | Pubmed ID: 37267513 Dissecting the Immune Suppressive Human Prostate Tumor Microenvironment Via Integrated Single-cell and Spatial Transcriptomic Analyses Nature Communications. Feb, 2023 | Pubmed ID: 36750562 Immune-responsive Biodegradable Scaffolds for Enhancing Neutrophil Regeneration Bioengineering & Translational Medicine. Jan, 2023 | Pubmed ID: 36684088 Isolation of Thymus Stromal Cells from Human and Murine Tissue Methods in Molecular Biology (Clifton, N.J.). 2023 | Pubmed ID: 36255703 Image-seq: Spatially Resolved Single-cell Sequencing Guided by in Situ and in Vivo Imaging Nature Methods. Dec, 2022 | Pubmed ID: 36424441 Defocus Corrected Large Area Cryo-EM (DeCo-LACE) for Label-free Detection of Molecules Across Entire Cell Sections ELife. Nov, 2022 | Pubmed ID: 36382886 A Transcriptional Metastatic Signature Predicts Survival in Clear Cell Renal Cell Carcinoma Nature Communications. Sep, 2022 | Pubmed ID: 36180422 Sleep Exerts Lasting Effects on Hematopoietic Stem Cell Function and Diversity The Journal of Experimental Medicine. Nov, 2022 | Pubmed ID: 36129517 Recent Advances in "sickle and Niche" Research - Tribute to Dr. Paul S Frenette Stem Cell Reports. Jul, 2022 | Pubmed ID: 35830837 In Vivo Genome-wide CRISPR Screening in Murine Acute Myeloid Leukemia Uncovers Microenvironmental Dependencies Blood Advances. Sep, 2022 | Pubmed ID: 35793392 Bone Marrow Endothelial Dysfunction Promotes Myeloid Cell Expansion in Cardiovascular Disease Nature Cardiovascular Research. Jan, 2022 | Pubmed ID: 35747128 Author Correction: B Lymphocyte-derived Acetylcholine Limits Steady-state and Emergency Hematopoiesis Nature Immunology. Aug, 2022 | Pubmed ID: 35705799 B Lymphocyte-derived Acetylcholine Limits Steady-state and Emergency Hematopoiesis Nature Immunology. Apr, 2022 | Pubmed ID: 35352063 Proton Export Alkalinizes Intracellular PH and Reprograms Carbon Metabolism to Drive Normal and Malignant Cell Growth Blood. Jan, 2022 | Pubmed ID: 34610101 What is the Role of the Bone Marrow Microenvironment in AML? Best Practice & Research. Clinical Haematology. Dec, 2021 | Pubmed ID: 34865700 Low NCOR2 Levels in Multiple Myeloma Patients Drive Multidrug Resistance Via MYC Upregulation Blood Cancer Journal. Dec, 2021 | Pubmed ID: 34864816 Chromatin-state Barriers Enforce an Irreversible Mammalian Cell Fate Decision Cell Reports. Nov, 2021 | Pubmed ID: 34758323 Analysis of Leukemia Cell Metabolism Through Stable Isotope Tracing in Mice Bio-protocol. Oct, 2021 | Pubmed ID: 34722818 Human Prostate Cancer Bone Metastases Have an Actionable Immunosuppressive Microenvironment Cancer Cell. Nov, 2021 | Pubmed ID: 34719426 Author Correction: An Injectable Bone Marrow-like Scaffold Enhances T Cell Immunity After Hematopoietic Stem Cell Transplantation Nature Biotechnology. Nov, 2021 | Pubmed ID: 34663922 TiRNA Signaling Via Stress-regulated Vesicle Transfer in the Hematopoietic Niche Cell Stem Cell. Dec, 2021 | Pubmed ID: 34551362 In Memory of Paul Sylvain Frenette, a Pioneering Explorer of the Hematopoietic Stem Cell Niche Who Left Far Too Early Experimental Hematology. Aug, 2021 | Pubmed ID: 34403758 Metabolic Perturbations Sensitize Triple-negative Breast Cancers to Apoptosis Induced by BH3 Mimetics Science Signaling. Jun, 2021 | Pubmed ID: 34103421 Malic Enzyme 2 Connects the Krebs Cycle Intermediate Fumarate to Mitochondrial Biogenesis Cell Metabolism. May, 2021 | Pubmed ID: 33770508 Young Haematopoietic Stem Cells Are Picky Eaters Cell Research. Apr, 2021 | Pubmed ID: 33633351 Imaging Dynamic MTORC1 Pathway Activity in Vivo Reveals Marked Shifts That Support Time-specific Inhibitor Therapy in AML Nature Communications. Jan, 2021 | Pubmed ID: 33431855 Progression Signature Underlies Clonal Evolution and Dissemination of Multiple Myeloma Blood. Apr, 2021 | Pubmed ID: 33150374 Efficacy and Safety of Anti-CD45-saporin As Conditioning Agent for RAG Deficiency The Journal of Allergy and Clinical Immunology. Jan, 2021 | Pubmed ID: 32387109 Lactate Dehydrogenase A Governs Cardiac Hypertrophic Growth in Response to Hemodynamic Stress Cell Reports. Sep, 2020 | Pubmed ID: 32877669 Cell Interactions in the Bone Marrow Microenvironment Affecting Myeloid Malignancies Blood Advances. Aug, 2020 | Pubmed ID: 32780848 Adult Blood Stem Cell Localization Reflects the Abundance of Reported Bone Marrow Niche Cell Types and Their Combinations Blood. Nov, 2020 | Pubmed ID: 32766876 Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance Cell Metabolism. Sep, 2020 | Pubmed ID: 32763164 C9orf72 Suppresses Systemic and Neural Inflammation Induced by Gut Bacteria Nature. Jun, 2020 | Pubmed ID: 32483373 Aldehyde Dehydrogenase 3a2 Protects AML Cells from Oxidative Death and the Synthetic Lethality of Ferroptosis Inducers Blood. Sep, 2020 | Pubmed ID: 32458004 Lipid Availability Determines Fate of Skeletal Progenitor Cells Via SOX9 Nature. Mar, 2020 | Pubmed ID: 32103177 A Biomaterial-based Vaccine Eliciting Durable Tumour-specific Responses Against Acute Myeloid Leukaemia Nature Biomedical Engineering. Jan, 2020 | Pubmed ID: 31937942 Metcalf Lecture Award: Applying Niche Biology to Engineer T-cell Regenerative Therapies Experimental Hematology. Dec, 2019 | Pubmed ID: 31765673 Exercise Reduces Inflammatory Cell Production and Cardiovascular Inflammation Via Instruction of Hematopoietic Progenitor Cells Nature Medicine. Nov, 2019 | Pubmed ID: 31700184 Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed Through Single-Cell Protein Expression Mapping Cell Stem Cell. Oct, 2019 | Pubmed ID: 31279774 A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia Cell. Jun, 2019 | Pubmed ID: 31130381 Lineage Tracing Reveals a Subset of Reserve Muscle Stem Cells Capable of Clonal Expansion Under Stress Cell Stem Cell. Jun, 2019 | Pubmed ID: 31006621 The Novel Dihydroorotate Dehydrogenase (DHODH) Inhibitor BAY 2402234 Triggers Differentiation and is Effective in the Treatment of Myeloid Malignancies Leukemia. Oct, 2019 | Pubmed ID: 30940908 Ptpn21 Controls Hematopoietic Stem Cell Homeostasis and Biomechanics Cell Stem Cell. Apr, 2019 | Pubmed ID: 30880025 Glucocorticoids Regulate Bone Marrow B Lymphopoiesis After Stroke Circulation Research. Apr, 2019 | Pubmed ID: 30782088 An Injectable Bone Marrow-like Scaffold Enhances T Cell Immunity After Hematopoietic Stem Cell Transplantation Nature Biotechnology. Mar, 2019 | Pubmed ID: 30742125 Selective Hematopoietic Stem Cell Ablation Using CD117-antibody-drug-conjugates Enables Safe and Effective Transplantation with Immunity Preservation Nature Communications. Feb, 2019 | Pubmed ID: 30728354 Cell Cycle Analysis of Hematopoietic Stem and Progenitor Cells by Multicolor Flow Cytometry Current Protocols in Cytometry. Jan, 2019 | Pubmed ID: 30335223 Modulating Bone Marrow Hematopoietic Lineage Potential to Prevent Bone Metastasis in Breast Cancer Cancer Research. Sep, 2018 | Pubmed ID: 30065048 DropEst: Pipeline for Accurate Estimation of Molecular Counts in Droplet-based Single-cell RNA-seq Experiments Genome Biology. Jun, 2018 | Pubmed ID: 29921301 The NOTCH1/CD44 Axis Drives Pathogenesis in a T Cell Acute Lymphoblastic Leukemia Model The Journal of Clinical Investigation. Jul, 2018 | Pubmed ID: 29781813 Deficiency-induced Bone Marrow Niche Alterations Lead to the Initiation of Myeloproliferative Neoplasm Blood Advances. Mar, 2018 | Pubmed ID: 29514790 Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell Cell. Jan, 2018 | Pubmed ID: 29224778 Bone Marrow Drives Central Nervous System Regeneration After Radiation Injury The Journal of Clinical Investigation. Jan, 2018 | Pubmed ID: 29202481 Osteoblasts Remotely Supply Lung Tumors with Cancer-promoting SiglecF Neutrophils Science (New York, N.Y.). Dec, 2017 | Pubmed ID: 29191879 The Metabolic Regulator MTORC1 Controls Terminal Myeloid Differentiation Science Immunology. May, 2017 | Pubmed ID: 28763796 ZFP521 Regulates Murine Hematopoietic Stem Cell Function and Facilitates MLL-AF9 Leukemogenesis in Mouse and Human Cells Blood. Aug, 2017 | Pubmed ID: 28615219 Hematopoiesis: Reconciling Historic Controversies About the Niche Cell Stem Cell. May, 2017 | Pubmed ID: 28475884 Shipping Mouse Bone Marrow: Keep It in the Bone Experimental Hematology. May, 2017 | Pubmed ID: 28043821 Bone Marrow-derived Immature Myeloid Cells Are a Main Source of Circulating SuPAR Contributing to Proteinuric Kidney Disease Nature Medicine. Jan, 2017 | Pubmed ID: 27941791 Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia ACS Medicinal Chemistry Letters. Dec, 2016 | Pubmed ID: 27994748 Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells Cell. Nov, 2016 | Pubmed ID: 27863245 Leukaemogenic Effects of Ptpn11 Activating Mutations in the Stem Cell Microenvironment Nature. Nov, 2016 | Pubmed ID: 27783593 Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia Cell. Sep, 2016 | Pubmed ID: 27641501 PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation Via Deactivation of ACC2 Molecular Cell. Sep, 2016 | Pubmed ID: 27635760 Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators Cell Stem Cell. Oct, 2016 | Pubmed ID: 27524439 Angiogenin Promotes Hematopoietic Regeneration by Dichotomously Regulating Quiescence of Stem and Progenitor Cells Cell. Aug, 2016 | Pubmed ID: 27518564 Distinctive Mesenchymal-Parenchymal Cell Pairings Govern B Cell Differentiation in the Bone Marrow Stem Cell Reports. Aug, 2016 | Pubmed ID: 27453006 Non-genotoxic Conditioning for Hematopoietic Stem Cell Transplantation Using a Hematopoietic-cell-specific Internalizing Immunotoxin Nature Biotechnology. Jul, 2016 | Pubmed ID: 27272386 Hematopoietic Stem Cell Niche in Health and Disease Annual Review of Pathology. May, 2016 | Pubmed ID: 27193455 Single Targeted Exon Mutation Creates a True Congenic Mouse for Competitive Hematopoietic Stem Cell Transplantation: The C57BL/6-CD45.1(STEM) Mouse Stem Cell Reports. Jun, 2016 | Pubmed ID: 27185283 Heterogeneity of the Bone Marrow Niche Current Opinion in Hematology. Jul, 2016 | Pubmed ID: 27177311 Blood and Bone The New England Journal of Medicine. May, 2016 | Pubmed ID: 27168440 Hematopoietic Stem Cell and Its Bone Marrow Niche Current Topics in Developmental Biology. 2016 | Pubmed ID: 27137653 Distinct Bone Marrow Blood Vessels Differentially Regulate Haematopoiesis Nature. Apr, 2016 | Pubmed ID: 27074509 Tle1 Tumor Suppressor Negatively Regulates Inflammation in Vivo and Modulates NF-κB Inflammatory Pathway Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26831087 Targeting the Warburg Effect for Leukemia Therapy: Magnitude Matters Molecular & Cellular Oncology. 2015 | Pubmed ID: 27308458 Not All Created Equal: Lineage Hard-Wiring in the Production of Blood Cell. Dec, 2015 | Pubmed ID: 26687347 A Hostel for the Hostile: the Bone Marrow Niche in Hematologic Neoplasms Haematologica. Nov, 2015 | Pubmed ID: 26521296 Transcriptome Comparison of Distinct Osteolineage Subsets in the Hematopoietic Stem Cell Niche Using a Triple Fluorescent Transgenic Mouse Model Genomics Data. Sep, 2015 | Pubmed ID: 26484277 Global Transcriptome Analysis of T-competent Progenitors in the Bone Marrow Genomics Data. Sep, 2015 | Pubmed ID: 26484235 Engineering Pulmonary Vasculature in Decellularized Rat and Human Lungs Nature Biotechnology. Oct, 2015 | Pubmed ID: 26368048 Harnessing the Apoptotic Programs in Cancer Stem-like Cells EMBO Reports. Sep, 2015 | Pubmed ID: 26253117 Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells Cell Stem Cell. May, 2015 | Pubmed ID: 25957903 Specific Bone Cells Produce DLL4 to Generate Thymus-seeding Progenitors from Bone Marrow The Journal of Experimental Medicine. May, 2015 | Pubmed ID: 25918341 Notch Receptor-Ligand Engagement Maintains Hematopoietic Stem Cell Quiescence and Niche Retention Stem Cells (Dayton, Ohio). Apr, 2015 | Pubmed ID: 25851125 Mesenchymal Cell Contributions to the Stem Cell Niche Cell Stem Cell. Mar, 2015 | Pubmed ID: 25748931 Bayesian Approach to Single-cell Differential Expression Analysis Nature Methods. May, 2014 | Pubmed ID: 24836921 Tic-TACs: Refreshing Hair Growth Cell. May, 2014 | Pubmed ID: 24813602 Nice Neighborhood: Emerging Concepts of the Stem Cell Niche Cell. Mar, 2014 | Pubmed ID: 24679525 Direct Measurement of Local Oxygen Concentration in the Bone Marrow of Live Animals Nature. Apr, 2014 | Pubmed ID: 24590072 Bone's Dark Side: Mutated Osteoblasts Implicated in Leukemia Cell Research. Apr, 2014 | Pubmed ID: 24589711 Stress Hematopoiesis is Regulated by the Krüppel-like Transcription Factor ZBP-89 Stem Cells (Dayton, Ohio). Mar, 2014 | Pubmed ID: 24549639 The Bone Marrow Niche for Haematopoietic Stem Cells Nature. Jan, 2014 | Pubmed ID: 24429631 Genome-wide Map of Nuclear Protein Degradation Shows NCoR1 Turnover As a Key to Mitochondrial Gene Regulation Cell. Dec, 2013 | Pubmed ID: 24315104 Blood Scent Cell. Nov, 2013 | Pubmed ID: 24267883 Correction: Tracking Single Cells in Live Animals Using a Photoconvertible Near-Infrared Cell Membrane Label PloS One. 2013 | Pubmed ID: 24250779 Modeling Human Hematopoietic Stem Cell Biology in the Mouse Seminars in Hematology. Apr, 2013 | Pubmed ID: 24216169 Sox4 is a Key Oncogenic Target in C/EBPα Mutant Acute Myeloid Leukemia Cancer Cell. Nov, 2013 | Pubmed ID: 24183681 Differential Regulation of Myeloid Leukemias by the Bone Marrow Microenvironment Nature Medicine. Nov, 2013 | Pubmed ID: 24162813 Niche-based Screening Identifies Small-molecule Inhibitors of Leukemia Stem Cells Nature Chemical Biology. Dec, 2013 | Pubmed ID: 24161946 Prostaglandin-modulated Umbilical Cord Blood Hematopoietic Stem Cell Transplantation Blood. Oct, 2013 | Pubmed ID: 23996087 Tracking Single Cells in Live Animals Using a Photoconvertible Near-infrared Cell Membrane Label PloS One. 2013 | Pubmed ID: 23990881 Generation of Functionally Competent and Durable Engineered Blood Vessels from Human Induced Pluripotent Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Jul, 2013 | Pubmed ID: 23861493 In Vivo RNAi Screening Identifies a Leukemia-specific Dependence on Integrin Beta 3 Signaling Cancer Cell. Jul, 2013 | Pubmed ID: 23770013 Influenza, but Not HIV-specific CTL Epitopes, Elicits Delayed-type Hypersensitivity (DTH) Reactions in HIV-infected Patients European Journal of Immunology. Jun, 2013 | Pubmed ID: 23504637 Differential Stem- and Progenitor-cell Trafficking by Prostaglandin E2 Nature. Mar, 2013 | Pubmed ID: 23485965 BM Mesenchymal Stromal Cell-derived Exosomes Facilitate Multiple Myeloma Progression The Journal of Clinical Investigation. Apr, 2013 | Pubmed ID: 23454749 Xist RNA is a Potent Suppressor of Hematologic Cancer in Mice Cell. Feb, 2013 | Pubmed ID: 23415223 SIRT3 Reverses Aging-associated Degeneration Cell Reports. Feb, 2013 | Pubmed ID: 23375372 The Hematopoietic Stem Cell Niche--home for Friend and Foe? Cytometry. Part B, Clinical Cytometry. Jan-Feb, 2013 | Pubmed ID: 23281119 Myelopoiesis is Regulated by Osteocytes Through Gsα-dependent Signaling Blood. Feb, 2013 | Pubmed ID: 23160461 Advances in the Biology and Therapy of Chronic Myeloid Leukemia: Proceedings from the 6th Post-ASH International Chronic Myeloid Leukemia and Myeloproliferative Neoplasms Workshop Leukemia & Lymphoma. Jun, 2013 | Pubmed ID: 23121619 Fate Through Fat: Lipid Metabolism Determines Stem Cell Division Outcome Cell Metabolism. Oct, 2012 | Pubmed ID: 23040066 Complex Oncogene Dependence in MicroRNA-125a-induced Myeloproliferative Neoplasms Proceedings of the National Academy of Sciences of the United States of America. Oct, 2012 | Pubmed ID: 23012470 MTOR Complex 1 Plays Critical Roles in Hematopoiesis and Pten-loss-evoked Leukemogenesis Cell Stem Cell. Sep, 2012 | Pubmed ID: 22958934 The Stem Cell Niche: Tissue Physiology at a Single Cell Level The Journal of Clinical Investigation. Sep, 2012 | Pubmed ID: 22945635 Cancers Predispose Neutrophils to Release Extracellular DNA Traps That Contribute to Cancer-associated Thrombosis Proceedings of the National Academy of Sciences of the United States of America. Aug, 2012 | Pubmed ID: 22826226 Rethinking Stroma: Lessons from the Blood Cell Stem Cell. Jun, 2012 | Pubmed ID: 22704500 The Secrets of the Bone Marrow Niche: Metabolic Priming for AML Nature Medicine. Jun, 2012 | Pubmed ID: 22673998 Deconstructing the Complexity of a Microenvironmental Niche Cell. Mar, 2012 | Pubmed ID: 22464318 A Randomized Controlled Trial of Highly Active Antiretroviral Therapy Versus Highly Active Antiretroviral Therapy and Chemotherapy in Therapy-naive Patients with HIV-associated Kaposi Sarcoma in South Africa Journal of Acquired Immune Deficiency Syndromes (1999). Jun, 2012 | Pubmed ID: 22395672 Endogenous Bone Marrow MSCs Are Dynamic, Fate-restricted Participants in Bone Maintenance and Regeneration Cell Stem Cell. Mar, 2012 | Pubmed ID: 22385654 造血干细胞龛。 Frontiers in Bioscience : a Journal and Virtual Library. 2012 | Pubmed ID: 22201730 十字路口的血液和免疫功能的骨髓。 Nature Reviews. Immunology. Jan, 2012 | Pubmed ID: 22193770 NF-Y 是造血干细胞增殖和生存所必需的。 Blood. Feb, 2012 | Pubmed ID: 22072554 造血干细胞龛一眼。 Journal of Cell Science. Nov, 2011 | Pubmed ID: 22083139 糖尿病通过改变生态位功能损害造血干细胞动员。 Science Translational Medicine. Oct, 2011 | Pubmed ID: 21998408 AKT/FOXO 信号强制使用可逆分化封锁在髓系白血病。 Cell. Sep, 2011 | Pubmed ID: 21884932 微分生态位和 Wnt 要求在急性髓细胞白血病的研究进展。 Blood. Sep, 2011 | Pubmed ID: 21765021 活体成像的 Treg 细胞对造血干细胞龛提供免疫特权。 Nature. Jun, 2011 | Pubmed ID: 21654805 凹槽和 AKT 信号在小鼠巨核细胞沿袭规范之间的串扰。 Blood. Aug, 2011 | Pubmed ID: 21653327 鸟嘌呤核苷酸交换因子 Vav1 调节造血干祖细胞的血管周围自导和骨髓保留。 Proceedings of the National Academy of Sciences of the United States of America. Jun, 2011 | Pubmed ID: 21606370 骨形态发生蛋白信号转导抑制抑制与炎症相关的贫血。 Blood. May, 2011 | Pubmed ID: 21393479 人类干细胞研究的仿生平台。 Cell Stem Cell. Mar, 2011 | Pubmed ID: 21362565 鼠标颅骨骨髓移植造血干、 祖细胞的活体成像。 Nature Protocols. Jan, 2011 | Pubmed ID: 21212779 Lkb1 代谢传感器保持造血干细胞存活。 Nature. Dec, 2010 | Pubmed ID: 21124451 MicroRNA 调控成人造血干细胞。 Cell Cycle (Georgetown, Tex.). Sep, 2010 | Pubmed ID: 20855952 骨髓间充质和造血干细胞形成一个独特的骨髓利基市场。 Nature. Aug, 2010 | Pubmed ID: 20703299 干细胞和 DNA 的损害: 坚持还是灭亡吗? Cell. Aug, 2010 | Pubmed ID: 20691895 维生素 D 受体删除会导致增加造血干祖细胞和居住在脾。 Blood. Nov, 2010 | Pubmed ID: 20664059 MicroRNA 和平号空间站 125a 控制造血干细胞数量。 Proceedings of the National Academy of Sciences of the United States of America. Aug, 2010 | Pubmed ID: 20616003 HSC 生态位概念已打开 31。我们的知识已经成熟吗? Annals of the New York Academy of Sciences. Mar, 2010 | Pubmed ID: 20392212 骨祖功能障碍诱导骨髓和辅助白血病。 Nature. Apr, 2010 | Pubmed ID: 20305640 激活素 A 促进致多发性骨髓瘤骨溶解,发性骨髓瘤骨疾病很有希望的目标。 Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010 | Pubmed ID: 20194748 CD133 表达式定义启动细胞人口主要人类卵巢癌肿瘤。 Stem Cells (Dayton, Ohio). Dec, 2009 | Pubmed ID: 19816957 VEGFR2 + PDGFRbeta + 循环前体细胞参与毛细管高氧急性肺损伤 (哈尼族) 后恢复。 Journal of Cellular and Molecular Medicine. Sep, 2009 | Pubmed ID: 19426150 白血病干细胞的利基: 当前概念和治疗机会。 Blood. Aug, 2009 | Pubmed ID: 19401558 P27Kip1 约束恒久和缺血条件下成人脑内的神经祖细胞的增殖。 Stem Cells (Dayton, Ohio). Apr, 2009 | Pubmed ID: 19353520 造血干细胞的取决于 Galpha(s)-介导的信号来嫁接骨髓。 Nature. May, 2009 | Pubmed ID: 19322176 成骨细胞在骨髓造血龛位沿袭的作用。 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. May, 2009 | Pubmed ID: 19257832 转发中主要人类造血干/祖细胞 RNAi 屏幕。 Blood. Apr, 2009 | Pubmed ID: 19188664 生活动物跟踪单个造血干/祖细胞的一席之地。 Nature. Jan, 2009 | Pubmed ID: 19052546 将干细胞最后交付吗? Newsweek. Dec, 2008 | Pubmed ID: 19105310 内分为: 成人干细胞池内的差异。 Cell. Dec, 2008 | Pubmed ID: 19070570 B 骨量的成骨细胞调控介导的 Gs {字母}-依赖的信号通路。 Proceedings of the National Academy of Sciences of the United States of America. Nov, 2008 | Pubmed ID: 18957542 神经系统-2 规定了粒细胞-巨噬细胞祖细胞功能。 Blood. Dec, 2008 | Pubmed ID: 18840712 Nf2/梅林调节造血干细胞行为通过改变微环境的体系结构。 Cell Stem Cell. Aug, 2008 | Pubmed ID: 18682243 巨核细胞红细胞的祖细胞的细胞命运的 MicroRNA 介导的控件。 Developmental Cell. Jun, 2008 | Pubmed ID: 18539114 演变中的造血干细胞微环境生态位的理念。 Current Opinion in Hematology. Jul, 2008 | Pubmed ID: 18536566 造血干细胞对外源性信号的响应能力受半胱氨酸蛋白酶-3 的限制。 Cell Stem Cell. Jun, 2008 | Pubmed ID: 18522851 微分 H3K4 甲基化标识发育蓄势待发造血基因。 Developmental Cell. May, 2008 | Pubmed ID: 18477461 肿瘤坏死因子和血管内皮细胞调节 Notch 信号在骨髓微环境中,在炎症过程。 Experimental Hematology. May, 2008 | Pubmed ID: 18439488 干细胞生态学与干细胞的议案。 Blood. Apr, 2008 | Pubmed ID: 18398055 Wnt 通路的利基强制实施造血干细胞平静和有必要保留在体内的自我更新。 Cell Stem Cell. Mar, 2008 | Pubmed ID: 18371452 昼夜节律: 干细胞交通时间。 Nature. Mar, 2008 | Pubmed ID: 18368105 中性 Sphingomyelinase 基因 SMPD3 突变指证神经酰胺途径人类白血病。 Blood. May, 2008 | Pubmed ID: 18299447 基于干细胞的治疗的前景。 Cell. Feb, 2008 | Pubmed ID: 18295571 癌症干细胞样性质的人类子宫内膜肿瘤启动细胞的功能分析。 Cell Cycle (Georgetown, Tex.). Jan, 2008 | Pubmed ID: 18256549 药理针对体内的干/祖人口是增强的骨再生的小鼠与相关联。 The Journal of Clinical Investigation. Feb, 2008 | Pubmed ID: 18219387 解构干细胞自我更新: 细胞周期调控的遗传见解。 Nature Reviews. Genetics. Feb, 2008 | Pubmed ID: 18202695 剂量减少白消安、 环磷酰胺和自体造血干细胞移植治疗人类免疫缺陷病毒相关淋巴瘤: 艾滋病恶性肿瘤财团研究 020。 Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Jan, 2008 | Pubmed ID: 18158962 微分体内的潜力从人类脐带血和成人外周血内皮祖细胞形成功能长效船只。 Blood. Feb, 2008 | Pubmed ID: 17993613 造血干细胞龛的分析。 Current Protocols in Stem Cell Biology. Nov, 2007 | Pubmed ID: 18785177 在小鼠造血干细胞检测中的限制因素。 Cell Stem Cell. 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Scadden1 1Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Stem Cell Institute, 2Wellman Center for Photomedicine and Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School JoVE 51289 Medicine 归巢的骨髓造血细胞 Rushdia Z. Yusuf1, David T. Scadden1 1Center for Regenerative Medicine, MGH - Massachusetts General Hospital JoVE 1104 Biology
顺序 Dongsu Park1, Joel A. Spencer2, Charles P. Lin2, David T. Scadden1 1Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Stem Cell Institute, 2Wellman Center for Photomedicine and Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School JoVE 51289 Medicine
归巢的骨髓造血细胞 Rushdia Z. Yusuf1, David T. Scadden1 1Center for Regenerative Medicine, MGH - Massachusetts General Hospital JoVE 1104 Biology