David Botstein Calico Life Sciences LLC Biography Publications Institution JoVE Articles David Botstein has not added a biography. If you are David Botstein and would like to personalize this page please email our Author Liaison for assistance. Publications Analysis of Polygenic Mutants Suggests a Role for Mediator in Regulating Transcriptional Activation Distance in Saccharomyces Cerevisiae Genetics. Oct, 2015 | Pubmed ID: 26281848 Extrachromosomal Circular DNA is Common in Yeast Proceedings of the National Academy of Sciences of the United States of America. Jun, 2015 | Pubmed ID: 26038577 Characterizing the in Vivo Role of Trehalose in Saccharomyces Cerevisiae Using the AGT1 Transporter Proceedings of the National Academy of Sciences of the United States of America. May, 2015 | Pubmed ID: 25918382 Lasker∼Koshland to Genetics Pioneer Cell. Sep, 2014 | Pubmed ID: 25215481 Synthetic Biology Tools for Programming Gene Expression Without Nutritional Perturbations in Saccharomyces Cerevisiae Nucleic Acids Research. Apr, 2014 | Pubmed ID: 24445804 Yeast Metabolic and Signaling Genes Are Required for Heat-shock Survival and Have Little Overlap with the Heat-induced Genes Proceedings of the National Academy of Sciences of the United States of America. Nov, 2013 | Pubmed ID: 24167267 Pervasive Genetic Hitchhiking and Clonal Interference in Forty Evolving Yeast Populations Nature. Aug, 2013 | Pubmed ID: 23873039 A New System for Comparative Functional Genomics of Saccharomyces Yeasts Genetics. Sep, 2013 | Pubmed ID: 23852385 Phylogenetic Portrait of the Saccharomyces Cerevisiae Functional Genome G3 (Bethesda, Md.). Aug, 2013 | Pubmed ID: 23749449 Genetic Basis of Ammonium Toxicity Resistance in a Sake Strain of Yeast: A Mendelian Case G3 (Bethesda, Md.). Mar, 2013 | Pubmed ID: 23550140 Automating the Construction of Gene Ontologies Nature Biotechnology. Jan, 2013 | Pubmed ID: 23302932 Synthetic Gene Expression Perturbation Systems with Rapid, Tunable, Single-gene Specificity in Yeast Nucleic Acids Research. Feb, 2013 | Pubmed ID: 23275543 TOR and RAS Pathways Regulate Desiccation Tolerance in Saccharomyces Cerevisiae Molecular Biology of the Cell. Jan, 2013 | Pubmed ID: 23171550 Decoupling Nutrient Signaling from Growth Rate Causes Aerobic Glycolysis and Deregulation of Cell Size and Gene Expression Molecular Biology of the Cell. Jan, 2013 | Pubmed ID: 23135997 Why We Need More Basic Biology Research, Not Less Molecular Biology of the Cell. Nov, 2012 | Pubmed ID: 23112227 Loss of a 20S Proteasome Activator in Saccharomyces Cerevisiae Downregulates Genes Important for Genomic Integrity, Increases DNA Damage, and Selectively Sensitizes Cells to Agents with Diverse Mechanisms of Action G3 (Bethesda, Md.). Aug, 2012 | Pubmed ID: 22908043 Perturbation-based Analysis and Modeling of Combinatorial Regulation in the Yeast Sulfur Assimilation Pathway Molecular Biology of the Cell. Aug, 2012 | Pubmed ID: 22696683 Combinatorial Control of Diverse Metabolic and Physiological Functions by Transcriptional Regulators of the Yeast Sulfur Assimilation Pathway Molecular Biology of the Cell. Aug, 2012 | Pubmed ID: 22696679 A Conserved Cell Growth Cycle Can Account for the Environmental Stress Responses of Divergent Eukaryotes Molecular Biology of the Cell. May, 2012 | Pubmed ID: 22456505 Yeast: an Experimental Organism for 21st Century Biology Genetics. Nov, 2011 | Pubmed ID: 22084421 Metabolic Cycling Without Cell Division Cycling in Respiring Yeast Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011 | Pubmed ID: 22065748 A Test of the Coordinated Expression Hypothesis for the Origin and Maintenance of the GAL Cluster in Yeast PloS One. 2011 | Pubmed ID: 21966486 Fast-acting and Nearly Gratuitous Induction of Gene Expression and Protein Depletion in Saccharomyces Cerevisiae Molecular Biology of the Cell. Nov, 2011 | Pubmed ID: 21965290 Coordinated Regulation of Sulfur and Phospholipid Metabolism Reflects the Importance of Methylation in the Growth of Yeast Molecular Biology of the Cell. Nov, 2011 | Pubmed ID: 21900497 Survival of Starving Yeast is Correlated with Oxidative Stress Response and Nonrespiratory Mitochondrial Function Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011 | Pubmed ID: 21734149 Genetic Variation and the Fate of Beneficial Mutations in Asexual Populations Genetics. Jul, 2011 | Pubmed ID: 21546542 Coupling Among Growth Rate Response, Metabolic Cycle, and Cell Division Cycle in Yeast Molecular Biology of the Cell. Jun, 2011 | Pubmed ID: 21525243 Genome-sequencing Anniversary. Fruits of Genome Sequences for Biology Science (New York, N.Y.). Feb, 2011 | Pubmed ID: 21350164 System-level Analysis of Genes and Functions Affecting Survival During Nutrient Starvation in Saccharomyces Cerevisiae Genetics. Jan, 2011 | Pubmed ID: 20944018 Evaluating Gene Expression Dynamics Using Pairwise RNA FISH Data PLoS Computational Biology. 2010 | Pubmed ID: 21079668 Technological Innovation Leads to Fundamental Understanding in Cell Biology Molecular Biology of the Cell. Nov, 2010 | Pubmed ID: 21079013 Adaptation to Diverse Nitrogen-limited Environments by Deletion or Extrachromosomal Element Formation of the GAP1 Locus Proceedings of the National Academy of Sciences of the United States of America. Oct, 2010 | Pubmed ID: 20937885 Metabolic Cycling in Single Yeast Cells from Unsynchronized Steady-state Populations Limited on Glucose or Phosphate Proceedings of the National Academy of Sciences of the United States of America. Apr, 2010 | Pubmed ID: 20335538 Optimized Detection of Sequence Variation in Heterozygous Genomes Using DNA Microarrays with Isothermal-melting Probes Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010 | Pubmed ID: 20080586 It's the Data! Molecular Biology of the Cell. Jan, 2010 | Pubmed ID: 20048255 Saccharomyces Genome Database Provides Mutant Phenotype Data Nucleic Acids Research. Jan, 2010 | Pubmed ID: 19906697 Growth-limiting Intracellular Metabolites in Yeast Growing Under Diverse Nutrient Limitations Molecular Biology of the Cell. Jan, 2010 | Pubmed ID: 19889834 Recurated Protein Interaction Datasets Nature Methods. Dec, 2009 | Pubmed ID: 19935838 A Molecular Barcoded Yeast ORF Library Enables Mode-of-action Analysis of Bioactive Compounds Nature Biotechnology. Apr, 2009 | Pubmed ID: 19349972 The Cost of Gene Expression Underlies a Fitness Trade-off in Yeast Proceedings of the National Academy of Sciences of the United States of America. Apr, 2009 | Pubmed ID: 19299502 Predicting Cellular Growth from Gene Expression Signatures PLoS Computational Biology. Jan, 2009 | Pubmed ID: 19119411 Slow Growth Induces Heat-shock Resistance in Normal and Respiratory-deficient Yeast Molecular Biology of the Cell. Feb, 2009 | Pubmed ID: 19056679 The Repertoire and Dynamics of Evolutionary Adaptations to Controlled Nutrient-limited Environments in Yeast PLoS Genetics. Dec, 2008 | Pubmed ID: 19079573 Influence of Genotype and Nutrition on Survival and Metabolism of Starving Yeast Proceedings of the National Academy of Sciences of the United States of America. May, 2008 | Pubmed ID: 18456835 Comparing Whole Genomes Using DNA Microarrays Nature Reviews. Genetics. Apr, 2008 | Pubmed ID: 18347592 Gene Ontology Annotations at SGD: New Data Sources and Annotation Methods Nucleic Acids Research. Jan, 2008 | Pubmed ID: 17982175 Coordination of Growth Rate, Cell Cycle, Stress Response, and Metabolic Activity in Yeast Molecular Biology of the Cell. Jan, 2008 | Pubmed ID: 17959824 The Princeton Protein Orthology Database (P-POD): a Comparative Genomics Analysis Tool for Biologists PloS One. 2007 | Pubmed ID: 17712414 Orthology and Functional Conservation in Eukaryotes Annual Review of Genetics. 2007 | Pubmed ID: 17678444 Genome-wide Analysis of Nucleotide-level Variation in Commonly Used Saccharomyces Cerevisiae Strains PloS One. 2007 | Pubmed ID: 17389913 Expanded Protein Information at SGD: New Pages and Proteome Browser Nucleic Acids Research. Jan, 2007 | Pubmed ID: 17142221 Identification of Alterations in DNA Copy Number in Host Stromal Cells During Tumor Progression Proceedings of the National Academy of Sciences of the United States of America. Dec, 2006 | Pubmed ID: 17167050 Conservation of the Metabolomic Response to Starvation Across Two Divergent Microbes Proceedings of the National Academy of Sciences of the United States of America. Dec, 2006 | Pubmed ID: 17159141 Gene Expression Profiles Do Not Consistently Predict the Clinical Treatment Response in Locally Advanced Breast Cancer Molecular Cancer Therapeutics. Nov, 2006 | Pubmed ID: 17121939 Ammonium Toxicity and Potassium Limitation in Yeast PLoS Biology. Oct, 2006 | Pubmed ID: 17048990 Saccharomyces Cerevisiae S288C Genome Annotation: a Working Hypothesis Yeast (Chichester, England). Sep, 2006 | Pubmed ID: 17001629 Back to the Future: Education for Systems-level Biologists Nature Reviews. Molecular Cell Biology. Nov, 2006 | Pubmed ID: 16990789 Accumulation of Recessive Lethal Mutations in Saccharomyces Cerevisiae Mlh1 Mismatch Repair Mutants is Not Associated with Gross Chromosomal Rearrangements Genetics. Sep, 2006 | Pubmed ID: 16816424 Comprehensive Curation and Analysis of Global Interaction Networks in Saccharomyces Cerevisiae Journal of Biology. 2006 | Pubmed ID: 16762047 Willing to Do the Math: an Interview with David Botstein. Interview by Jane Gitschier PLoS Genetics. May, 2006 | Pubmed ID: 16733551 Genome-wide Detection of Polymorphisms at Nucleotide Resolution with a Single DNA Microarray Science (New York, N.Y.). Mar, 2006 | Pubmed ID: 16527929 Genome-scale Identification of Membrane-associated Human MRNAs PLoS Genetics. Jan, 2006 | Pubmed ID: 16415983 Genome Snapshot: a New Resource at the Saccharomyces Genome Database (SGD) Presenting an Overview of the Saccharomyces Cerevisiae Genome Nucleic Acids Research. Jan, 2006 | Pubmed ID: 16381907 Transcriptional Response of Steady-state Yeast Cultures to Transient Perturbations in Carbon Source Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006 | Pubmed ID: 16381818 Changing Perspectives in Yeast Research Nearly a Decade After the Genome Sequence Genome Research. Dec, 2005 | Pubmed ID: 16339358 Gene Expression Profiling Reveals Molecularly and Clinically Distinct Subtypes of Glioblastoma Multiforme Proceedings of the National Academy of Sciences of the United States of America. Apr, 2005 | Pubmed ID: 15827123 A DNA Microarray Survey of Gene Expression in Normal Human Tissues Genome Biology. 2005 | Pubmed ID: 15774023 Homeostatic Adjustment and Metabolic Remodeling in Glucose-limited Yeast Cultures Molecular Biology of the Cell. May, 2005 | Pubmed ID: 15758028 Inference of Combinatorial Regulation in Yeast Transcriptional Networks: a Case Study of Sporulation Proceedings of the National Academy of Sciences of the United States of America. Feb, 2005 | Pubmed ID: 15684073 Fungal BLAST and Model Organism BLASTP Best Hits: New Comparison Resources at the Saccharomyces Genome Database (SGD) Nucleic Acids Research. Jan, 2005 | Pubmed ID: 15608219 GeneXplorer: an Interactive Web Application for Microarray Data Visualization and Analysis BMC Bioinformatics. Oct, 2004 | Pubmed ID: 15458579 Disruption of Yeast Forkhead-associated Cell Cycle Transcription by Oxidative Stress Molecular Biology of the Cell. Dec, 2004 | Pubmed ID: 15371544 A Method for Detecting and Correcting Feature Misidentification on Expression Microarrays BMC Genomics. Sep, 2004 | Pubmed ID: 15357875 GO::TermFinder--open Source Software for Accessing Gene Ontology Information and Finding Significantly Enriched Gene Ontology Terms Associated with a List of Genes Bioinformatics (Oxford, England). Dec, 2004 | Pubmed ID: 15297299 Nutritional Homeostasis in Batch and Steady-state Culture of Yeast Molecular Biology of the Cell. Sep, 2004 | Pubmed ID: 15240820 Saccharomyces Genome Database: Underlying Principles and Organisation Briefings in Bioinformatics. Mar, 2004 | Pubmed ID: 15153302 Prediction of Survival in Diffuse Large-B-cell Lymphoma Based on the Expression of Six Genes The New England Journal of Medicine. Apr, 2004 | Pubmed ID: 15115829 Universal Reference RNA As a Standard for Microarray Experiments BMC Genomics. Mar, 2004 | Pubmed ID: 15113400 Different Gene Expression Patterns in Invasive Lobular and Ductal Carcinomas of the Breast Molecular Biology of the Cell. Jun, 2004 | Pubmed ID: 15034139 Ira Herskowitz: 1946-2003 Genetics. Feb, 2004 | Pubmed ID: 15020456 Diverse and Specific Gene Expression Responses to Stresses in Cultured Human Cells Molecular Biology of the Cell. May, 2004 | Pubmed ID: 15004229 Introductory Science and Mathematics Education for 21st-Century Biologists Science (New York, N.Y.). Feb, 2004 | Pubmed ID: 14764865 Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities Between Tumors and Wounds PLoS Biology. Feb, 2004 | Pubmed ID: 14737219 Gene Expression Profiling Identifies Clinically Relevant Subtypes of Prostate Cancer Proceedings of the National Academy of Sciences of the United States of America. Jan, 2004 | Pubmed ID: 14711987 Saccharomyces Genome Database (SGD) Provides Tools to Identify and Analyze Sequences from Saccharomyces Cerevisiae and Related Sequences from Other Organisms Nucleic Acids Research. Jan, 2004 | Pubmed ID: 14681421 Transcriptional Remodeling in Response to Iron Deprivation in Saccharomyces Cerevisiae Molecular Biology of the Cell. Mar, 2004 | Pubmed ID: 14668481 The Role of Heat Shock Transcription Factor 1 in the Genome-wide Regulation of the Mammalian Heat Shock Response Molecular Biology of the Cell. Mar, 2004 | Pubmed ID: 14668476 Diverse Effects of Methylseleninic Acid on the Transcriptional Program of Human Prostate Cancer Cells Molecular Biology of the Cell. Feb, 2004 | Pubmed ID: 14617803 Gene Expression Patterns and Gene Copy Number Changes in Dermatofibrosarcoma Protuberans The American Journal of Pathology. Dec, 2003 | Pubmed ID: 14633610 T Cell Receptor-independent Basal Signaling Via Erk and Abl Kinases Suppresses RAG Gene Expression PLoS Biology. Nov, 2003 | Pubmed ID: 14624253 Bmi-1 Regulation of INK4A-ARF is a Downstream Requirement for Transformation of Hematopoietic Progenitors by E2a-Pbx1 Molecular Cell. Aug, 2003 | Pubmed ID: 14536079 Systemic and Cell Type-specific Gene Expression Patterns in Scleroderma Skin Proceedings of the National Academy of Sciences of the United States of America. Oct, 2003 | Pubmed ID: 14530402 Tissue Microarray Validation of Epidermal Growth Factor Receptor and SALL2 in Synovial Sarcoma with Comparison to Tumors of Similar Histology The American Journal of Pathology. Oct, 2003 | Pubmed ID: 14507652 Endothelial Cell Diversity Revealed by Global Expression Profiling Proceedings of the National Academy of Sciences of the United States of America. Sep, 2003 | Pubmed ID: 12963823 Gene Expression Patterns in Ovarian Carcinomas Molecular Biology of the Cell. Nov, 2003 | Pubmed ID: 12960427 Variation in Gene Expression Patterns in Human Gastric Cancers Molecular Biology of the Cell. Aug, 2003 | Pubmed ID: 12925757 Repeated Observation of Breast Tumor Subtypes in Independent Gene Expression Data Sets Proceedings of the National Academy of Sciences of the United States of America. Jul, 2003 | Pubmed ID: 12829800 A Bayesian Framework for Combining Heterogeneous Data Sources for Gene Function Prediction (in Saccharomyces Cerevisiae) Proceedings of the National Academy of Sciences of the United States of America. Jul, 2003 | Pubmed ID: 12826619 Module Networks: Identifying Regulatory Modules and Their Condition-specific Regulators from Gene Expression Data Nature Genetics. Jun, 2003 | Pubmed ID: 12740579 Generalized Singular Value Decomposition for Comparative Analysis of Genome-scale Expression Data Sets of Two Different Organisms Proceedings of the National Academy of Sciences of the United States of America. Mar, 2003 | Pubmed ID: 12631705 Planning the Genome Institute's Future Science (New York, N.Y.). Mar, 2003 | Pubmed ID: 12624247 Discovering Genotypes Underlying Human Phenotypes: Past Successes for Mendelian Disease, Future Approaches for Complex Disease Nature Genetics. Mar, 2003 | Pubmed ID: 12610532 Variation in Gene Expression Patterns in Follicular Lymphoma and the Response to Rituximab Proceedings of the National Academy of Sciences of the United States of America. Feb, 2003 | Pubmed ID: 12571354 A Genome Scan for Hypertension Susceptibility Loci in Populations of Chinese and Japanese Origins American Journal of Hypertension. Feb, 2003 | Pubmed ID: 12559686 SOURCE: a Unified Genomic Resource of Functional Annotations, Ontologies, and Gene Expression Data Nucleic Acids Research. Jan, 2003 | Pubmed ID: 12519986 Saccharomyces Genome Database (SGD) Provides Biochemical and Structural Information for Budding Yeast Proteins Nucleic Acids Research. Jan, 2003 | Pubmed ID: 12519985 The Stanford Microarray Database: Data Access and Quality Assessment Tools Nucleic Acids Research. Jan, 2003 | Pubmed ID: 12519956 Expression Array Technology in the Diagnosis and Treatment of Breast Cancer Molecular Interventions. Apr, 2002 | Pubmed ID: 14993355 A Systematic Approach to Reconstructing Transcription Networks in Saccharomycescerevisiae Proceedings of the National Academy of Sciences of the United States of America. Dec, 2002 | Pubmed ID: 12482955 Overview of the Alliance for Cellular Signaling Nature. Dec, 2002 | Pubmed ID: 12478301 Expression of Cytokeratins 17 and 5 Identifies a Group of Breast Carcinomas with Poor Clinical Outcome The American Journal of Pathology. Dec, 2002 | Pubmed ID: 12466114 Phospholipase A2 Group IIA Expression in Gastric Adenocarcinoma is Associated with Prolonged Survival and Less Frequent Metastasis Proceedings of the National Academy of Sciences of the United States of America. Dec, 2002 | Pubmed ID: 12456890 Characteristic Genome Rearrangements in Experimental Evolution of Saccharomyces Cerevisiae Proceedings of the National Academy of Sciences of the United States of America. Dec, 2002 | Pubmed ID: 12446845 Nonparametric Methods for Identifying Differentially Expressed Genes in Microarray Data Bioinformatics (Oxford, England). Nov, 2002 | Pubmed ID: 12424116 Diversity, Topographic Differentiation, and Positional Memory in Human Fibroblasts Proceedings of the National Academy of Sciences of the United States of America. Oct, 2002 | Pubmed ID: 12297622 Microarray Analysis Reveals a Major Direct Role of DNA Copy Number Alteration in the Transcriptional Program of Human Breast Tumors Proceedings of the National Academy of Sciences of the United States of America. Oct, 2002 | Pubmed ID: 12297621 Misfolded Proteins Are Competent to Mediate a Subset of the Responses to Heat Shock in Saccharomyces Cerevisiae The Journal of Biological Chemistry. Nov, 2002 | Pubmed ID: 12239211 Genomic Expression Programs and the Integration of the CD28 Costimulatory Signal in T Cell Activation Proceedings of the National Academy of Sciences of the United States of America. Sep, 2002 | Pubmed ID: 12195013 Transcriptional Response of Human Mast Cells Stimulated Via the Fc(epsilon)RI and Identification of Mast Cells As a Source of IL-11 BMC Immunology. Jun, 2002 | Pubmed ID: 12079505 Transformation of Follicular Lymphoma to Diffuse Large-cell Lymphoma: Alternative Patterns with Increased or Decreased Expression of C-myc and Its Regulated Genes Proceedings of the National Academy of Sciences of the United States of America. Jun, 2002 | Pubmed ID: 12077300 Immunoelectron Microscopy of Aldehyde-fixed Yeast Cells Methods in Enzymology. 2002 | Pubmed ID: 12073367 Saccharomyces Genome Database Methods in Enzymology. 2002 | Pubmed ID: 12073322 Challenges in Developing a Molecular Characterization of Cancer Seminars in Oncology. Jun, 2002 | Pubmed ID: 12063681 Identification of Genes Periodically Expressed in the Human Cell Cycle and Their Expression in Tumors Molecular Biology of the Cell. Jun, 2002 | Pubmed ID: 12058064 Gene Expression Patterns in Human Liver Cancers Molecular Biology of the Cell. Jun, 2002 | Pubmed ID: 12058060 Genome-wide Analysis of Gene Expression Regulated by the Calcineurin/Crz1p Signaling Pathway in Saccharomyces Cerevisiae The Journal of Biological Chemistry. Aug, 2002 | Pubmed ID: 12058033 Systematic Structure-function Analysis of the Small GTPase Arf1 in Yeast Molecular Biology of the Cell. May, 2002 | Pubmed ID: 12006660 Molecular Characterisation of Soft Tissue Tumours: a Gene Expression Study Lancet. Apr, 2002 | Pubmed ID: 11965276 A Polymorphism in the Beta1 Adrenergic Receptor is Associated with Resting Heart Rate American Journal of Human Genetics. Apr, 2002 | Pubmed ID: 11854867 Stereotyped and Specific Gene Expression Programs in Human Innate Immune Responses to Bacteria Proceedings of the National Academy of Sciences of the United States of America. Jan, 2002 | Pubmed ID: 11805339 Saccharomyces Genome Database (SGD) Provides Secondary Gene Annotation Using the Gene Ontology (GO) Nucleic Acids Research. Jan, 2002 | Pubmed ID: 11752257 कोशिकाओं से Extrachromosomal परिपत्र डीएनए के जीनोम चौड़ा शोधन Henrik D. Møller1, Rasmus K. Bojsen2, Chris Tachibana3, Lance Parsons4, David Botstein5, Birgitte Regenberg1 1Department of Biology, University of Copenhagen, 2National Veterinary Institute, Technical University of Denmark, 3Group Health Research Institute, 4Lewis-Sigler Institute for Integrative Genomics, Princeton University, 5Calico Life Sciences LLC Biology रैपिड संश्लेषण और GFP आधारित पत्रकारों के साथ रासायनिक सक्रिय प्रतिलेखन कारक की स्क्रीनिंग R. Scott McIsaac*1,3, Benjamin L. Oakes*1, David Botstein1,2, Marcus B. Noyes1 1The Lewis-Sigler Institute for Integrative Genomics, Princeton University, 2Department of Molecular Biology, Princeton University, 3Division of Chemistry and Chemical Engineering, California Institute of Technology JoVE 51153 Biology प्रतिदीप्ति का प्रयोग mRNA अणुओं के दृश्य और विश्लेषण R. Scott McIsaac1,2, Sanford J. Silverman1, Lance Parsons1, Ping Xu1, Ryan Briehof1, Megan N. McClean1, David Botstein1,3 1The Lewis-Sigler Institute for Integrative Genomics, Princeton University, 2Graduate Program in Quantitative and Computational Biology, Princeton University, 3Department of Molecular Biology, Princeton University JoVE 50382 Biology
कोशिकाओं से Extrachromosomal परिपत्र डीएनए के जीनोम चौड़ा शोधन Henrik D. Møller1, Rasmus K. Bojsen2, Chris Tachibana3, Lance Parsons4, David Botstein5, Birgitte Regenberg1 1Department of Biology, University of Copenhagen, 2National Veterinary Institute, Technical University of Denmark, 3Group Health Research Institute, 4Lewis-Sigler Institute for Integrative Genomics, Princeton University, 5Calico Life Sciences LLC Biology
रैपिड संश्लेषण और GFP आधारित पत्रकारों के साथ रासायनिक सक्रिय प्रतिलेखन कारक की स्क्रीनिंग R. Scott McIsaac*1,3, Benjamin L. Oakes*1, David Botstein1,2, Marcus B. Noyes1 1The Lewis-Sigler Institute for Integrative Genomics, Princeton University, 2Department of Molecular Biology, Princeton University, 3Division of Chemistry and Chemical Engineering, California Institute of Technology JoVE 51153 Biology
प्रतिदीप्ति का प्रयोग mRNA अणुओं के दृश्य और विश्लेषण R. Scott McIsaac1,2, Sanford J. Silverman1, Lance Parsons1, Ping Xu1, Ryan Briehof1, Megan N. McClean1, David Botstein1,3 1The Lewis-Sigler Institute for Integrative Genomics, Princeton University, 2Graduate Program in Quantitative and Computational Biology, Princeton University, 3Department of Molecular Biology, Princeton University JoVE 50382 Biology
