Dean A. Lee Center for Childhood Cancer and Blood Disease Nationwide Children's Hospital Biography Publications Institution JoVE Articles Dean A. Lee has not added a biography. If you are Dean A. Lee and would like to personalize this page please email our Author Liaison for assistance. Publications Aggressive Natural Killer-cell Leukemia mutational Landscape and Drug Profiling Highlight JAK-STAT Signaling As Therapeutic Target Nature Communications. Apr, 2018 | Pubmed ID: 29674644 Inhibiting TGF-beta Signaling Preserves the Function of Highly Activated, in Vitro Expanded Natural Killer Cells in AML and Colon Cancer Models PloS One. 2018 | Pubmed ID: 29342200 Ex Vivo-expanded NK Cells from Blood and Ascites of Ovarian Cancer Patients Are Cytotoxic Against Autologous Primary Ovarian Cancer Cells Cancer Immunology, Immunotherapy : CII. Apr, 2018 | Pubmed ID: 29299659 Ex Vivo-expanded Natural Killer Cells Derived From Long-term Cryopreserved Cord Blood Are Cytotoxic Against Primary Breast Cancer Cells Journal of Immunotherapy (Hagerstown, Md. : 1997). Feb/Mar, 2018 | Pubmed ID: 29189387 Venous Thromboembolism in Pediatric Hematopoietic Cell Transplant: A Multicenter Cohort Study Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Feb, 2018 | Pubmed ID: 29128552 Radiotherapy Enhances Natural Killer Cell Cytotoxicity and Localization in Pre-clinical Canine Sarcomas and First-in-dog Clinical Trial Journal for Immunotherapy of Cancer. Dec, 2017 | Pubmed ID: 29254507 Phase 1 Clinical Trial Using MbIL21 Ex Vivo-expanded Donor-derived NK Cells After Haploidentical Transplantation Blood. 10, 2017 | Pubmed ID: 28835441 Ex Vivo Expanded Natural Killer Cells from Breast Cancer Patients and Healthy Donors Are Highly Cytotoxic Against Breast Cancer Cell Lines and Patient-derived Tumours Breast Cancer Research : BCR. Jul, 2017 | Pubmed ID: 28668076 IL-18/IL-15/IL-12 Synergy Induces Elevated and Prolonged IFN-γ Production by Ex Vivo Expanded NK Cells Which is Not Due to Enhanced STAT4 Activation Molecular Immunology. Aug, 2017 | Pubmed ID: 28644973 Interferon Gamma Induces Changes in Natural Killer (NK) Cell Ligand Expression and Alters NK Cell-Mediated Lysis of Pediatric Cancer Cell Lines Frontiers in Immunology. 2017 | Pubmed ID: 28428785 The Histone Deacetylase Inhibitor Valproic Acid Inhibits NKG2D Expression in Natural Killer Cells Through Suppression of STAT3 and HDAC3 Scientific Reports. Mar, 2017 | Pubmed ID: 28338101 Natural Killer Cells in Malignant Hematology: A Primer for the Non-immunologist Blood Reviews. Mar, 2017 | Pubmed ID: 27665023 NK 세포 치료: 조 혈 줄기 세포 이식 후 질병 재발을 대상으로 합니다 Immunotherapy. Feb, 2012 | Pubmed ID: 22329587 막 바인딩된 IL 21 인간의 자연 킬러 세포의 지속적인된 Ex Vivo 확산을 촉진합니다 PloS One. 2012 | Pubmed ID: 22279576 고급 B 림프 악성 종양에 대 한 헌 조 혈 줄기 세포 이식 환자에서 질병 관리를 증가 시키기 위해 CD19 감독 T 세포를 일으키는 Human Gene Therapy. Jan, 2012 | Pubmed ID: 22107246 IL 21 신호 CD19 특정 T 셀 프로그래밍 B 혈통 악성 종양의 입양 Immunotherapy 향상 시킬 수 있습니다 Cancer Research. May, 2011 | Pubmed ID: 21558388 수집, 준비, 그리고 입양 Immunotherapy에 대 한 인간의 NK 세포의 기능 평가 Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20686960 인간 T 세포의 특이성을 리디렉션할 Chimeric 항 원 수용 체를 소개 하는 높은 처리량 Microelectroporation 장치 Biomedical Microdevices. Oct, 2010 | Pubmed ID: 20574820 CD19 리디렉션 및 Alloanergization에 결합 하 여 B-세포 악성 종양의 Allogeneic 세포 치료에 대 한 종양 관련 인간 T 세포를 생성 합니다 Cancer Research. May, 2010 | Pubmed ID: 20424114 PiggyBac Transposon/transposase 시스템 B 혈통 악성 종양 치료를 위한 CD19 특정 T 세포 생성 Human Gene Therapy. Apr, 2010 | Pubmed ID: 19905893 EBV + Lymphoproliferative 질병 내 화 LCH는 장기간된 화학요법 다음 Pediatric Blood & Cancer. Mar, 2008 | Pubmed ID: 17243127 MLL의 복잡 한 식에서 발생 하는 Cugbp1의 중단에 의해 C/EBPbeta 억제 Cancer Genetics and Cytogenetics. Sep, 2007 | Pubmed ID: 17854664 로 타 바이러스 백신입니다 The New England Journal of Medicine. Apr, 2006 | Pubmed ID: 16625014 Granulocytic 육 종 T(8;21) 급성 골수성 백혈병을 가진 아이에 폐 렴으로 제시: 형광 성 제자리 교 잡 하 여 진단 합니다 Journal of Pediatric Hematology/oncology. Jul, 2004 | Pubmed ID: 15218417 종양 관련 인간 CD4 + 규제 T 세포 및 그들의 Ligands: Immunotherapy에 대 한 의미 Immunity. Jan, 2004 | Pubmed ID: 14738769 활성화 된 주변 T 세포 Apoptosis를 Monocytes HLA 클래스 II 결 찰에 의해 활성화와 함께 교양 때 받 다 Cellular Immunology. Oct, 2003 | Pubmed ID: 14698144 Cas9 Ribonucleoproteins를 사용 하 여 노크 아웃 기본 및 확장 된 인간 NK 세포의 생성 Meisam Naeimi Kararoudi1, Hamid Dolatshad2, Prashant Trikha1, Syed-Rehan A. Hussain3, Ezgi Elmas1, Jennifer A. Foltz1, Jena E. Moseman1, Aarohi Thakkar1, Robin J. Nakkula1, Margaret Lamb1, Nitin Chakravarti1, K. John McLaughlin3, Dean A. Lee1 1Center for Childhood Cancer and Blood Disease, Nationwide Children's Hospital, 2Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, 3Center for Clinical and Translational Research, Nationwide Children's Hospital Research Institute JoVE 58237 Immunology and Infection 확장, 정화, 그리고 사람 말초혈 NK 세포 기능 평가 Srinivas S. Somanchi1, Vladimir V. Senyukov1, Cecele J. Denman1, Dean A. Lee1 1Division of Pediatrics, MD Anderson Cancer Center - University of Texas JoVE 2540 Immunology and Infection
Cas9 Ribonucleoproteins를 사용 하 여 노크 아웃 기본 및 확장 된 인간 NK 세포의 생성 Meisam Naeimi Kararoudi1, Hamid Dolatshad2, Prashant Trikha1, Syed-Rehan A. Hussain3, Ezgi Elmas1, Jennifer A. Foltz1, Jena E. Moseman1, Aarohi Thakkar1, Robin J. Nakkula1, Margaret Lamb1, Nitin Chakravarti1, K. John McLaughlin3, Dean A. Lee1 1Center for Childhood Cancer and Blood Disease, Nationwide Children's Hospital, 2Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, 3Center for Clinical and Translational Research, Nationwide Children's Hospital Research Institute JoVE 58237 Immunology and Infection
확장, 정화, 그리고 사람 말초혈 NK 세포 기능 평가 Srinivas S. Somanchi1, Vladimir V. Senyukov1, Cecele J. Denman1, Dean A. Lee1 1Division of Pediatrics, MD Anderson Cancer Center - University of Texas JoVE 2540 Immunology and Infection