Dmitry Lyumkis Biography Publications JoVE Articles Dmitry Lyumkis has not added a biography. If you are Dmitry Lyumkis and would like to personalize this page please email our Author Liaison for assistance. Publications Multivalent Interactions Essential for Lentiviral Integrase Function Nature Communications. 05, 2022 | Pubmed ID: 35504909 Pretransition State and Apo Structures of the Filament-forming Enzyme SgrAI Elucidate Mechanisms of Activation and Substrate Specificity The Journal of Biological Chemistry. 04, 2022 | Pubmed ID: 35202658 Quantitative Mining of Compositional Heterogeneity in Cryo-EM Datasets of Ribosome Assembly Intermediates Structure (London, England : 1993). 04, 2022 | Pubmed ID: 34990602 Retroviral Integrase: Structure, Mechanism, and Inhibition The Enzymes. 2021 | Pubmed ID: 34861940 HIV-1 Integrase Inhibitors with Modifications That Affect Their Potencies Against Drug Resistant Integrase Mutants ACS Infectious Diseases. 06, 2021 | Pubmed ID: 33686850 Integrase Strand Transfer Inhibitors Are Effective Anti-HIV Drugs Viruses. 01, 2021 | Pubmed ID: 33572956 Evaluating Local and Directional Resolution of Cryo-EM Density Maps Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 33368004 Tools for Visualizing and Analyzing Fourier Space Sampling in Cryo-EM Progress in Biophysics and Molecular Biology. 03, 2021 | Pubmed ID: 32645314 Molecular Determinants for DsDNA Translocation by the Transcription-repair Coupling and Evolvability Factor Mfd Nature Communications. 07, 2020 | Pubmed ID: 32719356 Structural Biology of HIV Integrase Strand Transfer Inhibitors Trends in Pharmacological Sciences. 09, 2020 | Pubmed ID: 32624197 HIV-1 Integrase Inhibitors That Are Active Against Drug-Resistant Integrase Mutants Antimicrobial Agents and Chemotherapy. 08, 2020 | Pubmed ID: 32601157 Structural Basis for Strand-transfer Inhibitor Binding to HIV Intasomes Science (New York, N.Y.). 02, 2020 | Pubmed ID: 32001521 SrmB Rescues Trapped Ribosome Assembly Intermediates Journal of Molecular Biology. 02, 2020 | Pubmed ID: 31877323 Non-uniformity of Projection Distributions Attenuates Resolution in Cryo-EM Progress in Biophysics and Molecular Biology. 01, 2020 | Pubmed ID: 31525386 Mechanism of Filamentation-Induced Allosteric Activation of the SgrAI Endonuclease Structure (London, England : 1993). 10, 2019 | Pubmed ID: 31447289 Cryo-EM Structures of a Group II Intron Reverse Splicing into DNA Cell. 07, 2019 | Pubmed ID: 31348888 HIV-1 Integrase Tetramers Are the Antiviral Target of Pyridine-based Allosteric Integrase Inhibitors ELife. 05, 2019 | Pubmed ID: 31120420 Challenges and Opportunities in Cryo-EM Single-particle Analysis The Journal of Biological Chemistry. 03, 2019 | Pubmed ID: 30804214 Analysis of Discrete Local Variability and Structural Covariance in Macromolecular Assemblies Using Cryo-EM and Focused Classification Ultramicroscopy. 08, 2019 | Pubmed ID: 30528101 Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d Cell. 09, 2018 | Pubmed ID: 30241607 Sub-2 Å Ewald Curvature Corrected Structure of an AAV2 Capsid Variant Nature Communications. 09, 2018 | Pubmed ID: 30194371 Open and Closed Structures Reveal Allostery and Pliability in the HIV-1 Envelope Spike Nature. 07, 2017 | Pubmed ID: 28700571 Addressing Preferred Specimen Orientation in Single-particle Cryo-EM Through Tilting Nature Methods. Aug, 2017 | Pubmed ID: 28671674 Cryo-EM Structures and Atomic Model of the HIV-1 Strand Transfer Complex Intasome Science (New York, N.Y.). 01, 2017 | Pubmed ID: 28059769 Modular Assembly of the Bacterial Large Ribosomal Subunit Cell. Dec, 2016 | Pubmed ID: 27912064 Structural Basis for the Activation of IKK1/α Cell Reports. 11, 2016 | Pubmed ID: 27851956 Cryo-EM Reveals a Novel Octameric Integrase Structure for Betaretroviral Intasome Function Nature. Feb, 2016 | Pubmed ID: 26887496 Single-particle CryoEM Analysis at Near-atomic Resolution from Several Thousand Asymmetric Subunits Journal of Structural Biology. Nov, 2015 | Pubmed ID: 26470814 Model Building and Refinement of a Natively Glycosylated HIV-1 Env Protein by High-Resolution Cryoelectron Microscopy Structure (London, England : 1993). Oct, 2015 | Pubmed ID: 26388028
