Donald J. Buchsbaum

Publications

• S100A4 Promotes Pancreatic Cancer Progression Through a Dual Signaling Pathway Mediated by Src and Focal Adhesion Kinase
  Scientific Reports. 2015  |   Pubmed ID: 25677816
• Ovarian Cancer Stem Cells: Can Targeted Therapy Lead to Improved Progression-free Survival?
  World Journal of Stem Cells. Sep, 2014  |   Pubmed ID: 25258665
• Combination Therapy with Anti-DR5 Antibody and Tamoxifen for Triple Negative Breast Cancer
  Cancer Biology & Therapy. Aug, 2014  |   Pubmed ID: 25084100
• Pazopanib Combined with Radiation: in Vivo Model of Interaction
  Cancer Biotherapy & Radiopharmaceuticals. Aug, 2014  |   Pubmed ID: 24945464
• Recurrent Read-through Fusion Transcripts in Breast Cancer
  Breast Cancer Research and Treatment. Jul, 2014  |   Pubmed ID: 24929677
• Inhibition of Wnt/β-catenin Pathway by Niclosamide: a Therapeutic Target for Ovarian Cancer
  Gynecologic Oncology. Jul, 2014  |   Pubmed ID: 24736023
• Multi-targeted Therapy of Cancer by Niclosamide: A New Application for an Old Drug
  Cancer Letters. Jul, 2014  |   Pubmed ID: 24732808
• Effect of Niclosamide on Basal-like Breast Cancers
  Molecular Cancer Therapeutics. Apr, 2014  |   Pubmed ID: 24552774
• Will Detection of MicroRNA Biomarkers in Blood Improve the Diagnosis and Survival of Patients with Pancreatic Cancer?
  JAMA. Jan 22-29, 2014  |   Pubmed ID: 24449314
• Monoclonal Antibody-based Immunotherapy of Ovarian Cancer: Targeting Ovarian Cancer Cells with the B7-H3-specific MAb 376.96
  Gynecologic Oncology. Jan, 2014  |   Pubmed ID: 24216048
• Antagonistic Effects of Anti-EMMPRIN Antibody when Combined with Chemotherapy Against Hypovascular Pancreatic Cancers
  Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Feb, 2014  |   Pubmed ID: 23836505
• The Wnt/β-catenin Pathway in Ovarian Cancer: a Review
  Gynecologic Oncology. Dec, 2013  |   Pubmed ID: 24125749
• Catalase Abrogates β-lapachone-induced PARP1 Hyperactivation-directed Programmed Necrosis in NQO1-positive Breast Cancers
  Molecular Cancer Therapeutics. Oct, 2013  |   Pubmed ID: 23883585
• Lung Resistance-related Protein (LRP) Expression in Malignant Ascitic Cells As a Prognostic Marker for Advanced Ovarian Serous Carcinoma
  Annals of Surgical Oncology. Sep, 2013  |   Pubmed ID: 23525731
• The C-terminal Region Mesd Peptide Mimics Full-length Mesd and Acts As an Inhibitor of Wnt/β-catenin Signaling in Cancer Cells
  PloS One. 2013  |   Pubmed ID: 23469146
• ST6Gal-I Protein Expression is Upregulated in Human Epithelial Tumors and Correlates with Stem Cell Markers in Normal Tissues and Colon Cancer Cell Lines
  Cancer Research. Apr, 2013  |   Pubmed ID: 23358684
• Chapter Seven--Cancer Treatment with Gene Therapy and Radiation Therapy
  Advances in Cancer Research. 2012  |   Pubmed ID: 23021246
• A Review of B7-H3 and B7-H4 Immune Molecules and Their Role in Ovarian Cancer
  Gynecologic Oncology. Nov, 2012  |   Pubmed ID: 22910694
• A Deimmunized Bispecific Ligand-directed Toxin That Shows an Impressive Anti-pancreatic Cancer Effect in a Systemic Nude Mouse Orthotopic Model
  Pancreas. Jul, 2012  |   Pubmed ID: 22258068
• Progress in Cancer Therapy
  Cancer Biotherapy & Radiopharmaceuticals. Feb, 2012  |   Pubmed ID: 22233333
• The Impact of Novel Retinoids in Combination with Platinum Chemotherapy on Ovarian Cancer Stem Cells
  Gynecologic Oncology. Apr, 2012  |   Pubmed ID: 22155260
• The Use of Retinoids in Ovarian Cancer: a Review of the Literature
  International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. Feb, 2012  |   Pubmed ID: 22146768
• Basal-like Breast Cancer Stem Cells Are Sensitive to Anti-DR5 Mediated Cytotoxicity
  Breast Cancer Research and Treatment. Jun, 2012  |   Pubmed ID: 21915634
• Cellular Model of Warburg Effect Identifies Tumor Promoting Function of UCP2 in Breast Cancer and Its Suppression by Genipin
  PloS One. 2011  |   Pubmed ID: 21935467
• Relationship Between Galectin-3 Expression and TRAIL Sensitivity in Breast Cancer
  Expert Review of Anticancer Therapy. Aug, 2011  |   Pubmed ID: 21916572
• Effect of Anti-DR5 and Chemotherapy on Basal-like Breast Cancer
  Breast Cancer Research and Treatment. Sep, 2011  |   Pubmed ID: 21901385
• Treatment of Small Cell Lung Cancer with TRA-8 in Combination with Cisplatin and Radiation
  Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Oct, 2011  |   Pubmed ID: 21722984
• Thrombospondin-1 Opens the Paracellular Pathway in Pulmonary Microvascular Endothelia Through EGFR/ErbB2 Activation
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2011  |   Pubmed ID: 21531776
• Early Therapy Evaluation of Combined Cetuximab and Irinotecan in Orthotopic Pancreatic Tumor Xenografts by Dynamic Contrast-enhanced Magnetic Resonance Imaging
  Molecular Imaging. Jun, 2011  |   Pubmed ID: 21496446
• Mechanisms of Drug Sensitization to TRA-8, an Agonistic Death Receptor 5 Antibody, Involve Modulation of the Intrinsic Apoptotic Pathway in Human Breast Cancer Cells
  Molecular Cancer Research : MCR. Apr, 2011  |   Pubmed ID: 21357440
• Combined Modality Therapy with TRAIL or Agonistic Death Receptor Antibodies
  Cancer Biology & Therapy. Mar, 2011  |   Pubmed ID: 21263219
• Anti-tumor Activity of an Anti-DR5 Monoclonal Antibody, TRA-8, in Combination with Taxane/platinum-based Chemotherapy in an Ovarian Cancer Model
  Gynecologic Oncology. Apr, 2011  |   Pubmed ID: 21211830
• DCE-MRI Detects Early Vascular Response in Breast Tumor Xenografts Following Anti-DR5 Therapy
  Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Feb, 2011  |   Pubmed ID: 20383593
• KISS1 Over-expression Suppresses Metastasis of Pancreatic Adenocarcinoma in a Xenograft Mouse Model
  Clinical & Experimental Metastasis. Dec, 2010  |   Pubmed ID: 20844932
• Overcoming TRAIL Resistance in Ovarian Carcinoma
  Gynecologic Oncology. Oct, 2010  |   Pubmed ID: 20638107
• A New Drug Delivery Method of Bispecific Ligand-directed Toxins, Which Reduces Toxicity and Promotes Efficacy in a Model of Orthotopic Pancreatic Cancer
  Pancreas. Aug, 2010  |   Pubmed ID: 20182395
• Monoclonal Antibodies in the Treatment of Pancreatic Cancer
  Immunotherapy. Mar, 2009  |   Pubmed ID: 20046965
• Experimental Cancer Therapy Using Restoration of NAD+ -linked 15-hydroxyprostaglandin Dehydrogenase Expression
  Molecular Cancer Therapeutics. Nov, 2009  |   Pubmed ID: 19887544
• Effect of TRA-8 Anti-death Receptor 5 Antibody in Combination with Chemotherapy in an Ex Vivo Human Ovarian Cancer Model
  International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. Jul, 2009  |   Pubmed ID: 19574765
• Anti-EMMPRIN Monoclonal Antibody As a Novel Agent for Therapy of Head and Neck Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2009  |   Pubmed ID: 19509148
• Polyethylene Glycosylated Curcumin Conjugate Inhibits Pancreatic Cancer Cell Growth Through Inactivation of Jab1
  Molecular Pharmacology. Jul, 2009  |   Pubmed ID: 19395473
• Preclinical Studies and Clinical Utilization of Monoclonal Antibodies in Epithelial Ovarian Cancer
  Gynecologic Oncology. Jun, 2009  |   Pubmed ID: 19232697
• In Vivo Efficacy of Marimastat and Chemoradiation in Head and Neck Cancer Xenografts
  ORL; Journal for Oto-rhino-laryngology and Its Related Specialties. 2009  |   Pubmed ID: 18931526
• Early Therapy Evaluation of Combined Anti-death Receptor 5 Antibody and Gemcitabine in Orthotopic Pancreatic Tumor Xenografts by Diffusion-weighted Magnetic Resonance Imaging
  Cancer Research. Oct, 2008  |   Pubmed ID: 18922909
• Molecular Chemotherapy of Pancreatic Cancer Using Novel Mutant Bacterial Cytosine Deaminase Gene
  Molecular Cancer Therapeutics. Sep, 2008  |   Pubmed ID: 18790765
• Molecular Targeted Therapies for Pancreatic Cancer
  American Journal of Surgery. Sep, 2008  |   Pubmed ID: 18718222
• Combination of Treatment with Death Receptor 5-specific Antibody with Therapeutic HPV DNA Vaccination Generates Enhanced Therapeutic Anti-tumor Effects
  Vaccine. Aug, 2008  |   Pubmed ID: 18598733
• Enhancement of Glioma Radiotherapy and Chemotherapy Response with Targeted Antibody Therapy Against Death Receptor 5
  International Journal of Radiation Oncology, Biology, Physics. Jun, 2008  |   Pubmed ID: 18474311
• Treatment of Human Colon Cancer Xenografts with TRA-8 Anti-death Receptor 5 Antibody Alone or in Combination with CPT-11
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2008  |   Pubmed ID: 18381960
• Anti-tumor Activity of the TRA-8 Anti-DR5 Antibody in Combination with Cisplatin in an Ex Vivo Human Cervical Cancer Model
  Gynecologic Oncology. Mar, 2008  |   Pubmed ID: 18177927
• TRA-8 Anti-DR5 Monoclonal Antibody and Gemcitabine Induce Apoptosis and Inhibit Radiologically Validated Orthotopic Pancreatic Tumor Growth
  Molecular Cancer Therapeutics. Dec, 2007  |   Pubmed ID: 18089714
• EGFR Genomic Gain and Aberrant Pathway Signaling in Pancreatic Cancer Patients
  The Journal of Surgical Research. Nov, 2007  |   Pubmed ID: 17950068
• Brief Overview of Preclinical and Clinical Studies in the Development of Intraperitoneal Radioimmunotherapy for Ovarian Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2007  |   Pubmed ID: 17875801
• Combination Treatment with TRA-8 Anti Death Receptor 5 Antibody and CPT-11 Induces Tumor Regression in an Orthotopic Model of Pancreatic Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2007  |   Pubmed ID: 17875786
• TRAIL-receptor Antibodies As a Potential Cancer Treatment
  Future Oncology (London, England). Aug, 2007  |   Pubmed ID: 17661715
• Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) and Its Therapeutic Potential in Breast and Gynecologic Cancers
  Gynecologic Oncology. Sep, 2007  |   Pubmed ID: 17602728
• ErbB3 Expression and Dimerization with EGFR Influence Pancreatic Cancer Cell Sensitivity to Erlotinib
  Cancer Biology & Therapy. Apr, 2007  |   Pubmed ID: 17457047
• Pancreatic Cancer Epidermal Growth Factor Receptor (EGFR) Intron 1 Polymorphism Influences Postoperative Patient Survival and in Vitro Erlotinib Response
  Annals of Surgical Oncology. Jul, 2007  |   Pubmed ID: 17453292
• Epidermal Growth Factor Receptor (EGFR) is Highly Conserved in Pancreatic Cancer
  Surgery. Apr, 2007  |   Pubmed ID: 17383523
• High-resolution Single-photon Emission Computed Tomography and X-ray Computed Tomography Imaging of Tc-99m-labeled Anti-DR5 Antibody in Breast Tumor Xenografts
  Molecular Cancer Therapeutics. Mar, 2007  |   Pubmed ID: 17363481
• Efficacy of Anti-death Receptor 5 (DR5) Antibody (TRA-8) Against Primary Human Ovarian Carcinoma Using a Novel Ex Vivo Tissue Slice Model
  Gynecologic Oncology. May, 2007  |   Pubmed ID: 17303227
• Oncolytic HSV-1 for the Treatment of Brain Tumours
  Herpes : the Journal of the IHMF. Nov, 2006  |   Pubmed ID: 17147910
• Treatment with Gemcitabine and TRA-8 Anti-death Receptor-5 MAb Reduces Pancreatic Adenocarcinoma Cell Viability in Vitro and Growth in Vivo
  Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Nov, 2006  |   Pubmed ID: 17114015
• Pretargeted Radioimmunotherapy
  International Journal of Radiation Oncology, Biology, Physics. 2006  |   Pubmed ID: 16979441
• TRAIL Receptor-targeted Therapy
  Future Oncology (London, England). Aug, 2006  |   Pubmed ID: 16922616
• Multiple Gene Expression Analyses in Paraffin-embedded Tissues by TaqMan Low-density Array: Application to Hedgehog and Wnt Pathway Analysis in Ovarian Endometrioid Adenocarcinoma
  The Journal of Molecular Diagnostics : JMD. Feb, 2006  |   Pubmed ID: 16436637
• Gene Delivery and Gene Therapy of Prostate Cancer
  Expert Opinion on Drug Delivery. Jan, 2006  |   Pubmed ID: 16370939
• Anti-tumor Activity of TRA-8 Anti-death Receptor 5 (DR5) Monoclonal Antibody in Combination with Chemotherapy and Radiation Therapy in a Cervical Cancer Model
  Gynecologic Oncology. Apr, 2006  |   Pubmed ID: 16271751
• Antitumor Efficacy of Capecitabine and Celecoxib in Irradiated and Lead-shielded, Contralateral Human BxPC-3 Pancreatic Cancer Xenografts: Clinical Implications of Abscopal Effects
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2005  |   Pubmed ID: 16361565
• Intraperitoneal Pretarget Radioimmunotherapy with CC49 Fusion Protein
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2005  |   Pubmed ID: 16299250
• Intraperitoneal Radioimmunotherapy with a Humanized Anti-TAG-72 (CC49) Antibody with a Deleted CH2 Region
  Cancer Biotherapy & Radiopharmaceuticals. Oct, 2005  |   Pubmed ID: 16248766
• The Small Heat Shock Protein Alpha B-crystallin is a Novel Inhibitor of TRAIL-induced Apoptosis That Suppresses the Activation of Caspase-3
  The Journal of Biological Chemistry. Mar, 2005  |   Pubmed ID: 15653686
• Radiotargeted Gene Therapy
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jan, 2005  |   Pubmed ID: 15653667
• Mechanisms of Resistance to Erbitux (anti-epidermal Growth Factor Receptor) Combination Therapy in Pancreatic Adenocarcinoma Cells
  Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Dec, 2004  |   Pubmed ID: 15585383
• Adenovirus-mediated FLT1-targeted Proapoptotic Gene Therapy of Human Prostate Cancer
  Molecular Therapy : the Journal of the American Society of Gene Therapy. Dec, 2004  |   Pubmed ID: 15564138
• Site-specifically Traced Drug Release and Biodistribution of a Paclitaxel-antibody Conjugate Toward Improvement of the Linker Structure
  Bioconjugate Chemistry. Nov-Dec, 2004  |   Pubmed ID: 15546192
• Gene Expression Imaging with Radiolabeled Peptides
  Annals of Nuclear Medicine. Jun, 2004  |   Pubmed ID: 15359919
• Anti-EGFR-mediated Radiosensitization As a Result of Augmented EGFR Expression
  International Journal of Radiation Oncology, Biology, Physics. 2004  |   Pubmed ID: 15142629
• Adenoviral Vector-mediated Augmentation of Epidermal Growth Factor Receptor (EGFr) Enhances the Radiosensitization Properties of Anti-EGFr Treatment in Prostate Cancer Cells
  International Journal of Radiation Oncology, Biology, Physics. Mar, 2004  |   Pubmed ID: 14967455
• Imaging and Therapy of Tumors Induced to Express Somatostatin Receptor by Gene Transfer Using Radiolabeled Peptides and Single Chain Antibody Constructs
  Seminars in Nuclear Medicine. Jan, 2004  |   Pubmed ID: 14735457
• Antitumor Efficacy of TRA-8 Anti-DR5 Monoclonal Antibody Alone or in Combination with Chemotherapy And/or Radiation Therapy in a Human Breast Cancer Model
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2003  |   Pubmed ID: 14506165
• Differential Responses by Pancreatic Carcinoma Cell Lines to Prolonged Exposure to Erbitux (IMC-C225) Anti-EGFR Antibody
  The Journal of Surgical Research. May, 2003  |   Pubmed ID: 12850474
• Three-dimensional Dose Model for the Comparison of 177Lu-HuCC49DeltaCH2 and 177Lu-HuCC49 Radioimunotherapy in Mice Bearing Intraperitoneal Xenografts
  Cancer Biotherapy & Radiopharmaceuticals. Apr, 2003  |   Pubmed ID: 12804050
• Synthesis and Biological Evaluation of Paclitaxel-C225 Conjugate As a Model for Targeted Drug Delivery
  Bioconjugate Chemistry. Mar-Apr, 2003  |   Pubmed ID: 12643740
• Invited Commentary: Targeting of 125I-labeled B Lymphocyte Stimulator
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Mar, 2003  |   Pubmed ID: 12621011
• An Adenovirus Encoding Proapoptotic Bax Synergistically Radiosensitizes Malignant Glioma
  International Journal of Radiation Oncology, Biology, Physics. Mar, 2003  |   Pubmed ID: 12605984
• Induction of Thymidine Phosphorylase in Both Irradiated and Shielded, Contralateral Human U87MG Glioma Xenografts: Implications for a Dual Modality Treatment Using Capecitabine and Irradiation
  Molecular Cancer Therapeutics. Oct, 2002  |   Pubmed ID: 12481438
• Treatment of Pancreatic Cancer Xenografts with Erbitux (IMC-C225) Anti-EGFR Antibody, Gemcitabine, and Radiation
  International Journal of Radiation Oncology, Biology, Physics. Nov, 2002  |   Pubmed ID: 12419447
• Adenovirus-mediated Transfer of BAX Driven by the Vascular Endothelial Growth Factor Promoter Induces Apoptosis in Lung Cancer Cells
  Molecular Therapy : the Journal of the American Society of Gene Therapy. Aug, 2002  |   Pubmed ID: 12161185
• Gamma Camera Dual Imaging with a Somatostatin Receptor and Thymidine Kinase After Gene Transfer with a Bicistronic Adenovirus in Mice
  Radiology. May, 2002  |   Pubmed ID: 11997547
• Synthesis of the First Diethylenetriaminepentahydroxamic Acid (DTPH) Bifunctional Chelating Agent
  Bioconjugate Chemistry. Mar-Apr, 2002  |   Pubmed ID: 11906271
• De Novo Synthesis of a New Diethylenetriaminepentaacetic Acid (DTPA) Bifunctional Chelating Agent
  Bioconjugate Chemistry. Mar-Apr, 2002  |   Pubmed ID: 11906270
• Rationales, Evidence, and Design Considerations for Fractionated Radioimmunotherapy
  Cancer. Feb, 2002  |   Pubmed ID: 11877764
• Targeted Radiotherapy with [(90)Y]-SMT 487 in Mice Bearing Human Nonsmall Cell Lung Tumor Xenografts Induced to Express Human Somatostatin Receptor Subtype 2 with an Adenoviral Vector
  Cancer. Feb, 2002  |   Pubmed ID: 11877760
• Model Prediction of Treatment Planning for Dose-fractionated Radioimmunotherapy
  Cancer. Feb, 2002  |   Pubmed ID: 11877755
• Intratumoral 5-fluorouracil Produced by Cytosine Deaminase/5-fluorocytosine Gene Therapy is Effective for Experimental Human Glioblastomas
  Cancer Research. Feb, 2002  |   Pubmed ID: 11830532
• Quantitation of Cytosine Deaminase MRNA by Real-time Reverse Transcription Polymerase Chain Reaction: a Sensitive Method for Assessing 5-fluorocytosine Toxicity in Vitro
  Analytical Biochemistry. Feb, 2002  |   Pubmed ID: 11814289