Dongsu Park Department of Molecular Human Genetics Baylor College of Medicine Biography Publications Institution JoVE Articles Dongsu Park I received my Ph.D. degree in Immunology from Baylor College of Medicine in 2007 and continued postdoctoral training in Stem Cell Biology with Dr. David T. Scadden at the MGH and Harvard Medical School until 2013. My early studies uncovered a novel regulatory mechanism of immune cells and dendritic cell survival mechanism to induce anti-cancer immunity. Later, I extended these researches to discover the in vivo kinetics of bone forming cells and in vivo identity of skeletal stem cells in periosteum (outer bone layer) and bone marrow. We now focus on uncovering skeletal stem cell heterogeneity, their specific regulators and novel therapeutic strategies targeting bone diseases, regeneration and aging. Publications Stress Hematopoiesis is Regulated by the Krüppel-like Transcription Factor ZBP-89 Stem Cells (Dayton, Ohio). Mar, 2014 | Pubmed ID: 24549639 Endogenous Bone Marrow MSCs Are Dynamic, Fate-restricted Participants in Bone Maintenance and Regeneration Cell Stem Cell. Mar, 2012 | Pubmed ID: 22385654 Activation of Wnt Signaling by Chemically Induced Dimerization of LRP5 Disrupts Cellular Homeostasis PloS One. Month, 2012 | Pubmed ID: 22303459 The Hematopoietic Stem Cell Niche Frontiers in Bioscience : a Journal and Virtual Library. Month, 2012 | Pubmed ID: 22201730 The Adaptor Protein Lad Associates with the G Protein Beta Subunit and Mediates Chemokine-dependent T-cell Migration Blood. Jun, 2007 | Pubmed ID: 17327418 An Essential Role for Akt1 in Dendritic Cell Function and Tumor Immunotherapy Nature Biotechnology. Dec, 2006 | Pubmed ID: 17143278 Echtzeit-Bildgebung der CCL5-induzierten Migration von periostalen Skelettstammzellen in Mäusen Laura Ortinau1,2, Kevin Lei1, Youngjae Jeong1, Dongsu Park1,2,3 1Department of Molecular & Human Genetics, Baylor College of Medicine, 2Center for Skeletal Biology, Baylor College of Medicine, 3Department of Pathology & Immunology, Baylor College of Medicine JoVE 61162 Developmental Biology Sequentiell Dongsu Park1, Joel A. Spencer2, Charles P. Lin2, David T. Scadden1 1Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Stem Cell Institute, 2Wellman Center for Photomedicine and Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School JoVE 51289 Medicine
Echtzeit-Bildgebung der CCL5-induzierten Migration von periostalen Skelettstammzellen in Mäusen Laura Ortinau1,2, Kevin Lei1, Youngjae Jeong1, Dongsu Park1,2,3 1Department of Molecular & Human Genetics, Baylor College of Medicine, 2Center for Skeletal Biology, Baylor College of Medicine, 3Department of Pathology & Immunology, Baylor College of Medicine JoVE 61162 Developmental Biology
Sequentiell Dongsu Park1, Joel A. Spencer2, Charles P. Lin2, David T. Scadden1 1Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Stem Cell Institute, 2Wellman Center for Photomedicine and Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School JoVE 51289 Medicine
