Douglas Kintner Waisman Center University of Wisconsin Biography Publications Institution JoVE Articles Douglas Kintner has not added a biography. If you are Douglas Kintner and would like to personalize this page please email our Author Liaison for assistance. Publications Suppression of Microglia Activation After Hypoxia-ischemia Results in Age-dependent Improvements in Neurologic Injury Journal of Neuroimmunology. Feb, 2016 | Pubmed ID: 26857490 ERα Signaling Is Required for TrkB-Mediated Hippocampal Neuroprotection in Female Neonatal Mice After Hypoxic Ischemic Encephalopathy(1,2,3) ENeuro. Jan-Feb, 2016 | Pubmed ID: 26839918 Hippocampal Increase of 5-hmC in the Glucocorticoid Receptor Gene Following Acute Stress Behavioural Brain Research. Jun, 2015 | Pubmed ID: 25746451 Sustained Na+/H+ Exchanger Activation Promotes Gliotransmitter Release from Reactive Hippocampal Astrocytes Following Oxygen-glucose Deprivation PloS One. 2014 | Pubmed ID: 24392123 Age-dependent Microglial Activation in Immature Brains After Hypoxia- Ischemia CNS & Neurological Disorders Drug Targets. May, 2013 | Pubmed ID: 23469850 TrkB Receptor Agonist 7, 8 Dihydroxyflavone Triggers Profound Gender- Dependent Neuroprotection in Mice After Perinatal Hypoxia and Ischemia CNS & Neurological Disorders Drug Targets. May, 2013 | Pubmed ID: 23469848 Inhibition of Na(+)-K(+)-2Cl(-) Cotransporter Isoform 1 Accelerates Temozolomide-mediated Apoptosis in Glioblastoma Cancer Cells Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2012 | Pubmed ID: 22759954 DHA Inhibits ER Ca2+ Release and ER Stress in Astrocytes Following in Vitro Ischemia Journal of Neurochemistry. Feb, 2012 | Pubmed ID: 22129278 Activation of Microglia Depends on Na+/H+ Exchange-mediated H+ Homeostasis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2010 | Pubmed ID: 21068326 Excessive Na+/H+ Exchange in Disruption of Dendritic Na+ and Ca2+ Homeostasis and Mitochondrial Dysfunction Following in Vitro Ischemia The Journal of Biological Chemistry. Nov, 2010 | Pubmed ID: 20817726 Endoplasmic Reticulum Ca2+ Signaling and Mitochondrial Cyt C Release in Astrocytes Following Oxygen and Glucose Deprivation Journal of Neurochemistry. Sep, 2010 | Pubmed ID: 20557423 Study of Na+/H+ Exchange-mediated PHi Regulations in Neuronal Soma and Neurites in Compartmentalized Microfluidic Devices Integrative Biology : Quantitative Biosciences from Nano to Macro. Jan, 2010 | Pubmed ID: 20473413 Activity-dependent Regulation of Mitochondrial Motility by Calcium and Na/K-ATPase at Nodes of Ranvier of Myelinated Nerves The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2010 | Pubmed ID: 20219989 Protein Aggregation in Neurons Following OGD: a Role for Na+ and Ca2+ Ionic Dysregulation Journal of Neurochemistry. Jan, 2010 | Pubmed ID: 19840218 Calcium Dysregulation Induces Apoptosis-inducing Factor Release: Cross-talk Between PARP-1- and Calpain-signaling Pathways Experimental Neurology. Aug, 2009 | Pubmed ID: 19427306 Endoplasmic Reticulum Ca2+ Dysregulation and Endoplasmic Reticulum Stress Following in Vitro Neuronal Ischemia: Role of Na+-K+-Cl- Cotransporter Journal of Neurochemistry. Aug, 2008 | Pubmed ID: 18507737 A Concerted Role of Na+ -K+ -Cl- Cotransporter and Na+/Ca2+ Exchanger in Ischemic Damage Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Apr, 2008 | Pubmed ID: 17912271 ERK1/2-p90RSK-mediated Phosphorylation of Na+/H+ Exchanger Isoform 1. A Role in Ischemic Neuronal Death The Journal of Biological Chemistry. Sep, 2007 | Pubmed ID: 17664275 AMPA-mediated Excitotoxicity in Oligodendrocytes: Role for Na(+)-K(+)-Cl(-) Co-transport and Reversal of Na(+)/Ca(2+) Exchanger Journal of Neurochemistry. Sep, 2007 | Pubmed ID: 17490438 Increased Tolerance to Ischemic Neuronal Damage by Knockdown of Na+-Ca2+ Exchanger Isoform 1 Annals of the New York Academy of Sciences. Mar, 2007 | Pubmed ID: 17446470 Role of Membrane Ion Transport Proteins in Cerebral Ischemic Damage Frontiers in Bioscience : a Journal and Virtual Library. Jan, 2007 | Pubmed ID: 17127336 Role of Na+-K+-Cl- Cotransport and Na+/Ca2+ Exchange in Mitochondrial Dysfunction in Astrocytes Following in Vitro Ischemia American Journal of Physiology. Cell Physiology. Mar, 2007 | Pubmed ID: 17035299 Decreased Neuronal Death in Na+/H+ Exchanger Isoform 1-null Mice After in Vitro and in Vivo Ischemia The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2005 | Pubmed ID: 16339021 Stimulation of Astrocyte Na+/H+ Exchange Activity in Response to in Vitro Ischemia Depends in Part on Activation of ERK1/2 American Journal of Physiology. Cell Physiology. Oct, 2005 | Pubmed ID: 15901600 Na(+)-dependent Chloride Transporter (NKCC1)-null Mice Exhibit Less Gray and White Matter Damage After Focal Cerebral Ischemia Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jan, 2005 | Pubmed ID: 15678112 Na-K-Cl Cotransporter-mediated Intracellular Na+ Accumulation Affects Ca2+ Signaling in Astrocytes in an in Vitro Ischemic Model The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2004 | Pubmed ID: 15509746 Increased Tolerance to Oxygen and Glucose Deprivation in Astrocytes from Na(+)/H(+) Exchanger Isoform 1 Null Mice American Journal of Physiology. Cell Physiology. Jul, 2004 | Pubmed ID: 15013953 GABA-mediated Trophic Effect on Oligodendrocytes Requires Na-K-2Cl Cotransport Activity Journal of Neurophysiology. Aug, 2003 | Pubmed ID: 12904508 Na-K-Cl Cotransporter Contributes to Glutamate-mediated Excitotoxicity The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2003 | Pubmed ID: 12832529 Cross Talk Between the GABA(A) Receptor and the Na-K-Cl Cotransporter is Mediated by Intracellular Cl- Journal of Neurophysiology. Jan, 2003 | Pubmed ID: 12522168 Astrocytes from Na(+)-K(+)-Cl(-) Cotransporter-null Mice Exhibit Absence of Swelling and Decrease in EAA Release American Journal of Physiology. Cell Physiology. May, 2002 | Pubmed ID: 11940530 Contribution of Na(+)-K(+)-Cl(-) Cotransporter to High-[K(+)](o)- Induced Swelling and EAA Release in Astrocytes American Journal of Physiology. Cell Physiology. May, 2002 | Pubmed ID: 11940529 Sex Differences in Mouse Hippocampal Astrocytes after In-Vitro Ischemia Vishal Chanana1, Abdulfettah Tumturk2, Douglas Kintner1, Eshwar Udho1, Peter Ferrazzano1,3, Pelin Cengiz1,3 1Waisman Center, University of Wisconsin, 2Department of Neurological Surgery, University of Wisconsin, 3Department of Pediatrics, University of Wisconsin JoVE 53695 Neuroscience
Sex Differences in Mouse Hippocampal Astrocytes after In-Vitro Ischemia Vishal Chanana1, Abdulfettah Tumturk2, Douglas Kintner1, Eshwar Udho1, Peter Ferrazzano1,3, Pelin Cengiz1,3 1Waisman Center, University of Wisconsin, 2Department of Neurological Surgery, University of Wisconsin, 3Department of Pediatrics, University of Wisconsin JoVE 53695 Neuroscience