Dunja Bruder Immune Regulation Group Helmholtz Centre for Infection Research Biography Publications Institution JoVE Articles Dunja Bruder has not added a biography. If you are Dunja Bruder and would like to personalize this page please email our Author Liaison for assistance. Publications Eosinophilic Pulmonary Vasculitis As a Manifestation of the Hyperinflammatory Phase of COVID-19 The Journal of Allergy and Clinical Immunology. 01, 2021 | Pubmed ID: 33139059 Resolved Influenza A Virus Infection Has Extended Effects on Lung Homeostasis and Attenuates Allergic Airway Inflammation in a Mouse Model Microorganisms. Nov, 2020 | Pubmed ID: 33260910 NMP4: a Nuclear Driver of Innate Inflammatory Responses During Influenza A Virus Infection Cellular & Molecular Immunology. Dec, 2020 | Pubmed ID: 32747686 Topological Data Analysis to Model the Shape of Immune Responses During Co-infections Communications in Nonlinear Science & Numerical Simulation. Jun, 2020 | Pubmed ID: 32288422 ADAP Promotes Degranulation and Migration of NK Cells Primed During Infection in Mice Frontiers in Immunology. 2019 | Pubmed ID: 32038647 Mucosal CD8+ T Cell Responses Induced by an MCMV Based Vaccine Vector Confer Protection Against Influenza Challenge PLoS Pathogens. 09, 2019 | Pubmed ID: 31525249 Neutralization of Pro-inflammatory Cytokines During Secondary Infection Post Influenza A Virus Infection Frontiers in Immunology. 2019 | Pubmed ID: 31474978 The STING Activator C-di-AMP Exerts Superior Adjuvant Properties Than the Formulation Poly(I:C)/CpG After Subcutaneous Vaccination with Soluble Protein Antigen or DEC-205-mediated Antigen Targeting to Dendritic Cells Vaccine. 08, 2019 | Pubmed ID: 31320219 Essential Role of IκB for in Vivo CD4 T-cell Activation, Proliferation, and Th1-cell Differentiation During Listeria Monocytogenes Infection in Mice European Journal of Immunology. 09, 2019 | Pubmed ID: 31049948 Gamma Secretase Dependent Release of the CD44 Cytoplasmic Tail Upregulates IFI16 in Cd44-/- Tumor Cells, MEFs and Macrophages PloS One. 2018 | Pubmed ID: 30540779 Activates Human Mucosal-Associated Invariant T Cells Frontiers in Microbiology. 2018 | Pubmed ID: 30410474 Presence of Infected Gr-1CD11bCD11c Monocytic Myeloid Derived Suppressor Cells Subverts T Cell Response and Is Associated With Impaired Dendritic Cell Function in -Infected Mice Frontiers in Immunology. 2018 | Pubmed ID: 30386330 Hemodialysis-related Changes in Phenotypical Features of Monocytes Scientific Reports. 09, 2018 | Pubmed ID: 30228352 Respiratory Carriage is Associated with Broad Phenotypic Alterations of Peripheral CD4⁺CD25⁺ T Cells and Differentially Affects Immune Responses to Secondary Non-Infectious and Infectious Stimuli in Mice International Journal of Molecular Sciences. Sep, 2018 | Pubmed ID: 30200513 Proteomic Definition of Human Mucosal-associated Invariant T cells Determines Their Unique Molecular Effector Phenotype European Journal of Immunology. 08, 2018 | Pubmed ID: 29749611 Respiratory Influenza A Virus Infection Triggers Local and Systemic Natural Killer Cell Activation Toll-Like Receptor 7 Frontiers in Immunology. 2018 | Pubmed ID: 29497422 Chronic Lung Inflammation Primes Humoral Immunity and Augments Antipneumococcal Resistance Scientific Reports. 07, 2017 | Pubmed ID: 28694492 IL-33: a Jack of All Trades in the Orchestration of Respiratory Antibacterial Immunity Cellular & Molecular Immunology. Jul, 2017 | Pubmed ID: 28690328 C-REL and IκB Govern Common and Independent Steps of Regulatory T Cell Development from Novel CD122-Expressing Pre-Precursors Journal of Immunology (Baltimore, Md. : 1950). 08, 2017 | Pubmed ID: 28652399 Targeted Antigen Delivery to Dendritic Cells Elicits Robust Antiviral T Cell-mediated Immunity in the Liver Scientific Reports. Mar, 2017 | Pubmed ID: 28266658 Soluble CD200 Correlates With Interleukin-6 Levels in Sera of COPD Patients: Potential Implication of the CD200/CD200R Axis in the Disease Course Lung. 02, 2017 | Pubmed ID: 27864635 Mechanism of Granuloma Formation in Sarcoidosis Current Opinion in Hematology. 01, 2017 | Pubmed ID: 27755127 ADAP Plays a Pivotal Role in CD4+ T Cell Activation but is Only Marginally Involved in CD8+ T Cell Activation, Differentiation, and Immunity to Pathogens Journal of Leukocyte Biology. 02, 2017 | Pubmed ID: 27605210 Hierarchical Effects of Pro-inflammatory Cytokines on the Post-influenza Susceptibility to Pneumococcal Coinfection Scientific Reports. 11, 2016 | Pubmed ID: 27872472 A Cell Culture-derived Whole Virus Influenza A Vaccine Based on Magnetic Sulfated Cellulose Particles Confers Protection in Mice Against Lethal Influenza A Virus Infection Vaccine. 12, 2016 | Pubmed ID: 27816372 Influenza A Virus Infection Predisposes Hosts to Secondary Infection with Different Streptococcus Pneumoniae Serotypes with Similar Outcome but Serotype-Specific Manifestation Infection and Immunity. Dec, 2016 | Pubmed ID: 27647871 Oseltamivir PK/PD Modeling and Simulation to Evaluate Treatment Strategies Against Influenza-Pneumococcus Coinfection Frontiers in Cellular and Infection Microbiology. 2016 | Pubmed ID: 27379214 Alveolar Type II Epithelial Cells Contribute to the Anti-Influenza A Virus Response in the Lung by Integrating Pathogen- and Microenvironment-Derived Signals MBio. May, 2016 | Pubmed ID: 27143386 ImmunoPET/MR Imaging Allows Specific Detection of Aspergillus Fumigatus Lung Infection in Vivo Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26787852 Modeling Influenza Virus Infection: A Roadmap for Influenza Research Viruses. Oct, 2015 | Pubmed ID: 26473911 Erratum To: Morphological and Functional Alterations of Alveolar Macrophages in a Murine Model of Chronic Inflammatory Lung Disease Lung. Dec, 2015 | Pubmed ID: 26459043 Morphological and Functional Alterations of Alveolar Macrophages in a Murine Model of Chronic Inflammatory Lung Disease Lung. Dec, 2015 | Pubmed ID: 26319657 First Genomic Analysis of Dendritic Cells from Lung and Draining Lymph Nodes in Murine Asthma International Journal of Genomics. 2015 | Pubmed ID: 25811019 Ly6C(high) Monocytes Control Cerebral Toxoplasmosis Journal of Immunology (Baltimore, Md. : 1950). Apr, 2015 | Pubmed ID: 25710908 Evidence for a Causal Link Between Adaptor Protein PDZK1 Downregulation and Na⁺/H⁺ Exchanger NHE3 Dysfunction in Human and Murine Colitis Pflugers Archiv : European Journal of Physiology. Aug, 2015 | Pubmed ID: 25271043 Attenuation of Immune-mediated Influenza Pneumonia by Targeting the Inducible Co-stimulator (ICOS) Molecule on T Cells PloS One. 2014 | Pubmed ID: 25029240 Interferon Regulatory Factor-1 Protects from Fatal Neurotropic Infection with Vesicular Stomatitis Virus by Specific Inhibition of Viral Replication in Neurons PLoS Pathogens. Mar, 2014 | Pubmed ID: 24675692 ChIP-on-chip Analysis Identifies IL-22 As Direct Target Gene of Ectopically Expressed FOXP3 Transcription Factor in Human T Cells BMC Genomics. Dec, 2012 | Pubmed ID: 23244505 TLR7 Contributes to the Rapid Progression but Not to the Overall Fatal Outcome of Secondary Pneumococcal Disease Following Influenza A Virus Infection Journal of Innate Immunity. Nov, 2012 | Pubmed ID: 23154432 IL-4 Attenuates Pulmonary Epithelial Cell-mediated Suppression of T Cell Priming PloS One. 2012 | Pubmed ID: 23029313 CD8+ T Cells Responding to Alveolar Self-Antigen Lack CD25 Expression and Fail to Precipitate Autoimmunity American Journal of Respiratory Cell and Molecular Biology. Dec, 2012 | Pubmed ID: 22984087 Therapeutic Intervention in Cancer and Chronic Viral Infections: Antibody Mediated Manipulation of PD-1/PD-L1 Interaction Reviews on Recent Clinical Trials. Feb, 2012 | Pubmed ID: 22023178 Expression QTL Mapping in Regulatory and Helper T Cells from the BXD Family of Strains Reveals Novel Cell-specific Genes, Gene-gene Interactions and Candidate Genes for Auto-immune Disease BMC Genomics. 2011 | Pubmed ID: 22182475 Senescence Surveillance of Pre-malignant Hepatocytes Limits Liver Cancer Development Nature. Nov, 2011 | Pubmed ID: 22080947 Human Regulatory T Cells in Allogeneic Stem Cell Transplantation Blood. Sep, 2011 | Pubmed ID: 21778340 New Insights into the Molecular Pathology of Radiation-induced Pneumopathy Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Oct, 2011 | Pubmed ID: 21722981 CD4+CD25+Foxp3+ Regulatory T Cells Are Dispensable for Controlling CD8+ T Cell-mediated Lung Inflammation Journal of Immunology (Baltimore, Md. : 1950). Jun, 2011 | Pubmed ID: 21518973 Inhibition of Lymphocyte Trafficking Shields the Brain Against Deleterious Neuroinflammation After Stroke Brain : a Journal of Neurology. Mar, 2011 | Pubmed ID: 21354973 CX3CR1+ CD8alpha+ Dendritic Cells Are a Steady-state Population Related to Plasmacytoid Dendritic Cells Proceedings of the National Academy of Sciences of the United States of America. Aug, 2010 | Pubmed ID: 20679228 Novel Reporter Mouse Reveals Constitutive and Inflammatory Expression of IFN-beta in Vivo Journal of Immunology (Baltimore, Md. : 1950). Sep, 2009 | Pubmed ID: 19667093 Frequency and Gene Expression Profile of Regulatory T Cells in Renal Cell Carcinoma Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine. 2009 | Pubmed ID: 19609102 Host Genetic Background Strongly Influences the Response to Influenza a Virus Infections PloS One. 2009 | Pubmed ID: 19293935 Increased Susceptibility for Superinfection with Streptococcus Pneumoniae During Influenza Virus Infection is Not Caused by TLR7-mediated Lymphopenia PloS One. 2009 | Pubmed ID: 19290047 Alveolar Type II Epithelial Cells Present Antigen to CD4(+) T Cells and Induce Foxp3(+) Regulatory T Cells American Journal of Respiratory and Critical Care Medicine. Mar, 2009 | Pubmed ID: 19096007 Probiotic Escherichia Coli Nissle 1917 Inhibits Leaky Gut by Enhancing Mucosal Integrity PloS One. 2007 | Pubmed ID: 18074031 Chronic Antigen Stimulation in Vivo Induces a Distinct Population of Antigen-specific Foxp3 CD25 Regulatory T Cells Journal of Immunology (Baltimore, Md. : 1950). Dec, 2007 | Pubmed ID: 18056346 Phenotypic Alterations in Type II Alveolar Epithelial Cells in CD4+ T Cell Mediated Lung Inflammation Respiratory Research. 2007 | Pubmed ID: 17610738 Intestinal Epithelial Antigen Induces CD4+ T Cells with Regulatory Phenotype in a Transgenic Autoimmune Mouse Model Annals of the New York Academy of Sciences. Aug, 2006 | Pubmed ID: 17057222 Autoimmune-mediated Intestinal Inflammation-impact and Regulation of Antigen-specific CD8+ T Cells Gastroenterology. Aug, 2006 | Pubmed ID: 16890605 Cellular Immunity and Lung Injury in Respiratory Virus Infection Viral Immunology. 2006 | Pubmed ID: 16817757 G Protein-coupled Receptor 83 Overexpression in Naive CD4+CD25- T Cells Leads to the Induction of Foxp3+ Regulatory T Cells in Vivo Journal of Immunology (Baltimore, Md. : 1950). Jul, 2006 | Pubmed ID: 16785516 Lung Epithelial NF-kappaB and Stat1 Signaling in Response to CD8+ T Cell Antigen Recognition Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. May, 2006 | Pubmed ID: 16689660 Multiple Synergizing Factors Contribute to the Strength of the CD8+ T Cell Response Against Listeriolysin O International Immunology. Jan, 2006 | Pubmed ID: 16291651 On the Edge of Autoimmunity: T-cell Stimulation by Steady-state Dendritic Cells Prevents Autoimmune Diabetes Diabetes. Dec, 2005 | Pubmed ID: 16306354 Intestinal Immunity of Escherichia Coli NISSLE 1917: a Safe Carrier for Therapeutic Molecules FEMS Immunology and Medical Microbiology. Mar, 2005 | Pubmed ID: 15708311 Characterization of a B220+ Lymphoid Cell Subpopulation with Immune Modulatory Functions in Nasal-associated Lymphoid Tissues Journal of Immunology (Baltimore, Md. : 1950). Feb, 2005 | Pubmed ID: 15661888 CD4 T Lymphocyte-mediated Lung Disease: Steady State Between Pathological and Tolerogenic Immune Reactions American Journal of Respiratory and Critical Care Medicine. Dec, 2004 | Pubmed ID: 15306530 Neuropilin-1: a Surface Marker of Regulatory T Cells European Journal of Immunology. Mar, 2004 | Pubmed ID: 14991591 Vitro ve In Vivo'da Fare Dendritik Hücrelerini Hedeflemek için Tam Uzunlukta Proteinli Saflaştırılmış DEC-205 Yönlendirilmiş Antikorun Kimyasal Konjugasyonu Julia Volckmar1,2, Laura Knop1,2,3, Tatjana Hirsch1, Sarah Frentzel1,2, Christian Erck4, Marco van Ham4, Sabine Stegemann-Koniszewski*1,2,5, Dunja Bruder*1,2 1Immune Regulation Group, Helmholtz Centre for Infection Research, 2Infection Immunology Group, Institute of Medical Microbiology, Infection Prevention and Control, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, 3Institute for Molecular and Clinical Immunology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, 4Cellular Proteome Research, Helmholtz Centre for Infection Research, 5Experimental Pneumology, University Hospital of Pneumology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg JoVE 62018 Cancer Research Fonksiyonel ve Moleküler Çalışmalar Birincil murin Tip II alveol epitel hücrelerinde akım sitometri İzolasyonu Marcus Gereke1,2, Andrea Autengruber1,2, Lothar Gröbe3, Andreas Jeron2, Dunja Bruder1,2, Sabine Stegemann-Koniszewski1 1Research Group Immune Regulation, Helmholtz Centre for Infection Research, 2Research Group Infection Immunology, Institute of Medical Microbiology, Otto-von-Guericke University, 3Department of Experimental Immunology, Helmholtz Centre for Infection Research JoVE 4322 Immunology and Infection
Vitro ve In Vivo'da Fare Dendritik Hücrelerini Hedeflemek için Tam Uzunlukta Proteinli Saflaştırılmış DEC-205 Yönlendirilmiş Antikorun Kimyasal Konjugasyonu Julia Volckmar1,2, Laura Knop1,2,3, Tatjana Hirsch1, Sarah Frentzel1,2, Christian Erck4, Marco van Ham4, Sabine Stegemann-Koniszewski*1,2,5, Dunja Bruder*1,2 1Immune Regulation Group, Helmholtz Centre for Infection Research, 2Infection Immunology Group, Institute of Medical Microbiology, Infection Prevention and Control, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, 3Institute for Molecular and Clinical Immunology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, 4Cellular Proteome Research, Helmholtz Centre for Infection Research, 5Experimental Pneumology, University Hospital of Pneumology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg JoVE 62018 Cancer Research
Fonksiyonel ve Moleküler Çalışmalar Birincil murin Tip II alveol epitel hücrelerinde akım sitometri İzolasyonu Marcus Gereke1,2, Andrea Autengruber1,2, Lothar Gröbe3, Andreas Jeron2, Dunja Bruder1,2, Sabine Stegemann-Koniszewski1 1Research Group Immune Regulation, Helmholtz Centre for Infection Research, 2Research Group Infection Immunology, Institute of Medical Microbiology, Otto-von-Guericke University, 3Department of Experimental Immunology, Helmholtz Centre for Infection Research JoVE 4322 Immunology and Infection
