Ed Lein

Publications

• Cell Type Discovery and Representation in the Era of High-content Single Cell Phenotyping
  BMC Bioinformatics. Dec, 2017  |   Pubmed ID: 29322913
• The Human Cell Atlas
  ELife. 12, 2017  |   Pubmed ID: 29206104
• STRT-seq-2i: Dual-index 5' Single Cell and Nucleus RNA-seq on an Addressable Microwell Array
  Scientific Reports. Nov, 2017  |   Pubmed ID: 29180631
• Molecular and Cellular Reorganization of Neural Circuits in the Human Lineage
  Science (New York, N.Y.). 11, 2017  |   Pubmed ID: 29170230
• Neuropathological and Transcriptomic Characteristics of the Aged Brain
  ELife. Nov, 2017  |   Pubmed ID: 29120328
• The Promise of Spatial Transcriptomics for Neuroscience in the Era of Molecular Cell Typing
  Science (New York, N.Y.). 10, 2017  |   Pubmed ID: 28983044
• SmartScope2: Simultaneous Imaging and Reconstruction of Neuronal Morphology
  Scientific Reports. Aug, 2017  |   Pubmed ID: 28839271
• Transcriptomic Perspectives on Neocortical Structure, Development, Evolution, and Disease
  Annual Review of Neuroscience. Jul, 2017  |   Pubmed ID: 28661727
• Fast Assembling of Neuron Fragments in Serial 3D Sections
  Brain Informatics. Sep, 2017  |   Pubmed ID: 28365869
• Single-Cell Profiling of an In Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation
  Neuron. Mar, 2017  |   Pubmed ID: 28279351
• Biallelic Mutations in Human DCC Cause Developmental Split-brain Syndrome
  Nature Genetics. Apr, 2017  |   Pubmed ID: 28250456
• Comprehensive Cellular-resolution Atlas of the Adult Human Brain
  The Journal of Comparative Neurology. Nov, 2016  |   Pubmed ID: 27418273
• A Comprehensive Transcriptional Map of Primate Brain Development
  Nature. 07, 2016  |   Pubmed ID: 27409810
• Comments and General Discussion on "The Anatomical Problem Posed by Brain Complexity and Size: A Potential Solution"
  Frontiers in Neuroanatomy. 2016  |   Pubmed ID: 27375436
• Using Single Nuclei for RNA-seq to Capture the Transcriptome of Postmortem Neurons
  Nature Protocols. Mar, 2016  |   Pubmed ID: 26890679
• Canonical Genetic Signatures of the Adult Human Brain
  Nature Neuroscience. Dec, 2015  |   Pubmed ID: 26571460
• Spatiotemporal Dynamics of the Postnatal Developing Primate Brain Transcriptome
  Human Molecular Genetics. Aug, 2015  |   Pubmed ID: 25954031
• Cortical Fast-spiking Parvalbumin Interneurons Enwrapped in the Perineuronal Net Express the Metallopeptidases Adamts8, Adamts15 and Neprilysin
  Molecular Psychiatry. Feb, 2015  |   Pubmed ID: 25510509
• Spatial Mapping of Structural and Connectional Imaging Data for the Developing Human Brain with Diffusion Tensor Imaging
  Methods (San Diego, Calif.). Feb, 2015  |   Pubmed ID: 25448302
• Correlated Gene Expression and Target Specificity Demonstrate Excitatory Projection Neuron Diversity
  Cerebral Cortex (New York, N.Y. : 1991). Feb, 2015  |   Pubmed ID: 24014670
• Convergent Transcriptional Specializations in the Brains of Humans and Song-learning Birds
  Science (New York, N.Y.). Dec, 2014  |   Pubmed ID: 25504733
• Functional Organization of the Hippocampal Longitudinal Axis
  Nature Reviews. Neuroscience. Oct, 2014  |   Pubmed ID: 25234264
• Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development
  Cell. Jul, 2014  |   Pubmed ID: 24998929
• Transcriptional Landscape of the Prenatal Human Brain
  Nature. Apr, 2014  |   Pubmed ID: 24695229
• Improving Reliability and Absolute Quantification of Human Brain Microarray Data by Filtering and Scaling Probes Using RNA-Seq
  BMC Genomics. Feb, 2014  |   Pubmed ID: 24564186
• The Complete Genome Sequence of a Neanderthal from the Altai Mountains
  Nature. Jan, 2014  |   Pubmed ID: 24352235
• Conserved Molecular Signatures of Neurogenesis in the Hippocampal Subgranular Zone of Rodents and Primates
  Development (Cambridge, England). Nov, 2013  |   Pubmed ID: 24154525
• An Anatomically Comprehensive Atlas of the Adult Human Brain Transcriptome
  Nature. Sep, 2012  |   Pubmed ID: 22996553
• Large-scale Cellular-resolution Gene Profiling in Human Neocortex Reveals Species-specific Molecular Signatures
  Cell. Apr, 2012  |   Pubmed ID: 22500809
• Transcriptional Architecture of the Primate Neocortex
  Neuron. Mar, 2012  |   Pubmed ID: 22445337
• Multi-scale Correlation Structure of Gene Expression in the Brain
  Neural Networks : the Official Journal of the International Neural Network Society. Nov, 2011  |   Pubmed ID: 21764550
• Cell-type-specific Consequences of Reelin Deficiency in the Mouse Neocortex, Hippocampus, and Amygdala
  The Journal of Comparative Neurology. Aug, 2011  |   Pubmed ID: 21491433
• Divergent and Nonuniform Gene Expression Patterns in Mouse Brain
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010  |   Pubmed ID: 20956311
• A Robust and High-throughput Cre Reporting and Characterization System for the Whole Mouse Brain
  Nature Neuroscience. Jan, 2010  |   Pubmed ID: 20023653
• Surface-based Mapping of Gene Expression and Probabilistic Expression Maps in the Mouse Cortex
  Methods (San Diego, Calif.). Feb, 2010  |   Pubmed ID: 19818854
• Areal and Laminar Differentiation in the Mouse Neocortex Using Large Scale Gene Expression Data
  Methods (San Diego, Calif.). Feb, 2010  |   Pubmed ID: 19800006
• Shifting the Paradigm: New Approaches for Characterizing and Classifying Neurons
  Current Opinion in Neurobiology. Oct, 2009  |   Pubmed ID: 19896835
• An Anatomic Gene Expression Atlas of the Adult Mouse Brain
  Nature Neuroscience. Mar, 2009  |   Pubmed ID: 19219037
• Genomic Anatomy of the Hippocampus
  Neuron. Dec, 2008  |   Pubmed ID: 19109908
• New Developments in Sleep Research: Molecular Genetics, Gene Expression, and Systems Neurobiology
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2008  |   Pubmed ID: 19005045
• Quantitative Methods for Genome-scale Analysis of in Situ Hybridization and Correlation with Microarray Data
  Genome Biology. Jan, 2008  |   Pubmed ID: 18234097
• Neuroinformatics for Genome-wide 3D Gene Expression Mapping in the Mouse Brain
  IEEE/ACM Transactions on Computational Biology and Bioinformatics. Jul-Sep, 2007  |   Pubmed ID: 17666758
• Genome-wide Atlas of Gene Expression in the Adult Mouse Brain
  Nature. Jan, 2007  |   Pubmed ID: 17151600