Edwin W. Rubel Department of Otolaryngology-Head and Neck Surgery, Virginia Merrill Bloedel Hearing Research Center University of Washington Biography Publications Institution JoVE Articles Edwin W. Rubel has not added a biography. If you are Edwin W. Rubel and would like to personalize this page please email our Author Liaison for assistance. Publications Screening for Chemicals That Affect Hair Cell Death and Survival in the Zebrafish Lateral Line Hearing Research. Jan, 2012 | Pubmed ID: 22310494 Tonotopic Organization of the Superior Olivary Nucleus in the Chicken Auditory Brainstem The Journal of Comparative Neurology. Nov, 2011 | Pubmed ID: 22102107 Inhibition in the Balance: Binaurally Coupled Inhibitory Feedback in Sound Localization Circuitry Journal of Neurophysiology. Jul, 2011 | Pubmed ID: 21525367 Relative Input Strength Rapidly Regulates Dendritic Structure of Chick Auditory Brainstem Neurons The Journal of Comparative Neurology. Oct, 2011 | Pubmed ID: 21500196 Topography and Morphology of the Inhibitory Projection from Superior Olivary Nucleus to Nucleus Laminaris in Chickens (Gallus Gallus) The Journal of Comparative Neurology. Feb, 2011 | Pubmed ID: 21165979 GABAergic Inhibition Sharpens the Frequency Tuning and Enhances Phase Locking in Chicken Nucleus Magnocellularis Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2010 | Pubmed ID: 20826670 Dynamic Spike Thresholds During Synaptic Integration Preserve and Enhance Temporal Response Properties in the Avian Cochlear Nucleus The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2010 | Pubmed ID: 20826669 Development of Glutamatergic Synaptic Transmission in Binaural Auditory Neurons Journal of Neurophysiology. Sep, 2010 | Pubmed ID: 20668278 Chemical Screening for Hair Cell Loss and Protection in the Zebrafish Lateral Line Zebrafish. Mar, 2010 | Pubmed ID: 20192852 Drug Screening for Hearing Loss: Using the Zebrafish Lateral Line to Screen for Drugs That Prevent and Cause Hearing Loss Drug Discovery Today. Apr, 2010 | Pubmed ID: 20096805 Deafness and Retinal Degeneration in a Novel USH1C Knock-in Mouse Model Developmental Neurobiology. Mar, 2010 | Pubmed ID: 20095043 Mechanisms for Adjusting Interaural Time Differences to Achieve Binaural Coincidence Detection The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2010 | Pubmed ID: 20053889 A Simple Method for Multiday Imaging of Slice Cultures Microscopy Research and Technique. Jan, 2010 | Pubmed ID: 19565635 Effects of Restricted Basilar Papillar Lesions and Hair Cell Regeneration on Auditory Forebrain Frequency Organization in Adult European Starlings The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2009 | Pubmed ID: 19474314 Compartment-specific Regulation of Plasma Membrane Calcium ATPase Type 2 in the Chick Auditory Brainstem The Journal of Comparative Neurology. Jun, 2009 | Pubmed ID: 19365819 Cisplatin-induced Hair Cell Death Requires STAT1 and is Attenuated by Epigallocatechin Gallate The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2009 | Pubmed ID: 19321781 Extracellular Divalent Cations Modulate Aminoglycoside-induced Hair Cell Death in the Zebrafish Lateral Line Hearing Research. Jul, 2009 | Pubmed ID: 19285547 Response of Mechanosensory Hair Cells of the Zebrafish Lateral Line to Aminoglycosides Reveals Distinct Cell Death Pathways Hearing Research. Jul, 2009 | Pubmed ID: 19285126 Identification of FDA-approved Drugs and Bioactives That Protect Hair Cells in the Zebrafish (Danio Rerio) Lateral Line and Mouse (Mus Musculus) Utricle Journal of the Association for Research in Otolaryngology : JARO. Jun, 2009 | Pubmed ID: 19241104 CC2D2A is Mutated in Joubert Syndrome and Interacts with the Ciliopathy-associated Basal Body Protein CEP290 American Journal of Human Genetics. Nov, 2008 | Pubmed ID: 18950740 Afferent Deprivation Elicits a Transcriptional Response Associated with Neuronal Survival After a Critical Period in the Mouse Cochlear Nucleus The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2008 | Pubmed ID: 18945907 Three-dimensional Imaging of the Intact Mouse Cochlea by Fluorescent Laser Scanning Confocal Microscopy Hearing Research. Sep, 2008 | Pubmed ID: 18573326 Identification of Genetic and Chemical Modulators of Zebrafish Mechanosensory Hair Cell Death PLoS Genetics. Feb, 2008 | Pubmed ID: 18454195 Using the Zebrafish Lateral Line to Screen for Ototoxicity Journal of the Association for Research in Otolaryngology : JARO. Jun, 2008 | Pubmed ID: 18408970 Notch Signaling Regulates the Extent of Hair Cell Regeneration in the Zebrafish Lateral Line The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2008 | Pubmed ID: 18305259 Cisplatin-induced Hair Cell Loss in Zebrafish (Danio Rerio) Lateral Line Hearing Research. Nov, 2007 | Pubmed ID: 17709218 Auditory Feedback and Song Production Do Not Regulate Seasonal Growth of Song Control Circuits in Adult White-crowned Sparrows The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2007 | Pubmed ID: 17581968 Ultrastructural Analysis of Aminoglycoside-induced Hair Cell Death in the Zebrafish Lateral Line Reveals an Early Mitochondrial Response The Journal of Comparative Neurology. Jun, 2007 | Pubmed ID: 17394157 A Developmental Switch to GABAergic Inhibition Dependent on Increases in Kv1-type K+ Currents The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2007 | Pubmed ID: 17314306 Development of Spontaneous Miniature EPSCs in Mouse AVCN Neurons During a Critical Period of Afferent-dependent Neuron Survival Journal of Neurophysiology. Jan, 2007 | Pubmed ID: 17079338 JNK Signaling in Neomycin-induced Vestibular Hair Cell Death Hearing Research. Nov, 2006 | Pubmed ID: 17005344 Afferent Regulation of Neuron Number in the Cochlear Nucleus: Cellular and Molecular Analyses of a Critical Period Hearing Research. Jun-Jul, 2006 | Pubmed ID: 16874907 Formation of the Avian Nucleus Magnocellularis from the Auditory Anlage The Journal of Comparative Neurology. Oct, 2006 | Pubmed ID: 16874806 Lateral Line Hair Cell Maturation is a Determinant of Aminoglycoside Susceptibility in Zebrafish (Danio Rerio) Hearing Research. Mar, 2006 | Pubmed ID: 16459035 The Level and Integrity of Synaptic Input Regulates Dendrite Structure The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2006 | Pubmed ID: 16452677 Mechanisms of Hair Cell Death and Protection Current Opinion in Otolaryngology & Head and Neck Surgery. Dec, 2005 | Pubmed ID: 16282762 Gene Expression Differences over a Critical Period of Afferent-dependent Neuron Survival in the Mouse Auditory Brainstem The Journal of Comparative Neurology. Dec, 2005 | Pubmed ID: 16261529 Expression of GABA(B) Receptor in the Avian Auditory Brainstem: Ontogeny, Afferent Deprivation, and Ultrastructure The Journal of Comparative Neurology. Aug, 2005 | Pubmed ID: 15977167 Avian Superior Olivary Nucleus Provides Divergent Inhibitory Input to Parallel Auditory Pathways The Journal of Comparative Neurology. Jan, 2005 | Pubmed ID: 15558730 GABA(B) Receptor Activation Modulates GABA(A) Receptor-mediated Inhibition in Chicken Nucleus Magnocellularis Neurons Journal of Neurophysiology. Mar, 2005 | Pubmed ID: 15483063 Activation of Metabotropic Glutamate Receptors Inhibits High-voltage-gated Calcium Channel Currents of Chicken Nucleus Magnocellularis Neurons Journal of Neurophysiology. Mar, 2005 | Pubmed ID: 15371493 Overexpression of Bcl-2 Prevents Neomycin-induced Hair Cell Death and Caspase-9 Activation in the Adult Mouse Utricle in Vitro Journal of Neurobiology. Jul, 2004 | Pubmed ID: 15188275 Tonotopic Gradients of Eph Family Proteins in the Chick Nucleus Laminaris During Synaptogenesis Journal of Neurobiology. Jul, 2004 | Pubmed ID: 15188270 Round Window Gentamicin Application: an Inner Ear Hair Cell Damage Protocol for the Mouse Hearing Research. Jun, 2004 | Pubmed ID: 15157964 EphA4 Signaling Promotes Axon Segregation in the Developing Auditory System Developmental Biology. May, 2004 | Pubmed ID: 15081355 A New Method for Imaging and 3D Reconstruction of Mammalian Cochlea by Fluorescent Confocal Microscopy Brain Research. Mar, 2004 | Pubmed ID: 15053969 Activity-dependent Regulation of the Potassium Channel Subunits Kv1.1 and Kv3.1 The Journal of Comparative Neurology. Feb, 2004 | Pubmed ID: 14755528 Electron Microscopy of Degenerative Changes in the Chick Basilar Papilla After Gentamicin Exposure The Journal of Comparative Neurology. Mar, 2004 | Pubmed ID: 14750159 Developmental Differences in Susceptibility to Neomycin-induced Hair Cell Death in the Lateral Line Neuromasts of Zebrafish (Danio Rerio) Hearing Research. Dec, 2003 | Pubmed ID: 14644458 Timing and Topography of Nucleus Magnocellularis Innervation by the Cochlear Ganglion The Journal of Comparative Neurology. Nov, 2003 | Pubmed ID: 14566951 Neomycin-induced Hair Cell Death and Rapid Regeneration in the Lateral Line of Zebrafish (Danio Rerio) Journal of the Association for Research in Otolaryngology : JARO. Jun, 2003 | Pubmed ID: 12943374 Ultrastructural Analysis of [3H]thymidine-labeled Cells in the Rat Utricular Macula The Journal of Comparative Neurology. Aug, 2003 | Pubmed ID: 12815755 Hair Cell Regeneration: Winging Our Way Towards a Sound Future Current Opinion in Neurobiology. Feb, 2003 | Pubmed ID: 12593990 Hair Cell Death in the Avian Basilar Papilla: Characterization of the in Vitro Model and Caspase Activation Journal of the Association for Research in Otolaryngology : JARO. Mar, 2003 | Pubmed ID: 12417974 Caspase Activation in Hair Cells of the Mouse Utricle Exposed to Neomycin The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2002 | Pubmed ID: 12351727 Expression of EphB Receptors and EphrinB Ligands in the Developing Chick Auditory Brainstem The Journal of Comparative Neurology. Oct, 2002 | Pubmed ID: 12205709 Vocal Memory and Learning in Adult Bengalese Finches with Regenerated Hair Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2002 | Pubmed ID: 12196601 Auditory System Development: Primary Auditory Neurons and Their Targets Annual Review of Neuroscience. 2002 | Pubmed ID: 12052904 Bcl-2 Overexpression Eliminates Deprivation-induced Cell Death of Brainstem Auditory Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2002 | Pubmed ID: 12040073 Choosing Axonal Real Estate: Location, Location, Location The Journal of Comparative Neurology. Jun, 2002 | Pubmed ID: 12012372 Effects of Age on the Distortion Product Otoacoustic Emission Growth Functions Hearing Research. Jan, 2002 | Pubmed ID: 11788199 Preparation and Culture of Chicken Auditory Brainstem Slices Jason T. Sanchez*1, Armin H. Seidl*1, Edwin W. Rubel1,2, Andres Barria2 1Department of Otolaryngology-Head and Neck Surgery, Virginia Merrill Bloedel Hearing Research Center, University of Washington, 2Department of Physiology and Biophysics, Virginia Merrill Bloedel Hearing Research Center, University of Washington JoVE 2527 Neuroscience
Preparation and Culture of Chicken Auditory Brainstem Slices Jason T. Sanchez*1, Armin H. Seidl*1, Edwin W. Rubel1,2, Andres Barria2 1Department of Otolaryngology-Head and Neck Surgery, Virginia Merrill Bloedel Hearing Research Center, University of Washington, 2Department of Physiology and Biophysics, Virginia Merrill Bloedel Hearing Research Center, University of Washington JoVE 2527 Neuroscience