In JoVE (1)
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Articles by Eggehard Holler in JoVE
Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine? Julia Y. Ljubimova1, Hui Ding1, Jose Portilla-Arias1, Rameshwar Patil1, Pallavi R. Gangalum1, Alexandra Chesnokova1, Satoshi Inoue1, Arthur Rekechenetskiy1, Tala Nassoura1, Keith L. Black1, Eggehard Holler1 1Nanomedicine Research Center, Department of Neurosurgery, Cedars-Sinai Medical Center An example of a nano drug based on polymalic acid is presented towards the rational design of personalized medicine that is applicable to cancer. It describes the synthesis of a nano drug to treat Her2-positive human breast cancer in a nude mouse.