In JoVE (1)
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Articles by Elisa Wistorf in JoVE
A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research Christopher Weidner1, Matthias Steinfath1, Elisa Wistorf1, Michael Oelgeschläger1, Marlon R. Schneider1, Gilbert Schönfelder1,2 1Department of Experimental Toxicology and ZEBET, German Federal Institute for Risk Assessment (BfR), 2Department of Clinical Pharmacology and Toxicology, Charité-Universitätsmedizin Berlin We provide a standardized protocol for the use of gene set enrichment analysis of transcriptomic data to identify an ideal mouse model for translational research. This protocol can be used with DNA microarray and RNA sequencing data and can further be extended to other omics data if data are available.