Articles by Elza van Deel in JoVE
In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography Elza van Deel1,2, Yanto Ridwan1, J. Nicole van Vliet1, Sasha Belenkov3, Jeroen Essers1,4,5 1Department of Genetics, Erasmus MC, Rotterdam, 2Department of Experimental Cardiology, Erasmus MC, Rotterdam, 3PerkinElmer, Inc., 4Department of Vascular Surgery, Erasmus MC, Rotterdam, 5Department of Radiation Oncology, Erasmus MC, Rotterdam This method outlines the use of Quantum Micro-Computed Tomography (MicroCT) to assess cardiac morphology, function, perfusion, metabolism and viability with iodinated contrast agent in mice with experimentally-induced myocardial ischemia. The technique can be applied for non-destructive high-throughput longitudinal in vivo imaging of various animal models of human heart disease.
Other articles by Elza van Deel on PubMed
AT1-receptor Blockade, but Not Renin Inhibition, Reduces Aneurysm Growth and Cardiac Failure in Fibulin-4 Mice Journal of Hypertension. Jan, 2016 | Pubmed ID: 26828783 Increasing evidence supports a role for the angiotensin II-AT1-receptor axis in aneurysm development. Here, we studied whether counteracting this axis via stimulation of AT2 receptors is beneficial. Such stimulation occurs naturally during AT1-receptor blockade with losartan, but not during renin inhibition with aliskiren.