Eric J. Toone Department of Chemistry Duke University Biography Publications Institution JoVE Articles Eric J. Toone has not added a biography. If you are Eric J. Toone and would like to personalize this page please email our Author Liaison for assistance. Publications Improving Upon Nature: Active Site Remodeling Produces Highly Efficient Aldolase Activity Towards Hydrophobic Electrophilic Substrates Biochemistry. Feb, 2012 | Pubmed ID: 22316217 Derivatives of Plant Phenolic Compound Affect the Type III Secretion System of Pseudomonas Aeruginosa Via a GacS-GacA Two-component Signal Transduction System Antimicrobial Agents and Chemotherapy. Jan, 2012 | Pubmed ID: 21968370 Advances in Enzymology and Related Areas of Molecular Biology. Preface Advances in Enzymology and Related Areas of Molecular Biology. 2011 | Pubmed ID: 22220470 Directed Evolution of a Pyruvate Aldolase to Recognize a Long Chain Acyl Substrate Bioorganic & Medicinal Chemistry. Nov, 2011 | Pubmed ID: 21944547 A Multidisciplinary Approach to Probing Enthalpy-entropy Compensation and the Interfacial Mobility Model Journal of the American Chemical Society. Aug, 2011 | Pubmed ID: 21692482 Bacterial Infection Remains a Leading Cause of Death in Both Western and Developing World. Preface Advances in Enzymology and Related Areas of Molecular Biology. 2011 | Pubmed ID: 21692365 Lipooligosaccharide is Required for the Generation of Infectious Elementary Bodies in Chlamydia Trachomatis Proceedings of the National Academy of Sciences of the United States of America. Jun, 2011 | Pubmed ID: 21628561 Soft-lithographic Approach to Functionalization and Nanopatterning Oxide-free Silicon Langmuir : the ACS Journal of Surfaces and Colloids. May, 2011 | Pubmed ID: 21520913 Patterning NHS-terminated SAMs on Germanium Langmuir : the ACS Journal of Surfaces and Colloids. May, 2011 | Pubmed ID: 21504221 Syntheses, Structures and Antibiotic Activities of LpxC Inhibitors Based on the Diacetylene Scaffold Bioorganic & Medicinal Chemistry. Jan, 2011 | Pubmed ID: 21194954 Species-specific and Inhibitor-dependent Conformations of LpxC: Implications for Antibiotic Design Chemistry & Biology. Jan, 2011 | Pubmed ID: 21167751 Thermodynamic Characterization of the Binding Interaction Between the Histone Demethylase LSD1/KDM1 and CoREST Biochemistry. Feb, 2011 | Pubmed ID: 21142040 Identification and Inhibitory Properties of a Novel Ca(2+)/calmodulin Antagonist Biochemistry. May, 2010 | Pubmed ID: 20392081 Catalytic Microcontact Printing on Chemically Functionalized H-terminated Silicon Langmuir : the ACS Journal of Surfaces and Colloids. Feb, 2010 | Pubmed ID: 19950970 Inkless Microcontact Printing on SAMs of Boc- and TBS-protected Thiols Nano Letters. Jan, 2010 | Pubmed ID: 19950928 A Single Step Purification for Autolytic Zinc Proteinases Bioorganic & Medicinal Chemistry Letters. Jan, 2010 | Pubmed ID: 19942433 In Situ Growth of a Stoichiometric PEG-like Conjugate at a Protein's N-terminus with Significantly Improved Pharmacokinetics Proceedings of the National Academy of Sciences of the United States of America. Sep, 2009 | Pubmed ID: 19706892 Eyedrops Containing SA9000 Prodrugs Result in Sustained Reductions in Intraocular Pressure in Rabbits Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics. Jun, 2009 | Pubmed ID: 19456251 C-nitroso Donors of Nitric Oxide The Journal of Organic Chemistry. Feb, 2009 | Pubmed ID: 19146387 Advances in Enzymology and Related Areas of Molecular Biology. Preface Advances in Enzymology and Related Areas of Molecular Biology. 2009 | Pubmed ID: 18990826 Characterization and Crystal Structure of Escherichia Coli KDPGal Aldolase Bioorganic & Medicinal Chemistry. Jan, 2008 | Pubmed ID: 17981470 Mutagenesis of the Phosphate-binding Pocket of KDPG Aldolase Enhances Selectivity for Hydrophobic Substrates Protein Science : a Publication of the Protein Society. Nov, 2007 | Pubmed ID: 17962400 Inkless Microcontact Printing on Self-assembled Monolayers of Fmoc-protected Aminothiols Journal of the American Chemical Society. Nov, 2007 | Pubmed ID: 17949005 Biocatalytic Microcontact Printing The Journal of Organic Chemistry. Sep, 2007 | Pubmed ID: 17705546 Pyruvate Aldolases in Chiral Carbon-carbon Bond Formation Nature Protocols. 2007 | Pubmed ID: 17641651 A Stochastic, Cantilever Approach to the Evaluation of Solution Phase Thermodynamic Quantities Proceedings of the National Academy of Sciences of the United States of America. Feb, 2007 | Pubmed ID: 17307881 Binding of Warfarin Influences the Acid-base Equilibrium of H242 in Sudlow Site I of Human Serum Albumin Photochemistry and Photobiology. Sep-Oct, 2006 | Pubmed ID: 16563025 Mechanism of the Class I KDPG Aldolase Bioorganic & Medicinal Chemistry. May, 2006 | Pubmed ID: 16403639 C-nitroso Compounds: Synthesis, Physicochemical Properties and Biological Activities Current Topics in Medicinal Chemistry. 2005 | Pubmed ID: 16101429 Nitrosonium-catalyzed Decomposition of S-nitrosothiols in Solution: a Theoretical and Experimental Study Journal of the American Chemical Society. Aug, 2005 | Pubmed ID: 16076198 A Small-molecule Inhibitor of Isoprenylcysteine Carboxyl Methyltransferase with Antitumor Activity in Cancer Cells Proceedings of the National Academy of Sciences of the United States of America. Mar, 2005 | Pubmed ID: 15784746 A Bacterial Selection for the Directed Evolution of Pyruvate Aldolases Bioorganic & Medicinal Chemistry. Aug, 2004 | Pubmed ID: 15246084 Calorimetric Evaluation of Protein-carbohydrate Affinities Methods in Enzymology. 2003 | Pubmed ID: 12968383 Solid-phase Synthesis for the Identification of High-affinity Bivalent Lectin Ligands The Journal of Organic Chemistry. Jul, 2003 | Pubmed ID: 12868911 Additivity and the Physical Basis of Multivalency Effects: a Thermodynamic Investigation of the Calcium EDTA Interaction Journal of the American Chemical Society. Jun, 2003 | Pubmed ID: 12797810 Nitroxyl Disulfides, Novel Intermediates in Transnitrosation Reactions Journal of the American Chemical Society. Jun, 2003 | Pubmed ID: 12783550 The Decomposition of Thionitrites Current Opinion in Chemical Biology. Dec, 2002 | Pubmed ID: 12470731 The Cluster Glycoside Effect Chemical Reviews. Feb, 2002 | Pubmed ID: 11841254 Cloning, Isolation and Characterization of the Thermotoga Maritima KDPG Aldolase Bioorganic & Medicinal Chemistry. Mar, 2002 | Pubmed ID: 11814840 Stereospecific Preparation of the N-Terminal Amino Acid Moiety of Nikkomycins K(X) and K(Z) Via a Multiple Enzyme Synthesis The Journal of Organic Chemistry. Nov, 1997 | Pubmed ID: 11671888 Blød Litografiske funktionalisering og mønster oxydfri silicium og germanium Carleen M. Bowers1, Eric J. Toone1, Robert L. Clark2, Alexander A. Shestopalov3 1Department of Chemistry, Duke University, 2Hajim School of Engineering and Applied Sciences, University of Rochester, 3Department of Chemical Engineering, University of Rochester JoVE 3478 Bioengineering
Blød Litografiske funktionalisering og mønster oxydfri silicium og germanium Carleen M. Bowers1, Eric J. Toone1, Robert L. Clark2, Alexander A. Shestopalov3 1Department of Chemistry, Duke University, 2Hajim School of Engineering and Applied Sciences, University of Rochester, 3Department of Chemical Engineering, University of Rochester JoVE 3478 Bioengineering