Articles by Eric W. Martin in JoVE
同时捕获实时图像在两个发射通道采用了双摄像头发射分光系统：应用到细胞粘附 Grady E. Carlson1, Eric W. Martin2, Monica M. Burdick1,2 1Department of Chemical and Biomolecular Engineering, Russ College of Engineering and Technology, Ohio University, 2Biomedical Engineering Program, Ohio University 双摄像头发射分光系统，双色荧光显微镜生成具有出色的光学分辨率和时间分辨率，一定的活细胞检测的要求，包括平行板流动腔粘连检测的实时图像序列。当软件被用来从合并收购的同时发射通道的图像，伪彩色图像序列产生。
Isolation and Characterization Of Chimeric Human Fc-expressing Proteins Using Protein A Membrane Adsorbers And A Streamlined Workflow Monica M. Burdick1,2, Nathan M. Reynolds1,2, Eric W. Martin2, Jacquelyn V. Hawes1, Grady E. Carlson1, Chaz M. Cuckler1, Michael C. Bates1, Steven R. Barthel3, Charles J. Dimitroff3 1Department of Chemical and Biomolecular Engineering, Ohio University, 2Biomedical Engineering Program, Russ College of Engineering and Technology, Ohio University, 3 Compared with traditional affinity chromatography using protein A agarose bead-packed columns, protein A membrane adsorbers can significantly speed laboratory-scale isolation of antibodies and other Fc fragment-expressing proteins. Appropriate analysis and quantification methods can further accelerate protein processing, allowing isolation/characterization to be completed in one workday, instead of 20+ work hours.
Other articles by Eric W. Martin on PubMed
Low Dose Hard X-ray Contact Microscopy Assisted by a Photoelectric Conversion Layer AIP Advances. Apr, 2013 | Pubmed ID: 23837131 Hard x-ray contact microscopy provides images of dense samples at resolutions of tens of nanometers. However, the required beam intensity can only be delivered by synchrotron sources. We report on the use of a gold photoelectric conversion layer to lower the exposure dose by a factor of 40 to 50, allowing hard x-ray contact microscopy to be performed with a compact x-ray tube. We demonstrate the method in imaging the transmission pattern of a type of hard x-ray grating that cannot be fitted into conventional x-ray microscopes due to its size and shape. Generally the method is easy to implement and can record images of samples in the hard x-ray region over a large area in a single exposure, without some of the geometric constraints associated with x-ray microscopes based on zone-plate or other magnifying optics.