Erin L. Seifert

Publications

• Frataxin Deficiency Lowers Lean Mass and Triggers the Integrated Stress Response in Skeletal Muscle
  JCI Insight. May, 2022  |   Pubmed ID: 35531957
• A Novel Role for DNA-PK in Metabolism by Regulating Glycolysis in Castration-Resistant Prostate Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2022  |   Pubmed ID: 35078861
• Adaptation of the Heart to Frataxin Depletion: Evidence That Integrated Stress Response Can Predominate over MTORC1 Activation
  Human Molecular Genetics. Sep, 2021  |   Pubmed ID: 34550363
• Quantification of Lactoyl-CoA (lactyl-CoA) by Liquid Chromatography Mass Spectrometry in Mammalian Cells and Tissues
  Open Biology. 09, 2020  |   Pubmed ID: 32961073
• Multiple Mitochondrial Thioesterases Have Distinct Tissue and Substrate Specificity and CoA Regulation, Suggesting Unique Functional Roles
  The Journal of Biological Chemistry. 12, 2019  |   Pubmed ID: 31676684
• Dysregulation of Mitochondrial Ca Uptake and Sarcolemma Repair Underlie Muscle Weakness and Wasting in Patients and Mice Lacking MICU1
  Cell Reports. 10, 2019  |   Pubmed ID: 31665639
• Loss of PINK1 Causes Age-dependent Decrease of Dopamine Release and Mitochondrial Dysfunction
  Neurobiology of Aging. 03, 2019  |   Pubmed ID: 30504091
• Bicarbonate Recycling by HIF-1-Dependent Carbonic Anhydrase Isoforms 9 and 12 Is Critical in Maintaining Intracellular PH and Viability of Nucleus Pulposus Cells
  Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. 02, 2018  |   Pubmed ID: 28940640
• Posttranscriptional Upregulation of IDH1 by HuR Establishes a Powerful Survival Phenotype in Pancreatic Cancer Cells
  Cancer Research. 08, 2017  |   Pubmed ID: 28652247
• MSTO1 is a Cytoplasmic Pro-mitochondrial Fusion Protein, Whose Mutation Induces Myopathy and Ataxia in Humans
  EMBO Molecular Medicine. 07, 2017  |   Pubmed ID: 28554942
• Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB1 Signaling Axis
  Cancer Research. May, 2017  |   Pubmed ID: 28522753
• Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU
  Cell Reports. 03, 2017  |   Pubmed ID: 28273446
• Natural and Induced Mitochondrial Phosphate Carrier Loss: DIFFERENTIAL DEPENDENCE OF MITOCHONDRIAL METABOLISM AND DYNAMICS AND CELL SURVIVAL ON THE EXTENT OF DEPLETION
  The Journal of Biological Chemistry. Dec, 2016  |   Pubmed ID: 27780865
• Hypoxia Promotes Noncanonical Autophagy in Nucleus Pulposus Cells Independent of MTOR and HIF1A Signaling
  Autophagy. 09, 2016  |   Pubmed ID: 27314664
• MICU1 Regulation of Mitochondrial Ca(2+) Uptake Dictates Survival and Tissue Regeneration
  Nature Communications. Mar, 2016  |   Pubmed ID: 26956930
• Mitochondrial Functions Modulate Neuroendocrine, Metabolic, Inflammatory, and Transcriptional Responses to Acute Psychological Stress
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2015  |   Pubmed ID: 26627253
• IL-15Rα is a Determinant of Muscle Fuel Utilization, and Its Loss Protects Against Obesity
  American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Oct, 2015  |   Pubmed ID: 26269523
• The Mitochondrial Phosphate Carrier: Role in Oxidative Metabolism, Calcium Handling and Mitochondrial Disease
  Biochemical and Biophysical Research Communications. Aug, 2015  |   Pubmed ID: 26091567
• Functional Mitochondrial Analysis in Acute Brain Sections from Adult Rats Reveals Mitochondrial Dysfunction in a Rat Model of Migraine
  American Journal of Physiology. Cell Physiology. Dec, 2014  |   Pubmed ID: 25252946
• Lower Mitochondrial Proton Leak and Decreased Glutathione Redox in Primary Muscle Cells of Obese Diet-resistant Versus Diet-sensitive Humans
  The Journal of Clinical Endocrinology and Metabolism. Nov, 2014  |   Pubmed ID: 25148230
• Acyl-CoA Thioesterase-2 Facilitates Mitochondrial Fatty Acid Oxidation in the Liver
  Journal of Lipid Research. Dec, 2014  |   Pubmed ID: 25114170
• Reliance of ER-mitochondrial Calcium Signaling on Mitochondrial EF-hand Ca2+ Binding Proteins: Miros, MICUs, LETM1 and Solute Carriers
  Current Opinion in Cell Biology. Aug, 2014  |   Pubmed ID: 24999559
• The Retinal Pigment Epithelium Utilizes Fatty Acids for Ketogenesis
  The Journal of Biological Chemistry. Jul, 2014  |   Pubmed ID: 24898254
• MICU1 Controls Both the Threshold and Cooperative Activation of the Mitochondrial Ca²⁺ Uniporter
  Cell Metabolism. Jun, 2013  |   Pubmed ID: 23747253