Ernst J. Wolvetang Department Name Institution Name Biography Publications Institution JoVE Articles Ernst J. Wolvetang has not added a biography. If you are Ernst J. Wolvetang and would like to personalize this page please email our Author Liaison for assistance. Publications Impaired Signaling for Neuromuscular Synaptic Maintenance is a Feature of Motor Neuron Disease Acta Neuropathologica Communications. Apr, 2022 | Pubmed ID: 35468848 Neural Epidermal Growth Factor-Like Like Protein 2 Is Expressed in Human Oligodendroglial Cell Types Frontiers in Cell and Developmental Biology. Month, 2022 | Pubmed ID: 35265611 Exploring Aging Interventions in Human Brain Organoids Aging. 02, 2022 | Pubmed ID: 35247254 Human Induced Pluripotent Stem Cells Generated from Epilepsy Patients for Use As in Vitro Models for Drug Screening Stem Cell Research. 04, 2022 | Pubmed ID: 35074713 Generation of Induced Pluripotent Stem Cell Lines from Peripheral Blood Mononuclear Cells of Three Drug Resistant and Three Drug Responsive Epilepsy Patients Stem Cell Research. 10, 2021 | Pubmed ID: 34649201 Reprogramming of Human Olfactory Neurosphere-derived Cells from Olfactory Mucosal Biopsies of a Control Cohort Stem Cell Research. 10, 2021 | Pubmed ID: 34507143 Ataxia Telangiectasia IPSC Line Generated from a Patient Olfactory Biopsy Identifies Novel Disease-causing Mutations Stem Cell Research. 10, 2021 | Pubmed ID: 34507142 Inhibition of the CGAS-STING Pathway Ameliorates the Premature Senescence Hallmarks of Ataxia-Telangiectasia Brain Organoids Aging Cell. 09, 2021 | Pubmed ID: 34459078 Klotho Inhibits Neuronal Senescence in Human Brain Organoids NPJ Aging and Mechanisms of Disease. Aug, 2021 | Pubmed ID: 34341344 Rapid and Efficient Generation of Myelinating Human Oligodendrocytes in Organoids Frontiers in Cellular Neuroscience. Month, 2021 | Pubmed ID: 33815061 Use of Human Induced Pluripotent Stem Cells and Kidney Organoids To Develop a Cysteamine/mTOR Inhibition Combination Therapy for Cystinosis Journal of the American Society of Nephrology : JASN. 05, 2020 | Pubmed ID: 32198276 Correction of ATM Mutations in IPS Cells from Two Ataxia-telangiectasia Patients Restores DNA Damage and Oxidative Stress Responses Human Molecular Genetics. 04, 2020 | Pubmed ID: 32037450 Multivariate Patterning of Human Pluripotent Cells Under Perfusion Reveals Critical Roles of Induced Paracrine Factors in Kidney Organoid Development Science Advances. 01, 2020 | Pubmed ID: 31934619 Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells from the Tasmanian Devil () Express Immunomodulatory Factors and a Tropism Toward Devil Facial Tumor Cells Stem Cells and Development. 01, 2020 | Pubmed ID: 31709909 Author Correction: Reprogramming Triggers Endogenous L1 and Alu Retrotransposition in Human Induced Pluripotent Stem Cells Nature Communications. 12, 2018 | Pubmed ID: 30568248 The Impact of APP on Alzheimer-like Pathogenesis and Gene Expression in Down Syndrome IPSC-Derived Neurons Stem Cell Reports. 07, 2018 | Pubmed ID: 29861166 Neuronal Lipid Metabolism: Multiple Pathways Driving Functional Outcomes in Health and Disease Frontiers in Molecular Neuroscience. Month, 2018 | Pubmed ID: 29410613 Lentiviral Reprogramming of A-T Patient Fibroblasts to Induced Pluripotent Stem Cells Methods in Molecular Biology (Clifton, N.J.). Month, 2017 | Pubmed ID: 28477135 Complement C5aR1 Signaling Promotes Polarization and Proliferation of Embryonic Neural Progenitor Cells Through PKCζ The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 05, 2017 | Pubmed ID: 28455369 The Long Non-coding RNA NEAT1 is Responsive to Neuronal Activity and is Associated with Hyperexcitability States Scientific Reports. 01, 2017 | Pubmed ID: 28054653 Induction of Human IPSC-Derived Cardiomyocyte Proliferation Revealed by Combinatorial Screening in High Density Microbioreactor Arrays Scientific Reports. Apr, 2016 | Pubmed ID: 27097795 Reprogramming Triggers Endogenous L1 and Alu Retrotransposition in Human Induced Pluripotent Stem Cells Nature Communications. Jan, 2016 | Pubmed ID: 26743714 Mechanisms of Long Non-coding RNAs in Mammalian Nervous System Development, Plasticity, Disease, and Evolution Neuron. Dec, 2015 | Pubmed ID: 26637795 Generation of Footprint-Free Induced Pluripotent Stem Cells from Human Fibroblasts Using Episomal Plasmid Vectors Methods in Molecular Biology (Clifton, N.J.). Month, 2015 | Pubmed ID: 26621587 Kidney Organoids from Human IPS Cells Contain Multiple Lineages and Model Human Nephrogenesis Nature. Oct, 2015 | Pubmed ID: 26444236 A New Model to Study Neurodegeneration in Ataxia Oculomotor Apraxia Type 2 Human Molecular Genetics. Oct, 2015 | Pubmed ID: 26231220 Advances in Reprogramming to Pluripotency Current Stem Cell Research & Therapy. Month, 2015 | Pubmed ID: 25697500 Isolation of Contractile Cardiomyocytes from Human Pluripotent Stem-cell-derived Cardiomyogenic Cultures Using a Human NCX1-EGFP Reporter Stem Cells and Development. Jan, 2015 | Pubmed ID: 25075536 Opportunities and Limitations of Modelling Alzheimer's Disease with Induced Pluripotent Stem Cells Journal of Clinical Medicine. Dec, 2014 | Pubmed ID: 26237606 Transgenic Human ES and IPS Reporter Cell Lines for Identification and Selection of Pluripotent Stem Cells in Vitro Stem Cell Research. Sep, 2014 | Pubmed ID: 25108530 Will Brain Cells Derived from Induced Pluripotent Stem Cells or Directly Converted from Somatic Cells (iNs) Be Useful for Schizophrenia Research? Schizophrenia Bulletin. Sep, 2013 | Pubmed ID: 23884351 Full Factorial Screening of Human Embryonic Stem Cell Maintenance with Multiplexed Microbioreactor Arrays Biotechnology Journal. Jul, 2013 | Pubmed ID: 23813764 Arrayed Cellular Environments for Stem Cells and Regenerative Medicine Biotechnology Journal. Feb, 2013 | Pubmed ID: 22890848 Microbioreactor Arrays for Full Factorial Screening of Exogenous and Paracrine Factors in Human Embryonic Stem Cell Differentiation PloS One. Month, 2012 | Pubmed ID: 23300662 Small Molecule Mesengenic Induction of Human Induced Pluripotent Stem Cells to Generate Mesenchymal Stem/stromal Cells Stem Cells Translational Medicine. Feb, 2012 | Pubmed ID: 23197756 Tumor-suppressor Gene Promoter Hypermethylation in Saliva of Head and Neck Cancer Patients Translational Oncology. Oct, 2012 | Pubmed ID: 23066440 Differential Mesengenic Potential and Expression of Stem Cell-fate Modulators in Mesenchymal Stromal Cells from Human-term Placenta and Bone Marrow Journal of Cellular Physiology. Sep, 2012 | Pubmed ID: 22105866 A Defined Medium and Substrate for Expansion of Human Mesenchymal Stromal Cell Progenitors That Enriches for Osteo- and Chondrogenic Precursors Stem Cells and Development. Jan, 2011 | Pubmed ID: 20446813 Ascorbate Promotes Epigenetic Activation of CD30 in Human Embryonic Stem Cells Stem Cells (Dayton, Ohio). Oct, 2010 | Pubmed ID: 20715184 Long Term Culture of Human Embryonic Stem Cells on Recombinant Vitronectin in Ascorbate Free Media Biomaterials. Nov, 2010 | Pubmed ID: 20674971 Defined High Protein Content Surfaces for Stem Cell Culture Biomaterials. Jul, 2010 | Pubmed ID: 20378164 Multiplexed Staining of Live Human Embryonic Stem Cells for Flow Cytometric Analysis of Pluripotency Markers Stem Cells and Development. Oct, 2009 | Pubmed ID: 19397457 Robust and Highly Reproducible Generation of Cortical Brain Organoids for Modelling Brain Neuronal Senescence In Vitro Mohammed R. Shaker*1, Zoe L. Hunter*1, Ernst J. Wolvetang1 1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland JoVE 63714 Neuroscience
Robust and Highly Reproducible Generation of Cortical Brain Organoids for Modelling Brain Neuronal Senescence In Vitro Mohammed R. Shaker*1, Zoe L. Hunter*1, Ernst J. Wolvetang1 1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland JoVE 63714 Neuroscience
