Other Publications (8)
- Journal of Molecular Spectroscopy
- Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
- TÃ¼rk Psikiyatri Dergisi = Turkish Journal of Psychiatry
- International Journal of Surgical Pathology
- Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis
- Journal of Medicinal Chemistry
- Journal of Clinical and Diagnostic Research : JCDR
- BMJ Case Reports
Articles by Ewa Król in JoVE
FtsZ Polymerization Assays: Simple Protocols and Considerations Ewa Król1, Dirk-Jan Scheffers1 1Department of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen Polymerization of FtsZ is essential for bacterial cell division. In this report, we detail simple protocols to monitor FtsZ polymerization activity and discuss the influence of buffer composition. The protocols can be used to study the interaction of FtsZ with regulatory proteins or antibacterial drugs that affect FtsZ polymerization.
Other articles by Ewa Król on PubMed
Antisymmetric Amino-Wagging Band of Hydrazine Up to K' = 13 Levels Journal of Molecular Spectroscopy. Dec, 1997 | Pubmed ID: 9446763 A newly recorded high-resolution infrared spectrum of hydrazine has been studied in the 729-1198 cm-1 region (the nu12 antisymmetric wagging band) with a resolution of 0.002 cm-1. About 1350 transitions with K' from 7 to 13 have been newly assigned and about 2350 transitions with lower values of K' reanalyzed with the improved precision. The effective parameters have been calculated separately for each value of K' using the Hougen-Ohashi hamiltonian for hydrazine. The extended assignment completes the analysis of the nu12 band of hydrazine. Copyright 1997 Academic Press. Copyright 1997Academic Press
Parapharyngeal Second Branchial Cyst: A Case Report Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India. Jul, 2006 | Pubmed ID: 23120316 Branchial cleft cysts extending to the lateral wall of the pharynx are rare. An eight year old female child presented with a cystic swelling in the left parotid region. A bluish cyst was seen anterior to the anterior pillar of left tonsil. CT scan showed the cyst extending into left parapharyngeal space. External part of the cyst was excised via a transcervical approach and the internal part was marsupalised per orally.
[The Mortality Rate Among Patients with Delirium 6 Months After Diagnosis by a Consultation-liaison Psychiatric Team] TÃ¼rk Psikiyatri Dergisi = Turkish Journal of Psychiatry. 2012 | Pubmed ID: 22949288 Data from Western countries suggest that delirium is associated with a high rate of mortality; however, the mortality rate in patients with delirium in India has not been studied. The aim of this study is to determine the mortality rate among a group of hospitalized patients with delirium 6 months after being diagnosed with delirium.
Significance of Incidentally Detected Thyroid Tissue in Lymph Nodes of Neck Dissections in Patients With Head and Neck Carcinoma International Journal of Surgical Pathology. Jun, 2012 | Pubmed ID: 22674918 Background. The incidental discovery of thyroid tissue in lymph nodes of neck dissections performed for a separate primary head and neck cancer is an unusual clinical entity. Careful screening of large number of lymph nodes in the neck dissection specimens by the pathologist is critical in picking up such cases. There is controversy regarding clinical significance of such incidentally detected thyroid tissue in cervical nodes as to whether these represent benign inclusions or whether they represent metastatic focus of an underlying thyroid cancer. The appropriate clinical approach in such cases is less clear because it occurs in the context of another malignancy, usually squamous cell carcinomas with a more aggressive potential. Materials and methods. On reviewing the records of 1602 neck dissections done in patients with head and neck cancers over the years 2007-2011, this study identified 5 patients with incidentally detected thyroid tissue with features of malignancy in cervical lymph nodes. Subsequent thyroidectomies done in 4 cases showed primary thyroid cancer. Conclusion. The study's results emphasize the need for the clinician to do an accurate reevaluation and follow-up of patients with incidental occult metastasis for detection of primary thyroid tumor. A thorough sampling and screening of lymph nodes in neck dissection specimens by the pathologist is also essential. Incidentally discovered thyroid tissue in cervical lymph nodes need not always be benign inclusions. Aggressive therapy, however, may not be needed in all cases.
The Relationship Between Mean Platelet Volume with Metabolic Syndrome in Obese Individuals Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis. Jul, 2012 | Pubmed ID: 22473052 The metabolic syndrome is closely associated with atherosclerotic risk factors and increased mortality. Mean platelet volume (MPV) is an indicator of platelet activation which also shows a close relationship with cardiovascular risk factors, such as diabetes mellitus, hypertension, hypercholesterolemia, obesity, metabolic syndrome. The aim of this study was to investigate the correlates of metabolic syndrome, its components and MPV adjusted for obesity in a large population study. A total of 2298 individuals with a mean age of 50 (age range 18-92) were interviewed. Nine hundred and twenty obese participants, who had BMI 30 kg/mÂ² or more, further evaluated for the presence of metabolic syndrome. Five hundred and thirteen [396 women (70.2%)] had metabolic syndrome and the rest 407 individuals [324 women (79.6%)] served as the control group. The BMI, SBP, DBP, waist circumference, fasting plasma glucose, visceral fat, total cholesterol, high-density lipoprotein-cholesterol, and triglyceride was higher significantly in metabolic syndrome group (P = 0.002 for BMI and P < 0.001 for the others). No significant difference was observed between groups regarding low-density lipoprotein cholesterol, white blood cells, platelet counts, MPV, hematocrit and hemoglobin (P > 0.05 for all). The presence of metabolic syndrome and its components do not constitute a difference in MPV values in obese patients with a BMI 30 kg/mÂ² or more.
Azaindoles: Non-covalent DprE1 Inhibitors from Scaffold Morphing Efforts Kill Mycobacterium Tuberculosis and Are Efficacious In Vivo Journal of Medicinal Chemistry. Nov, 2013 | Pubmed ID: 24215368 We report 1,4-azaindoles, as a new inhibitor class that kills Mycobacterium tuberculosis in vitro and demonstrates efficacy in mouse tuberculosis models. The series emerged from scaffold morphing efforts and was demonstrated to non-covalently inhibit decaprenylphosphoryl-β-D-ribose2'-epimerase (DprE1). With "drug-like" properties and no expectation of pre-existing resistance in the clinic, this chemical class has the potential to be developed as a therapy for drug sensitive and drug resistant tuberculosis.
The Evaluation of Micronutrients and Oxidative Stress and Their Relationship with the Lipid Profile in Healthy Adults Journal of Clinical and Diagnostic Research : JCDR. Jul, 2013 | Pubmed ID: 23998054 Introduction: Micronutrients are nutrients which are required by humans and other living beings throughout life in small quantities, to orchestrate a whole range of physiological functions, which the organism itself cannot produce. Therefore, the present study was undertaken to evaluate the status of the micronutrients, oxidative stress, and the lipid profile in healthy adults. Material and Methods: The present study was conducted after getting the institutional ethical clearance and informed written consents from all the participants. The estimation of copper and zinc was done by the atomic absorption spectrophotometer method,the total antioxidant status was assessed by the phosphomolybdenum method, MDA was evaluated by the Malondialdehyde method, total cholesterol was evaluated by the CHOD-POD method, HDL-cholesterol was evaluated by the precipitation end point method, and total triglycerides were evaluated by the GPO-POD method. The data was analysed by one way ANOVA, followed by Pearson's correlation. Result: We observed significantly increased (p