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Articles by Federico Paliotto in JoVE
Personalized Needles for Microinjections in the Rodent Brain Giovanna Paolone*1, Chiara Falcicchia*1, Gianluca Verlengia*1, Mario Barbieri1, Anna Binaschi1, Federico Paliotto1, Beatrice Paradiso1, Marie Soukupova1, Silvia Zucchini1,2, Michele Simonato1,2 1Department of Medical Sciences, Section of Pharmacology, and National Institute of Neurosciences, University of Ferrara, 2Laboratory for the Technologies for Advanced Therapies (LTTA), University of Ferrara We describe here a protocol for microinjection in the rodent brain that uses quartz needles. These needles do not produce detectable tissue damage and ensure reliable delivery even in deep regions. Moreover, they can be adapted to research needs by personalized designs and can be re-used.