Felipe Court Center for Integrative Biology Universidad Mayor Biography Publications Institution JoVE Articles Felipe Court has not added a biography. If you are Felipe Court and would like to personalize this page please email our Author Liaison for assistance. Publications Commentary on "PANoptosis-like Cell Death in Ischemia/reperfusion Injury of Retinal Neurons" Neural Regeneration Research. Feb, 2023 | Pubmed ID: 35900426 Aβ Oligomers Trigger Necroptosis-mediated Neurodegeneration Via Microglia Activation in Alzheimer's Disease Acta Neuropathologica Communications. 03, 2022 | Pubmed ID: 35264247 Enhanced Activity of Exportin-1/CRM1 in Neurons Contributes to Autophagy Dysfunction and Senescent Features in Old Mouse Brain Oxidative Medicine and Cellular Longevity. 2021 | Pubmed ID: 34434486 Author Correction: IRE1α Governs Cytoskeleton Remodeling and Cell Migration Through a Direct Interaction with Filamin A Nature Cell Biology. May, 2021 | Pubmed ID: 33907311 Dementia in Latin America: Paving the Way Toward a Regional Action Plan Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 02, 2021 | Pubmed ID: 33634602 New Insights on the Molecular Mechanisms of Collateral Sprouting After Peripheral Nerve Injury Neural Regeneration Research. Sep, 2021 | Pubmed ID: 33510065 GERO Cohort Protocol, Chile, 2017-2022: Community-based Cohort of Functional Decline in Subjective Cognitive Complaint Elderly BMC Geriatrics. 11, 2020 | Pubmed ID: 33238908 Axonal Degeneration in AD: The Contribution of Aβ and Tau Frontiers in Aging Neuroscience. 2020 | Pubmed ID: 33192476 Collateral Sprouting of Peripheral Sensory Neurons Exhibits a Unique Transcriptomic Profile Molecular Neurobiology. Oct, 2020 | Pubmed ID: 32696431 Ex Vivo Analysis of Axonal Degeneration Using Sciatic and Optic Nerve Preparations Methods in Molecular Biology (Clifton, N.J.). 2020 | Pubmed ID: 32524481 Schwann Cell Reprogramming into Repair Cells Increases MiRNA-21 Expression in Exosomes Promoting Axonal Growth Journal of Cell Science. 06, 2020 | Pubmed ID: 32409566 The Necroptosis Pathway and Its Role in Age-related Neurodegenerative Diseases: Will It Open Up New Therapeutic Avenues in the Next Decade? Expert Opinion on Therapeutic Targets. 07, 2020 | Pubmed ID: 32310729 Correction: The Necroptosis Machinery Mediates Axonal Degeneration in a Model of Parkinson Disease Cell Death and Differentiation. Jul, 2020 | Pubmed ID: 32047275 The Necroptosis Machinery Mediates Axonal Degeneration in a Model of Parkinson Disease Cell Death and Differentiation. 04, 2020 | Pubmed ID: 31591470 The P75 Neurotrophin Receptor is Required to Organize the Mature Neuromuscular Synapse by Regulating Synaptic Vesicle Availability Acta Neuropathologica Communications. 09, 2019 | Pubmed ID: 31514753 Publisher Correction: Non-canonical Function of IRE1α Determines Mitochondria-associated Endoplasmic Reticulum Composition to Control Calcium Transfer and Bioenergetics Nature Cell Biology. Jul, 2019 | Pubmed ID: 31201389 Altered Mitochondrial Bioenergetics Are Responsible for the Delay in Wallerian Degeneration Observed in Neonatal Mice Neurobiology of Disease. 10, 2019 | Pubmed ID: 31176719 Non-canonical Function of IRE1α Determines Mitochondria-associated Endoplasmic Reticulum Composition to Control Calcium Transfer and Bioenergetics Nature Cell Biology. 06, 2019 | Pubmed ID: 31110288 Compartmentalized Necroptosis Activation in Excitotoxicity-induced Axonal Degeneration: a Novel Mechanism Implicated in Neurodegenerative Disease Pathology Neural Regeneration Research. Aug, 2019 | Pubmed ID: 30964063 Axonal Degeneration Is Mediated by Necroptosis Activation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 05, 2019 | Pubmed ID: 30850513 Axonal Degeneration Induced by Glutamate Excitotoxicity is Mediated by Necroptosis Journal of Cell Science. 11, 2018 | Pubmed ID: 30333135 Publisher Correction: IRE1α Governs Cytoskeleton Remodelling and Cell Migration Through a Direct Interaction with Filamin A Nature Cell Biology. Oct, 2018 | Pubmed ID: 30089843 Mitochondria and Calcium Regulation As Basis of Neurodegeneration Associated With Aging Frontiers in Neuroscience. 2018 | Pubmed ID: 30057523 IRE1α Governs Cytoskeleton Remodelling and Cell Migration Through a Direct Interaction with Filamin A Nature Cell Biology. 08, 2018 | Pubmed ID: 30013108 The Inhibition of CTGF/CCN2 Activity Improves Muscle and Locomotor Function in a Murine ALS Model Human Molecular Genetics. 08, 2018 | Pubmed ID: 29860398 Teased Fiber Preparation of Myelinated Nerve Fibers from Peripheral Nerves for Vital Dye Staining and Immunofluorescence Analysis Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29546717 Purification of Exosomes from Primary Schwann Cells, RNA Extraction, and Next-Generation Sequencing of Exosomal RNAs Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29546715 In Vitro Analysis of the Role of Schwann Cells on Axonal Degeneration and Regeneration Using Sensory Neurons from Dorsal Root Ganglia Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29546712 A Dual Role for Integrin α6β4 in Modulating Hereditary Neuropathy with Liability to Pressure Palsies Journal of Neurochemistry. 05, 2018 | Pubmed ID: 29315582 Molecular Analysis of Axonal-intrinsic and Glial-associated Co-regulation of Axon Degeneration Cell Death & Disease. 11, 2017 | Pubmed ID: 29120410 Disulfide Cross-linked Multimers of TDP-43 and Spinal Motoneuron loss in a TDP-43 ALS/FTD Mouse Model Scientific Reports. 10, 2017 | Pubmed ID: 29079747 Axonal Degeneration During Aging and Its Functional Role in Neurodegenerative Disorders Frontiers in Neuroscience. 2017 | Pubmed ID: 28928628 Herpes Simplex Virus Type 1 Neuronal Infection Perturbs Golgi Apparatus Integrity Through Activation of Src Tyrosine Kinase and Dyn-2 GTPase Frontiers in Cellular and Infection Microbiology. 2017 | Pubmed ID: 28879169 Schwann Cell and Axon: An Interlaced Unit-From Action Potential to Phenotype Expression Advances in Experimental Medicine and Biology. 2016 | Pubmed ID: 27714690 Origin of Axonal Proteins: Is the Axon-schwann Cell Unit a Functional Syncytium? Cytoskeleton (Hoboken, N.J.). Oct, 2016 | Pubmed ID: 27490284 Bursting the Unfolded Protein Response Accelerates Axonal Regeneration Neural Regeneration Research. Jun, 2016 | Pubmed ID: 27482204 Injury to the Nervous System: A Look into the ER Brain Research. 10, 2016 | Pubmed ID: 27117870 Altered Potassium Channel Distribution and Composition in Myelinated Axons Suppresses Hyperexcitability Following Injury ELife. Apr, 2016 | Pubmed ID: 27033551 Calcium Release from Intra-axonal Endoplasmic Reticulum Leads to Axon Degeneration Through Mitochondrial Dysfunction The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2014 | Pubmed ID: 24849352 Analyzing the Parkinson's Disease Mouse Model Induced by Adeno-associated Viral Vectors Encoding Human α-Synuclein Daniela Elgueta1, Ornella Chovar1, Valentina Ugalde1, Vanesa Sánchez-Guajardo1, Alejandra Catenaccio2, Felipe Court2,3,4, Rodrigo Pacheco1,5 1Laboratorio de Neuroinmunología, Fundación Ciencia & Vida, 2Center for Integrative Biology, Universidad Mayor, 3FONDAP Geroscience Center for Brain Health and Metabolism, 4Buck Institute for Research on Ageing, 5Facultad de Medicina y Ciencia, Universidad San Sebastián JoVE 63313 Neuroscience
Analyzing the Parkinson's Disease Mouse Model Induced by Adeno-associated Viral Vectors Encoding Human α-Synuclein Daniela Elgueta1, Ornella Chovar1, Valentina Ugalde1, Vanesa Sánchez-Guajardo1, Alejandra Catenaccio2, Felipe Court2,3,4, Rodrigo Pacheco1,5 1Laboratorio de Neuroinmunología, Fundación Ciencia & Vida, 2Center for Integrative Biology, Universidad Mayor, 3FONDAP Geroscience Center for Brain Health and Metabolism, 4Buck Institute for Research on Ageing, 5Facultad de Medicina y Ciencia, Universidad San Sebastián JoVE 63313 Neuroscience
